312 significantly associated models · 76 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 96492298 | 97978299 | 1 | 1 | 2.2e-07 | 3.3e-06 | 1.5e-02 | 72 | PTBP2 |
2 | 1 | 204982713 | 206329620 | 5 | 1 | 3.2e-11 | 6.7e-10 | 3.4e-01 | 98 | PM20D1 |
3 | 2 | 23729232 | 25278723 | 2 | 1 | 5.7e-08 | 2.6e-08 | 1.0e+00 | 100 | AC009228.1 |
4 | 2 | 200473658 | 202044716 | 1 | 1 | 7.3e-09 | 9.4e-10 | 1.4e-02 | 84 | SPATS2L |
5 | 3 | 46365783 | 48077701 | 2 | 1 | 2.2e-07 | 8.1e-08 | 2.6e-02 | 83 | SETD2 |
6 | 5 | 111499732 | 112950045 | 6 | 1 | 1.2e-10 | 2.0e-10 | 8.9e-02 | 93 | REEP5 |
7 | 5 | 138933151 | 140423473 | 2 | 1 | 4.4e-11 | 2.0e-11 | 1.1e-01 | 94 | PFDN1 |
8 | 6 | 97341715 | 97979053 | 1 | 1 | 1.0e-07 | 9.8e-06 | 2.4e-03 | 53 | C6orf167 |
9 | 6 | 108183628 | 109704062 | 1 | 1 | 4.2e-09 | 4.4e-11 | 2.6e-03 | 79 | FOXO3 |
10 | 7 | 44090853 | 45498400 | 1 | 1 | 1.1e-07 | 1.4e-08 | 1.2e-02 | 80 | ZMIZ2 |
11 | 7 | 122978928 | 124733550 | 1 | 1 | 3.8e-08 | 3.7e-09 | 2.4e-04 | 61 | RP5-921G16.1 |
12 | 9 | 85899677 | 87315117 | 2 | 1 | 8.8e-12 | 6.7e-11 | 4.8e-01 | 99 | RMI1 |
13 | 10 | 12239118 | 13839729 | 1 | 1 | 4.0e-08 | 1.1e-04 | 1.2e-01 | 84 | CCDC3 |
14 | 10 | 14555086 | 16102103 | 1 | 1 | 1.3e-07 | 2.1e-07 | 1.0e-01 | 90 | FAM171A1 |
15 | 11 | 30764890 | 32226445 | 1 | 1 | 1.4e-07 | 4.3e-06 | 7.7e-06 | 5 | IMMP1L |
16 | 11 | 45258966 | 48285906 | 14 | 1 | 4.6e-13 | 2.7e-11 | 3.2e-02 | 90 | ARHGAP1 |
17 | 11 | 63295034 | 64687797 | 1 | 1 | 1.8e-07 | 5.4e-07 | 1.0e+00 | 100 | TRPT1 |
18 | 12 | 48605088 | 50199949 | 6 | 1 | 5.2e-12 | 4.2e-13 | 4.3e-03 | 84 | CCDC65 |
19 | 12 | 111154626 | 113517494 | 12 | 1 | 3.2e-12 | 2.1e-11 | 6.5e-02 | 92 | SH2B3 |
20 | 17 | 6907070 | 7410212 | 1 | 1 | 2.7e-07 | 1.6e-07 | 9.9e-08 | -3 | C17orf81 |
21 | 17 | 43871147 | 45510971 | 8 | 2 | 3.0e-24 | 1.2e-19 | 8.5e-01 | 100 | ARL17A KANSL1 |
22 | 17 | 75309351 | 76804316 | 2 | 1 | 1.3e-08 | 1.5e-07 | 8.4e-01 | 100 | AC021593.1 |
23 | 18 | 33665455 | 35103667 | 1 | 1 | 7.6e-08 | 3.9e-10 | 7.0e-04 | 71 | TPGS2 |
24 | 19 | 3309021 | 4735663 | 1 | 1 | 8.0e-08 | 1.8e-10 | 1.6e-04 | 65 | PIAS4 |
25 | 20 | 46840115 | 48410403 | 2 | 1 | 4.7e-08 | 3.8e-07 | 2.0e-01 | 94 | ARFGEF2 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Pituitary | 6 | 0.538 | 2.3 |
GTEx | Liver | 5 | 0.697 | 2.2 |
GTEx | Adrenal Gland | 4 | 0.275 | 2.1 |
GTEx | Brain Frontal Cortex BA9 | 3 | 0.325 | 2.1 |
GTEx | Brain Nucleus accumbens basal ganglia | 4 | 0.462 | 2.1 |
GTEx | Brain Putamen basal ganglia | 1 | 0.160 | 2.1 |
GTEx | Colon Sigmoid | 2 | 0.137 | 2.1 |
GTEx | Esophagus Gastroesophageal Junction | 5 | 0.346 | 2.1 |
GTEx | Esophagus Muscularis | 9 | 0.278 | 2.1 |
GTEx | Heart Left Ventricle | 3 | 0.196 | 2.1 |
GTEx | Muscle Skeletal | 8 | 0.277 | 2.1 |
GTEx | Skin Sun Exposed Lower leg | 12 | 0.330 | 2.1 |
GTEx | Testis | 11 | 0.349 | 2.1 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 1 | 0.197 | 2.1 |
GTEx | Adipose Visceral Omentum | 4 | 0.196 | 2.0 |
GTEx | Artery Aorta | 8 | 0.269 | 2.0 |
GTEx | Artery Coronary | 2 | 0.169 | 2.0 |
GTEx | Artery Tibial | 9 | 0.239 | 2.0 |
GTEx | Brain Cerebellar Hemisphere | 3 | 0.201 | 2.0 |
GTEx | Brain Cerebellum | 4 | 0.202 | 2.0 |
GTEx | Brain Cortex | 3 | 0.290 | 2.0 |
GTEx | Brain Hippocampus | 1 | 0.191 | 2.0 |
GTEx | Breast Mammary Tissue | 6 | 0.304 | 2.0 |
GTEx | Colon Transverse | 6 | 0.291 | 2.0 |
GTEx | Esophagus Mucosa | 9 | 0.271 | 2.0 |
GTEx | Heart Atrial Appendage | 3 | 0.190 | 2.0 |
GTEx | Lung | 7 | 0.244 | 2.0 |
GTEx | Nerve Tibial | 13 | 0.301 | 2.0 |
GTEx | Ovary | 4 | 0.441 | 2.0 |
GTEx | Pancreas | 5 | 0.306 | 2.0 |
GTEx | Skin Not Sun Exposed Suprapubic | 9 | 0.366 | 2.0 |
GTEx | Spleen | 3 | 0.213 | 2.0 |
GTEx | Thyroid | 10 | 0.250 | 2.0 |
GTEx | Whole Blood | 1 | 0.050 | 2.0 |
ROSMAP | Brain Pre-frontal Cortex | 5 | 0.114 | 2.0 |
GTEx | Adipose Subcutaneous | 9 | 0.258 | 1.9 |
GTEx | Brain Caudate basal ganglia | 1 | 0.109 | 1.9 |
GTEx | Brain Hypothalamus | 1 | 0.169 | 1.9 |
GTEx | Breast Mammary Tissue (Male) | 2 | 0.168 | 1.9 |
GTEx | Breast Mammary Tissue (Female) | 2 | 0.122 | 1.9 |
GTEx | Cells EBV-transformed lymphocytes | 4 | 0.281 | 1.9 |
GTEx | Cells Transformed fibroblasts | 5 | 0.119 | 1.9 |
GTEx | Prostate | 4 | 0.479 | 1.9 |
GTEx | Small Intestine Terminal Ileum | 0 | 0.000 | 1.9 |
GTEx | Stomach | 4 | 0.275 | 1.9 |
GTEx | Vagina | 0 | 0.000 | 1.9 |
METSIM | Adipose | 7 | 0.152 | 1.9 |
CommonMind | Brain Pre-frontal Cortex | 10 | 0.186 | 1.9 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 3 | 0.110 | 1.9 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 0 | 0.000 | 1.9 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 3 | 0.281 | 1.9 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 4 | 0.313 | 1.9 |
YFS | Blood | 8 | 0.173 | 1.8 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 2 | 0.121 | 1.8 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 4 | 0.091 | 1.8 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 3 | 0.145 | 1.8 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 0 | 0.000 | 1.8 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 7 | 0.171 | 1.8 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 2 | 0.098 | 1.8 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 5 | 0.116 | 1.8 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 3 | 0.102 | 1.8 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 3 | 0.188 | 1.8 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 2 | 0.120 | 1.8 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 2 | 0.151 | 1.8 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 5 | 0.108 | 1.8 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 0 | 0.000 | 1.8 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 1 | 0.187 | 1.8 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 5 | 0.297 | 1.8 |
The Cancer Genome Atlas | Thyroid Carcinoma | 6 | 0.116 | 1.8 |
GTEx | Uterus | 1 | 0.176 | 1.7 |
NTR | Blood | 1 | 0.042 | 1.7 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 2 | 0.182 | 1.7 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 2 | 0.080 | 1.7 |
The Cancer Genome Atlas | Esophageal Carcinoma | 0 | 0.000 | 1.6 |