Best TWAS P=2.21e-17 · Best GWAS P=1.62e-20 conditioned to 3.37e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | TGFB2 | 0.14 | 0.07 | lasso | 2 | 0.06 | 2.8e-05 | 5.4 | 5.4 | 5.4e-08 | 0.24 | 0.82 | 0.01 | FALSE |
| 2 | The Cancer Genome Atlas | Soft Tissue Sarcoma | TGFB2 | 0.05 | 0.03 | blup | 73 | 0.03 | 4.5e-03 | 7.9 | -7.2 | 4.2e-13 | -0.90 | 0.01 | 0.89 | FALSE |
| 3 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | TGFB2 | 0.24 | 0.11 | enet | 10 | 0.14 | 1.4e-04 | 7.7 | -8.5 | 2.2e-17 | -0.80 | 0.08 | 0.63 | TRUE |