Best TWAS P=7.57e-09 · Best GWAS P=1.06e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | SIK2 | 0.13 | 0.03 | lasso | 4 | 0.02 | 2.2e-02 | -6.1 | -5.8 | 7.6e-09 | 0.99 | 0.02 | 0.94 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SIK2 | 0.04 | 0.01 | blup | 35 | 0.01 | 6.7e-03 | -5.2 | -5.4 | 5.4e-08 | 0.88 | 0.03 | 0.84 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SIK2 | 0.05 | 0.06 | lasso | 1 | 0.05 | 2.6e-06 | -5.3 | -5.3 | 1.3e-07 | 0.91 | 0.07 | 0.93 | FALSE |