Best TWAS P=4.77e-10 · Best GWAS P=4.71e-12 conditioned to 2.11e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TRMU | 0.08 | 0.00 | bslmm | 471 | 0.02 | 2.7e-03 | 4.3 | 5.2 | 2.3e-07 | 0.56 | 0.07 | 0.09 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | FBLN1 | 0.09 | 0.04 | lasso | 9 | 0.06 | 2.4e-05 | 5.2 | -6.2 | 4.8e-10 | -0.02 | 0.10 | 0.63 | TRUE |
| 3 | The Cancer Genome Atlas | Esophageal Carcinoma | SMC1B | 0.10 | 0.01 | blup | 86 | 0.02 | 8.5e-02 | -5.2 | -5.1 | 2.7e-07 | -0.05 | 0.04 | 0.44 | FALSE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | RIBC2 | 0.11 | 0.02 | blup | 58 | 0.09 | 2.0e-04 | -4.9 | -5.6 | 1.9e-08 | -0.05 | 0.02 | 0.84 | FALSE |