Best TWAS P=3.71e-13 · Best GWAS P=2.34e-24 conditioned to 4.37e-17
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | TRPS1 | 0.05 | 0.02 | enet | 19 | 0.02 | 0.0024 | 9.7 | -7.3 | 3.7e-13 | 0.07 | 0.15 | 0.65 | TRUE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TRPS1 | 0.04 | 0.03 | blup | 102 | 0.01 | 0.0096 | 3.9 | -7.1 | 9.4e-13 | 0.48 | 0.06 | 0.29 | TRUE |