Best TWAS P=2.08e-09 · Best GWAS P=2.62e-10 conditioned to 0.000102
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TCF4 | 0.06 | 0.00 | enet | 4 | 0.00 | 5.1e-01 | 5.2 | -6.0 | 2.1e-09 | -0.49 | 0.11 | 0.55 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | TCF4 | 0.04 | 0.06 | lasso | 2 | 0.06 | 1.9e-07 | 5.3 | -5.1 | 2.7e-07 | -0.26 | 0.72 | 0.27 | FALSE |