Best TWAS P=3.04e-09 · Best GWAS P=9.72e-10 conditioned to 0.0918
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | MLXIP | 0.20 | 0.18 | enet | 23 | 0.14 | 5.8e-07 | -6.0 | -5.9 | 3.0e-09 | 0.92 | 0.01 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | MLXIP | 0.06 | 0.04 | lasso | 7 | 0.02 | 2.7e-02 | -6.1 | -5.9 | 3.1e-09 | 0.99 | 0.02 | 0.94 | FALSE |
| 3 | The Cancer Genome Atlas | Rectum Adenocarcinoma | MLXIP | 0.18 | 0.14 | lasso | 4 | 0.13 | 5.1e-04 | -5.1 | -5.4 | 8.5e-08 | 0.92 | 0.02 | 0.88 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | MLXIP | 0.06 | 0.02 | blup | 68 | 0.04 | 1.2e-03 | -6.1 | -5.2 | 1.8e-07 | 0.89 | 0.02 | 0.89 | FALSE |