Best TWAS P=7.7e-09 · Best GWAS P=5.48e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | RP5-1042I8.7 | 0.17 | 0.00 | lasso | 11 | 0.03 | 0.01400 | 5.8 | 5.7 | 1.2e-08 | 0.99 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Artery Coronary | RP5-1042I8.7 | 0.11 | 0.07 | lasso | 2 | 0.04 | 0.01750 | 5.6 | 5.6 | 2.2e-08 | 0.98 | 0.02 | 0.90 | FALSE |
| 3 | GTEx | Liver | NOTCH2 | 0.14 | 0.13 | lasso | 2 | 0.10 | 0.00076 | 5.7 | -5.8 | 7.7e-09 | -0.98 | 0.02 | 0.86 | TRUE |