Best TWAS P=1.25e-14 · Best GWAS P=3.6e-24 conditioned to 2.93e-12
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | RP5-1024G6.5 | 0.17 | 0.00 | enet | 12 | 0.00 | 0.4890 | -2.66 | -5.5 | 3.0e-08 | -0.03 | 0.06 | 0.08 | TRUE |
2 | GTEx | Pituitary | CPT2 | 0.32 | -0.01 | lasso | 10 | 0.01 | 0.1540 | -3.95 | 5.2 | 2.1e-07 | 0.12 | 0.06 | 0.05 | FALSE |
3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | GLIS1 | 0.10 | 0.05 | enet | 9 | 0.04 | 0.0022 | 8.14 | 7.7 | 1.3e-14 | 0.50 | 0.15 | 0.38 | TRUE |
4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | PODN | 0.22 | 0.01 | blup | 94 | 0.06 | 0.0033 | 0.99 | -5.2 | 1.9e-07 | -0.01 | 0.01 | 0.16 | TRUE |