Best TWAS P=6.4e-08 · Best GWAS P=5.6e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | DTD1 | 0.09 | 0.04 | lasso | 2 | 0.03 | 3.8e-03 | -5.2 | 5.2 | 1.6e-07 | -0.97 | 0.02 | 0.97 | FALSE |
| 2 | GTEx | Ovary | DTD1 | 0.27 | 0.20 | lasso | 2 | 0.18 | 3.3e-05 | -5.4 | 5.4 | 6.4e-08 | -0.99 | 0.02 | 0.93 | TRUE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | DTD1 | 0.14 | 0.14 | lasso | 4 | 0.13 | 8.9e-08 | -5.3 | 5.3 | 1.0e-07 | -0.96 | 0.01 | 0.99 | FALSE |