Best TWAS P=8.27e-09 · Best GWAS P=3.09e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | CPE | 0.12 | 0.09 | lasso | 2 | 0.06 | 9.3e-05 | 5.9 | 5.8 | 8.3e-09 | 0.97 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Nerve Tibial | CPE | 0.21 | 0.21 | lasso | 8 | 0.19 | 1.6e-13 | 5.4 | 5.4 | 7.3e-08 | 0.90 | 0.06 | 0.94 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | CPE | 0.09 | 0.06 | lasso | 8 | 0.04 | 1.4e-04 | 5.4 | 5.4 | 5.3e-08 | 0.92 | 0.02 | 0.98 | FALSE |
| 4 | GTEx | Testis | CPE | 0.39 | 0.38 | lasso | 10 | 0.34 | 4.7e-16 | 5.4 | -5.6 | 2.3e-08 | -0.93 | 0.03 | 0.97 | FALSE |