Best TWAS P=2.01e-11 · Best GWAS P=9.64e-09 conditioned to 0.0229
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SAV1 | 0.09 | 0.03 | blup | 478 | 0.07 | 2.1e-08 | -4.2 | -5.4 | 7.4e-08 | -0.49 | 0.30 | 0.69 | FALSE |
| 2 | GTEx | Brain Cerebellar Hemisphere | SAV1 | 0.19 | 0.06 | lasso | 7 | 0.02 | 1.3e-01 | -4.4 | -5.7 | 1.5e-08 | -0.39 | 0.07 | 0.51 | FALSE |
| 3 | GTEx | Liver | RP11-248J18.2 | 0.32 | -0.01 | enet | 5 | -0.01 | 7.0e-01 | 5.4 | 5.6 | 2.6e-08 | 0.95 | 0.03 | 0.64 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SAV1 | 0.07 | 0.02 | enet | 8 | 0.04 | 2.3e-05 | 5.6 | -6.7 | 2.0e-11 | -0.58 | 0.01 | 0.98 | TRUE |