[Hub]/) : Traits : Medication: Metformin : ← →

chr4:5,575,751-7,002,344

Best TWAS P=9.47e-12 · Best GWAS P=6.92e-13 conditioned to 0.00471

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex WFS1 0.10 0.03 lasso 2 0.02 4.8e-04 -6.9 6.6 3.8e-11 -0.86 0.02 0.97 FALSE
2 GTEx Brain Cerebellar Hemisphere WFS1 0.72 0.49 lasso 13 0.47 1.3e-13 -6.2 6.4 1.2e-10 -0.87 0.05 0.95 FALSE
3 GTEx Brain Cerebellum WFS1 0.44 0.26 lasso 10 0.27 9.8e-09 -6.2 6.3 3.2e-10 -0.86 0.04 0.96 FALSE
4 GTEx Cells Transformed fibroblasts WFS1 0.22 0.04 enet 25 0.08 2.6e-06 -6.5 6.8 9.5e-12 -0.81 0.05 0.94 TRUE
5 GTEx Muscle Skeletal WFS1 0.13 0.11 lasso 5 0.09 3.9e-09 -6.5 6.5 1.1e-10 -0.85 0.22 0.78 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic WFS1 0.35 0.25 lasso 7 0.28 7.6e-16 -6.5 6.2 6.5e-10 -0.80 0.10 0.90 FALSE
7 GTEx Skin Sun Exposed Lower leg WFS1 0.29 0.29 lasso 3 0.29 2.6e-24 -6.2 6.0 1.8e-09 -0.87 0.44 0.56 FALSE
8 GTEx Thyroid WFS1 0.19 0.12 lasso 4 0.10 2.9e-08 -6.2 6.0 1.4e-09 -0.87 0.20 0.80 FALSE
9 METSIM Adipose WFS1 0.06 0.01 enet 14 0.02 1.5e-04 -7.0 6.4 1.9e-10 -0.72 0.02 0.96 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma WFS1 0.07 0.10 lasso 3 0.10 2.6e-11 -6.8 6.8 1.3e-11 -0.86 0.04 0.96 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma WFS1 0.04 0.01 blup 76 0.01 1.6e-02 -6.2 6.2 5.7e-10 -0.84 0.02 0.96 FALSE