Best TWAS P=2.77e-08 · Best GWAS P=1.66e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | NUDCD3 | 0.16 | 0.14 | enet | 31 | 0.13 | 2.7e-05 | 5.2 | 5.4 | 6.5e-08 | 0.96 | 0.03 | 0.96 | FALSE |
| 2 | GTEx | Muscle Skeletal | NUDCD3 | 0.06 | 0.06 | enet | 6 | 0.05 | 6.5e-06 | 5.2 | 5.2 | 1.7e-07 | 1.00 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Whole Blood | NUDCD3 | 0.07 | 0.03 | lasso | 7 | 0.01 | 3.2e-02 | 5.2 | 5.6 | 2.8e-08 | 0.97 | 0.03 | 0.95 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NUDCD3 | 0.03 | 0.03 | lasso | 3 | 0.04 | 1.1e-04 | 5.2 | 5.2 | 1.8e-07 | 1.00 | 0.02 | 0.97 | FALSE |