Hub : Traits :

Medication: Metformin

58 significantly associated models · 21 unique genes.

Significant Loci

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	2	27467598	27949052	1	1	2.7e-07	1.3e-07	1.0e+00	100	FNDC4
2	2	42767044	44157441	1	1	1.3e-08	1.4e-09	1.3e-02	83	AC010883.5
3	3	22998569	23879862	1	1	1.2e-08	1.4e-10	2.1e-03	77	UBE2E2
4	3	185112300	185786406	1	1	1.3e-14	1.7e-20	8.3e-09	61	IGF2BP2
5	4	5575751	7002344	1	1	9.5e-12	6.9e-13	4.7e-03	84	WFS1
6	4	52683607	53582065	1	1	1.1e-07	5.0e-07	8.5e-01	100	LRRC66
7	4	103020804	104627833	2	1	1.6e-07	1.1e-06	1.7e-01	92	UBE2D3
8	7	27623776	28468319	1	1	4.6e-12	2.0e-11	7.4e-02	93	JAZF1
9	10	11693166	13569805	1	1	9.2e-09	1.2e-08	1.0e+00	100	CAMK1D
10	10	93730592	95128815	1	1	9.4e-12	7.7e-12	7.0e-02	93	EIF2S2P3
11	10	113511441	115622375	2	1	4.8e-30	2.5e-100	3.1e-76	24	TCF7L2
12	15	89680384	91135411	2	1	3.3e-08	5.1e-08	1.0e+00	100	AP3S2
13	19	12352086	13750618	2	1	1.1e-07	1.4e-07	2.9e-01	96	CALR
14	19	45313715	46693262	1	1	8.3e-08	6.6e-05	2.2e-01	91	PPM1N

Pleiotropic Associations

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr	corr P	genes
Bipolar Disorder (2018)	1.54	1	0	0.0	0.00	1.0e+00	FNDC4
Bipolar Disorder or Schizophrenia	1.28	1	0	0.0	0.00	1.0e+00	UBE2D3
Depressed Affect (Nagel 2018)	1.20	1	0	0.0	0.00	1.0e+00	AC010883.5
Neuroticism (Nagel 2018)	1.54	1	0	0.0	0.00	1.0e+00	AC010883.5
Schizophrenia (2018)	1.08	1	0	0.0	0.00	1.0e+00	UBE2D3
Schizophrenia vs Biploar Disorder	1.51	1	0	0.0	0.00	1.0e+00	FNDC4
Crohns Disease (2017)	4.13	4	2	4.4	-0.42	5.8e-01	AC010883.5 FNDC4 JAZF1 PPM1N
Irritable Bowel Disease (IBD)	3.56	3	2	4.4	0.00	1.0e+00	AC010883.5 EIF2S2P3 FNDC4
Ulcerative Colitis (UC)	2.50	2	0	0.0	0.00	1.0e+00	AC010883.5 UBE2D3
Breast Cancer	3.24	2	1	2.2	0.00	1.0e+00	CALR TCF7L2
Body Mass Index (BMI) (2010)	2.06	1	0	0.0	0.00	1.0e+00	TCF7L2
Crohns Disease (2012)	2.61	2	0	0.0	0.00	1.0e+00	AC010883.5 FNDC4
Fasting Glucose	9.82	1	1	2.2	0.00	1.0e+00	FNDC4
LDL Cholesterol	1.19	1	0	0.0	0.00	1.0e+00	FNDC4
Primary Biliary Cirrhosis	2.66	2	0	0.0	0.00	1.0e+00	FNDC4 UBE2D3
Schizophrenia (2014)	1.20	1	0	0.0	0.00	1.0e+00	UBE2D3
Triglycerides	27.65	1	1	2.2	0.00	1.0e+00	FNDC4
Type 2 Diabetes (T2D) (2012)	16.54	8	4	8.9	0.97	8.2e-05	AC010883.5 EIF2S2P3 IGF2BP2 JAZF1 TCF7L2 UBE2D3 UBE2E2 WFS1
Ulcerative Colitis	2.37	1	0	0.0	0.00	1.0e+00	AC010883.5
Blood Eosinophil Count	2.15	3	3	6.7	0.00	1.0e+00	AC010883.5 EIF2S2P3 JAZF1
Blood Platelet Count	7.43	7	4	8.9	-0.19	6.8e-01	AC010883.5 AP3S2 FNDC4 IGF2BP2 LRRC66 PPM1N UBE2E2
Blood Red Count	2.96	5	3	6.7	0.91	2.9e-02	CALR EIF2S2P3 FNDC4 IGF2BP2 PPM1N
Blood White Count	2.86	2	1	2.2	0.00	1.0e+00	FNDC4 LRRC66
Heel T-Score	1.59	4	2	4.4	-0.03	9.7e-01	AC010883.5 CALR IGF2BP2 JAZF1
BMI	2.18	6	3	6.7	-0.46	3.6e-01	FNDC4 JAZF1 LRRC66 PPM1N TCF7L2 UBE2D3
Height	3.66	8	5	11.1	0.03	9.5e-01	AC010883.5 AP3S2 CALR FNDC4 JAZF1 LRRC66 UBE2D3 UBE2E2
Waist Hip Ratio (WHR)	4.64	5	4	8.9	0.89	4.2e-02	AC010883.5 EIF2S2P3 IGF2BP2 JAZF1 TCF7L2
Systolic Blood Pressure	2.18	5	2	4.4	0.68	2.1e-01	CAMK1D FNDC4 JAZF1 LRRC66 TCF7L2
Allergy or Eczema	2.55	4	0	0.0	-0.31	6.9e-01	AC010883.5 FNDC4 JAZF1 UBE2D3
Cardiovascular Disease	3.56	5	2	4.4	0.45	4.5e-01	CAMK1D FNDC4 IGF2BP2 PPM1N UBE2D3
Hypothyroidism (self reported)	1.42	2	0	0.0	0.00	1.0e+00	AC010883.5 IGF2BP2
Respiratory disease	2.30	2	1	2.2	0.00	1.0e+00	EIF2S2P3 JAZF1
Type 2 Diabetes (T2D) (2018)	36.44	13	11	24.4	1.00	1.9e-12	AC010883.5 AP3S2 CALR CAMK1D EIF2S2P3 FNDC4 IGF2BP2 JAZF1 LRRC66 PPM1N TCF7L2 UBE2E2 WFS1
Lung FEV1/FVC ratio	3.96	4	3	6.7	-0.66	3.4e-01	AC010883.5 CAMK1D IGF2BP2 PPM1N
Lung FVC	2.60	4	2	4.4	-0.96	3.7e-02	CAMK1D FNDC4 IGF2BP2 JAZF1
Chronotype (morning person)	2.18	1	1	2.2	0.00	1.0e+00	PPM1N
Hair Pigment	0.67	3	1	2.2	0.00	1.0e+00	AC010883.5 FNDC4 JAZF1
Tanning	0.80	2	2	4.4	0.00	1.0e+00	FNDC4 JAZF1
Hand grip strength (left)	1.25	2	0	0.0	0.00	1.0e+00	AC010883.5 FNDC4
Number of treatments/medications taken	4.16	3	1	2.2	0.00	1.0e+00	FNDC4 LRRC66 UBE2D3
Sensitivity / hurt feelings	1.07	1	0	0.0	0.00	1.0e+00	UBE2D3
Relative age of first facial hair	2.07	1	1	2.2	0.00	1.0e+00	FNDC4
Systolic blood pressure, automated reading	1.95	2	1	2.2	0.00	1.0e+00	CAMK1D LRRC66
Eye problems/disorders: Diabetes related eye disease	6.46	2	0	0.0	0.00	1.0e+00	IGF2BP2 TCF7L2
Diabetes (father)	18.35	8	4	8.9	0.99	5.2e-07	AC010883.5 AP3S2 EIF2S2P3 FNDC4 IGF2BP2 JAZF1 TCF7L2 WFS1
Diabetes (mother)	16.63	9	3	6.7	0.99	1.2e-07	AC010883.5 CALR CAMK1D EIF2S2P3 FNDC4 IGF2BP2 TCF7L2 UBE2E2 WFS1
Impedance of leg (right)	3.73	3	3	6.7	0.00	1.0e+00	AC010883.5 FNDC4 JAZF1
Leg fat-free mass (left)	2.68	3	1	2.2	0.00	1.0e+00	FNDC4 LRRC66 WFS1
Trunk fat percentage	0.99	1	0	0.0	0.00	1.0e+00	LRRC66
Hand grip strength (right)	1.14	1	0	0.0	0.00	1.0e+00	FNDC4
Maternal smoking around birth	1.01	1	0	0.0	0.00	1.0e+00	AC010883.5
Fed-up feelings	1.39	1	0	0.0	0.00	1.0e+00	AC010883.5
Taking other prescription medications	2.03	1	0	0.0	0.00	1.0e+00	UBE2D3
Heel bone mineral density (BMD) T-score, automated (left)	1.77	2	0	0.0	0.00	1.0e+00	AC010883.5 UBE2D3
High blood pressure	2.39	3	1	2.2	0.00	1.0e+00	CAMK1D IGF2BP2 UBE2D3
Hayfever, allergic rhinitis or eczema	2.24	3	0	0.0	0.00	1.0e+00	AC010883.5 FNDC4 JAZF1
Sitting height	2.03	4	2	4.4	0.19	8.1e-01	FNDC4 JAZF1 UBE2D3 UBE2E2
Body mass index (BMI)	1.97	4	1	2.2	-0.59	4.1e-01	FNDC4 JAZF1 LRRC66 TCF7L2
Impedance of leg (left)	3.96	3	3	6.7	0.00	1.0e+00	AC010883.5 FNDC4 JAZF1
Leg predicted mass (left)	2.70	3	1	2.2	0.00	1.0e+00	FNDC4 LRRC66 WFS1
Trunk fat mass	1.38	3	0	0.0	0.00	1.0e+00	JAZF1 LRRC66 TCF7L2
Waist circumference	1.42	2	0	0.0	0.00	1.0e+00	FNDC4 TCF7L2
Forced vital capacity (FVC)	1.59	3	0	0.0	0.00	1.0e+00	CALR CAMK1D IGF2BP2
Heel bone mineral density (BMD) T-score, automated (right)	1.39	1	0	0.0	0.00	1.0e+00	AC010883.5
Heart attack	2.08	1	0	0.0	0.00	1.0e+00	AC010883.5
Allergy	2.38	3	0	0.0	0.00	1.0e+00	AC010883.5 JAZF1 UBE2D3
Diabetes (self-reported)	29.14	14	8	17.8	0.99	1.5e-11	AC010883.5 AP3S2 CALR CAMK1D EIF2S2P3 FNDC4 IGF2BP2 JAZF1 LRRC66 PPM1N TCF7L2 UBE2D3 UBE2E2 WFS1
Medication: Ramipril	3.95	1	0	0.0	0.00	1.0e+00	UBE2D3
Medication: Simvastatin	5.75	4	1	2.2	0.45	5.5e-01	FNDC4 LRRC66 PPM1N TCF7L2
Illnesses of siblings	2.48	1	0	0.0	0.00	1.0e+00	IGF2BP2
Neuroticism score	1.30	1	0	0.0	0.00	1.0e+00	AC010883.5
Weight	2.23	4	2	4.4	0.14	8.6e-01	FNDC4 JAZF1 LRRC66 TCF7L2
Impedance of arm (right)	4.07	4	3	6.7	0.10	9.0e-01	FNDC4 JAZF1 TCF7L2 UBE2D3
Arm fat percentage (right)	1.05	1	0	0.0	0.00	1.0e+00	TCF7L2
Trunk fat-free mass	3.79	4	2	4.4	-0.63	3.7e-01	FNDC4 JAZF1 LRRC66 WFS1
Hip circumference	2.20	3	2	4.4	0.00	1.0e+00	FNDC4 LRRC66 TCF7L2
Alcohol intake versus 10 years previously	3.62	1	1	2.2	0.00	1.0e+00	FNDC4
Father's age at death	1.61	1	0	0.0	0.00	1.0e+00	LRRC66
Worrier / anxious feelings	1.67	1	0	0.0	0.00	1.0e+00	TCF7L2
Hair/balding pattern: Pattern 3	1.40	1	0	0.0	0.00	1.0e+00	UBE2E2
Number of live births	1.32	1	0	0.0	0.00	1.0e+00	UBE2D3
Forced expiratory volume in 1-second (FEV1)	2.65	3	1	2.2	0.00	1.0e+00	CALR CAMK1D IGF2BP2
Pulse rate	3.84	1	1	2.2	0.00	1.0e+00	FNDC4
Mouth/teeth dental problems: Dentures	1.47	1	0	0.0	0.00	1.0e+00	FNDC4
Asthma	2.28	2	0	0.0	0.00	1.0e+00	EIF2S2P3 JAZF1
Medication: Cholesterol lowering	7.60	3	1	2.2	0.00	1.0e+00	FNDC4 IGF2BP2 TCF7L2
Illnesses of mother	2.32	1	0	0.0	0.00	1.0e+00	IGF2BP2
Forced expiratory volume in 1-second (FEV1), Best measure	2.52	2	1	2.2	0.00	1.0e+00	CAMK1D IGF2BP2
Impedance of arm (left)	4.67	6	3	6.7	-0.11	8.4e-01	AC010883.5 CALR FNDC4 JAZF1 TCF7L2 UBE2D3
Arm fat mass (right)	1.50	3	0	0.0	0.00	1.0e+00	FNDC4 LRRC66 TCF7L2
Trunk predicted mass	3.80	3	2	4.4	0.00	1.0e+00	FNDC4 JAZF1 LRRC66
Standing height	3.49	5	2	4.4	0.61	2.7e-01	CALR FNDC4 JAZF1 LRRC66 UBE2E2
Hair/balding pattern: Pattern 4	1.37	1	0	0.0	0.00	1.0e+00	AC010883.5
Birth weight of first child	1.67	1	0	0.0	0.00	1.0e+00	IGF2BP2
Peak expiratory flow (PEF)	3.37	3	2	4.4	0.00	1.0e+00	AC010883.5 CAMK1D IGF2BP2
Headache pain in last month	2.02	1	0	0.0	0.00	1.0e+00	UBE2D3
Medication for cholesterol, blood pressure or diabetes	5.86	5	0	0.0	-0.62	2.6e-01	CAMK1D FNDC4 IGF2BP2 PPM1N UBE2D3
Gout (self-reported)	6.84	1	1	2.2	0.00	1.0e+00	FNDC4
Hypothyroidism/myxoedema (self-reported)	1.47	1	0	0.0	0.00	1.0e+00	IGF2BP2
Birth weight	2.97	1	1	2.2	0.00	1.0e+00	EIF2S2P3
High blood pressure (siblings)	2.10	1	0	0.0	0.00	1.0e+00	FNDC4
Forced vital capacity (FVC), Best measure	1.48	2	0	0.0	0.00	1.0e+00	CAMK1D JAZF1
Body fat percentage	1.11	1	0	0.0	0.00	1.0e+00	TCF7L2
Leg fat percentage (right)	1.41	1	1	2.2	0.00	1.0e+00	TCF7L2
Arm fat-free mass (right)	3.64	3	1	2.2	0.00	1.0e+00	FNDC4 JAZF1 LRRC66
Comparative body size at age 10	1.44	1	0	0.0	0.00	1.0e+00	FNDC4
Age at first live birth	1.39	1	0	0.0	0.00	1.0e+00	EIF2S2P3
Medication for pain relief, constipation, heartburn	2.70	1	0	0.0	0.00	1.0e+00	UBE2D3
Medication: Blood pressure	3.45	3	1	2.2	0.00	1.0e+00	CAMK1D PPM1N UBE2D3
Migraine (self-reported)	2.05	1	0	0.0	0.00	1.0e+00	UBE2D3
Medication: Allopurinol	6.15	1	1	2.2	0.00	1.0e+00	FNDC4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.91	1	0	0.0	0.00	1.0e+00	TCF7L2
Whole body fat mass	1.48	3	0	0.0	0.00	1.0e+00	FNDC4 LRRC66 TCF7L2
Leg fat mass (right)	1.72	3	1	2.2	0.00	1.0e+00	FNDC4 LRRC66 TCF7L2
Arm predicted mass (right)	3.62	3	1	2.2	0.00	1.0e+00	FNDC4 JAZF1 LRRC66
Pulse rate, automated reading	4.93	4	2	4.4	0.32	6.8e-01	AC010883.5 FNDC4 JAZF1 WFS1
Alcohol intake frequency.	7.04	2	1	2.2	0.00	1.0e+00	FNDC4 LRRC66
Comparative height size at age 10	3.96	6	3	6.7	0.35	4.9e-01	AC010883.5 EIF2S2P3 FNDC4 JAZF1 LRRC66 UBE2E2
Overall health rating	1.95	1	0	0.0	0.00	1.0e+00	UBE2D3
Age at last live birth	1.34	1	0	0.0	0.00	1.0e+00	EIF2S2P3
Medication: Aspirin	4.82	2	0	0.0	0.00	1.0e+00	IGF2BP2 LRRC66
Hypertension (Self-reported)	2.43	3	1	2.2	0.00	1.0e+00	CAMK1D IGF2BP2 UBE2D3
Illnesses of father: Heart disease	1.80	1	0	0.0	0.00	1.0e+00	FNDC4
Illnesses of siblings: Diabetes	10.76	6	3	6.7	0.99	2.9e-04	AC010883.5 CAMK1D EIF2S2P3 IGF2BP2 TCF7L2 WFS1
Smoking status: Previous	1.25	1	0	0.0	0.00	1.0e+00	CALR
Forced expiratory volume in 1-second (FEV1), predicted	3.03	1	1	2.2	0.00	1.0e+00	JAZF1
Whole body fat-free mass	3.45	4	1	2.2	-0.69	3.1e-01	FNDC4 JAZF1 LRRC66 WFS1
Leg fat-free mass (right)	2.64	3	1	2.2	0.00	1.0e+00	FNDC4 LRRC66 WFS1
Arm fat percentage (left)	0.98	1	0	0.0	0.00	1.0e+00	TCF7L2
Mood swings	1.26	1	0	0.0	0.00	1.0e+00	AC010883.5
Long-standing illness, disability or infirmity	2.84	1	0	0.0	0.00	1.0e+00	IGF2BP2
Diabetes diagnosed by doctor	32.81	14	10	22.2	0.99	8.8e-13	AC010883.5 AP3S2 CALR CAMK1D EIF2S2P3 FNDC4 IGF2BP2 JAZF1 LRRC66 PPM1N TCF7L2 UBE2D3 UBE2E2 WFS1
Qualifications: nursing, teaching	1.03	1	0	0.0	0.00	1.0e+00	TCF7L2
Medication for cholesterol	3.42	2	1	2.2	0.00	1.0e+00	FNDC4 UBE2D3
Breast cancer (self-reported)	1.52	1	0	0.0	0.00	1.0e+00	TCF7L2
Asthma (self-reported)	2.14	2	0	0.0	0.00	1.0e+00	EIF2S2P3 JAZF1
Osteoporosis (self-reported)	1.15	1	0	0.0	0.00	1.0e+00	FNDC4
Medication: Aspirin	5.06	2	0	0.0	0.00	1.0e+00	IGF2BP2 LRRC66
Medication: Gliclazide	14.50	6	2	4.4	1.00	2.7e-06	FNDC4 IGF2BP2 JAZF1 TCF7L2 UBE2E2 WFS1
Illnesses of father: None of the above (group 1)	2.75	1	0	0.0	0.00	1.0e+00	CAMK1D
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.73	3	1	2.2	0.00	1.0e+00	CAMK1D IGF2BP2 JAZF1
Whole body water mass	3.47	4	1	2.2	-0.69	3.1e-01	FNDC4 JAZF1 LRRC66 WFS1
Leg predicted mass (right)	2.63	3	1	2.2	0.00	1.0e+00	FNDC4 LRRC66 WFS1
Arm fat mass (left)	1.39	3	0	0.0	0.00	1.0e+00	FNDC4 LRRC66 TCF7L2
Number of self-reported non-cancer illnesses	4.27	4	1	2.2	0.49	5.1e-01	FNDC4 IGF2BP2 JAZF1 UBE2D3
Guilty feelings	1.26	1	0	0.0	0.00	1.0e+00	AP3S2
Medication: Blood pressure	2.00	1	0	0.0	0.00	1.0e+00	UBE2D3
High cholesterol (Self-reported)	8.16	1	1	2.2	0.00	1.0e+00	FNDC4
Medication: Paracetamol	2.43	1	0	0.0	0.00	1.0e+00	UBE2D3
Medication: Atorvastatin	6.77	2	1	2.2	0.00	1.0e+00	FNDC4 TCF7L2
Basal metabolic rate	3.14	5	1	2.2	0.26	6.8e-01	FNDC4 JAZF1 LRRC66 TCF7L2 WFS1
Leg fat percentage (left)	1.43	1	1	2.2	0.00	1.0e+00	TCF7L2
Arm fat-free mass (left)	3.53	5	1	2.2	0.25	6.9e-01	FNDC4 JAZF1 LRRC66 TCF7L2 WFS1
Irritability	1.74	1	0	0.0	0.00	1.0e+00	AC010883.5
Diastolic blood pressure, automated reading	1.17	2	0	0.0	0.00	1.0e+00	TCF7L2 UBE2D3
Vascular/heart problems diagnosed by doctor	2.82	3	1	2.2	0.00	1.0e+00	IGF2BP2 PPM1N UBE2D3
Cholesterol lowering medication	5.58	3	1	2.2	0.00	1.0e+00	FNDC4 LRRC66 TCF7L2
Heart attack/myocardial infarction (self-reported)	1.95	1	0	0.0	0.00	1.0e+00	AC010883.5
Impedance of whole body	4.61	6	4	8.9	-0.11	8.3e-01	AC010883.5 FNDC4 JAZF1 TCF7L2 UBE2D3 WFS1
Leg fat mass (left)	1.79	3	1	2.2	0.00	1.0e+00	FNDC4 LRRC66 TCF7L2
Arm predicted mass (left)	3.45	3	1	2.2	0.00	1.0e+00	FNDC4 JAZF1 LRRC66

Associations by panel

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Adipose Subcutaneous	0	0.000	1.4
GTEx	Adipose Visceral Omentum	0	0.000	1.4
GTEx	Adrenal Gland	0	0.000	1.4
GTEx	Artery Aorta	1	0.034	1.5
GTEx	Artery Coronary	0	0.000	1.3
GTEx	Artery Tibial	0	0.000	1.5
GTEx	Brain Caudate basal ganglia	0	0.000	1.3
GTEx	Brain Cerebellar Hemisphere	1	0.067	1.5
GTEx	Brain Cerebellum	1	0.050	1.5
GTEx	Brain Cortex	1	0.097	1.5
GTEx	Brain Frontal Cortex BA9	0	0.000	1.4
GTEx	Brain Hippocampus	0	0.000	1.4
GTEx	Brain Hypothalamus	0	0.000	1.3
GTEx	Brain Nucleus accumbens basal ganglia	0	0.000	1.3
GTEx	Brain Putamen basal ganglia	0	0.000	1.3
GTEx	Breast Mammary Tissue	0	0.000	1.5
GTEx	Breast Mammary Tissue (Male)	0	0.000	1.4
GTEx	Breast Mammary Tissue (Female)	0	0.000	1.4
GTEx	Cells EBV-transformed lymphocytes	0	0.000	1.4
GTEx	Cells Transformed fibroblasts	2	0.048	1.5
GTEx	Colon Sigmoid	0	0.000	1.4
GTEx	Colon Transverse	0	0.000	1.4
GTEx	Esophagus Gastroesophageal Junction	0	0.000	1.4
GTEx	Esophagus Mucosa	1	0.030	1.5
GTEx	Esophagus Muscularis	1	0.031	1.5
GTEx	Heart Atrial Appendage	1	0.063	1.4
GTEx	Heart Left Ventricle	0	0.000	1.4
GTEx	Liver	0	0.000	1.4
GTEx	Lung	1	0.035	1.5
GTEx	Muscle Skeletal	1	0.035	1.4
GTEx	Nerve Tibial	0	0.000	1.5
GTEx	Ovary	0	0.000	1.5
GTEx	Pancreas	0	0.000	1.4
GTEx	Pituitary	0	0.000	1.5
GTEx	Prostate	1	0.120	1.4
GTEx	Skin Not Sun Exposed Suprapubic	1	0.041	1.5
GTEx	Skin Sun Exposed Lower leg	1	0.027	1.5
GTEx	Small Intestine Terminal Ileum	0	0.000	1.3
GTEx	Spleen	1	0.071	1.5
GTEx	Stomach	0	0.000	1.4
GTEx	Testis	1	0.032	1.5
GTEx	Thyroid	3	0.075	1.5
GTEx	Uterus	0	0.000	1.2
GTEx	Vagina	0	0.000	1.4
GTEx	Whole Blood	2	0.100	1.4
METSIM	Adipose	1	0.022	1.4
NTR	Blood	4	0.167	1.4
ROSMAP	Brain Pre-frontal Cortex	2	0.046	1.4
YFS	Blood	1	0.022	1.4
CommonMind	Brain Pre-frontal Cortex	2	0.037	1.4
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	1	0.060	1.4
The Cancer Genome Atlas	Breast Invasive Carcinoma	1	0.023	1.4
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	1	0.091	1.4
The Cancer Genome Atlas	Colon Adenocarcinoma	2	0.097	1.4
The Cancer Genome Atlas	Esophageal Carcinoma	1	0.146	1.3
The Cancer Genome Atlas	Glioblastoma Multiforme	0	0.000	1.4
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	3	0.110	1.4
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	2	0.049	1.4
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	1	0.049	1.4
The Cancer Genome Atlas	Brain Lower Grade Glioma	2	0.046	1.4
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	1	0.090	1.5
The Cancer Genome Atlas	Lung Adenocarcinoma	2	0.068	1.5
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	1	0.040	1.4
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	0	0.000	1.4
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	1	0.060	1.4
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	0	0.000	1.3
The Cancer Genome Atlas	Prostate Adenocarcinoma	1	0.022	1.4
The Cancer Genome Atlas	Rectum Adenocarcinoma	1	0.145	1.4
The Cancer Genome Atlas	Soft Tissue Sarcoma	1	0.094	1.4
The Cancer Genome Atlas	Skin Cutaneous Melanoma	0	0.000	1.4
The Cancer Genome Atlas	Stomach Adenocarcinoma	1	0.059	1.3
The Cancer Genome Atlas	Testicular Germ Cell Tumors	0	0.000	1.3
The Cancer Genome Atlas	Thyroid Carcinoma	3	0.058	1.4
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	1	0.197	1.4