Best TWAS P=1.11e-09 · Best GWAS P=7.5e-13 conditioned to 0.00014
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | NAT2 | 0.06 | 0.00 | blup | 92 | 0.02 | 0.00980 | 3.4 | -5.2 | 1.7e-07 | -0.66 | 0.03 | 0.20 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NAT2 | 0.04 | 0.04 | lasso | 2 | 0.03 | 0.00024 | 6.1 | -6.1 | 1.1e-09 | -0.88 | 0.08 | 0.80 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | NAT2 | 0.03 | 0.01 | lasso | 2 | 0.01 | 0.02340 | 5.4 | -5.5 | 2.9e-08 | -0.66 | 0.06 | 0.54 | FALSE |