[Hub]/) : Traits : Illnesses of father: Heart disease :

chr1:222,096,959-223,537,385

Best TWAS P=6.43e-09 · Best GWAS P=5.54e-09 conditioned to 0.0926

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial RP11-378J18.8 0.06 0.03 enet 14 0.04 0.00041 -4.5 -5.7 1.5e-08 0.85 0.02 0.93 FALSE
2 GTEx Brain Hypothalamus RP11-378J18.8 0.28 0.17 lasso 6 0.07 0.00885 -5.7 -5.5 3.2e-08 0.98 0.01 0.89 FALSE
3 GTEx Cells Transformed fibroblasts RP11-378J18.8 0.09 0.02 enet 9 0.02 0.00565 -4.5 -5.3 1.1e-07 0.89 0.03 0.90 FALSE
4 GTEx Colon Sigmoid RP11-378J18.8 0.29 0.09 lasso 5 0.10 0.00027 -5.7 -5.7 9.9e-09 0.88 0.02 0.96 FALSE
5 GTEx Esophagus Gastroesophageal Junction RP11-378J18.8 0.19 0.05 lasso 9 0.05 0.00643 -5.7 -5.6 1.8e-08 0.95 0.01 0.98 FALSE
6 GTEx Nerve Tibial MIA3 0.08 0.00 lasso 4 0.01 0.06630 -4.5 -5.4 5.4e-08 0.93 0.02 0.94 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma AIDA 0.02 0.01 blup 53 0.02 0.00499 -5.7 5.8 6.4e-09 -0.85 0.01 0.74 TRUE