Best TWAS P=6.43e-09 · Best GWAS P=5.54e-09 conditioned to 0.0926
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RP11-378J18.8 | 0.06 | 0.03 | enet | 14 | 0.04 | 0.00041 | -4.5 | -5.7 | 1.5e-08 | 0.85 | 0.02 | 0.93 | FALSE |
| 2 | GTEx | Brain Hypothalamus | RP11-378J18.8 | 0.28 | 0.17 | lasso | 6 | 0.07 | 0.00885 | -5.7 | -5.5 | 3.2e-08 | 0.98 | 0.01 | 0.89 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | RP11-378J18.8 | 0.09 | 0.02 | enet | 9 | 0.02 | 0.00565 | -4.5 | -5.3 | 1.1e-07 | 0.89 | 0.03 | 0.90 | FALSE |
| 4 | GTEx | Colon Sigmoid | RP11-378J18.8 | 0.29 | 0.09 | lasso | 5 | 0.10 | 0.00027 | -5.7 | -5.7 | 9.9e-09 | 0.88 | 0.02 | 0.96 | FALSE |
| 5 | GTEx | Esophagus Gastroesophageal Junction | RP11-378J18.8 | 0.19 | 0.05 | lasso | 9 | 0.05 | 0.00643 | -5.7 | -5.6 | 1.8e-08 | 0.95 | 0.01 | 0.98 | FALSE |
| 6 | GTEx | Nerve Tibial | MIA3 | 0.08 | 0.00 | lasso | 4 | 0.01 | 0.06630 | -4.5 | -5.4 | 5.4e-08 | 0.93 | 0.02 | 0.94 | FALSE |
| 7 | The Cancer Genome Atlas | Brain Lower Grade Glioma | AIDA | 0.02 | 0.01 | blup | 53 | 0.02 | 0.00499 | -5.7 | 5.8 | 6.4e-09 | -0.85 | 0.01 | 0.74 | TRUE |