Best TWAS P=2.76e-10 · Best GWAS P=1.57e-06 conditioned to 0.69
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | RP11-347C12.1 | 0.06 | 0.02 | bslmm | 209 | 0.04 | 4.3e-07 | -2.8 | -5.5 | 4.3e-08 | -0.02 | 0.39 | 0.21 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | YPEL3 | 0.06 | 0.03 | blup | 209 | 0.04 | 1.9e-05 | 3.9 | 5.6 | 1.9e-08 | 0.71 | 0.12 | 0.78 | FALSE |
| 3 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | YPEL3 | 0.15 | 0.00 | blup | 20 | 0.05 | 2.9e-03 | 4.7 | 6.3 | 2.8e-10 | 0.80 | 0.00 | 0.19 | TRUE |