Best TWAS P=1.19e-07 · Best GWAS P=3.1e-07 conditioned to 0.00456
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ASXL3 | 0.04 | 0.01 | blup | 83 | 0.02 | 0.0076 | -5.1 | -5.1 | 2.7e-07 | 0.82 | 0.02 | 0.84 | FALSE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | ASXL3 | 0.12 | 0.04 | lasso | 3 | 0.02 | 0.0384 | -4.8 | -5.3 | 1.2e-07 | 0.50 | 0.06 | 0.70 | TRUE |