Best TWAS P=3.09e-12 · Best GWAS P=4.77e-11 conditioned to 0.0396
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | C20orf194 | 0.19 | 0.12 | enet | 48 | 0.17 | 9.6e-20 | 6.5 | 6.2 | 4.2e-10 | 0.83 | 0.02 | 0.98 | FALSE |
2 | GTEx | Esophagus Muscularis | C20orf194 | 0.19 | 0.10 | enet | 18 | 0.13 | 3.8e-08 | -3.3 | 5.6 | 2.4e-08 | 0.39 | 0.43 | 0.35 | FALSE |
3 | GTEx | Muscle Skeletal | C20orf194 | 0.10 | 0.08 | lasso | 3 | 0.06 | 1.4e-06 | 6.0 | -6.0 | 2.5e-09 | -0.91 | 0.09 | 0.91 | FALSE |
4 | GTEx | Nerve Tibial | C20orf194 | 0.14 | 0.10 | lasso | 6 | 0.08 | 4.6e-06 | 6.6 | 6.5 | 6.0e-11 | 1.00 | 0.01 | 0.99 | FALSE |
5 | GTEx | Whole Blood | C20orf194 | 0.06 | 0.03 | lasso | 2 | 0.01 | 4.5e-02 | 5.9 | -5.2 | 2.1e-07 | -0.88 | 0.12 | 0.85 | FALSE |
6 | ROSMAP | Brain Pre-frontal Cortex | C20orf194 | 0.13 | 0.04 | enet | 14 | 0.11 | 9.8e-14 | -2.3 | 5.6 | 2.1e-08 | 0.52 | 0.50 | 0.50 | FALSE |
7 | The Cancer Genome Atlas | Colon Adenocarcinoma | C20orf194 | 0.06 | 0.00 | blup | 97 | 0.03 | 7.5e-03 | 4.6 | 6.7 | 1.8e-11 | 0.80 | 0.06 | 0.68 | FALSE |
8 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C20orf194 | 0.05 | 0.04 | blup | 98 | 0.03 | 6.3e-04 | 6.5 | 7.0 | 3.1e-12 | 0.75 | 0.02 | 0.95 | TRUE |
9 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | C20orf194 | 0.08 | 0.01 | blup | 98 | 0.04 | 2.8e-03 | 4.0 | 5.3 | 8.7e-08 | 0.75 | 0.03 | 0.54 | FALSE |
10 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | ITPA | 0.31 | 0.08 | blup | 54 | 0.11 | 8.1e-04 | 3.2 | -5.3 | 1.3e-07 | -0.52 | 0.02 | 0.20 | FALSE |