Best TWAS P=6.32e-11 · Best GWAS P=1.19e-09 conditioned to 0.429
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | UTP18 | 0.15 | 0.07 | lasso | 4 | 0.07 | 5.1e-04 | -4.8 | -5.5 | 3.0e-08 | -0.63 | 0.27 | 0.57 | FALSE |
| 2 | The Cancer Genome Atlas | Glioblastoma Multiforme | NME1-NME2 | 0.08 | 0.10 | enet | 7 | 0.06 | 6.9e-03 | 5.4 | 5.8 | 6.5e-09 | 0.86 | 0.01 | 0.83 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | NME1-NME2 | 0.09 | 0.08 | enet | 5 | 0.08 | 2.5e-05 | 6.1 | 6.5 | 6.3e-11 | 0.87 | 0.00 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | NME2 | 0.08 | 0.04 | lasso | 3 | 0.06 | 1.5e-04 | -4.5 | -5.2 | 1.9e-07 | -0.67 | 0.26 | 0.45 | FALSE |
| 5 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | NME1-NME2 | 0.11 | 0.04 | blup | 43 | 0.08 | 9.0e-05 | 5.5 | 5.1 | 3.1e-07 | 0.73 | 0.04 | 0.95 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NME1-NME2 | 0.14 | 0.16 | blup | 43 | 0.21 | 1.3e-21 | 4.0 | 5.4 | 5.7e-08 | 0.79 | 0.87 | 0.12 | FALSE |
| 7 | The Cancer Genome Atlas | Stomach Adenocarcinoma | NME1-NME2 | 0.07 | 0.03 | blup | 43 | 0.05 | 2.0e-04 | 5.4 | 5.3 | 1.3e-07 | 0.80 | 0.01 | 0.96 | FALSE |