Best TWAS P=1.95e-07 · Best GWAS P=6.52e-08 conditioned to 0.0662
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Coronary | TMEM110 | 0.17 | 0.05 | lasso | 8 | 0.07 | 3.1e-03 | -4.1 | 5.2 | 2.0e-07 | -0.86 | 0.03 | 0.88 | TRUE |
2 | METSIM | Adipose | ITIH4 | 0.35 | 0.24 | bslmm | 389 | 0.27 | 4.2e-41 | 4.0 | 5.2 | 2.6e-07 | -0.51 | 0.67 | 0.28 | FALSE |