Best TWAS P=1.03e-31 · Best GWAS P=3.18e-43 conditioned to 3.1e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | EFEMP1 | 0.19 | 0.10 | lasso | 8 | 0.08 | 3.7e-03 | -11.73 | -11.7 | 1.0e-31 | 0.78 | 0.04 | 0.70 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | EFEMP1 | 0.11 | 0.00 | enet | 22 | 0.05 | 1.1e-04 | 0.24 | -6.8 | 1.4e-11 | 0.39 | 0.16 | 0.57 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EFEMP1 | 0.02 | 0.01 | blup | 79 | 0.02 | 3.9e-05 | -13.78 | 6.6 | 3.8e-11 | -0.73 | 0.00 | 1.00 | FALSE |