Best TWAS P=5.25e-16 · Best GWAS P=2.89e-19 conditioned to 0.000119
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CENPW | 0.04 | 0.06 | lasso | 10 | 0.06 | 2.4e-07 | 7.9 | -8.1 | 5.2e-16 | 0.89 | 0.38 | 0.62 | TRUE |
| 2 | METSIM | Adipose | CENPW | 0.02 | 0.02 | blup | 189 | 0.01 | 8.3e-03 | 7.9 | -7.1 | 1.3e-12 | 0.69 | 0.07 | 0.24 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CENPW | 0.04 | 0.05 | lasso | 5 | 0.05 | 2.6e-06 | 7.9 | -7.8 | 4.2e-15 | 0.87 | 0.02 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CENPW | 0.04 | 0.06 | blup | 35 | 0.05 | 9.2e-07 | 7.9 | -8.0 | 1.5e-15 | 0.87 | 0.02 | 0.98 | FALSE |