Best TWAS P=1.21e-07 · Best GWAS P=3.74e-11 conditioned to 5.78e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | PUS10 | 0.04 | 0.01 | lasso | 3 | 0.03 | 4.9e-05 | -3.1 | -5.3 | 1.2e-07 | 0.73 | 0.01 | 0.96 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | AC016747.3 | 0.08 | 0.04 | bslmm | 310 | 0.04 | 2.9e-06 | 4.6 | 5.2 | 2.3e-07 | -0.56 | 0.70 | 0.18 | FALSE |