TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced expiratory volume in 1-second (FEV1), Best measure
:
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chr6:125,970,401-127,355,237
Best TWAS P=5.25e-16 · Best GWAS P=2.89e-19 conditioned to 0.000119
126M
126.2M
126.4M
126.6M
126.8M
127M
127.2M
127.4M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
CENPW
0.04
0.06
lasso
10
0.06
2.4e-07
7.9
-8.1
5.2e-16
0.89
0.38
0.62
TRUE
4
The Cancer Genome Atlas
Brain Lower Grade Glioma
CENPW
0.04
0.06
blup
35
0.05
9.2e-07
7.9
-8.0
1.5e-15
0.87
0.02
0.98
FALSE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
CENPW
0.04
0.05
lasso
5
0.05
2.6e-06
7.9
-7.8
4.2e-15
0.87
0.02
0.98
FALSE
2
METSIM
Adipose
CENPW
0.02
0.02
blup
189
0.01
8.3e-03
7.9
-7.1
1.3e-12
0.69
0.07
0.24
FALSE