[Hub]/) : Traits : Sitting height :

chr1:226,488,826-228,989,201

Best TWAS P=3.55e-24 · Best GWAS P=5.21e-25 conditioned to 0.741

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex JMJD4 0.10 0.05 bslmm 381 0.04 6.8e-06 -10.2 -8.6 6.0e-18 0.84 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex LOC100130093 0.09 0.07 enet 30 0.10 5.6e-12 6.4 5.3 1.4e-07 -0.19 1.00 0.00 FALSE
3 CommonMind Brain Pre-frontal Cortex SNAP47 0.23 0.19 lasso 7 0.19 5.7e-23 -7.6 7.5 8.2e-14 -0.60 1.00 0.00 FALSE
4 GTEx Adipose Subcutaneous SNAP47 0.06 0.06 lasso 3 0.05 4.5e-05 -6.4 7.4 1.9e-13 -0.50 0.35 0.25 FALSE
5 GTEx Brain Cortex SNAP47 0.21 0.05 lasso 9 0.04 2.2e-02 -7.4 10.1 3.5e-24 -0.88 0.03 0.79 TRUE
6 GTEx Breast Mammary Tissue (Male) CDC42BPA 0.03 0.01 enet 1 0.00 3.0e-01 6.5 -6.5 1.0e-10 0.18 0.05 0.06 FALSE
7 GTEx Cells EBV-transformed lymphocytes JMJD4 0.13 0.06 lasso 4 0.03 2.9e-02 -9.7 -9.5 3.2e-21 0.50 0.05 0.45 TRUE
8 GTEx Muscle Skeletal SNAP47 0.09 0.08 lasso 10 0.08 7.7e-08 -7.6 9.0 2.4e-19 -0.60 0.97 0.03 FALSE
9 GTEx Nerve Tibial SNAP47 0.06 0.01 enet 16 0.03 6.5e-03 -8.7 8.2 3.1e-16 -0.64 0.04 0.87 FALSE
10 GTEx Skin Not Sun Exposed Suprapubic CDC42BPA 0.13 0.00 enet 30 0.03 8.6e-03 -7.4 -7.6 2.8e-14 0.45 0.12 0.50 FALSE
11 GTEx Testis SNAP47 0.23 0.21 enet 15 0.21 7.5e-10 -7.4 6.4 1.2e-10 -0.46 0.99 0.00 FALSE
12 GTEx Thyroid C1orf35 0.10 0.00 lasso 6 0.01 4.1e-02 5.4 -7.4 1.0e-13 0.37 0.05 0.07 FALSE
13 METSIM Adipose SNAP47 0.06 0.06 lasso 6 0.08 2.0e-11 -8.7 8.8 1.1e-18 -0.76 0.95 0.05 FALSE
14 YFS Blood JMJD4 0.11 0.12 lasso 4 0.12 3.7e-36 -8.7 -8.8 1.5e-18 0.80 1.00 0.00 FALSE
15 YFS Blood SNAP47 0.02 0.00 bslmm 403 0.01 6.4e-04 -7.0 8.4 3.6e-17 -0.45 0.11 0.23 FALSE
16 The Cancer Genome Atlas Breast Invasive Carcinoma LOC100130093 0.02 0.01 lasso 4 0.01 4.0e-03 6.6 5.2 2.5e-07 -0.28 0.10 0.02 FALSE
17 The Cancer Genome Atlas Colon Adenocarcinoma SNAP47 0.05 0.05 lasso 3 0.06 2.4e-04 -7.4 9.6 8.0e-22 -0.81 0.01 0.90 FALSE
18 The Cancer Genome Atlas Brain Lower Grade Glioma JMJD4 0.07 0.01 enet 9 0.03 3.6e-04 -10.2 -5.4 7.5e-08 0.66 0.00 0.80 FALSE
19 The Cancer Genome Atlas Brain Lower Grade Glioma SNAP47 0.08 0.06 blup 54 0.08 1.2e-09 -7.4 7.1 1.0e-12 -0.56 0.97 0.03 FALSE
20 The Cancer Genome Atlas Liver Hepatocellular Carcinoma SNAP47 0.07 0.05 blup 54 0.05 2.9e-03 -7.4 8.4 4.2e-17 -0.65 0.02 0.37 FALSE
21 The Cancer Genome Atlas Lung Adenocarcinoma SNAP47 0.03 0.02 enet 4 0.02 1.5e-03 -7.4 7.4 1.2e-13 -0.52 0.40 0.15 FALSE
22 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LOC100130093 0.16 0.10 blup 42 0.05 4.7e-03 6.8 7.8 8.7e-15 -0.57 0.22 0.25 FALSE
23 The Cancer Genome Atlas Prostate Adenocarcinoma ARF1 0.06 0.02 blup 31 0.03 1.0e-03 -3.6 -6.8 9.8e-12 0.14 0.18 0.71 TRUE
24 The Cancer Genome Atlas Prostate Adenocarcinoma ZNF678 0.03 0.01 blup 91 0.02 2.4e-03 -6.8 -9.1 8.0e-20 0.76 0.04 0.48 FALSE