Best TWAS P=4.74e-08 · Best GWAS P=3.79e-07 conditioned to 0.205
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | CSE1L | 0.12 | 0.03 | lasso | 6 | 0.04 | 3.8e-04 | -4.7 | -5.4 | 5.7e-08 | -0.69 | 0.04 | 0.94 | FALSE |
| 2 | GTEx | Colon Transverse | ARFGEF2 | 0.11 | 0.07 | enet | 12 | 0.09 | 2.9e-05 | -4.5 | -5.5 | 4.7e-08 | -0.79 | 0.04 | 0.92 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CSE1L | 0.05 | 0.07 | blup | 50 | 0.07 | 3.2e-08 | 4.9 | -5.3 | 1.5e-07 | -0.78 | 0.02 | 0.98 | FALSE |