Best TWAS P=6.36e-08 · Best GWAS P=1.12e-07 conditioned to 4.37e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | CNTNAP1 | 0.07 | 0.08 | lasso | 5 | 0.06 | 1.9e-05 | -5.1 | -5.1 | 2.9e-07 | 0.40 | 0.04 | 0.90 | FALSE |
| 2 | GTEx | Esophagus Muscularis | NAGLU | 0.29 | 0.09 | lasso | 5 | 0.07 | 6.2e-05 | -4.4 | 5.2 | 2.4e-07 | -0.32 | 0.24 | 0.67 | FALSE |
| 3 | GTEx | Esophagus Muscularis | RP11-400F19.8 | 0.17 | 0.05 | lasso | 4 | 0.02 | 3.9e-02 | -4.4 | 5.4 | 6.4e-08 | -0.25 | 0.06 | 0.19 | TRUE |
| 4 | GTEx | Muscle Skeletal | TUBG2 | 0.12 | 0.09 | lasso | 8 | 0.10 | 1.1e-09 | -4.5 | 5.2 | 2.0e-07 | -0.33 | 0.27 | 0.72 | FALSE |