Best TWAS P=9.35e-12 · Best GWAS P=7.65e-12 conditioned to 0.0703
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | EIF2S2P3 | 0.09 | 0.04 | lasso | 6 | 0.04 | 1.1e-03 | -6.8 | -6.4 | 1.4e-10 | 0.81 | 0.01 | 0.95 | FALSE |
| 2 | GTEx | Prostate | EIF2S2P3 | 0.21 | 0.05 | lasso | 4 | 0.11 | 1.1e-03 | -6.8 | -5.6 | 1.8e-08 | 0.78 | 0.02 | 0.72 | FALSE |
| 3 | GTEx | Spleen | EIF2S2P3 | 0.32 | 0.04 | enet | 15 | 0.11 | 1.2e-03 | -4.4 | -5.7 | 1.4e-08 | 0.82 | 0.02 | 0.74 | FALSE |
| 4 | GTEx | Thyroid | EIF2S2P3 | 0.15 | 0.14 | lasso | 2 | 0.14 | 6.2e-11 | -6.8 | -6.8 | 9.4e-12 | 0.88 | 0.01 | 0.99 | TRUE |
| 5 | GTEx | Whole Blood | EIF2S2P3 | 0.10 | 0.02 | lasso | 6 | 0.05 | 2.2e-05 | -6.8 | -5.5 | 3.6e-08 | 0.76 | 0.01 | 0.99 | FALSE |