Best TWAS P=1.33e-11 · Best GWAS P=1.79e-11 conditioned to 0.18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | BTAF1 | 0.20 | 0.09 | enet | 39 | 0.18 | 2.9e-13 | -5.2 | -5.4 | 8.1e-08 | 0.34 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Esophagus Muscularis | EIF2S2P3 | 0.09 | 0.04 | lasso | 6 | 0.04 | 1.1e-03 | -6.3 | -6.8 | 1.3e-11 | 0.91 | 0.02 | 0.93 | TRUE |
| 3 | GTEx | Thyroid | EIF2S2P3 | 0.15 | 0.14 | lasso | 2 | 0.14 | 6.2e-11 | -6.3 | -6.0 | 1.5e-09 | 0.96 | 0.02 | 0.98 | FALSE |