58 significantly associated models · 21 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 27467598 | 27949052 | 1 | 1 | 2.7e-07 | 1.3e-07 | 1.0e+00 | 100 | FNDC4 |
2 | 2 | 42767044 | 44157441 | 1 | 1 | 1.3e-08 | 1.4e-09 | 1.3e-02 | 83 | AC010883.5 |
3 | 3 | 22998569 | 23879862 | 1 | 1 | 1.2e-08 | 1.4e-10 | 2.1e-03 | 77 | UBE2E2 |
4 | 3 | 185112300 | 185786406 | 1 | 1 | 1.3e-14 | 1.7e-20 | 8.3e-09 | 61 | IGF2BP2 |
5 | 4 | 5575751 | 7002344 | 1 | 1 | 9.5e-12 | 6.9e-13 | 4.7e-03 | 84 | WFS1 |
6 | 4 | 52683607 | 53582065 | 1 | 1 | 1.1e-07 | 5.0e-07 | 8.5e-01 | 100 | LRRC66 |
7 | 4 | 103020804 | 104627833 | 2 | 1 | 1.6e-07 | 1.1e-06 | 1.7e-01 | 92 | UBE2D3 |
8 | 7 | 27623776 | 28468319 | 1 | 1 | 4.6e-12 | 2.0e-11 | 7.4e-02 | 93 | JAZF1 |
9 | 10 | 11693166 | 13569805 | 1 | 1 | 9.2e-09 | 1.2e-08 | 1.0e+00 | 100 | CAMK1D |
10 | 10 | 93730592 | 95128815 | 1 | 1 | 9.4e-12 | 7.7e-12 | 7.0e-02 | 93 | EIF2S2P3 |
11 | 10 | 113511441 | 115622375 | 2 | 1 | 4.8e-30 | 2.5e-100 | 3.1e-76 | 24 | TCF7L2 |
12 | 15 | 89680384 | 91135411 | 2 | 1 | 3.3e-08 | 5.1e-08 | 1.0e+00 | 100 | AP3S2 |
13 | 19 | 12352086 | 13750618 | 2 | 1 | 1.1e-07 | 1.4e-07 | 2.9e-01 | 96 | CALR |
14 | 19 | 45313715 | 46693262 | 1 | 1 | 8.3e-08 | 6.6e-05 | 2.2e-01 | 91 | PPM1N |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Artery Aorta | 1 | 0.034 | 1.5 |
GTEx | Artery Tibial | 0 | 0.000 | 1.5 |
GTEx | Brain Cerebellar Hemisphere | 1 | 0.067 | 1.5 |
GTEx | Brain Cerebellum | 1 | 0.050 | 1.5 |
GTEx | Brain Cortex | 1 | 0.097 | 1.5 |
GTEx | Breast Mammary Tissue | 0 | 0.000 | 1.5 |
GTEx | Cells Transformed fibroblasts | 2 | 0.048 | 1.5 |
GTEx | Esophagus Mucosa | 1 | 0.030 | 1.5 |
GTEx | Esophagus Muscularis | 1 | 0.031 | 1.5 |
GTEx | Lung | 1 | 0.035 | 1.5 |
GTEx | Nerve Tibial | 0 | 0.000 | 1.5 |
GTEx | Ovary | 0 | 0.000 | 1.5 |
GTEx | Pituitary | 0 | 0.000 | 1.5 |
GTEx | Skin Not Sun Exposed Suprapubic | 1 | 0.041 | 1.5 |
GTEx | Skin Sun Exposed Lower leg | 1 | 0.027 | 1.5 |
GTEx | Spleen | 1 | 0.071 | 1.5 |
GTEx | Testis | 1 | 0.032 | 1.5 |
GTEx | Thyroid | 3 | 0.075 | 1.5 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 1 | 0.090 | 1.5 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 2 | 0.068 | 1.5 |
GTEx | Adipose Subcutaneous | 0 | 0.000 | 1.4 |
GTEx | Adipose Visceral Omentum | 0 | 0.000 | 1.4 |
GTEx | Adrenal Gland | 0 | 0.000 | 1.4 |
GTEx | Brain Frontal Cortex BA9 | 0 | 0.000 | 1.4 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.4 |
GTEx | Breast Mammary Tissue (Male) | 0 | 0.000 | 1.4 |
GTEx | Breast Mammary Tissue (Female) | 0 | 0.000 | 1.4 |
GTEx | Cells EBV-transformed lymphocytes | 0 | 0.000 | 1.4 |
GTEx | Colon Sigmoid | 0 | 0.000 | 1.4 |
GTEx | Colon Transverse | 0 | 0.000 | 1.4 |
GTEx | Esophagus Gastroesophageal Junction | 0 | 0.000 | 1.4 |
GTEx | Heart Atrial Appendage | 1 | 0.063 | 1.4 |
GTEx | Heart Left Ventricle | 0 | 0.000 | 1.4 |
GTEx | Liver | 0 | 0.000 | 1.4 |
GTEx | Muscle Skeletal | 1 | 0.035 | 1.4 |
GTEx | Pancreas | 0 | 0.000 | 1.4 |
GTEx | Prostate | 1 | 0.120 | 1.4 |
GTEx | Stomach | 0 | 0.000 | 1.4 |
GTEx | Vagina | 0 | 0.000 | 1.4 |
GTEx | Whole Blood | 2 | 0.100 | 1.4 |
METSIM | Adipose | 1 | 0.022 | 1.4 |
NTR | Blood | 4 | 0.167 | 1.4 |
ROSMAP | Brain Pre-frontal Cortex | 2 | 0.046 | 1.4 |
YFS | Blood | 1 | 0.022 | 1.4 |
CommonMind | Brain Pre-frontal Cortex | 2 | 0.037 | 1.4 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 1 | 0.060 | 1.4 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 1 | 0.023 | 1.4 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 1 | 0.091 | 1.4 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 2 | 0.097 | 1.4 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 3 | 0.110 | 1.4 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 2 | 0.049 | 1.4 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 1 | 0.049 | 1.4 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 2 | 0.046 | 1.4 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 1 | 0.040 | 1.4 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 1 | 0.060 | 1.4 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 1 | 0.022 | 1.4 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 1 | 0.145 | 1.4 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 1 | 0.094 | 1.4 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Thyroid Carcinoma | 3 | 0.058 | 1.4 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 1 | 0.197 | 1.4 |
GTEx | Artery Coronary | 0 | 0.000 | 1.3 |
GTEx | Brain Caudate basal ganglia | 0 | 0.000 | 1.3 |
GTEx | Brain Hypothalamus | 0 | 0.000 | 1.3 |
GTEx | Brain Nucleus accumbens basal ganglia | 0 | 0.000 | 1.3 |
GTEx | Brain Putamen basal ganglia | 0 | 0.000 | 1.3 |
GTEx | Small Intestine Terminal Ileum | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Esophageal Carcinoma | 1 | 0.146 | 1.3 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 1 | 0.059 | 1.3 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 0 | 0.000 | 1.3 |
GTEx | Uterus | 0 | 0.000 | 1.2 |