TWAS hub - SAV1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0910	0.0280	1.3e-06	0.031	0.065	0.051	0.063	0.037	1.1e-04	2.1e-08	6.7e-07	3.4e-08	2.2e-05
2	GTEx	Brain Cerebellar Hemisphere	0.1920	0.0800	4.8e-03	0.060	NA	-0.011	NA	0.015	1.2e-02	NA	9.1e-01	NA	1.3e-01
3	GTEx	Cells Transformed fibroblasts	0.2930	0.0560	9.6e-12	0.122	NA	0.153	NA	0.175	2.0e-09	NA	1.4e-11	NA	4.0e-13
4	GTEx	Esophagus Mucosa	0.1320	0.0430	3.6e-05	0.151	NA	0.147	NA	0.143	2.6e-10	NA	5.1e-10	NA	8.5e-10
5	GTEx	Heart Atrial Appendage	0.1220	0.0620	9.4e-03	-0.003	NA	0.004	NA	-0.001	4.8e-01	NA	2.1e-01	NA	3.7e-01
6	GTEx	Nerve Tibial	0.0768	0.0353	5.8e-03	0.043	NA	0.016	NA	0.039	5.0e-04	NA	2.5e-02	NA	9.1e-04
7	METSIM	Adipose	0.0523	0.0215	2.7e-03	-0.001	0.015	0.000	0.014	-0.001	4.3e-01	1.9e-03	3.6e-01	3.1e-03	5.8e-01
8	YFS	Blood	0.0692	0.0186	5.7e-11	0.021	0.034	0.033	0.034	0.031	1.2e-07	2.5e-11	5.3e-11	2.2e-11	1.8e-10
9	TCGA	Bladder Urothelial Carcinoma	0.0730	0.0390	2.2e-06	0.054	0.043	0.072	NA	0.065	2.2e-05	1.5e-04	1.1e-06	NA	3.6e-06
10	TCGA	Breast Invasive Carcinoma	0.0210	0.0149	3.6e-04	0.013	0.017	0.017	NA	0.017	9.4e-04	1.8e-04	1.8e-04	NA	1.5e-04
11	TCGA	Colon Adenocarcinoma	0.0640	0.0430	7.5e-03	0.059	0.038	0.042	NA	0.043	2.6e-04	2.9e-03	1.7e-03	NA	1.7e-03
12	TCGA	Glioblastoma Multiforme	0.0980	0.0670	7.2e-03	0.023	0.045	0.012	NA	0.027	6.7e-02	1.6e-02	1.3e-01	NA	5.0e-02
13	TCGA	Brain Lower Grade Glioma	0.0686	0.0427	2.9e-05	0.021	0.036	0.040	NA	0.035	1.8e-03	5.0e-05	2.2e-05	NA	7.2e-05
14	TCGA	Pancreatic Adenocarcinoma	0.2620	0.1010	4.7e-04	0.083	0.056	0.048	NA	0.073	2.3e-04	2.3e-03	4.4e-03	NA	5.6e-04
15	TCGA	Stomach Adenocarcinoma	0.0320	0.0230	5.0e-03	0.019	0.016	0.000	NA	0.012	1.5e-02	2.2e-02	3.1e-01	NA	4.1e-02
16	TCGA	Thyroid Carcinoma	0.3140	0.0930	9.8e-09	0.100	0.110	0.084	NA	0.089	6.1e-10	7.5e-11	1.4e-08	NA	5.3e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Smoking status: Previous	5.3	7.9	18.3	-3.2	-2.3	-1.4	-2.9	-2.4	2.6	-1.8	-1.4	-2.4	-3.6	-2.7	-4.3	-3.4	1.7	-4.0	-2.8
Medication: Blood pressure	5.1	9.8	16.2	4.0	3.5	2.4	3.4	3.3	-2.6	1.5	2.0	3.6	4.0	3.3	3.9	4.0	-1.0	3.7	0.6
Myopia	4.9	7.1	16.9	3.7	3.3	2.6	2.9	2.2	-1.5	1.1	0.8	2.7	3.1	3.0	3.4	4.1	-0.4	3.1	-0.0
Hypertension (Self-reported)	4.5	12.4	24.4	3.4	3.9	1.9	3.8	4.7	-3.9	1.3	1.2	4.1	4.9	3.6	4.5	4.2	-1.8	4.2	1.1
High blood pressure	4.1	11.3	22.2	3.3	3.8	2.0	3.7	4.4	-3.6	1.0	1.4	3.9	4.7	3.4	4.2	4.1	-1.6	3.9	0.8
Diabetes (father)	4.0	4.9	10.6	2.1	1.6	1.2	1.6	1.7	-3.2	2.0	1.6	1.2	2.4	0.5	3.3	2.4	-2.7	2.9	2.9
Vascular/heart problems diagnosed by doctor	4.0	10.9	21.4	-3.3	-3.7	-1.7	-3.5	-4.3	3.9	-1.2	-1.2	-3.9	-4.6	-3.1	-4.1	-3.9	1.8	-3.9	-0.9
Medication: Amlodipine	3.9	5.5	10.6	2.8	3.3	1.7	2.3	2.7	-2.0	0.9	2.0	2.5	2.8	2.1	2.9	2.8	-0.8	2.8	0.8
Cardiovascular Disease	3.8	12.6	27.3	3.3	3.8	0.7	3.9	5.2	-4.3	1.6	0.2	4.1	4.9	3.0	4.7	3.7	-2.3	4.4	1.7
Handedness (chirality/laterality): Left-handed	3.6	4.3	8.9	2.7	2.1	2.4	2.5	1.0	0.0	3.0	2.7	1.8	2.0	2.2	2.3	2.0	0.8	2.3	0.8
Systolic Blood Pressure	3.5	17.7	36.6	3.7	5.2	4.0	5.7	3.8	-2.6	3.9	1.3	6.1	5.7	5.3	4.7	3.5	0.5	4.9	0.7
Illnesses of father: High blood pressure	3.5	4.3	7.6	1.8	2.2	1.3	2.5	2.1	-1.6	2.6	0.3	2.4	2.8	2.3	2.7	1.9	-0.2	2.7	1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.3	3.9	7.2	-2.1	-2.7	-2.2	-2.4	-0.7	0.6	-1.6	-1.6	-2.1	-2.4	-2.5	-2.2	-2.6	-0.6	-2.2	-0.7
Ever depressed for a whole week	3.1	3.8	9.3	1.9	2.2	1.8	3.1	1.7	0.7	2.8	0.8	2.0	2.0	2.4	1.9	1.1	1.3	2.2	1.5
Mean Putamen Volume	3.0	3.4	7.7	2.1	2.2	1.2	2.3	1.7	-1.4	1.6	-0.4	2.8	2.4	2.2	2.2	1.5	-0.5	2.3	0.2
Chronic bronchitis/emphysema (father)	3.0	3.5	6.3	-2.3	-1.8	-0.9	-1.8	-2.2	1.6	-2.5	-0.5	-1.9	-1.9	-0.9	-2.5	-1.8	0.5	-2.5	-2.4
Hearing difficulty/problems with background noise	3.0	4.8	23.0	-0.1	0.5	2.1	0.5	1.0	4.8	2.5	2.2	-0.0	-1.8	0.8	-1.8	-1.1	4.5	-1.3	-2.2
Ever had stillbirth, spontaneous miscarriage or termination	3.0	3.2	10.0	2.4	2.3	0.8	1.5	1.5	-2.1	1.8	1.0	1.7	1.8	0.7	2.0	3.2	-1.6	1.8	-0.4
Blood Platelet Count	2.8	32.2	71.2	6.1	5.4	2.4	5.2	5.9	-8.4	2.9	0.2	5.5	7.7	3.2	8.1	6.8	-5.4	7.4	2.8
Schizophrenia (2014)	2.6	5.8	12.4	2.9	3.3	3.4	3.2	0.9	0.0	2.8	0.9	3.5	2.7	3.0	1.7	1.7	1.7	2.0	-1.3
Alcohol intake versus 10 years previously	2.6	3.9	9.4	-1.9	-2.6	-2.4	-2.1	-1.9	0.2	-3.1	-2.1	-2.0	-1.6	-2.0	-1.8	-2.3	-0.7	-2.0	-1.2
Ever highly irritable/argumentative for 2 days	2.6	3.2	7.1	2.5	1.9	-0.1	1.7	1.4	-1.3	2.0	1.0	1.4	2.1	1.8	2.3	2.7	-1.2	2.1	1.5
Illnesses of father: None of the above (group 1)	2.6	3.2	6.2	-1.8	-1.7	-1.4	-2.4	-2.1	0.5	-1.9	-0.8	-1.5	-2.1	-2.2	-2.0	-1.2	-0.4	-2.2	-2.5
Mouth/teeth dental problems: Loose teeth	2.5	2.9	8.8	3.0	1.9	2.1	1.9	0.4	-0.6	1.9	1.3	2.0	1.7	1.5	1.5	2.4	0.1	1.7	-0.5
Systolic blood pressure, automated reading	2.3	6.6	15.8	1.6	3.0	2.5	3.8	2.0	-1.6	2.0	0.9	3.8	4.0	3.6	2.6	2.1	0.7	2.7	-0.3
Supplements: Zinc	2.3	2.6	4.9	-1.7	-1.2	-1.2	-1.7	-0.5	1.6	-1.4	-1.7	-1.7	-2.2	-1.8	-2.2	-1.5	1.0	-2.1	-1.0
Alzheimer’s Disease (in father)	2.2	2.4	5.5	2.1	2.3	1.4	2.1	1.2	0.7	0.9	0.4	1.6	1.4	1.9	1.0	2.2	1.6	1.1	-1.3
Sitting height	2.2	15.8	45.0	-5.4	-5.7	-1.8	-4.2	-3.2	2.4	-3.2	-3.2	-4.4	-4.3	-3.5	-4.5	-6.7	0.5	-4.3	0.3
Medication: Atorvastatin	2.2	2.7	5.2	1.8	2.1	1.4	2.3	1.5	-1.1	0.8	-1.0	2.3	2.0	1.3	2.0	2.1	-0.0	1.9	0.2
Past tobacco smoking	2.1	3.9	10.0	2.1	1.4	0.6	2.1	1.4	-1.6	0.9	1.2	1.2	2.4	1.9	3.2	2.0	-1.2	3.0	3.0
Mother’s age at death	2.0	2.5	4.7	-2.0	-1.4	-2.1	-2.2	-1.6	0.3	-1.5	-0.3	-1.9	-1.9	-2.2	-1.7	-0.8	0.1	-1.9	-0.5
Schizophrenia (2018)	1.9	3.9	8.0	2.5	2.8	2.2	2.4	0.5	0.1	2.8	0.8	2.8	2.0	2.2	1.1	1.7	1.5	1.4	-1.8
Medication for hormone replacement therapy	1.9	2.1	5.1	-1.5	-1.5	-1.0	-1.5	-2.3	-0.7	-1.8	-2.1	-1.7	-1.1	-1.6	-0.9	-1.2	-1.5	-1.1	-0.1
Medication: Co-codamol	1.9	2.2	4.5	-1.9	-1.8	-1.9	-1.7	-1.0	0.0	-0.9	-0.6	-2.1	-1.6	-2.1	-1.6	-0.9	-0.8	-1.8	-0.3
Ever unenthusiastic/disinterested for a whole week	1.9	2.3	5.6	1.6	1.7	0.6	2.4	0.7	0.1	2.1	1.1	1.3	1.8	1.8	1.8	0.8	0.6	1.9	1.7
Mood swings	1.9	3.4	11.7	0.6	1.0	2.0	1.6	-0.9	3.2	2.5	2.7	0.7	0.0	1.9	-0.6	0.2	3.4	-0.3	-2.3
Hearing aid user	1.9	2.1	4.4	-2.0	-1.5	-0.7	-2.1	-1.5	0.9	-0.9	-0.4	-1.7	-1.8	-1.3	-1.8	-1.5	0.2	-1.9	-1.3
High cholesterol (Self-reported)	1.9	3.4	8.5	1.5	1.7	0.1	1.4	2.9	-2.4	1.1	-0.0	1.4	2.3	1.2	2.6	2.1	-1.8	2.4	1.8
Diabetes (mother)	1.8	2.3	6.6	-1.9	-1.5	-2.2	-1.5	-0.7	-2.0	-2.0	-0.6	-0.9	-0.6	-2.3	-0.6	-0.8	-2.6	-0.8	0.4
Relative age voice broke	1.8	2.8	8.8	-1.1	-0.2	-0.6	-0.8	-2.0	3.0	1.3	-0.5	-0.9	-2.0	-0.8	-2.2	-1.8	2.6	-1.8	-2.1
Stomach or abdominal pain in last month	1.8	2.2	4.2	1.9	1.9	1.1	2.1	0.8	-1.3	1.1	-0.3	1.6	2.0	1.4	1.8	1.4	-0.7	1.7	1.0
Gout (self-reported)	1.7	2.3	6.0	1.6	1.9	1.7	2.0	0.2	0.3	0.8	1.1	2.5	1.6	2.1	1.1	1.4	1.3	1.4	-1.0
Arm fat-free mass (right)	1.7	8.6	17.9	-4.1	-3.6	-2.2	-3.0	-2.6	0.3	-2.7	-4.0	-2.7	-2.6	-2.9	-3.4	-4.2	-1.2	-3.2	-1.0
Age at last live birth	1.7	2.4	8.9	-0.5	-0.8	0.9	-0.4	-1.6	2.8	0.5	1.1	-1.0	-1.4	0.0	-1.9	-0.9	2.5	-1.7	-3.0
Medication: Bendroflumethiazide	1.7	2.5	6.8	1.9	2.3	0.2	1.7	1.6	-1.6	0.3	-0.9	2.6	1.8	1.3	1.6	2.2	-0.7	1.6	-0.8
Mouth/teeth dental problems	1.6	2.5	5.5	-2.3	-2.2	-1.2	-1.6	-0.6	0.6	-1.1	-2.0	-1.8	-1.5	-1.8	-1.5	-2.3	0.2	-1.4	1.0
Worrier / anxious feelings	1.6	3.1	6.0	-1.4	-1.7	-0.3	-1.3	-1.9	2.3	0.7	2.4	-1.7	-1.9	-0.9	-2.3	-1.2	1.7	-2.3	-2.2
Mouth/teeth dental problems: Dentures	1.6	2.6	7.8	1.8	2.3	-0.3	0.8	1.5	-2.4	0.0	0.7	1.3	1.9	1.4	1.8	2.8	-2.0	1.4	-0.6
Hair/balding pattern: Pattern 4	1.6	3.8	11.0	-3.3	-3.3	-0.5	-1.6	-1.1	-0.6	-2.0	-2.5	-1.8	-1.0	-1.9	-1.9	-2.6	-0.7	-2.0	-1.0
Number of full sisters	1.6	1.9	4.9	-1.5	-1.3	-1.4	-2.1	-1.8	-0.7	-1.4	-0.9	-1.4	-1.4	-2.2	-1.1	-0.9	-1.0	-1.3	-0.5
Commuting to job workplace: Walk	1.6	1.8	4.9	0.9	2.1	0.9	1.7	1.2	1.2	1.3	1.4	2.2	0.4	1.3	0.3	0.6	2.2	0.8	-0.1
Average weekly beer plus cider intake	1.6	2.3	6.0	-1.5	-1.6	-1.0	-1.9	-2.4	0.4	-0.3	-1.6	-1.4	-1.4	-1.2	-1.9	-1.8	-0.5	-1.9	-1.4
LDL Cholesterol	1.5	2.4	4.6	1.6	1.9	1.7	1.6	1.0	-1.0	2.1	-0.1	1.2	2.0	1.7	2.0	2.1	-0.5	1.9	0.4
Ever used hormone-replacement therapy (HRT)	1.5	1.9	6.9	-1.8	-1.1	-1.4	-1.1	-2.6	0.8	-1.4	-1.7	-0.9	-1.0	-0.7	-1.6	-1.7	0.8	-1.4	-0.4
Medication: Atenolol	1.5	1.9	5.4	2.3	1.3	0.3	1.3	2.0	-1.0	0.4	1.2	1.9	1.1	0.8	1.8	1.0	-0.8	1.9	1.0
Trunk fat-free mass	1.5	8.5	17.6	-4.1	-3.9	-2.0	-3.3	-2.0	0.7	-2.9	-3.4	-3.0	-2.9	-2.9	-3.3	-4.2	-0.9	-3.1	-0.3
Trunk predicted mass	1.5	8.4	17.6	-4.0	-3.9	-2.0	-3.2	-2.0	0.7	-2.8	-3.5	-2.9	-2.9	-2.9	-3.3	-4.2	-0.9	-3.1	-0.3
Age at first live birth	1.5	2.6	9.2	-0.0	-0.6	0.1	-0.9	0.4	3.0	1.9	1.2	-1.0	-2.1	-0.8	-2.0	-0.8	2.7	-1.9	-2.1
Arm fat-free mass (left)	1.5	7.6	14.8	-3.8	-3.4	-2.3	-2.9	-2.0	0.0	-2.6	-3.7	-2.7	-2.4	-2.9	-3.0	-3.6	-1.6	-3.0	-1.1
Arm predicted mass (left)	1.5	7.8	15.2	-3.9	-3.5	-2.3	-3.0	-2.0	0.1	-2.7	-3.7	-2.6	-2.5	-2.9	-3.1	-3.8	-1.5	-3.0	-1.0
Bipolar Disorder or Schizophrenia	1.4	3.4	7.1	2.2	2.7	1.8	2.4	-0.2	0.3	2.4	0.2	2.6	1.8	2.1	0.6	1.8	1.3	0.9	-2.5
Schizophrenia vs Biploar Disorder	1.4	1.8	4.5	1.3	1.0	2.1	1.7	1.6	-0.3	1.7	-0.7	1.7	1.7	1.8	1.2	0.6	0.1	1.3	0.3
Peak expiratory flow (PEF)	1.4	3.2	6.0	1.4	2.3	1.3	1.2	1.7	-2.2	1.6	0.8	2.0	2.1	1.4	2.4	2.0	-1.5	2.4	1.0
Medication: Ventolin 100micrograms inhaler	1.4	1.8	5.0	-1.1	-1.3	-0.7	-1.3	-0.0	1.6	0.0	-0.1	-1.6	-1.6	-0.9	-2.2	-1.7	1.1	-2.1	-1.1
Qualifications: College or University degree	1.4	4.5	13.6	-1.5	-2.3	-0.5	-1.8	-1.0	3.7	1.4	-1.1	-2.5	-2.9	-1.4	-2.5	-2.9	2.4	-2.3	-0.6
Mean time to correctly identify matches	1.4	2.6	5.7	2.2	2.4	0.2	1.8	1.1	-1.2	0.3	1.2	2.4	1.8	1.2	1.9	2.3	-0.0	2.0	0.7
Arm predicted mass (right)	1.4	7.3	15.8	-3.9	-3.4	-2.1	-2.6	-2.2	0.0	-2.6	-3.9	-2.4	-2.2	-2.6	-3.0	-4.0	-1.4	-2.9	-0.7
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.7	5.1	-1.2	-1.2	-0.7	-1.3	0.9	-2.0	-1.7	-1.9	-1.0	-0.3	-1.7	0.0	-0.9	-2.3	-0.2	1.0
Alcohol drinker status: Never	1.4	1.7	3.5	1.5	1.9	1.5	1.6	1.8	0.4	1.1	0.5	0.4	1.1	1.7	1.6	1.5	0.5	1.5	0.1
Medication: Lansoprazole	1.3	1.5	4.8	0.0	-0.9	-1.6	-1.6	-0.1	0.1	0.7	-2.2	-1.6	-1.7	-2.0	-1.0	-1.2	-0.5	-1.1	-0.4
Medication for cholesterol	1.3	1.9	5.8	-1.2	-1.2	0.0	-0.6	-1.9	2.4	0.2	-0.1	-1.0	-1.6	-0.5	-1.9	-2.0	1.9	-1.6	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.8	6.2	2.4	2.1	1.6	1.9	0.2	-0.1	2.5	0.7	2.1	1.6	1.7	1.9	1.7	0.8	2.1	0.6
Ever taken oral contraceptive pill	1.3	1.4	5.1	1.6	1.2	1.6	1.5	-0.6	0.8	0.3	2.3	1.2	0.8	1.3	1.1	1.0	0.7	1.2	0.5
Fractured/broken bones in last 5 years	1.3	1.7	5.1	1.0	1.1	1.1	1.5	2.3	-1.4	1.6	0.4	1.0	1.7	0.9	1.4	1.8	-0.9	1.2	0.2
Lung FEV1/FVC ratio	1.2	6.3	23.9	2.5	2.0	1.1	1.9	0.2	-4.9	-0.1	0.2	2.8	3.6	1.4	3.4	2.4	-3.5	3.0	0.4
Standing height	1.2	11.9	21.1	-4.0	-4.6	-3.3	-4.4	-2.7	1.7	-2.2	-3.1	-4.1	-4.2	-3.5	-4.1	-4.3	-0.2	-4.0	-0.2
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	7.5	-0.4	-2.0	0.2	-1.6	-2.7	1.4	-0.4	0.3	-2.1	-1.6	-1.0	-1.8	-1.0	0.5	-1.8	-1.0
Medication: Blood pressure	1.2	2.0	7.8	0.5	1.9	-0.1	1.5	2.8	-1.8	0.8	-0.6	1.8	1.6	0.7	1.7	1.2	-1.0	1.6	0.4
Supplements: Fish oil (including cod liver oil)	1.2	1.6	5.9	-1.9	-0.9	-0.8	-0.9	-0.5	0.9	-2.4	-0.6	-0.6	-1.4	-0.9	-1.6	-1.8	1.1	-1.4	-0.3
Medication: Lisinopril	1.2	1.5	3.5	1.4	0.9	0.2	1.6	1.9	-1.1	0.2	0.4	1.5	1.7	1.3	1.6	1.3	-0.5	1.5	0.7
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.4	8.1	-2.6	-1.7	-0.3	-0.8	-1.8	1.6	-1.4	-0.2	-0.8	-1.8	-1.5	-1.7	-2.8	1.0	-1.3	0.6
High blood pressure (mother)	1.1	1.5	4.2	1.0	1.3	0.8	1.6	-0.3	-0.5	1.0	0.8	1.1	1.8	1.7	1.4	2.0	0.3	1.4	0.7
Alcohol usually taken with meals	1.1	1.8	5.0	0.8	1.0	1.0	2.1	1.1	1.3	0.7	2.2	0.9	1.0	1.7	0.9	1.3	1.8	1.1	1.1
Time employed in main current job	1.1	1.3	3.7	0.1	1.2	-0.3	0.2	-0.7	-1.9	-0.4	0.4	0.9	1.6	1.0	1.5	1.1	-1.6	1.3	1.5
Whole body fat-free mass	1.1	6.2	10.9	-3.3	-3.2	-1.9	-2.9	-1.6	0.3	-2.6	-3.3	-2.6	-2.4	-2.6	-2.7	-3.3	-1.2	-2.6	-0.3
Whole body water mass	1.1	6.1	11.4	-3.3	-3.2	-1.9	-2.8	-1.5	0.4	-2.6	-3.2	-2.5	-2.5	-2.6	-2.7	-3.4	-1.1	-2.6	-0.3
Neuroticism (Nagel 2018)	1.0	2.4	7.4	-0.4	-0.6	0.2	0.0	-2.0	2.7	2.0	2.2	-0.5	-1.2	0.1	-1.7	-0.6	2.2	-1.5	-2.5
Ulcerative Colitis (UC)	1.0	1.9	9.5	0.6	1.6	1.2	1.3	-0.4	2.5	1.5	1.1	1.1	0.2	1.7	-0.1	0.3	3.1	0.2	-0.8
Reaction Time	1.0	1.9	5.4	2.3	1.8	0.2	1.6	0.8	-0.5	0.6	1.3	1.8	1.5	1.2	1.6	1.9	0.5	1.7	0.7
Triglycerides	1.0	1.6	4.0	0.9	1.1	0.3	1.0	0.4	-2.0	0.8	-0.1	0.6	1.8	1.0	2.0	1.6	-1.1	1.8	1.5
Type 2 Diabetes (T2D) (2012)	1.0	1.2	4.1	-1.7	-1.2	-0.6	-0.8	-2.0	-0.6	-0.6	-0.6	-1.3	-0.6	-1.2	-0.8	-1.1	-1.0	-1.0	0.5
Height	1.0	20.1	36.1	-4.9	-6.0	-5.2	-5.5	-2.8	1.7	-3.9	-4.1	-5.9	-5.0	-4.8	-4.8	-5.7	-0.2	-4.7	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	3.4	1.8	1.0	1.8	1.2	0.3	0.4	1.8	0.2	0.8	1.0	1.6	0.9	1.3	0.7	0.8	-0.5
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	7.8	-0.7	-1.1	-1.0	-0.5	-1.0	-0.9	-0.6	-0.5	-1.1	-0.1	-0.9	0.1	-1.3	-1.2	0.1	2.8
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	6.7	-2.6	-1.2	-0.3	-0.9	-2.2	1.5	-1.2	0.1	-0.5	-1.8	-1.4	-1.9	-2.3	1.0	-1.6	-0.8
Neuroticism score	1.0	2.0	6.0	-0.2	-0.4	0.1	0.2	-2.3	2.4	1.4	2.0	-0.4	-1.1	0.3	-1.4	-0.1	2.0	-1.3	-2.3
Impedance of arm (right)	1.0	4.7	18.2	4.0	2.7	0.3	1.2	2.3	-0.2	2.3	2.1	1.1	1.0	1.5	2.5	4.3	0.5	2.2	0.9
Birth weight	1.0	2.3	7.7	-1.6	-1.4	-0.8	-1.5	-0.3	2.8	0.7	0.0	-1.3	-2.2	-1.0	-1.8	-2.2	1.7	-1.4	-0.3
Worry too long after embarrassment	1.0	1.7	9.8	0.2	0.3	0.8	1.4	-0.9	2.1	1.8	3.1	0.0	-0.1	0.8	-0.5	0.4	2.1	-0.3	-0.6
Neck or shoulder pain in last month	1.0	1.4	3.0	1.4	1.4	0.6	1.0	1.0	-1.5	0.3	-1.2	1.7	1.2	0.9	1.2	1.7	-0.9	1.2	0.3
Supplements: Vitamin C	1.0	1.1	3.4	-0.6	-1.2	-1.9	-1.2	1.1	0.5	0.2	-1.0	-1.1	-1.3	-1.2	-1.3	-1.2	-0.1	-1.3	-0.1
Arm fat percentage (left)	1.0	3.9	11.5	2.0	2.2	-0.3	0.8	2.3	-3.0	-0.5	-2.5	1.3	1.6	0.1	1.8	3.4	-2.9	1.3	-1.6
Medication: Aspirin	1.0	1.4	9.6	1.0	1.4	-0.0	1.1	3.1	-0.5	0.2	-1.7	1.3	0.8	0.4	1.0	0.1	-0.1	1.1	0.2
Cholesterol lowering medication	1.0	1.5	7.3	0.9	1.1	-0.3	0.4	2.7	-1.5	1.0	-0.2	0.4	1.3	0.5	1.4	1.8	-1.3	1.1	0.7
Intelligence (Savage-Jansen 2018)	0.9	2.8	5.5	-1.7	-2.2	-1.8	-2.0	-0.8	1.5	-0.7	0.3	-2.2	-2.3	-1.9	-2.0	-1.9	1.0	-1.9	0.2
Fasting Glucose	0.9	1.1	4.2	-0.2	-0.8	-0.3	0.2	0.3	-1.7	-1.5	-0.6	-0.6	1.5	-0.1	1.0	0.5	-2.1	0.7	1.8
Heel T-Score	0.9	7.3	26.7	-3.1	-1.9	-0.0	-0.2	-1.9	4.5	-0.3	-2.3	-0.2	-1.9	0.1	-3.6	-5.2	4.2	-2.6	-2.6
Angina	0.9	1.2	4.1	1.3	0.7	-0.2	0.5	2.0	-1.7	-0.2	0.1	1.0	1.2	0.3	1.5	1.1	-0.8	1.5	1.2
Current tobacco smoking	0.9	1.5	3.3	1.4	1.3	-0.7	0.6	-0.5	-1.8	-0.5	0.9	1.3	1.2	0.6	1.7	1.1	-1.3	1.7	1.7
Maternal smoking around birth	0.9	1.4	7.3	-0.6	-1.3	-0.5	-1.3	-1.1	-1.2	-2.7	-1.2	-1.2	-0.4	-1.1	0.1	-0.4	-1.6	-0.1	1.1
Medication: Levothyroxine sodium	0.9	1.6	3.5	1.4	1.0	0.5	1.4	1.6	-1.1	0.5	-0.3	1.3	1.5	0.9	1.6	1.3	-0.6	1.7	1.9
Financial difficulties in last 2 years	0.9	1.3	5.3	1.4	0.7	-0.0	1.1	0.7	-1.2	1.4	0.8	0.5	1.1	0.3	1.4	2.3	-1.4	1.0	-0.1
Arm fat percentage (right)	0.9	3.7	11.9	1.9	2.1	-0.4	0.6	2.1	-3.0	-0.6	-2.3	1.1	1.5	-0.1	1.7	3.5	-3.0	1.2	-1.7
Depression (self-reported)	0.9	1.1	4.7	0.6	0.7	2.2	1.3	-0.6	0.2	0.9	0.2	1.2	1.0	1.5	0.4	1.3	0.2	0.5	-1.6
Lung cancer (father)	0.9	1.0	4.6	-0.1	-0.6	-0.9	-0.9	-2.2	0.4	-1.1	1.0	-0.5	-1.1	-1.0	-1.1	-0.6	-0.4	-1.1	-1.5
Impedance of arm (left)	0.9	4.4	15.0	3.9	2.8	0.4	1.4	2.3	-0.1	2.0	1.9	1.3	1.1	1.7	2.4	3.9	0.6	2.1	0.9
Birth weight of first child	0.9	1.6	5.7	1.3	1.3	0.9	0.9	0.1	1.2	2.4	1.3	1.3	0.5	1.5	0.7	-0.8	1.8	1.1	1.7
Blood clot in the leg (DVT)	0.9	1.2	3.0	-1.4	-1.3	-1.6	-1.2	-0.9	-0.3	-1.1	-1.6	-1.7	-0.6	-0.8	-0.7	-0.8	-1.0	-0.9	0.4
Body fat percentage	0.9	3.5	10.5	1.2	1.7	-0.9	0.4	1.4	-3.1	-0.7	-3.2	1.0	1.2	-0.4	1.1	2.8	-3.2	0.5	-2.3
Medication: Aspirin	0.9	1.2	8.1	0.7	1.5	0.4	1.0	2.8	-0.3	0.6	-1.7	1.4	0.7	0.5	0.8	-0.0	0.3	0.9	0.2
Illnesses of father: Heart disease	0.9	1.3	4.9	1.0	0.2	0.3	1.7	1.1	0.4	0.5	-0.8	0.7	1.2	1.7	1.3	-0.3	0.6	1.5	2.2
Smoking status: Current	0.9	1.4	3.8	1.3	1.1	-0.6	0.6	-0.4	-2.0	-0.6	0.4	1.3	1.3	0.5	1.6	1.2	-1.3	1.5	1.5
Basal metabolic rate	0.9	5.1	12.3	-2.9	-2.8	-1.8	-2.6	-1.3	-0.1	-2.5	-3.5	-2.2	-2.0	-2.4	-2.3	-2.7	-1.6	-2.3	-0.7
Diastolic blood pressure, automated reading	0.9	2.8	6.7	0.8	1.9	1.8	2.5	1.6	-0.8	1.8	-0.2	2.6	2.5	2.5	1.1	1.0	0.5	1.2	-1.3
Prostate Cancer	0.8	1.1	2.9	0.4	0.6	-0.9	0.5	0.5	-1.5	-0.5	1.1	0.4	0.9	0.2	1.5	1.6	-1.7	1.2	1.7
Lupus	0.8	1.2	2.5	-0.2	-0.9	-1.3	-1.5	-0.9	0.5	-0.1	-1.6	-1.0	-1.5	-1.6	-1.3	-0.5	-0.2	-1.3	-0.9
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	4.4	0.9	0.1	-0.6	-0.9	2.1	-1.1	-1.5	-0.8	-0.2	-0.5	-1.1	0.6	0.2	-1.3	0.4	1.4
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	3.4	0.5	-0.1	-0.7	0.3	0.6	-1.7	-1.0	1.3	0.4	1.0	0.1	1.1	0.8	-1.8	0.9	0.9
Trunk fat percentage	0.8	3.1	10.6	0.9	1.3	-1.8	-0.3	1.3	-2.6	-1.2	-3.2	0.3	0.5	-1.0	0.6	2.6	-3.1	0.0	-2.2
Supplements: Glucosamine	0.8	1.0	3.3	-0.9	-0.6	-1.4	-1.0	-0.5	-0.6	-1.8	-1.3	-1.2	-0.7	-1.2	-0.9	-0.3	-1.1	-1.0	0.1
Loud music exposure frequency	0.8	0.9	4.9	-0.3	0.6	0.5	-0.1	0.2	2.1	0.7	1.0	0.0	-1.0	-0.0	-0.9	-0.4	2.2	-0.7	-0.8
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	2.7	1.2	0.9	1.6	1.6	-0.2	0.5	0.7	1.3	1.5	0.8	1.2	1.0	0.7	0.9	1.1	0.1
High blood pressure (siblings)	0.8	1.1	3.0	0.3	0.8	1.7	1.7	0.2	0.2	0.9	1.4	1.6	1.2	1.3	0.7	0.1	1.0	1.0	-0.3
Leg fat percentage (right)	0.8	2.8	10.4	0.3	1.2	-0.6	0.5	0.6	-3.2	-1.0	-3.0	1.1	1.6	-0.3	0.7	1.6	-3.1	0.4	-2.2
Wheeze or whistling in the chest in last year	0.8	1.4	4.4	-0.1	1.0	1.4	1.6	0.7	1.5	-0.1	1.3	1.2	0.7	1.6	-0.5	0.4	1.8	-0.2	-2.1
Angina (self-reported)	0.8	1.1	3.6	1.2	0.6	-0.3	0.3	1.9	-1.7	-0.3	-0.2	0.8	1.0	0.1	1.4	1.0	-0.9	1.3	1.3
Medication: Allopurinol	0.8	1.1	4.0	0.4	0.9	1.1	1.1	-1.0	1.4	0.9	1.6	1.1	0.3	1.1	0.1	0.1	2.0	0.3	-1.2
Had major operations	0.8	0.9	2.7	-0.8	-0.7	-0.1	-1.6	0.0	0.2	-1.0	0.5	-1.3	-1.5	-1.5	-0.8	-0.4	-0.1	-1.1	-0.9
Long-standing illness, disability or infirmity	0.8	1.2	3.5	1.6	1.9	0.7	1.0	1.5	0.5	1.7	0.7	1.2	0.4	0.7	0.5	0.7	1.2	0.6	-1.1
Leg fat percentage (left)	0.8	3.0	13.5	0.0	0.9	-0.7	0.1	0.7	-3.1	-1.4	-3.7	0.8	1.1	-0.8	0.4	1.4	-3.2	-0.0	-2.7
Ever had prostate specific antigen (PSA) test	0.8	0.9	6.1	0.5	1.1	0.8	0.8	0.9	0.2	0.5	2.5	1.2	0.6	1.2	0.4	1.0	0.5	0.6	0.0
Unable to work because of sickness or disability	0.8	1.0	3.5	-1.0	-1.2	-1.7	-1.4	-1.9	-0.3	-0.9	-0.4	-0.9	-0.6	-0.8	-0.6	-0.8	-0.4	-0.8	0.5
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.9	-1.3	-1.3	-1.5	-1.0	-0.6	-0.3	-0.8	-1.7	-1.7	-0.5	-0.7	-0.7	-0.7	-0.9	-0.8	0.2
Worry (Nagel 2018)	0.7	1.4	4.2	-0.5	-1.0	-1.1	-0.4	-2.0	1.5	1.0	0.9	-0.5	-1.0	-0.2	-1.4	-0.8	1.1	-1.4	-2.1
Hand grip strength (left)	0.7	1.9	6.3	-2.5	-1.3	0.1	-0.5	-1.6	1.7	0.3	-1.1	-0.5	-0.8	-0.1	-1.8	-2.3	1.4	-1.5	-1.4
Relative age of first facial hair	0.7	1.5	3.7	-0.6	-0.3	-1.5	-1.7	-1.7	1.2	1.1	-0.3	-1.4	-1.9	-1.6	-1.1	-0.7	0.9	-1.0	1.0
Medication: Metformin	0.7	1.0	4.0	0.1	-0.2	0.5	0.7	1.1	-2.0	0.2	-0.7	0.6	1.4	0.2	1.3	0.6	-1.8	1.1	0.8
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	2.4	-1.1	-1.0	-0.5	-0.7	0.1	0.4	-1.6	1.0	-1.4	-0.8	-0.7	-0.9	-0.7	-0.4	-1.0	0.3
Qualifications: CSEs or equivalent	0.7	0.9	3.5	-0.5	-0.9	-0.5	-0.1	-1.9	-1.3	-0.4	1.6	-0.1	0.3	-0.2	0.7	-0.5	-1.3	0.6	1.5
Serious illness, injury or assault to yourself	0.7	0.9	2.1	-1.3	-1.1	-1.1	-1.2	0.0	-0.9	-1.2	0.1	-0.8	-0.6	-1.0	-0.2	-0.9	-1.4	-0.4	0.8
Trunk fat mass	0.7	2.9	14.2	-0.1	0.3	-1.9	-0.9	0.7	-2.4	-1.8	-3.8	-0.3	-0.1	-1.5	-0.1	1.4	-3.2	-0.6	-2.0
Waist circumference	0.7	2.5	10.6	0.4	0.6	-1.3	-0.2	1.0	-2.8	-0.6	-3.3	0.4	0.9	-0.7	0.5	1.8	-3.1	0.0	-1.9
Hair/balding pattern: Pattern 2	0.7	0.9	2.3	0.6	1.4	0.9	1.0	-0.7	0.7	1.5	1.4	1.0	0.4	1.1	0.3	0.2	0.7	0.4	-1.1
Medication: Ramipril	0.7	0.8	3.6	0.1	1.9	1.2	0.9	0.9	0.6	0.9	0.2	1.1	0.3	0.8	0.4	0.9	0.9	0.4	-1.2
Chest pain or discomfort	0.7	1.1	3.0	1.1	0.7	-0.2	0.6	1.1	-1.7	1.3	0.0	1.0	1.2	0.3	1.3	1.5	-1.1	1.1	0.6
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.3	-0.6	-0.2	1.0	1.1	-1.1	-1.1	0.1	-0.9	0.3	1.5	1.1	1.0	0.8	-1.0	0.8	-0.0
Loneliness, isolation	0.7	1.0	3.6	1.6	1.2	0.8	1.1	-0.5	-0.6	0.9	-0.0	1.0	0.9	0.7	0.6	1.9	-0.1	0.5	-1.4
Mouth/teeth dental problems: Mouth ulcers	0.7	1.0	2.7	-0.6	-1.1	-0.3	-1.1	0.8	0.9	0.2	-1.2	-1.1	-1.1	-0.5	-1.4	-0.8	0.4	-1.5	-1.7
Mineral and other dietary supplements	0.7	0.9	3.7	1.2	0.6	0.5	0.5	0.6	-1.1	1.9	0.6	0.7	1.0	0.4	1.3	0.9	-1.1	1.2	0.5
Number of self-reported non-cancer illnesses	0.7	1.1	4.8	1.0	1.4	0.2	0.9	2.2	-1.0	-0.0	0.6	1.0	1.3	0.9	1.2	1.4	-0.4	1.1	0.0
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.1	1.1	1.0	0.4	0.9	-0.0	0.5	1.1	1.5	0.5	0.7	1.2	0.0	1.4	1.0	0.1	-1.2
Eye problems/disorders: Glaucoma	0.7	0.9	3.1	-0.8	-1.7	-1.2	-0.8	0.2	-0.8	-0.7	1.7	-0.8	-0.4	-0.6	-0.5	-1.0	-0.9	-0.5	0.9
Ever smoked	0.7	1.3	4.6	-0.9	-0.6	0.1	-1.4	-0.8	0.7	0.0	-0.7	-0.3	-1.5	-1.2	-1.8	-1.0	0.7	-1.6	-2.1
Leg fat mass (left)	0.7	2.5	14.5	-0.6	0.2	-1.0	-0.4	0.3	-2.5	-1.7	-3.8	0.2	0.5	-1.1	-0.1	0.6	-2.9	-0.4	-2.2
Irritable Bowel Disease (IBD)	0.6	1.4	8.2	0.1	1.1	1.4	0.7	-0.0	2.4	0.3	1.0	0.7	-0.5	0.7	-0.6	-0.1	2.9	-0.5	-1.3
Major Depression (MDD)	0.6	0.7	2.2	0.6	1.2	0.7	1.2	0.2	0.7	0.4	0.8	0.8	0.6	0.9	0.5	1.1	1.5	0.6	0.1
Smoking Status	0.6	1.3	5.2	-0.8	-0.7	-1.3	-0.9	-2.3	0.8	-1.7	-0.9	-0.7	-1.3	-1.0	-1.4	-1.3	0.5	-1.2	-0.2
Type 2 Diabetes (T2D) (2018)	0.6	1.1	4.6	-0.9	-1.1	-0.5	-0.2	0.2	-1.6	-1.3	0.7	-0.6	0.3	-1.2	0.7	-0.4	-1.7	0.5	2.1
Hearing difficulty/problems: Yes	0.6	0.9	4.5	-0.7	0.1	0.9	0.3	1.5	2.1	0.5	1.4	-0.2	-0.6	0.8	-0.6	-0.3	1.7	-0.5	-0.5
Weight	0.6	3.1	14.0	-1.6	-1.3	-1.7	-1.7	-0.3	-1.4	-2.1	-3.7	-1.2	-0.9	-1.9	-1.3	-0.6	-2.4	-1.5	-1.7
Falls in the last year	0.6	0.8	2.5	1.2	0.8	1.6	0.6	-0.7	0.2	-0.6	-0.6	1.1	0.6	1.0	0.3	1.2	0.6	0.4	-1.0
Noisy workplace	0.6	0.8	3.1	-1.1	-0.3	-0.7	-0.4	-0.1	1.1	0.9	0.4	-0.1	-0.7	-0.1	-1.4	-1.0	0.7	-1.2	-1.7
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	5.6	0.4	-0.4	-2.4	-0.3	1.1	-0.3	0.1	-0.1	-0.7	-0.3	-0.5	0.3	0.1	-0.9	0.3	1.7
Length of working week for main job	0.6	0.7	4.5	-0.0	0.5	0.6	0.4	-2.1	-0.2	-1.7	-0.0	-0.0	0.7	0.5	0.0	0.9	-0.2	-0.2	-1.1
Exposure to tobacco smoke at home	0.6	0.7	4.6	-0.8	-0.8	-0.4	-0.5	-0.9	-0.0	-2.1	0.5	-0.3	-0.5	-0.4	-0.8	-0.8	-0.7	-0.8	-0.8
Comparative body size at age 10	0.6	1.6	7.1	1.6	-0.1	-0.6	-0.8	1.9	-2.5	0.2	0.5	-0.5	0.5	-0.9	0.9	1.7	-2.7	0.4	0.1
Number of full brothers	0.6	0.8	2.7	-1.6	0.0	-1.3	-0.8	-1.6	0.4	-1.1	-0.2	-0.7	-0.6	-0.5	-0.8	-0.9	0.2	-0.8	0.1
Emphysema/chronic bronchitis	0.6	0.7	2.1	-0.7	-0.5	0.2	-1.0	-1.0	0.8	-0.1	0.8	-0.6	-0.9	-0.7	-1.1	-0.7	0.8	-1.0	-1.4
Migraine (self-reported)	0.6	0.7	1.9	-0.5	-0.1	-0.4	-1.1	-1.1	0.3	-1.4	0.0	-1.2	-1.0	-1.2	-0.8	0.3	0.3	-0.9	-0.6
Whole body fat mass	0.6	2.6	14.0	-0.0	0.5	-1.5	-0.5	0.7	-2.4	-1.5	-3.7	0.0	0.3	-1.1	0.0	1.3	-3.0	-0.4	-1.9
Leg fat mass (right)	0.6	2.2	11.8	-0.5	0.4	-0.9	-0.2	0.3	-2.5	-1.5	-3.4	0.4	0.7	-0.8	0.1	0.7	-2.9	-0.2	-1.9
Family relationship satisfaction	0.6	0.7	3.3	0.2	-0.1	0.1	0.4	0.3	1.5	-0.8	1.8	0.2	-0.4	0.6	-0.4	0.0	1.6	-0.3	-1.0
Leg pain on walking	0.6	0.8	4.0	-0.4	0.0	0.1	0.1	-0.4	1.9	-0.6	-0.0	0.2	-0.6	0.6	-1.2	-0.7	2.0	-0.8	-0.9
Ever had bowel cancer screening	0.6	0.7	2.2	0.4	0.8	1.3	1.3	-0.5	0.4	-0.2	0.7	1.5	0.7	1.0	0.2	0.8	0.9	0.4	-1.2
Average weekly champagne plus white wine intake	0.6	0.8	3.0	0.9	0.2	0.3	0.9	1.5	-0.1	1.7	1.1	-0.0	0.7	0.5	1.1	0.6	-0.2	1.1	1.0
Guilty feelings	0.6	0.8	2.7	0.9	0.5	0.3	0.6	-1.6	1.2	1.6	1.5	0.1	-0.1	0.4	-0.3	0.6	1.0	-0.2	-1.1
Number of operations (self-reported)	0.6	0.9	2.7	-1.1	-1.0	-0.8	-1.2	-0.0	-0.8	-1.7	0.4	-1.1	-0.8	-1.4	-0.3	0.0	-1.4	-0.5	0.3
Depression (Nagel 2018)	0.5	0.7	4.5	0.9	0.3	0.6	0.7	-0.8	0.6	2.1	0.9	0.0	0.7	1.2	0.5	0.7	0.7	0.4	0.1
Alzheimer’s Disease (including proxy)	0.5	0.7	3.4	0.5	1.0	0.8	0.7	1.0	0.7	-0.6	-0.4	0.7	0.6	1.0	-0.3	0.9	1.2	-0.2	-1.8
Ovarian Cancer	0.5	0.7	2.8	-0.1	0.3	-0.1	-0.5	-0.6	1.7	1.3	0.5	0.2	-1.4	-0.5	-0.6	-0.2	1.3	-0.4	-0.8
Age at First Birth	0.5	0.8	5.9	-0.5	-0.1	-0.1	-0.7	0.5	1.1	-0.1	-2.4	-0.5	-1.3	-0.8	-0.8	-0.2	0.5	-0.7	-0.6
Primary Biliary Cirrhosis	0.5	0.8	3.4	-0.6	0.4	-0.2	-0.3	-0.4	-1.7	0.3	-0.5	-0.0	0.5	-0.2	-0.1	1.2	-1.8	-0.5	-1.8
Blood Red Count	0.5	4.5	19.8	-1.1	0.5	1.8	1.6	-0.1	4.0	2.7	-1.4	1.6	-0.1	2.4	-1.6	-2.9	4.4	-0.4	-0.2
Respiratory disease	0.5	1.1	2.7	-0.9	-0.8	0.1	-1.0	0.2	1.3	-0.1	1.4	-1.0	-1.1	-0.3	-1.7	-1.0	0.7	-1.6	-1.4
Neuroticism	0.5	1.2	4.8	-0.3	-0.0	-0.5	0.3	-1.7	1.9	1.1	2.2	-0.4	-0.9	0.1	-0.9	-0.2	1.5	-0.8	-1.3
Sensitivity / hurt feelings	0.5	0.8	4.3	-0.5	0.1	0.7	0.3	-2.1	0.9	0.7	1.4	-0.1	-0.2	0.5	-0.6	0.6	0.9	-0.7	-1.3
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.8	-0.1	-1.0	0.4	-0.4	-0.4	0.9	1.7	-0.6	-1.0	-0.6	-0.1	-0.9	-0.7	0.4	-1.0	-1.3
Severe depression (siblings)	0.5	0.5	2.6	-0.1	-0.5	-0.7	-0.6	0.2	0.1	-1.5	-1.6	-0.7	-0.7	-0.8	-0.6	-0.5	0.1	-0.6	-0.1
Nervous feelings	0.5	0.9	6.7	-0.1	-1.2	-0.8	-0.6	-0.7	0.6	0.5	-0.4	-0.5	-0.7	-0.4	-1.1	-0.4	0.4	-1.1	-2.6
Had menopause	0.5	0.6	3.2	-1.1	-0.7	-1.1	-0.4	0.5	-0.2	-1.1	-1.8	-0.1	-0.1	-0.2	-0.6	-1.0	-0.2	-0.5	0.5
Had other major operations	0.5	0.7	3.7	0.5	0.7	-0.3	0.4	0.6	-1.2	0.4	0.3	1.0	0.5	0.2	0.5	1.9	-1.3	0.3	-0.8
Pain all over the body in last month	0.5	0.6	3.6	-0.3	-0.7	-1.9	-0.6	0.1	-0.4	0.0	-1.7	-0.7	-0.2	-0.6	-0.1	-0.8	-0.1	-0.2	0.1
Hair/balding pattern: Pattern 3	0.5	0.8	1.8	0.9	0.5	0.8	0.4	1.1	-1.4	-0.3	-0.1	0.1	1.3	0.6	1.1	1.1	-0.9	0.9	1.2
Forced expiratory volume in 1-second (FEV1)	0.5	1.7	3.9	1.2	1.4	0.8	0.9	-0.2	-1.3	1.7	0.9	1.1	1.5	1.2	2.0	1.4	-0.8	1.9	1.4
Pulse rate	0.5	0.8	2.0	0.2	1.2	1.1	1.4	0.2	0.0	1.1	0.7	1.1	1.2	1.4	0.8	0.2	0.2	0.8	-0.3
Asthma	0.5	0.9	2.2	0.6	0.9	1.1	0.8	1.3	1.3	1.0	0.9	0.5	0.4	1.5	-0.3	0.9	1.4	-0.2	-0.9
Prospective memory result	0.5	0.7	2.2	-1.0	-0.9	-1.5	-0.9	-1.1	-0.7	-0.2	-0.9	-0.8	-0.2	-0.8	-0.7	-0.1	-0.8	-0.7	-0.0
Arm fat mass (right)	0.5	2.2	9.8	0.1	0.5	-1.1	-0.3	1.0	-2.4	-1.5	-3.1	0.0	0.5	-0.9	0.4	1.6	-2.8	-0.1	-1.7
Glaucoma (self-reported)	0.5	0.6	5.5	-0.7	-1.2	-0.5	-0.4	0.0	-0.2	-0.7	2.4	-0.3	-0.3	-0.1	-0.6	-0.8	-0.1	-0.5	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.8	-0.7	0.1	0.4	0.3	-1.0	1.2	-0.7	0.5	-0.8	-0.4	0.1	-1.0	0.3	0.7	-1.1	-1.4
Alcohol intake frequency.	0.5	1.1	2.6	0.9	0.7	0.2	0.8	1.1	-1.2	-0.5	1.4	0.4	1.2	1.0	1.6	0.9	-1.2	1.4	1.0
Comparative height size at age 10	0.5	2.8	6.5	-1.6	-1.9	-2.1	-2.4	-0.6	0.4	-1.0	-2.5	-1.8	-2.1	-1.9	-1.8	-1.6	-0.6	-1.9	-0.1
Suffer from ‘nerves’	0.5	0.8	3.2	0.6	0.4	0.7	1.0	-0.4	1.1	1.5	0.1	1.0	0.2	0.8	-0.3	-0.3	1.5	-0.1	-1.8
Overall health rating	0.5	1.1	3.0	1.4	1.4	-0.0	0.7	0.9	-1.4	-0.1	1.1	1.2	1.1	0.4	1.1	1.7	-0.6	0.8	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	4.5	-0.1	-0.0	0.7	-0.1	-2.1	2.0	0.2	0.4	-0.4	-1.0	-0.1	-1.0	-1.3	1.8	-0.7	-0.8
Breast cancer (self-reported)	0.5	0.6	1.4	1.2	0.9	1.0	0.6	0.8	-0.0	1.0	-0.0	0.5	0.5	0.5	1.1	0.8	0.5	1.1	0.3
Asthma (self-reported)	0.5	1.0	2.5	0.5	0.9	1.4	0.9	1.1	1.4	1.0	1.0	0.7	0.4	1.6	-0.4	0.7	1.5	-0.2	-1.2
Osteoporosis (self-reported)	0.5	0.6	2.3	0.3	0.7	1.5	0.1	0.3	-0.7	-0.7	1.5	0.6	0.5	0.4	0.9	0.9	-0.3	0.7	0.7
Medication: Gliclazide	0.5	0.6	3.2	-0.4	-0.6	0.9	-0.0	0.9	0.6	-0.2	-1.1	-0.0	-0.4	-0.2	-0.9	-0.9	0.2	-0.8	-1.8
Arm fat mass (left)	0.5	2.2	11.8	0.1	0.5	-1.0	-0.3	1.2	-2.3	-1.5	-3.4	0.1	0.5	-0.9	0.4	1.4	-2.8	-0.0	-1.7
Wears glasses or contact lenses	0.5	0.6	1.5	1.1	0.4	1.0	1.2	0.7	0.3	0.2	-0.2	0.4	0.9	1.0	0.8	0.9	0.4	0.9	0.5
Age started oral contraceptive pill	0.5	0.6	2.5	0.5	0.1	-1.4	-0.2	1.6	-0.9	-0.2	-0.6	0.1	0.3	0.1	0.5	-0.0	-1.0	0.6	1.5
Alcohol drinker status: Previous	0.5	0.5	2.7	-0.3	0.9	-0.3	0.5	0.1	1.2	-0.3	1.7	0.3	-0.0	1.2	0.2	0.3	1.0	0.2	0.6
Depressed Affect (Nagel 2018)	0.4	0.9	2.8	-0.3	-0.5	0.4	0.0	-1.0	1.6	1.3	1.4	-0.2	-0.7	0.3	-1.0	-0.7	1.1	-0.9	-1.7
Verbal and Numeric Reasoning (VNR)	0.4	1.1	2.3	-1.5	-1.3	-1.2	-0.7	-0.4	1.4	-0.4	0.4	-1.4	-1.1	-0.6	-1.2	-1.0	1.1	-1.2	-0.1
Body Mass Index (BMI) (2010)	0.4	0.6	2.6	0.0	-0.3	-0.7	-0.6	0.3	-1.3	0.0	0.1	-1.0	0.2	-0.7	0.1	1.2	-1.6	-0.3	-0.6
Ulcerative Colitis	0.4	0.5	2.8	0.1	0.9	0.5	0.5	0.5	1.3	0.9	0.7	0.7	-0.2	0.5	0.0	-0.4	1.7	0.3	0.5
Hypothyroidism (self reported)	0.4	0.9	3.3	0.9	0.5	0.8	0.2	1.8	-1.1	0.7	1.1	0.6	0.6	0.1	1.0	0.6	-0.9	1.0	1.4
Lung FVC	0.4	2.1	7.2	1.8	2.4	0.7	1.3	0.4	-0.2	2.3	0.9	1.4	1.1	1.0	1.6	2.7	0.5	1.5	-0.3
Number of treatments/medications taken	0.4	0.8	3.2	1.1	1.7	0.0	0.3	1.8	-0.3	0.9	-0.6	1.3	0.1	0.3	0.4	1.0	0.3	0.5	-0.7
Ever had hysterectomy (womb removed)	0.4	0.5	2.2	-1.5	-0.4	-0.4	-0.6	-0.6	0.2	0.4	-0.3	-0.1	-0.7	-0.9	-0.4	-1.2	0.3	-0.3	1.0
Pack years adult smoking proportion	0.4	0.6	2.9	0.2	0.1	0.0	-0.5	-1.3	-1.3	-1.2	-0.2	-0.5	0.6	-0.0	0.4	0.3	-1.7	0.2	0.3
Leg fat-free mass (left)	0.4	2.0	5.6	-1.5	-1.7	-1.2	-1.7	-0.6	-0.2	-1.8	-2.4	-1.4	-1.3	-1.5	-1.3	-1.4	-1.3	-1.4	-0.1
Hand grip strength (right)	0.4	1.0	4.9	-2.2	-1.5	-0.1	-0.9	-1.1	0.2	-0.6	-0.8	-0.8	-0.2	-0.3	-1.0	-1.7	-0.2	-0.9	-0.6
Average weekly fortified wine intake	0.4	0.4	2.8	0.1	-0.2	-0.7	-0.4	1.7	0.1	0.6	-1.2	-0.5	-0.2	-0.4	0.1	0.9	0.1	-0.0	-0.3
Body mass index (BMI)	0.4	1.7	6.6	-0.0	0.7	-0.4	0.2	0.7	-2.2	-1.4	-2.6	0.6	0.8	-0.5	0.4	1.3	-2.4	0.1	-1.8
Leg predicted mass (left)	0.4	2.1	5.7	-1.6	-1.7	-1.2	-1.7	-0.7	-0.2	-1.8	-2.4	-1.5	-1.4	-1.5	-1.4	-1.4	-1.3	-1.4	-0.2
Hip circumference	0.4	1.8	8.5	-0.4	0.0	-1.2	-0.7	0.5	-2.0	-1.4	-2.9	-0.2	0.1	-1.0	-0.1	0.9	-2.6	-0.5	-1.8
Father’s age at death	0.4	0.6	2.7	-0.1	-0.3	-0.8	0.5	-1.2	-0.6	-0.1	-1.2	0.2	0.8	0.5	0.7	0.2	-0.4	0.8	1.7
Happiness	0.4	0.5	1.8	0.8	0.7	0.7	0.6	0.3	-0.3	1.0	1.3	0.9	0.5	0.4	0.7	0.6	0.1	0.6	-0.6
Qualifications: A levels/AS levels or equivalent	0.4	0.9	2.8	0.5	-1.1	-0.2	-0.6	0.6	1.3	1.7	1.0	-1.2	-0.9	-0.5	-0.1	-0.7	1.5	-0.1	1.4
Breastfed as a baby	0.4	0.4	1.7	-0.7	1.3	0.4	0.5	-0.6	-0.1	-0.6	-0.5	1.3	0.6	0.5	0.3	0.8	0.5	0.5	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	2.3	-0.2	-0.6	-0.3	0.8	-0.7	1.2	0.9	-0.9	0.2	-0.2	-0.3	-0.8	-0.4	1.4	-0.6	-1.5
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	2.0	1.2	0.8	0.6	0.6	0.4	-0.6	1.4	1.0	0.5	0.5	0.3	0.9	0.9	-0.2	0.8	0.8
Exposure to tobacco smoke outside home	0.4	0.6	3.3	0.5	0.3	1.1	0.7	0.8	0.2	-0.3	1.4	0.8	0.2	0.5	0.0	0.5	0.2	-0.1	-1.8
Knee pain experienced in last month	0.4	0.6	1.4	0.1	0.7	1.1	0.7	-1.1	-1.0	-1.1	1.2	1.0	0.5	-0.1	0.2	0.6	-0.7	0.2	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	2.7	-0.6	-0.7	-0.4	-0.6	-1.6	-0.5	-0.3	-0.6	-0.9	-0.2	-0.5	-0.3	-0.7	-1.0	-0.4	-0.1
Illnesses of siblings: Diabetes	0.4	0.5	2.0	0.1	0.4	0.1	0.1	0.7	-1.4	0.2	0.1	0.7	0.7	-0.2	0.8	1.0	-0.8	0.7	0.7
Leg fat-free mass (right)	0.4	2.4	6.6	-1.6	-1.8	-1.2	-1.9	-0.5	0.1	-1.9	-2.6	-1.6	-1.6	-1.8	-1.5	-1.5	-1.2	-1.5	-0.2
Average weekly red wine intake	0.4	0.6	3.5	-1.9	-1.0	-0.5	-0.0	0.5	-0.4	-1.4	-0.5	-0.5	-0.1	-0.4	-0.6	-0.4	-0.7	-0.7	0.0
Friendships satisfaction	0.4	0.5	2.1	-0.1	-0.4	0.1	-0.2	-0.7	0.8	-1.1	1.2	-0.2	-0.5	-0.0	-0.6	0.1	0.7	-0.6	-1.4
Leg predicted mass (right)	0.4	2.3	6.4	-1.6	-1.8	-1.2	-1.9	-0.5	-0.0	-1.8	-2.5	-1.6	-1.6	-1.8	-1.4	-1.5	-1.2	-1.4	-0.1
Irritability	0.4	0.6	2.5	-0.2	0.1	0.2	-0.2	-1.2	1.1	0.5	-0.8	-0.6	-0.7	0.1	-0.7	1.0	0.6	-0.9	-1.6
Commuting to job workplace: Cycle	0.4	0.5	1.5	1.0	0.7	-0.1	0.3	-0.1	0.9	-0.1	0.5	0.1	0.4	1.2	0.6	0.4	1.0	0.8	0.9
Heart disease (siblings)	0.4	0.5	1.1	0.9	1.0	0.2	0.9	1.0	0.7	-0.2	0.5	0.9	0.4	0.9	0.6	0.6	0.8	0.8	0.4
Bipolar Disorder (2018)	0.3	0.5	3.2	0.4	0.8	0.2	0.9	-0.9	0.4	0.4	-0.6	0.6	0.4	0.5	-0.4	0.7	0.3	-0.3	-1.8
Alzheimer’s Disease (in mother)	0.3	0.3	1.8	0.3	0.3	0.5	0.0	1.3	0.2	-0.5	0.7	0.3	0.2	0.6	-0.4	0.6	0.3	-0.3	-1.0
Crohns Disease (2017)	0.3	0.7	3.1	-0.4	0.4	1.2	0.2	-0.3	1.2	-0.5	0.4	0.3	-0.7	-0.2	-0.7	0.0	1.4	-0.9	-1.8
Breast Cancer	0.3	0.7	2.2	-0.7	-0.5	1.0	-0.2	-0.6	1.3	-0.8	-0.6	-0.1	-0.9	-0.1	-1.2	-1.0	0.7	-1.0	-1.5
Bipolar Disorder (2011)	0.3	0.3	1.9	0.1	-0.1	-0.5	-0.2	-1.4	-0.1	0.7	0.9	-0.5	0.0	-0.0	0.2	-0.3	0.1	0.1	0.5
Coronary Artery Disease (CAD)	0.3	0.4	1.8	0.7	0.3	0.1	0.5	0.9	-0.7	-0.5	1.3	0.0	0.5	0.2	0.6	-0.5	-0.2	0.5	0.9
HDL Cholesterol	0.3	0.4	1.9	-0.0	0.1	1.4	0.1	0.5	0.5	0.7	1.4	0.4	-0.2	0.2	-0.5	-0.3	0.1	-0.4	-1.2
Average weekly spirits intake	0.3	0.4	1.2	1.1	0.6	-0.2	0.3	0.6	-0.9	0.2	-0.5	1.1	0.5	0.4	0.6	0.4	-0.4	0.6	-0.7
Taking other prescription medications	0.3	0.4	1.9	0.4	0.5	-0.5	-0.6	0.7	0.2	0.8	0.1	0.1	-0.8	-0.8	-0.6	0.4	0.5	-0.7	-1.4
Age when periods started (menarche)	0.3	0.6	3.2	-0.0	-0.0	0.7	0.1	-0.3	1.3	0.9	0.4	-0.1	-0.5	0.3	0.0	-0.9	1.4	0.3	1.8
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.2	1.4	1.3	0.2	0.5	-0.2	0.1	-0.1	1.2	0.6	0.2	0.6	0.4	1.5	0.4	0.4	0.2
Qualifications: None of the above	0.3	0.7	3.1	-1.3	0.0	-0.3	-0.7	-1.8	-0.5	-1.1	0.7	-0.1	-0.2	-0.3	-0.8	-0.1	-0.5	-0.9	-1.3
Diabetes (self-reported)	0.3	0.5	2.0	-0.7	-0.8	0.1	0.0	-0.2	-1.3	-0.8	0.1	0.0	0.4	-0.8	0.7	-0.5	-1.1	0.7	1.4
Medication: Simvastatin	0.3	0.5	3.4	0.2	0.9	-0.7	0.0	1.8	-0.5	1.1	0.2	0.5	0.4	0.2	0.5	0.7	-0.5	0.4	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	1.5	0.1	-0.6	-0.9	-0.2	-0.8	-1.0	0.6	0.6	0.0	-0.2	-1.2	0.5	0.6	-1.0	0.2	0.0
Medication: Cholesterol lowering	0.3	0.5	2.0	0.1	1.0	-0.5	1.0	1.4	-0.0	0.7	-0.2	1.2	0.6	0.5	0.6	0.1	0.4	0.8	0.7
Medication: Paracetamol	0.3	0.5	1.6	-0.5	-0.2	-0.1	-0.8	-1.1	0.2	-1.3	0.5	-0.8	-0.8	-0.7	-1.0	-0.4	-0.2	-1.0	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.6	0.0	-0.4	0.7	0.9	-1.3	0.1	0.5	0.8	0.5	0.7	0.9	0.3	0.3	0.0	0.2	-0.4
Pulse wave peak to peak time	0.3	0.3	0.9	-0.6	-0.6	0.9	-0.5	-0.5	0.9	0.1	-0.5	-0.8	-0.6	-0.2	-0.2	-0.9	0.7	-0.1	0.5
Eye problems/disorders: None of the above	0.3	0.4	2.6	-0.3	0.1	0.2	-0.0	-1.6	0.6	-0.7	-1.0	-0.1	-0.4	-0.3	-0.6	0.2	0.6	-0.6	-0.8
Heart disease (mother)	0.3	0.3	1.3	-1.2	-0.5	-0.4	-0.4	0.4	-0.7	-0.1	-0.0	-0.7	-0.1	-0.8	-0.2	-1.1	-0.6	-0.3	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	3.0	-0.8	-0.7	0.8	0.0	-0.7	-0.6	-0.2	1.7	-0.3	0.4	-0.2	0.2	0.1	-0.6	0.1	0.2
Diabetes diagnosed by doctor	0.3	0.6	1.8	-0.5	-0.6	0.2	0.2	0.0	-1.4	-1.0	0.5	0.3	0.6	-0.4	0.8	-0.3	-1.4	0.7	1.4
Eye problems/disorders: Cataract	0.3	0.4	3.2	-0.5	-0.3	-0.6	-0.4	1.8	0.0	0.8	-0.8	-0.4	-0.2	-0.2	-0.2	-0.8	-0.1	-0.1	-0.2
Osteoarthritis (self-reported)	0.3	0.4	2.1	0.3	0.5	0.1	0.1	0.2	0.5	-1.3	1.0	0.3	-0.1	0.2	-0.3	0.2	0.4	-0.3	-1.4
Miserableness	0.3	0.6	2.1	-0.4	-0.5	0.3	0.2	-0.1	1.2	1.4	1.4	-0.1	-0.4	0.3	-0.8	-0.5	1.0	-0.6	-1.0
Financial situation satisfaction	0.3	0.3	1.6	-0.0	0.3	-0.0	-0.1	-0.4	0.7	0.5	0.7	-0.1	-0.4	-0.3	-0.7	-0.4	0.6	-0.7	-1.2
Commuting to job workplace: Public transport	0.3	0.4	4.0	0.6	0.8	0.2	0.2	2.0	-0.1	0.4	0.2	0.6	0.3	0.3	0.1	0.4	0.4	0.2	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.4	-0.7	-0.0	-0.1	-0.4	-0.8	0.0	-1.2	-0.0	-0.2	-0.3	-0.3	-0.6	-0.6	-0.3	-0.6	-0.9
Pain experienced in last month	0.3	0.6	2.2	-0.6	-1.2	-0.2	-0.9	0.4	0.9	-0.2	-0.5	-0.9	-0.9	-0.4	-0.7	-1.5	0.2	-0.6	-0.2
Basal cell carcinoma (self-reported)	0.3	0.4	1.1	0.0	-0.5	-0.7	-0.7	-0.5	0.7	-0.1	-0.5	-0.8	-1.0	-0.6	-0.1	-0.5	0.2	-0.1	1.1
Pack years of smoking	0.3	0.5	1.9	0.6	0.5	0.3	-0.1	-0.8	-1.2	-1.4	-0.1	-0.0	0.8	0.4	0.5	0.4	-1.4	0.4	0.1
Impedance of whole body	0.3	1.5	5.4	2.3	1.8	-0.2	0.7	1.0	-0.1	2.0	0.8	0.8	0.5	0.8	1.1	2.1	0.4	0.9	-0.1
Crohns Disease (2012)	0.2	0.4	2.0	-0.4	-0.1	-0.1	0.1	-0.3	1.2	0.1	-0.0	-0.1	-0.8	-0.5	-0.8	-0.3	1.4	-0.8	-0.3
Rheumatoid Arthritis	0.2	0.3	1.1	0.7	0.3	1.0	-0.2	0.5	1.1	-0.3	0.5	0.2	-0.8	0.1	-0.1	-0.4	1.0	0.0	-0.5
BMI	0.2	1.4	6.1	-0.2	0.9	-0.2	-0.0	0.7	-2.5	-1.0	-1.7	1.0	1.0	-0.3	1.0	1.0	-2.3	0.7	-0.9
Waist Hip Ratio (WHR)	0.2	1.0	3.6	1.4	1.0	-0.4	0.8	0.5	-0.8	1.9	-0.4	0.7	1.2	0.8	1.2	1.4	-0.4	1.1	0.5
Chronotype (morning person)	0.2	0.4	1.0	0.9	0.6	-0.1	0.5	-0.9	0.8	-0.6	-0.0	0.6	-0.3	0.3	-0.3	0.3	1.0	-0.1	-0.8
Townsend deprivation index at recruitment	0.2	0.3	3.1	0.3	0.6	-0.0	0.2	0.1	0.2	-0.3	0.1	0.6	-0.2	-0.1	-0.3	0.5	-0.2	-0.4	-1.7
Fed-up feelings	0.2	0.3	1.8	0.3	0.1	1.0	-0.2	-0.8	0.3	0.9	0.6	-0.2	-0.3	0.0	-0.3	0.4	0.2	-0.5	-1.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.0	-0.1	0.2	-0.7	0.2	-0.9	0.0	-0.5	-1.0	0.1	0.2	0.2	0.1	-0.4	0.2	0.1	0.7
Heart attack	0.2	0.3	0.6	-0.7	-0.1	-0.8	-0.6	-0.5	0.1	0.6	-0.4	0.0	-0.6	-0.5	-0.8	-0.6	-0.0	-0.7	-0.8
Allergy	0.2	0.5	1.3	-0.5	-0.7	-0.1	0.4	0.2	-1.2	0.3	-1.1	0.3	0.7	-0.3	0.8	-0.8	-1.1	0.8	1.1
Fluid intelligence score	0.2	0.5	2.4	0.3	-0.4	0.0	0.0	0.5	1.6	0.3	-0.2	-0.7	-0.7	0.0	-0.2	-1.0	1.5	-0.1	0.5
Number of live births	0.2	0.3	1.5	-0.7	-0.5	-0.6	0.3	0.4	-0.5	-1.2	0.9	-0.3	0.5	0.2	0.1	-0.2	-0.5	-0.0	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.1	-0.3	0.0	0.7	-0.1	-0.6	0.7	0.4	1.1	0.2	-0.4	-0.1	-0.6	-0.5	0.6	-0.4	-0.1
Illnesses of mother	0.2	0.3	1.0	-0.4	-0.4	0.6	-0.5	-1.0	0.3	-0.4	-0.2	-0.3	-0.8	-0.4	-0.5	-0.6	0.1	-0.5	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	2.3	0.8	1.2	0.3	0.4	-0.8	-0.2	1.5	0.0	0.6	0.6	0.8	1.0	0.7	-0.1	1.0	0.5
Pulse wave Arterial Stiffness index	0.2	0.3	1.3	0.4	0.4	-1.1	0.3	0.2	-0.7	-0.4	0.2	0.6	0.3	0.1	-0.0	0.7	-0.6	-0.1	-0.5
Tense / ‘highly strung’	0.2	0.3	1.5	0.4	0.0	-0.1	0.6	-1.2	0.2	0.6	0.1	0.2	0.3	0.6	0.2	1.0	-0.0	0.0	-1.0
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	1.2	0.3	0.1	-0.1	0.1	0.8	-1.1	-0.3	-0.0	0.3	0.2	-0.5	0.4	0.6	-1.1	0.4	0.9
Chronic bronchitis/emphysema (mother)	0.2	0.2	1.4	0.8	0.0	0.1	-0.1	-1.2	-0.5	0.4	0.3	-0.1	0.2	-0.2	0.3	-0.1	-0.5	0.3	0.6
Number of children fathered	0.2	0.2	1.1	-0.2	-1.0	0.4	-0.2	-0.3	0.1	-0.4	-0.5	-0.6	0.0	0.3	-0.6	-0.3	0.0	-0.6	-0.8
Health satisfaction	0.2	0.2	1.7	-0.1	0.5	-0.5	0.1	-0.1	0.1	-0.1	-0.1	0.8	-0.2	-0.1	-0.4	-0.2	0.3	-0.4	-1.3
Shortness of breath walking on level ground	0.2	0.2	0.9	0.1	0.5	-0.6	0.1	0.4	0.8	0.1	-0.2	0.5	-0.2	0.0	-0.3	0.1	1.0	-0.2	-0.7
Pulse rate, automated reading	0.2	0.5	4.8	-0.7	0.0	0.3	0.2	-1.0	0.3	0.4	0.1	-0.2	0.2	0.5	-0.8	-0.2	-0.1	-0.9	-2.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.6	-0.5	0.4	0.8	-0.2	-0.4	0.6	-0.3	-0.7	-0.0	-0.2	0.2	-0.4	-0.5	0.7	-0.2	-0.0
Qualifications: nursing, teaching	0.2	0.4	1.3	0.5	-0.8	-0.0	-0.4	0.1	-0.9	0.8	1.1	-0.1	0.1	-0.5	0.4	0.6	-0.9	0.3	0.4
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.8	-0.9	-0.1	-0.3	-0.3	-0.5	-0.4	-0.2	0.1	-0.2	-0.4	-0.7	-0.8	-0.1	-0.4	-0.9	-0.9
Medication: Paracetamol	0.2	0.3	2.5	0.1	0.1	-0.1	-0.4	-0.9	-0.2	-1.6	0.5	-0.5	-0.2	-0.2	-0.4	0.3	-0.5	-0.5	-0.1
Risk taking	0.2	0.3	1.6	0.7	0.6	0.7	-0.1	0.2	-0.2	0.5	0.8	-0.1	0.2	0.3	0.1	1.3	-0.3	-0.1	-0.8
Supplements: Calcium	0.2	0.2	0.8	0.2	-0.0	-0.7	-0.9	0.1	-0.0	-0.3	0.6	-0.5	-0.5	-0.5	-0.0	0.3	0.2	-0.2	0.5
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.9	-0.5	0.1	-0.6	-0.4	-0.5	0.1	0.7	-0.5	0.2	-0.4	-0.4	-0.7	-0.6	0.1	-0.6	-0.9
HbA1C	0.1	0.1	0.3	0.0	0.6	-0.4	0.1	-0.5	0.1	0.2	0.4	0.1	-0.4	0.3	0.5	0.4	0.0	0.5	-0.1
Neuroticism (2016)	0.1	0.1	0.6	0.5	-0.1	-0.1	0.2	-0.2	0.7	0.1	-0.4	-0.3	-0.2	-0.1	-0.0	0.2	0.8	-0.1	-0.6
Blood Eosinophil Count	0.1	0.8	2.1	-0.1	-0.5	-1.2	-0.8	-1.0	-1.2	-1.3	0.2	-0.1	-0.3	-1.0	-1.0	-0.6	-1.5	-1.1	-1.0
Blood White Count	0.1	0.4	2.8	0.1	-0.2	-1.0	-0.2	0.4	-0.3	-0.1	1.7	-0.5	0.0	-0.3	0.0	0.3	-0.5	-0.0	1.2
Allergy or Eczema	0.1	0.2	0.9	0.5	0.4	-0.5	-0.3	-0.6	0.3	-0.6	1.0	-0.3	-0.6	-0.3	-0.4	0.6	0.2	-0.4	0.2
Hair Pigment	0.1	2.0	8.4	0.4	1.0	2.2	1.6	0.8	-1.1	2.4	0.5	2.9	1.4	1.1	0.9	-0.6	-0.4	1.2	-1.0
Tanning	0.1	1.1	6.0	-1.5	-0.7	-1.6	-0.8	-0.4	-0.7	-2.4	-1.1	-0.6	-0.4	-1.0	-0.6	-0.1	-1.2	-0.6	0.5
Vitamin and mineral supplements	0.1	0.1	0.8	-0.8	-0.9	-0.1	-0.2	-0.2	0.0	-0.2	0.2	-0.4	-0.1	0.0	-0.3	-0.5	-0.2	-0.3	0.1
Impedance of leg (right)	0.1	0.3	1.6	-0.1	0.0	-0.5	-0.1	-1.3	0.1	1.2	0.0	0.1	-0.2	0.0	-0.4	-0.6	0.5	-0.4	-0.7
Multivitamins +/- minerals	0.1	0.2	0.5	0.0	0.4	-0.0	-0.3	-0.5	0.4	-0.2	0.6	-0.4	-0.5	-0.7	-0.5	0.3	0.2	-0.5	-0.5
Impedance of leg (left)	0.1	0.5	1.4	-0.3	-0.2	-0.7	-0.5	-0.9	0.3	1.0	-0.8	-0.3	-0.7	-0.6	-0.8	-0.8	0.5	-0.8	-1.2
Number of incorrect matches in round	0.1	0.2	1.2	-0.4	-0.3	0.4	-0.3	-0.8	-0.3	-0.7	-0.5	-0.1	-0.2	-0.3	0.0	-1.1	-0.2	0.1	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.7	0.7	-0.1	0.2	-0.0	-0.1	0.1	0.7	0.4	-0.5	-0.2	-0.2	0.0	0.8	-0.5	-0.2	-0.8
Forced vital capacity (FVC)	0.1	0.4	4.2	0.3	0.6	0.4	-0.2	-0.1	0.1	2.1	0.7	-0.2	0.2	0.5	0.6	0.6	0.1	0.5	0.6
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.4	0.3	-0.2	-0.1	-0.5	0.1	0.1	0.3	-0.6	-0.6	-0.3	-0.2	-0.1	0.5	0.0	-0.4	-0.6
Illnesses of siblings	0.1	0.1	1.0	0.7	0.2	-0.6	0.0	0.1	0.1	0.0	-1.0	-0.2	-0.1	-0.2	-0.1	-0.1	-0.2	-0.1	0.0
Pulse wave reflection index	0.1	0.2	0.7	0.5	-0.1	-0.5	0.0	0.6	-0.4	-0.1	0.3	0.3	-0.3	-0.4	0.4	0.3	-0.1	0.4	0.8
Headache pain in last month	0.1	0.2	1.2	1.1	0.7	0.1	0.2	-0.5	0.4	0.2	-0.2	0.0	0.1	0.6	0.3	0.8	0.4	0.3	0.2
Forced vital capacity (FVC), Best measure	0.1	0.4	2.8	-0.0	0.7	-0.1	-0.4	-1.0	0.7	1.7	-0.1	-0.4	-0.3	0.3	0.1	0.1	0.5	0.2	0.5
Medication for pain relief, constipation, heartburn	0.1	0.1	0.5	0.4	-0.6	0.0	-0.1	-0.7	-0.0	0.5	0.7	-0.4	0.1	0.1	0.3	0.4	0.1	0.1	-0.1
Medication: Ibuprofen	0.1	0.2	0.5	-0.2	-0.0	0.5	-0.7	-0.4	-0.7	-0.4	0.7	0.2	-0.1	-0.3	0.0	-0.1	-0.7	0.0	0.3
Medication: Omeprazole	0.1	0.1	1.2	-0.3	0.2	0.3	0.1	-0.3	-0.1	-1.1	0.1	-0.1	0.3	0.3	-0.2	-0.2	-0.3	-0.2	-0.5
Medication: Seretide 50 evohaler	0.1	0.2	0.8	0.4	0.9	0.2	0.1	0.9	-0.2	0.6	0.1	0.3	-0.1	-0.2	0.2	0.2	0.0	0.2	0.2
Back pain experienced in last month	0.1	0.2	1.2	-0.0	0.8	0.4	0.1	0.1	0.1	1.1	0.6	0.3	-0.1	-0.1	-0.3	0.7	0.3	-0.4	-0.3

Hub : Genes

SAV1

Models

Trait associations