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chr17:52,287,259-53,940,001

Best TWAS P=7.32e-09 · Best GWAS P=1.7e-08 conditioned to 0.0856

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	STXBP4	0.19	0.15	lasso	9	0.15	4.5e-12	-5.360	5.7	1.2e-08	-0.86	0.03	0.97	FALSE
2	GTEx	Adipose Visceral Omentum	STXBP4	0.14	0.14	enet	9	0.14	6.8e-08	-5.192	5.3	1.0e-07	-0.87	0.03	0.97	FALSE
3	GTEx	Artery Tibial	STXBP4	0.30	0.23	enet	11	0.24	4.2e-19	-5.476	5.5	3.3e-08	-0.88	0.01	0.99	FALSE
4	GTEx	Breast Mammary Tissue	STXBP4	0.18	0.10	lasso	3	0.08	6.1e-05	-5.476	5.8	7.3e-09	-0.80	0.02	0.96	TRUE
5	GTEx	Breast Mammary Tissue (Male)	STXBP4	0.20	0.01	lasso	5	0.01	1.5e-01	-5.192	5.3	1.4e-07	-0.84	0.04	0.56	FALSE
6	GTEx	Breast Mammary Tissue (Male)	CTC-462L7.1	0.16	0.01	lasso	2	-0.01	6.0e-01	-0.041	5.5	4.3e-08	-0.90	0.04	0.40	FALSE
7	GTEx	Cells Transformed fibroblasts	STXBP4	0.16	0.12	lasso	6	0.11	1.2e-08	-5.192	5.3	1.3e-07	-0.87	0.03	0.97	FALSE
8	GTEx	Cells Transformed fibroblasts	CTC-462L7.1	0.13	0.13	lasso	4	0.12	4.7e-09	-5.476	5.5	3.4e-08	-0.91	0.02	0.98	FALSE
9	GTEx	Lung	STXBP4	0.13	0.05	enet	15	0.07	4.1e-06	-5.360	5.2	1.9e-07	-0.79	0.02	0.98	FALSE
10	GTEx	Nerve Tibial	COX11	0.13	0.07	lasso	5	0.08	3.9e-06	-5.476	5.7	1.6e-08	-0.84	0.02	0.98	FALSE
11	GTEx	Nerve Tibial	STXBP4	0.29	0.22	enet	31	0.22	2.4e-15	-5.476	5.6	2.2e-08	-0.93	0.02	0.98	FALSE
12	GTEx	Nerve Tibial	CTC-462L7.1	0.14	0.15	lasso	6	0.14	6.9e-10	-5.476	5.3	1.1e-07	-0.89	0.01	0.98	FALSE
13	GTEx	Pituitary	TOM1L1	0.25	0.02	lasso	2	0.03	7.3e-02	-5.324	5.4	7.5e-08	-0.95	0.03	0.66	FALSE
14	GTEx	Skin Sun Exposed Lower leg	STXBP4	0.09	0.06	lasso	2	0.04	1.8e-04	-5.360	5.3	9.7e-08	-0.83	0.03	0.96	FALSE
15	GTEx	Testis	TOM1L1	0.17	0.12	lasso	7	0.08	1.5e-04	-5.498	5.6	2.6e-08	-1.00	0.01	0.98	FALSE
16	GTEx	Thyroid	STXBP4	0.24	0.18	lasso	9	0.16	1.2e-12	-5.476	5.5	4.6e-08	-0.91	0.01	0.99	FALSE
17	YFS	Blood	COX11	0.15	0.19	lasso	7	0.22	2.1e-68	-5.640	5.2	1.6e-07	-0.94	0.01	0.99	FALSE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	STXBP4	0.03	0.03	lasso	1	0.02	1.9e-03	-5.192	5.2	2.1e-07	-0.84	0.03	0.84	FALSE
19	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TOM1L1	0.12	0.08	blup	91	0.08	1.8e-05	-5.640	5.6	2.1e-08	-0.91	0.01	0.99	FALSE