Best TWAS P=1.42e-08 · Best GWAS P=9.2e-07 conditioned to 0.000405
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | RP11-514P8.8 | 0.15 | 0.00 | enet | 22 | 0.06 | 3.1e-05 | -2.6 | 5.4 | 7.0e-08 | -0.45 | 0.04 | 0.31 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | POLR2J3 | 0.17 | 0.06 | enet | 15 | 0.08 | 5.1e-07 | 3.6 | 5.7 | 1.4e-08 | -0.26 | 0.31 | 0.14 | TRUE |
| 3 | GTEx | Whole Blood | POLR2J3 | 0.07 | 0.02 | enet | 20 | 0.03 | 1.5e-03 | -4.3 | 5.2 | 2.3e-07 | -0.70 | 0.05 | 0.74 | FALSE |