Best TWAS P=5.04e-53 · Best GWAS P=9.32e-48 conditioned to 0.000398
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | COL11A1 | 0.01 | 0.01 | blup | 156 | 0.01 | 0.0027 | -10.9 | -15.3 | 5.0e-53 | 0.81 | 0.02 | 0.84 | TRUE |
| 2 | The Cancer Genome Atlas | Esophageal Carcinoma | COL11A1 | 0.23 | 0.04 | lasso | 3 | 0.04 | 0.0172 | 6.2 | -7.8 | 9.3e-15 | 0.55 | 0.06 | 0.36 | FALSE |