[Hub]/) : Traits : Sitting height :

chr14:75,343,027-77,117,550

Best TWAS P=1.97e-12 · Best GWAS P=2.61e-11 conditioned to 0.164

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TTLL5 0.13 0.15 lasso 10 0.19 1.2e-22 5.3 -6.4 2.1e-10 -0.82 0.72 0.28 FALSE
2 GTEx Adipose Subcutaneous TTLL5 0.13 0.10 lasso 4 0.11 2.2e-09 5.4 -5.9 3.8e-09 -0.73 0.52 0.48 FALSE
3 GTEx Artery Aorta TTLL5 0.09 0.11 lasso 3 0.07 1.1e-04 5.8 -6.0 2.7e-09 -0.62 0.47 0.40 FALSE
4 GTEx Artery Tibial TTLL5 0.09 0.05 lasso 4 0.05 1.3e-04 5.0 -5.4 8.3e-08 -0.70 0.69 0.21 FALSE
5 GTEx Brain Cerebellar Hemisphere TTLL5 0.19 0.06 lasso 2 0.02 9.7e-02 5.7 -5.8 6.3e-09 -0.48 0.10 0.35 FALSE
6 GTEx Brain Cortex TTLL5 0.23 0.09 lasso 13 0.07 5.9e-03 6.6 -7.0 2.5e-12 -0.91 0.04 0.85 FALSE
7 GTEx Cells Transformed fibroblasts TTLL5 0.09 0.09 lasso 6 0.11 1.6e-08 5.3 -5.7 1.0e-08 -0.82 0.52 0.48 FALSE
8 GTEx Cells Transformed fibroblasts FLVCR2 0.21 0.16 lasso 8 0.17 1.2e-12 6.3 6.2 6.3e-10 0.89 0.06 0.94 FALSE
9 GTEx Cells Transformed fibroblasts AC007182.6 0.18 0.20 lasso 7 0.18 2.1e-13 6.3 6.3 3.1e-10 0.89 0.08 0.92 FALSE
10 GTEx Esophagus Gastroesophageal Junction TTLL5 0.16 0.03 lasso 3 0.01 1.2e-01 5.2 -5.3 1.2e-07 -0.75 0.13 0.63 FALSE
11 GTEx Esophagus Mucosa TTLL5 0.11 0.00 lasso 5 0.00 2.4e-01 5.1 -5.5 4.5e-08 -0.74 0.22 0.43 FALSE
12 GTEx Lung TTLL5 0.15 0.08 enet 17 0.11 9.0e-09 5.4 -5.9 4.8e-09 -0.74 0.72 0.28 FALSE
13 METSIM Adipose TTLL5 0.12 0.01 blup 624 0.05 2.1e-07 4.8 -5.4 5.7e-08 -0.53 0.36 0.37 FALSE
14 YFS Blood TTLL5 0.04 0.04 lasso 6 0.03 1.4e-10 4.4 -5.5 2.9e-08 -0.54 0.99 0.01 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma TTLL5 0.01 0.02 enet 7 0.02 3.6e-05 5.8 -7.0 3.2e-12 -0.80 0.04 0.87 FALSE
16 The Cancer Genome Atlas Colon Adenocarcinoma TTLL5 0.07 0.04 blup 121 0.06 2.4e-04 6.6 -6.4 2.1e-10 -0.92 0.03 0.96 FALSE
17 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TTLL5 0.04 0.02 blup 121 0.04 1.1e-05 5.9 -6.3 2.7e-10 -0.79 0.24 0.75 FALSE
18 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TTLL5 0.04 0.03 blup 121 0.04 2.8e-05 5.0 -5.9 3.5e-09 -0.73 0.69 0.24 FALSE
19 The Cancer Genome Atlas Lung Adenocarcinoma TTLL5 0.03 0.01 blup 122 0.02 3.2e-03 5.7 -7.0 2.0e-12 -0.84 0.05 0.88 TRUE
20 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TTLL5 0.02 0.01 blup 121 0.02 2.5e-03 5.7 -6.9 4.4e-12 -0.86 0.05 0.58 FALSE
21 The Cancer Genome Atlas Prostate Adenocarcinoma TTLL5 0.03 0.03 lasso 3 0.02 1.6e-03 4.9 -5.2 2.4e-07 -0.62 0.06 0.69 FALSE
22 The Cancer Genome Atlas Thyroid Carcinoma TTLL5 0.06 0.05 blup 121 0.05 6.3e-06 4.7 -6.0 1.8e-09 -0.79 0.92 0.08 FALSE