[Hub]/) : Traits : Asthma (self-reported) :

chr6:134,905,567-136,516,257

Best TWAS P=2e-13 · Best GWAS P=2.54e-09 conditioned to 0.714

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous AHI1 0.40 0.27 lasso 5 0.34 1.0e-28 4.0 -5.6 1.8e-08 -0.68 0.98 0.02 FALSE
2 GTEx Adipose Visceral Omentum AHI1 0.17 0.18 lasso 4 0.19 5.6e-10 4.0 -5.1 2.9e-07 -0.58 0.85 0.13 FALSE
3 GTEx Artery Aorta AHI1 0.28 0.01 enet 27 0.08 3.2e-05 4.0 -5.8 6.8e-09 -0.74 0.03 0.94 FALSE
4 GTEx Artery Tibial AHI1 0.11 0.03 enet 16 0.09 1.8e-07 5.0 -5.8 8.4e-09 -0.71 0.04 0.96 FALSE
5 GTEx Brain Caudate basal ganglia AHI1 0.25 0.06 enet 24 0.15 5.4e-05 3.8 -5.6 2.2e-08 -0.67 0.03 0.80 FALSE
6 GTEx Brain Cerebellar Hemisphere AHI1 0.35 0.05 lasso 10 0.15 9.8e-05 4.0 -5.7 9.2e-09 -0.65 0.04 0.92 FALSE
7 GTEx Brain Cerebellar Hemisphere RP3-388E23.2 0.19 0.18 enet 17 0.26 2.4e-07 4.0 -5.4 6.9e-08 -0.67 0.04 0.82 FALSE
8 GTEx Brain Cortex AHI1 0.51 0.27 lasso 6 0.37 3.3e-11 5.2 -5.8 7.8e-09 -0.66 0.16 0.82 FALSE
9 GTEx Brain Cortex RP3-388E23.2 0.28 0.16 enet 13 0.19 5.8e-06 4.0 -6.0 1.6e-09 -0.72 0.12 0.78 FALSE
10 GTEx Brain Frontal Cortex BA9 AHI1 0.19 0.00 enet 14 0.05 1.5e-02 2.7 -7.3 2.0e-13 -0.52 0.05 0.36 TRUE
11 GTEx Breast Mammary Tissue AHI1 0.34 0.29 lasso 4 0.35 1.1e-18 4.0 -5.7 1.3e-08 -0.66 0.97 0.02 FALSE
12 GTEx Breast Mammary Tissue (Male) AHI1 0.19 0.06 lasso 2 0.14 3.2e-04 4.0 -5.7 1.2e-08 -0.64 0.04 0.46 FALSE
13 GTEx Cells EBV-transformed lymphocytes AHI1 0.38 0.24 enet 19 0.23 5.4e-08 5.4 -6.1 8.2e-10 -0.64 0.04 0.96 TRUE
14 GTEx Cells EBV-transformed lymphocytes RP3-388E23.2 0.26 0.05 lasso 6 0.02 7.1e-02 5.6 -5.7 1.2e-08 -0.66 0.03 0.87 FALSE
15 GTEx Cells Transformed fibroblasts AHI1 0.44 0.21 enet 22 0.32 4.4e-24 4.7 -5.6 2.6e-08 -0.69 0.37 0.63 FALSE
16 GTEx Cells Transformed fibroblasts RP3-388E23.2 0.13 0.13 lasso 5 0.15 3.5e-11 4.0 -5.5 3.7e-08 -0.62 0.88 0.11 FALSE
17 GTEx Esophagus Mucosa AHI1 0.30 0.24 lasso 8 0.32 4.6e-22 5.6 -6.2 6.3e-10 -0.69 0.03 0.97 FALSE
18 GTEx Nerve Tibial AHI1 0.41 0.36 lasso 5 0.41 5.8e-31 4.0 -5.4 6.7e-08 -0.61 0.98 0.02 FALSE
19 GTEx Skin Not Sun Exposed Suprapubic AHI1 0.41 0.31 lasso 7 0.40 9.1e-24 5.7 -6.3 2.2e-10 -0.72 0.02 0.98 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic RP3-388E23.2 0.14 0.03 enet 17 0.12 3.7e-07 5.4 -6.2 7.6e-10 -0.76 0.04 0.93 FALSE
21 GTEx Skin Sun Exposed Lower leg AHI1 0.33 0.22 enet 14 0.34 1.0e-28 4.0 -6.2 5.0e-10 -0.71 0.62 0.37 FALSE
22 GTEx Skin Sun Exposed Lower leg RP3-388E23.2 0.10 0.06 enet 6 0.04 3.1e-04 5.3 -5.8 5.0e-09 -0.72 0.06 0.92 FALSE
23 GTEx Small Intestine Terminal Ileum AHI1 0.51 0.01 enet 19 0.06 2.0e-02 5.7 -5.6 2.0e-08 -0.65 0.03 0.56 FALSE
24 GTEx Spleen AHI1 0.31 0.21 lasso 3 0.38 8.6e-11 5.4 -6.3 3.3e-10 -0.78 0.02 0.94 FALSE
25 GTEx Testis AHI1 0.37 0.32 enet 25 0.37 3.5e-17 5.6 -6.2 7.6e-10 -0.71 0.02 0.98 FALSE
26 GTEx Testis RP3-388E23.2 0.23 0.19 lasso 3 0.24 5.7e-11 4.0 -5.7 1.0e-08 -0.64 0.27 0.71 FALSE
27 METSIM Adipose AHI1 0.25 0.22 lasso 7 0.28 1.1e-42 5.4 -6.2 7.1e-10 -0.68 0.03 0.97 FALSE
28 NTR Blood AHI1 0.11 0.14 lasso 6 0.15 3.2e-47 5.6 -5.2 1.9e-07 -0.57 0.04 0.96 FALSE
29 ROSMAP Brain Pre-frontal Cortex AHI1 0.40 0.24 lasso 6 0.26 1.1e-33 4.0 -5.4 5.9e-08 -0.72 0.98 0.02 FALSE
30 YFS Blood AHI1 0.24 0.30 bslmm 414 0.33 1.4e-110 5.7 -6.0 2.6e-09 -0.68 0.02 0.98 FALSE
31 The Cancer Genome Atlas Breast Invasive Carcinoma AHI1 0.06 0.02 lasso 7 0.02 1.3e-04 5.7 -5.9 3.5e-09 -0.78 0.02 0.98 FALSE
32 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma AHI1 0.18 0.19 lasso 4 0.18 6.4e-20 5.7 -5.6 1.6e-08 -0.64 0.02 0.98 FALSE
33 The Cancer Genome Atlas Lung Squamous Cell Carcinoma AHI1 0.13 0.16 lasso 3 0.16 1.2e-17 5.7 -5.9 4.4e-09 -0.68 0.02 0.98 FALSE
34 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma AHI1 0.05 0.05 lasso 1 0.04 1.5e-03 5.4 -5.4 8.6e-08 -0.61 0.02 0.80 FALSE
35 The Cancer Genome Atlas Testicular Germ Cell Tumors AHI1 0.36 0.30 lasso 3 0.29 1.0e-10 5.4 -5.9 3.0e-09 -0.72 0.02 0.98 FALSE