Best TWAS P=1.04e-12 · Best GWAS P=1.17e-13 conditioned to 0.296
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | DDX56 | 0.07 | 0.01 | lasso | 4 | 0.01 | 4.8e-02 | -5.4 | 5.6 | 2.1e-08 | 0.38 | 0.24 | 0.18 | FALSE |
| 2 | METSIM | Adipose | NPC1L1 | 0.11 | 0.12 | bslmm | 357 | 0.14 | 5.0e-20 | 7.4 | 7.1 | 1.0e-12 | 0.75 | 0.00 | 1.00 | TRUE |
| 3 | YFS | Blood | TMED4 | 0.13 | 0.12 | lasso | 13 | 0.15 | 1.3e-45 | -5.4 | 5.9 | 3.5e-09 | 0.53 | 0.99 | 0.01 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | DDX56 | 0.02 | 0.02 | enet | 5 | 0.01 | 2.5e-02 | -5.4 | 5.3 | 1.3e-07 | 0.27 | 0.12 | 0.02 | TRUE |