TWAS
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Medication: Aspirin
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chr9:21,303,958-22,819,407
Best TWAS P=2.51e-10 · Best GWAS P=6.11e-17 conditioned to 4.41e-08
21.4M
21.6M
21.8M
22M
22.2M
22.4M
22.6M
22.8M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
CDKN2B
0.08
0.05
lasso
4
0.06
2.4e-07
6.2
6.3
2.5e-10
0.74
0.90
0.10
TRUE
2
CommonMind
Brain Pre-frontal Cortex
CDKN2B-AS1
0.11
0.02
blup
501
0.03
1.7e-04
6.2
5.6
2.3e-08
0.67
0.05
0.95
FALSE