Best TWAS P=2.51e-10 · Best GWAS P=6.11e-17 conditioned to 4.41e-08
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CDKN2B | 0.08 | 0.05 | lasso | 4 | 0.06 | 2.4e-07 | 6.2 | 6.3 | 2.5e-10 | 0.74 | 0.90 | 0.10 | TRUE |
2 | CommonMind | Brain Pre-frontal Cortex | CDKN2B-AS1 | 0.11 | 0.02 | blup | 501 | 0.03 | 1.7e-04 | 6.2 | 5.6 | 2.3e-08 | 0.67 | 0.05 | 0.95 | FALSE |