[Hub]/) : Traits : Sitting height : ← →

chr19:56,303,291-57,829,846

Best TWAS P=3.03e-10 · Best GWAS P=6.27e-08 conditioned to 0.0983

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	ZNF71	0.12	0.06	lasso	3	0.05	9.0e-05	-5.3	5.3	1.4e-07	-0.79	0.01	0.98	FALSE
2	GTEx	Adipose Subcutaneous	AC007228.11	0.10	0.04	lasso	5	0.06	2.2e-05	4.9	5.3	1.1e-07	-0.54	0.05	0.94	FALSE
3	GTEx	Adipose Visceral Omentum	AC007228.11	0.14	0.04	lasso	6	0.06	6.9e-04	5.1	5.4	6.3e-08	-0.50	0.03	0.95	FALSE
4	GTEx	Artery Aorta	AC007228.11	0.31	0.22	enet	24	0.23	6.5e-13	5.1	5.6	2.3e-08	-0.54	0.03	0.97	FALSE
5	GTEx	Artery Coronary	AC007228.11	0.30	0.15	lasso	6	0.10	2.1e-04	4.5	5.2	2.0e-07	-0.49	0.04	0.92	FALSE
6	GTEx	Brain Caudate basal ganglia	ZNF471	0.22	0.22	enet	5	0.15	3.9e-05	5.3	-5.2	2.3e-07	0.55	0.03	0.96	FALSE
7	GTEx	Brain Cerebellar Hemisphere	ZNF471	0.51	0.13	enet	19	0.02	1.1e-01	5.3	-5.3	9.8e-08	0.74	0.03	0.92	FALSE
8	GTEx	Brain Cerebellum	ZNF471	0.24	0.25	enet	14	0.20	1.2e-06	4.8	-5.5	2.9e-08	0.72	0.04	0.94	FALSE
9	GTEx	Brain Cerebellum	AC007228.11	0.62	0.40	lasso	11	0.54	9.5e-19	5.3	5.4	5.1e-08	-0.52	0.02	0.98	FALSE
10	GTEx	Brain Hypothalamus	AC007228.11	0.39	0.24	lasso	6	0.22	8.8e-06	5.1	5.6	2.7e-08	-0.46	0.03	0.93	FALSE
11	GTEx	Brain Nucleus accumbens basal ganglia	AC007228.11	0.46	0.26	lasso	5	0.11	6.1e-04	-4.7	5.4	5.4e-08	-0.54	0.05	0.94	FALSE
12	GTEx	Breast Mammary Tissue	ZNF471	0.33	0.15	lasso	3	0.13	4.2e-07	5.3	-5.2	1.8e-07	0.55	0.02	0.98	FALSE
13	GTEx	Breast Mammary Tissue	ZNF71	0.14	0.13	lasso	3	0.11	1.9e-06	-5.4	5.3	9.2e-08	-0.75	0.01	0.99	FALSE
14	GTEx	Cells Transformed fibroblasts	ZFP28	0.21	0.13	lasso	9	0.13	4.5e-10	-5.3	5.5	3.2e-08	-0.79	0.01	0.99	FALSE
15	GTEx	Colon Sigmoid	ZNF471	0.30	0.10	lasso	4	0.07	1.5e-03	4.8	-5.3	9.8e-08	0.54	0.04	0.88	FALSE
16	GTEx	Colon Sigmoid	AC007228.11	0.21	0.19	lasso	3	0.15	7.9e-06	5.1	5.1	3.0e-07	-0.40	0.04	0.95	FALSE
17	GTEx	Esophagus Mucosa	ZNF470	0.18	0.05	enet	14	0.05	2.8e-04	-5.4	5.6	1.8e-08	-0.92	0.01	0.98	FALSE
18	GTEx	Heart Left Ventricle	ZNF471	0.19	0.08	enet	15	0.05	1.6e-03	4.8	-5.3	1.4e-07	0.55	0.06	0.93	FALSE
19	GTEx	Lung	ZNF71	0.11	0.09	lasso	1	0.08	1.9e-06	-5.3	5.3	9.3e-08	-0.79	0.01	0.99	FALSE
20	GTEx	Muscle Skeletal	ZNF667-AS1	0.07	0.07	lasso	4	0.08	6.2e-08	-5.3	5.1	2.8e-07	-0.79	0.01	0.99	FALSE
21	GTEx	Muscle Skeletal	ZNF71	0.07	0.08	lasso	2	0.07	1.8e-07	-5.3	5.3	1.0e-07	-0.79	0.01	0.99	FALSE
22	GTEx	Muscle Skeletal	AC007228.11	0.11	0.05	enet	14	0.06	1.6e-06	4.4	5.4	6.4e-08	-0.50	0.08	0.91	FALSE
23	GTEx	Ovary	AC007228.11	0.29	0.04	lasso	7	0.12	6.6e-04	5.1	5.6	2.4e-08	-0.54	0.04	0.68	FALSE
24	GTEx	Skin Sun Exposed Lower leg	ZNF471	0.15	0.09	lasso	4	0.08	2.8e-07	5.3	-5.3	1.1e-07	0.52	0.01	0.99	FALSE
25	GTEx	Skin Sun Exposed Lower leg	ZFP28	0.19	0.13	lasso	9	0.17	1.1e-13	5.1	5.7	1.2e-08	-0.56	0.06	0.94	FALSE
26	GTEx	Spleen	AC007228.11	0.25	0.08	enet	23	0.07	6.0e-03	-5.4	6.3	3.0e-10	-0.66	0.02	0.88	TRUE
27	GTEx	Whole Blood	ZFP28	0.11	0.10	enet	12	0.09	2.5e-08	4.2	5.3	9.2e-08	-0.57	0.36	0.61	FALSE
28	GTEx	Whole Blood	AC007228.11	0.11	0.01	lasso	5	0.00	2.1e-01	5.1	5.2	2.1e-07	-0.41	0.05	0.76	FALSE
29	METSIM	Adipose	ZFP28	0.13	0.09	bslmm	490	0.12	7.3e-17	4.5	5.9	3.9e-09	-0.58	0.09	0.91	FALSE
30	METSIM	Adipose	ZNF71	0.06	0.07	lasso	2	0.07	1.4e-10	-5.3	5.3	1.1e-07	-0.78	0.01	0.99	FALSE
31	NTR	Blood	ZFP28	0.06	0.05	lasso	7	0.06	1.3e-18	-5.3	5.9	3.7e-09	-0.79	0.01	0.99	FALSE
32	YFS	Blood	ZNF470	0.04	0.02	bslmm	476	0.02	3.4e-07	-5.3	5.3	1.4e-07	-0.70	0.01	0.99	FALSE
33	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZFP28	0.02	0.01	enet	4	0.02	1.2e-04	-5.3	5.2	1.8e-07	-0.72	0.01	0.98	FALSE
34	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZNF470	0.05	0.05	lasso	3	0.05	4.0e-10	-5.3	5.6	2.6e-08	-0.77	0.01	0.99	FALSE
35	The Cancer Genome Atlas	Colon Adenocarcinoma	ZNF470	0.05	0.02	blup	73	0.04	3.1e-03	-4.9	6.3	3.2e-10	-0.78	0.01	0.78	FALSE
36	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ZNF470	0.06	0.02	blup	72	0.03	1.8e-04	-5.3	5.6	2.3e-08	-0.76	0.01	0.99	FALSE
37	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZFP28	0.03	0.02	enet	5	0.02	1.1e-03	-4.7	5.5	3.9e-08	-0.65	0.03	0.66	FALSE
38	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZNF470	0.14	0.17	lasso	2	0.16	7.3e-18	-5.3	5.3	1.0e-07	-0.78	0.01	0.99	FALSE
39	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZFP28	0.05	0.02	blup	70	0.03	1.5e-04	-4.9	5.2	1.7e-07	-0.82	0.01	0.93	FALSE
40	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF470	0.08	0.08	blup	73	0.10	2.1e-11	-5.4	5.2	2.5e-07	-0.84	0.01	0.99	FALSE
41	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ZNF470	0.10	0.07	lasso	3	0.08	3.3e-04	-5.3	5.6	2.6e-08	-0.80	0.01	0.94	FALSE
42	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZNF471	0.19	0.22	blup	76	0.25	7.4e-26	5.3	-5.3	1.0e-07	0.43	0.01	0.99	FALSE
43	The Cancer Genome Atlas	Stomach Adenocarcinoma	ZNF71	0.07	0.05	blup	78	0.02	1.6e-02	-4.9	5.8	5.2e-09	-0.73	0.00	0.98	FALSE
44	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF470	0.04	0.00	blup	73	0.02	1.1e-02	-4.7	5.2	2.5e-07	-0.59	0.01	0.32	FALSE
45	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF471	0.14	0.17	lasso	6	0.17	2.9e-16	5.3	-5.2	2.4e-07	0.56	0.02	0.98	FALSE