Best TWAS P=6.33e-08 · Best GWAS P=2.02e-08 conditioned to 0.116
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Lung | CSK | 0.09 | 0.06 | lasso | 3 | 0.05 | 1.4e-04 | 5.3 | 5.2 | 1.9e-07 | 0.82 | 0.04 | 0.95 | FALSE |
2 | GTEx | Vagina | COX5A | 0.38 | 0.02 | lasso | 7 | 0.02 | 9.3e-02 | 5.2 | -5.3 | 1.5e-07 | -0.72 | 0.05 | 0.47 | FALSE |
3 | YFS | Blood | CSK | 0.13 | 0.15 | lasso | 11 | 0.16 | 6.7e-51 | 5.4 | 5.4 | 6.3e-08 | 0.93 | 0.01 | 0.99 | TRUE |