Best TWAS P=9.05e-10 · Best GWAS P=5.12e-08 conditioned to 0.00335
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | OTUD1 | 0.07 | 0.04 | enet | 12 | 0.03 | 0.00522 | 5.4 | 6.1 | 9.0e-10 | 0.46 | 0.03 | 0.86 | TRUE |
2 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | OTUD1 | 0.11 | 0.07 | lasso | 2 | 0.06 | 0.00057 | 5.1 | -5.2 | 2.5e-07 | -0.80 | 0.01 | 0.87 | FALSE |