Hub : Traits :

Forced expiratory volume in 1-second (FEV1), Best measure

1980 significantly associated models · 411 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 9049032 9576675 1 1 1.6e-07 4.2e-06 2.8e-04 38 H6PD
2 1 16273995 17989765 6 1 1.0e-09 2.1e-09 3.2e-01 97 MST1P2
3 1 22197336 22718991 1 1 3.4e-10 2.4e-11 2.0e-05 59 WNT4
4 1 25475418 27595862 8 2 4.0e-12 3.5e-12 2.6e-01 97 DHDDS TRIM63
5 1 37307281 38731622 4 2 1.6e-08 4.9e-08 1.0e+00 100 DNALI1 FHL3
6 1 40748755 42406344 2 1 5.0e-19 6.5e-15 7.2e-01 100 SCMH1
7 1 50735395 52135979 1 1 2.8e-07 3.7e-08 3.2e-02 85 CDKN2C
8 1 67814420 69212053 1 1 2.8e-08 4.8e-07 2.6e-01 95 DIRAS3
9 1 77655651 79300939 3 1 5.8e-09 1.1e-08 1.0e-01 92 GIPC2
10 1 111034818 112443281 1 1 1.4e-07 5.6e-08 1.0e+00 100 DENND2D
11 1 149672809 151659071 8 2 1.4e-09 1.6e-10 5.6e-03 81 CTSS PPIAL4C
12 1 178129899 179534540 1 1 7.4e-09 1.3e-10 4.8e-03 81 ANGPTL1
13 1 180186713 181614143 1 1 2.4e-07 1.5e-07 1.0e+00 100 KIAA1614
14 1 183325796 184739300 1 1 2.1e-07 2.8e-06 4.0e-01 97 TSEN15
15 1 203785948 205241659 1 1 3.7e-09 7.9e-08 1.1e-01 91 MDM4
16 2 23453834 25889403 5 2 1.5e-11 9.1e-13 3.5e-02 91 ADCY3 UBXN2A
17 2 36044351 37567226 3 1 2.6e-08 6.9e-08 4.2e-02 86 RP11-78I14.1
18 2 55401562 56843605 1 2 4.7e-26 1.5e-30 2.2e-02 96 EFEMP1
19 2 69829251 71228388 1 1 1.7e-07 4.1e-05 5.9e-01 98 FAM136A
20 2 100193898 101629737 1 1 8.7e-09 3.2e-10 1.1e-02 83 LONRF2
21 2 135898023 137435625 3 1 5.3e-11 1.5e-08 9.7e-03 79 DARS
22 2 168949234 170419444 1 1 3.3e-08 2.8e-09 1.5e-06 34 NOSTRIN
23 2 177559549 179175022 3 1 5.7e-11 1.1e-08 5.7e-01 99 AC073834.3
24 2 218300530 219878756 2 1 2.9e-10 2.3e-11 5.0e-08 34 PNKD
25 2 231967886 233349588 1 1 2.0e-10 4.2e-10 4.4e-01 98 RP11-690I21.1
26 2 241805851 243048760 1 1 4.8e-17 6.3e-15 6.3e-01 100 BOK
27 3 40537829 41986787 1 1 2.6e-08 1.3e-07 8.5e-01 100 CTNNB1
28 3 48618666 50620043 12 1 3.4e-10 9.1e-08 5.9e-03 74 RNF123
29 3 56629678 58613378 3 2 1.6e-08 1.0e-10 7.3e-03 83 HESX1 SLMAP
30 3 128334272 129714372 1 1 5.2e-09 3.2e-09 4.9e-03 77 H1FX
31 3 140350567 141867638 1 1 1.4e-09 1.1e-09 1.0e+00 100 ZBTB38
32 3 157125828 159106064 3 1 9.3e-12 1.7e-10 3.2e-01 98 RP11-538P18.2
33 4 686563 2058475 1 1 5.9e-08 2.7e-06 1.7e-01 92 CRIPAK
34 4 2825660 4219590 1 1 2.3e-08 9.8e-07 4.8e-03 67 LRPAP1
35 4 17104059 18507692 2 1 3.2e-36 5.7e-31 1.7e-03 93 DCAF16
36 4 57080198 58531645 4 1 3.8e-09 3.1e-09 1.0e+00 100 C4orf14
37 4 105373669 107622327 5 3 5.6e-26 1.7e-29 7.6e-02 98 GSTCD PPA2
38 4 144230902 146788825 4 2 1.1e-30 6.0e-40 6.1e-08 83 HHIP-AS1 OTUD4
39 5 43243774 43940059 2 1 9.5e-08 5.4e-06 9.0e-01 100 C5orf34
40 5 77052232 78753539 2 1 6.1e-10 1.1e-12 4.4e-04 76 AP3B1
41 5 107390303 109224099 1 1 3.0e-08 5.5e-07 1.9e-02 78 FER
42 5 114443019 115851911 1 1 1.5e-07 1.7e-06 8.0e-01 100 CDO1
43 5 121480516 123002130 2 2 7.3e-11 8.4e-13 9.4e-03 87 CEP120 CTB-36H16.2
44 5 130936652 132401730 4 1 3.4e-08 2.7e-07 3.5e-02 83 SLC22A4
45 5 139323257 141214127 11 1 5.7e-10 6.7e-08 4.5e-01 98 PCDHB5
46 5 147012186 148712150 3 2 4.5e-21 2.3e-26 5.6e-04 90 FBXO38 HTR4
47 5 149903130 151338753 1 1 1.1e-07 2.3e-06 4.3e-01 97 GM2A
48 5 156009720 157697754 2 1 1.1e-15 1.8e-13 3.7e-04 77 ADAM19
49 5 176040488 177260129 2 2 7.2e-09 5.5e-09 3.2e-02 86 MXD3 RAB24
50 6 25266147 26689223 2 3 8.5e-12 3.4e-14 2.9e-01 98 TRIM38 U91328.21
51 6 33745071 36804187 14 10 7.8e-27 1.1e-23 NaN NaN C6orf106 C6orf126 MAPK13 RPL10A SCUBE3 ZNF76
52 6 80120201 81763771 2 1 1.7e-09 1.2e-09 1.0e+00 100 RP11-250B2.6
53 6 108994161 110843638 9 1 1.2e-13 8.3e-14 5.7e-08 47 SMPD2
54 6 115880851 117481404 3 1 6.4e-09 5.8e-08 2.4e-02 83 FAM26F
55 6 125970401 127355237 1 1 5.2e-16 2.9e-19 1.2e-04 82 CENPW
56 6 129638583 131163098 2 1 4.6e-17 5.5e-23 8.0e-14 43 RP11-73O6.3
57 6 134905567 136516257 1 1 2.2e-07 1.1e-06 2.1e-01 93 AHI1
58 6 158487143 159178345 1 1 2.3e-08 8.0e-08 4.6e-03 72 TULP4
59 7 6502367 7988091 1 1 9.0e-10 9.9e-09 1.3e-02 81 C1GALT1
60 7 23296533 23818538 1 1 1.5e-08 3.9e-11 3.4e-04 71 TRA2A
61 7 149847287 151252618 1 1 1.3e-07 5.3e-08 7.2e-03 76 AOC1
62 8 8092025 9669775 2 1 2.9e-08 1.3e-07 2.5e-02 82 ERI1
63 8 11527910 12966739 1 1 1.3e-07 5.9e-07 7.6e-02 87 FAM66A
64 8 123101743 124679448 1 1 1.4e-08 2.0e-10 2.7e-03 78 ZHX2
65 8 130517157 131045893 1 1 1.3e-15 2.3e-13 6.8e-01 100 GSDMC
66 8 135106207 136500554 1 1 1.1e-09 2.2e-10 3.3e-02 89 AC083843.1
67 9 97945796 99474182 1 1 1.2e-07 4.6e-07 2.9e-07 -4 ERCC6L2
68 9 100871717 102304304 1 1 3.1e-07 2.5e-05 5.8e-03 57 GALNT12
69 9 135629944 137034272 1 1 4.9e-08 1.0e-11 2.6e-05 62 CACFD1
70 9 138403706 139836362 1 1 2.4e-16 3.7e-14 6.6e-01 100 QSOX2
71 10 11515875 13569805 3 2 1.3e-20 1.8e-24 2.7e-04 87 CDC123 NUDT5
72 10 30435876 32016090 1 1 1.3e-08 6.8e-08 4.9e-02 87 ZNF438
73 10 63870456 65606229 2 1 2.0e-09 2.1e-09 4.5e-02 89 ADO
74 10 74317852 76323150 8 2 5.5e-10 8.8e-10 5.6e-01 99 DNAJC9-AS1 SEC24C
75 10 76664253 79018276 1 1 2.3e-12 2.3e-16 1.2e-05 71 C10orf11
76 10 80443273 81901722 1 1 1.3e-07 1.2e-06 4.8e-06 12 ZCCHC24
77 10 95379543 96818402 1 1 3.4e-08 1.4e-07 6.0e-01 99 NOC3L
78 11 8348340 9847690 1 1 1.1e-08 9.5e-07 9.9e-01 100 SCUBE2
79 11 32812529 33376095 1 1 2.0e-07 9.3e-07 4.2e-01 97 TCP11L1
80 11 46010847 48360648 11 7 1.4e-09 9.2e-10 1.0e+00 100 ACP2 ARHGAP1 C1QTNF4 PSMC3
81 11 61627881 63110149 7 1 2.4e-11 1.0e-10 5.1e-01 99 EEF1G
82 11 65594820 69476279 8 4 1.5e-24 1.0e-22 1.0e+00 100 CCDC87 IGHMBP2 RAD9A SAPS3
83 11 72399607 74006925 4 1 1.5e-10 9.3e-09 1.9e-01 95 FAM168A
84 12 27616589 29042392 1 1 1.7e-10 5.1e-10 2.4e-01 96 RP11-967K21.1
85 12 30084002 31526510 1 1 7.1e-09 2.0e-09 1.0e+00 100 IPO8
86 12 55633142 57684978 13 7 1.1e-11 1.2e-10 NaN NaN CNPY2 COQ10A PAN2 RAB5B RP11-977G19.11
87 12 93165619 94589220 1 1 4.7e-09 4.3e-16 1.1e-09 44 MRPL42
88 12 95167773 96606889 1 1 3.8e-08 5.6e-06 1.7e-01 91 METAP2
89 13 49557805 51390447 4 6 1.2e-14 1.3e-14 1.0e+00 100 DLEU2 EBPL
90 13 110598964 112060514 1 1 2.6e-07 2.1e-07 6.2e-02 87 CARS2
91 14 92286262 93847625 1 1 1.7e-12 8.5e-13 1.0e+00 100 RIN3
92 15 70697945 72771648 1 1 3.5e-09 1.3e-11 1.1e-04 67 THSD4
93 15 73524629 74915888 1 1 4.4e-10 5.7e-17 5.8e-09 52 LOXL1-AS1
94 15 78032707 79537269 5 1 2.0e-12 1.9e-13 2.8e-02 91 PSMA4
95 15 82250003 85883064 18 11 1.5e-16 2.2e-29 NaN NaN AC103965.1 BTBD1 GOLGA6L4 GOLGA6L5 RP11-382A20.2 WHAMM ZSCAN2
96 15 98944630 101209341 3 2 1.0e-09 2.2e-11 7.2e-08 35 CTD-3076O17.1 SYNM
97 16 2741812 5510848 9 2 2.8e-12 1.3e-11 4.3e-03 82 CLUAP1 ZNF500
98 16 30154740 31833122 15 1 6.2e-13 3.4e-11 3.2e-01 98 RP11-196G11.2
99 16 68681792 71093625 10 3 1.6e-13 6.3e-16 3.9e-01 99 NFAT5 NOB1 TMED6
100 16 88030355 89448663 2 1 4.5e-09 2.5e-08 6.0e-03 76 SNAI3-AS1
101 17 923916 2420934 3 1 4.9e-10 3.5e-09 2.8e-01 97 SERPINF1
102 17 29482878 31275580 6 1 1.8e-08 1.9e-08 1.4e-01 93 CTC-542B22.2
103 17 36211659 37597185 1 1 2.1e-09 2.7e-09 1.0e+00 100 PCGF2
104 17 42774693 45876022 23 6 3.5e-31 1.8e-27 1.0e+00 100 ARL17A LRRC37A LRRC37A2 NSFP1 RP11-669E14.6 WNT3
105 17 60821100 63531331 17 7 3.6e-22 1.2e-19 1.0e+00 100 CD79B CYB561 ICAM2 PLEKHM1P PSMC5 SMARCD2
106 17 79202465 80694826 8 1 7.4e-16 1.5e-14 1.0e-01 96 ASPSCR1
107 18 8010444 9532097 1 1 4.6e-09 2.2e-09 3.2e-02 87 SOGA2
108 19 10068513 11873382 4 1 1.1e-09 3.3e-11 2.8e-03 80 LOC147727
109 19 42489516 42990382 1 1 2.7e-08 1.6e-08 4.9e-02 88 GSK3A
110 20 9925555 11347455 1 1 5.3e-10 2.9e-10 8.4e-04 72 JAG1
111 20 24485525 26307797 7 1 2.2e-08 3.2e-08 8.0e-02 90 ABHD12
112 20 30060562 31870640 4 1 3.3e-08 1.6e-08 1.0e+00 100 TSPY26P
113 20 32603830 34288854 5 2 1.1e-10 1.4e-08 7.7e-01 100 GDF5 TP53INP2
114 20 46838455 48591758 5 1 4.5e-12 1.1e-12 1.3e-02 88 ARFGEF2
115 20 61636050 62912463 5 1 6.0e-11 6.0e-10 2.1e-02 86 TPD52L2
116 22 17581838 19203078 1 1 1.3e-11 2.7e-10 1.8e-01 96 MICAL3
117 22 29707908 31171274 2 1 2.4e-11 2.3e-13 6.9e-04 79 CTA-85E5.10

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Bipolar Disorder (2018) 1.54 3 0 0.0 -0.97 2.5e-02 AC103965.1 LOC147727 ZSCAN2
Bipolar Disorder or Schizophrenia 1.89 8 3 6.7 -0.51 1.3e-01 AC103965.1 GOLGA6L4 GOLGA6L5 PCDHB5 PSMA4 TRIM38 U91328.21 ZSCAN2
Depressed Affect (Nagel 2018) 2.04 6 4 8.9 -0.68 1.4e-01 C1QTNF4 LRRC37A LRRC37A2 RP11-196G11.2 RP11-669E14.6 WNT3
Depression (Nagel 2018) 1.53 1 0 0.0 0.00 1.0e+00 WNT3
Intelligence (Savage-Jansen 2018) 1.80 14 9 20.0 0.90 9.1e-07 ACP2 ARL17A C1QTNF4 CENPW CTNNB1 DCAF16 DLEU2 NSFP1 PCDHB5 PPA2 RNF123 TULP4 UBXN2A WNT3
Neuroticism (Nagel 2018) 2.34 11 7 15.6 -0.68 2.1e-02 ARL17A C1QTNF4 CENPW FBXO38 LRRC37A LRRC37A2 NSFP1 RP11-196G11.2 RP11-669E14.6 U91328.21 WNT3
Schizophrenia (2018) 1.69 6 3 6.7 -0.44 2.8e-01 AC103965.1 PCDHB5 PSMA4 TRIM38 U91328.21 ZSCAN2
Worry (Nagel 2018) 1.92 9 5 11.1 -0.84 5.0e-03 ARL17A CENPW FBXO38 LRRC37A LRRC37A2 NSFP1 RP11-196G11.2 RP11-669E14.6 WNT3
Alzheimer’s Disease (including proxy) 1.18 1 0 0.0 0.00 1.0e+00 RP11-196G11.2
Crohns Disease (2017) 1.35 5 4 8.9 0.29 6.4e-01 ADCY3 ADO SLC22A4 TPD52L2 ZBTB38
Irritable Bowel Disease (IBD) 1.27 5 3 6.7 0.00 1.0e+00 ADCY3 ADO CTSS SLC22A4 TPD52L2
Ulcerative Colitis (UC) 1.10 2 0 0.0 0.00 1.0e+00 RNF123 SLC22A4
Reaction Time 1.72 4 2 4.4 -0.94 5.7e-02 ARL17A LOC147727 NSFP1 SCUBE2
Verbal and Numeric Reasoning (VNR) 2.00 8 6 13.3 0.67 2.3e-02 C1QTNF4 CENPW DCAF16 PPA2 RNF123 TULP4 U91328.21 UBXN2A
Breast Cancer 1.57 9 8 17.8 -0.48 1.9e-01 ADCY3 LRRC37A LRRC37A2 RIN3 RP11-669E14.6 RP11-73O6.3 SLC22A4 WNT3 ZBTB38
Ovarian Cancer 1.70 5 4 8.9 0.81 9.8e-02 DNALI1 LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Prostate Cancer 1.58 1 1 2.2 0.00 1.0e+00 MDM4
Age at First Birth 1.04 1 0 0.0 0.00 1.0e+00 ABHD12
Body Mass Index (BMI) (2010) 1.89 4 2 4.4 -0.99 3.7e-05 ACP2 ADCY3 C1QTNF4 PSMC3
Crohns Disease (2012) 1.49 3 2 4.4 0.00 1.0e+00 ADO SLC22A4 TPD52L2
HDL Cholesterol 2.23 5 4 8.9 0.81 1.5e-02 ACP2 ARHGAP1 C1QTNF4 C6orf106 PSMC3
LDL Cholesterol 1.22 2 1 2.2 0.00 1.0e+00 CACFD1 LOC147727
Lupus 1.47 1 0 0.0 0.00 1.0e+00 ZNF76
Neuroticism (2016) 1.88 4 3 6.7 -0.74 2.6e-01 FAM66A LRRC37A2 RP11-669E14.6 WNT3
Primary Biliary Cirrhosis 1.71 3 0 0.0 0.00 1.0e+00 LRRC37A RP11-669E14.6 WNT3
Schizophrenia (2014) 1.48 3 1 2.2 -0.99 1.3e-02 AC103965.1 GOLGA6L5 H1FX
Triglycerides 1.27 2 0 0.0 0.00 1.0e+00 FAM66A RP11-196G11.2
Blood Eosinophil Count 1.95 34 22 48.9 -0.30 6.3e-02 AC103965.1 AHI1 ARL17A C4orf14 C5orf34 CACFD1 CNPY2 CTSS DLEU2 EBPL FAM136A FAM26F GSK3A HTR4 KIAA1614 LRRC37A LRRC37A2 MAPK13 NOB1 NOSTRIN PCGF2 RAB5B RIN3 RP11-669E14.6 RP11-73O6.3 RPL10A SEC24C SLC22A4 SMPD2 TRIM63 TSPY26P WNT3 ZNF76 ZSCAN2
Blood Platelet Count 1.46 41 30 66.7 -0.35 1.8e-02 ABHD12 AC103965.1 ACP2 ADO ARL17A C1QTNF4 C4orf14 C6orf106 CACFD1 CEP120 CNPY2 CTSS DCAF16 DENND2D FAM136A FER GIPC2 GOLGA6L4 HESX1 HTR4 KIAA1614 LOC147727 LRRC37A LRRC37A2 NSFP1 OTUD4 PNKD PPA2 PSMC3 RIN3 RP11-669E14.6 SCMH1 SLC22A4 SLMAP SMARCD2 SMPD2 TPD52L2 TULP4 ZCCHC24 ZHX2 ZSCAN2
Blood Red Count 2.18 27 19 42.2 -0.34 6.7e-02 AC103965.1 AOC1 ASPSCR1 C6orf106 CACFD1 CCDC87 CD79B CENPW COQ10A DARS FAM136A LRRC37A LRRC37A2 MST1P2 NFAT5 NOB1 PAN2 PSMC5 RAD9A RP11-196G11.2 RP11-669E14.6 RP11-73O6.3 RP11-977G19.11 SMPD2 SNAI3-AS1 WNT3 ZBTB38
Blood White Count 2.05 39 28 62.2 -0.60 6.9e-06 ACP2 ADO AHI1 C1QTNF4 C4orf14 C5orf34 C6orf106 CACFD1 CENPW CEP120 CTB-36H16.2 DCAF16 EBPL FBXO38 FER GM2A GSK3A HTR4 KIAA1614 LRRC37A MICAL3 NOB1 NOSTRIN PCDHB5 PNKD PSMC3 RIN3 RP11-669E14.6 RP11-73O6.3 SCMH1 SCUBE3 SLC22A4 SMARCD2 SMPD2 TRA2A TULP4 UBXN2A ZHX2 ZNF76
Heel T-Score 3.22 53 39 86.7 -0.03 8.2e-01 AC103965.1 ACP2 ADCY3 ARHGAP1 ARL17A ASPSCR1 C4orf14 CACFD1 CDKN2C CEP120 CRIPAK CTA-85E5.10 CTB-36H16.2 CTNNB1 CTSS DCAF16 DIRAS3 DLEU2 EBPL EEF1G FHL3 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 JAG1 KIAA1614 LRRC37A LRRC37A2 NSFP1 PLEKHM1P PSMC3 RAB24 RP11-196G11.2 RP11-669E14.6 RP11-73O6.3 RP11-967K21.1 RPL10A SAPS3 SCMH1 SLMAP SMARCD2 SNAI3-AS1 THSD4 TULP4 WHAMM WNT3 WNT4 ZBTB38 ZCCHC24 ZNF438 ZNF76
BMI 2.19 31 19 42.2 -0.38 2.0e-02 ACP2 ADCY3 AP3B1 ARFGEF2 C1QTNF4 C6orf106 CEP120 CTNNB1 DCAF16 GIPC2 GSDMC GSK3A HTR4 IGHMBP2 LOXL1-AS1 MST1P2 NFAT5 NOB1 OTUD4 PSMC3 RAB24 RAB5B RNF123 RP11-196G11.2 RP11-538P18.2 RP11-73O6.3 SAPS3 SMARCD2 TMED6 TSPY26P ZNF500
Height 9.96 124 115 255.6 0.88 2.5e-46 AC083843.1 AC103965.1 ACP2 ADCY3 ADO AHI1 AOC1 AP3B1 ARFGEF2 ARHGAP1 ARL17A ASPSCR1 BOK C10orf11 C1QTNF4 C4orf14 C6orf106 C6orf126 CACFD1 CCDC87 CD79B CDC123 CDKN2C CDO1 CENPW CEP120 CLUAP1 CNPY2 COQ10A CRIPAK CTA-85E5.10 CTC-542B22.2 CTD-3076O17.1 CTNNB1 CTSS CYB561 DCAF16 DHDDS DIRAS3 DLEU2 DNAJC9-AS1 DNALI1 EBPL EFEMP1 ERCC6L2 FAM136A FAM26F FER FHL3 GDF5 GIPC2 GOLGA6L4 GOLGA6L5 GSDMC GSK3A H1FX H6PD HHIP-AS1 ICAM2 IGHMBP2 IPO8 JAG1 KIAA1614 LOC147727 LOXL1-AS1 LRRC37A LRRC37A2 MAPK13 MDM4 MICAL3 MRPL42 MST1P2 MXD3 NFAT5 NOB1 NOC3L NOSTRIN NSFP1 OTUD4 PAN2 PCDHB5 PLEKHM1P PNKD PPA2 PPIAL4C PSMC3 PSMC5 QSOX2 RAB24 RAD9A RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-669E14.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TMED6 TP53INP2 TPD52L2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT3 WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76 ZSCAN2
Waist Hip Ratio (WHR) 2.59 32 21 46.7 -0.45 6.4e-03 AC103965.1 ADCY3 AP3B1 ASPSCR1 C6orf106 CD79B CENPW CLUAP1 DENND2D DLEU2 EBPL EEF1G GDF5 GIPC2 GOLGA6L5 HHIP-AS1 LOC147727 LRRC37A LRRC37A2 NFAT5 NSFP1 OTUD4 PSMC5 RAB24 RAD9A RP11-669E14.6 RP11-73O6.3 SCUBE2 WNT3 WNT4 ZBTB38 ZSCAN2
Systolic Blood Pressure 1.75 31 17 37.8 -0.34 5.7e-02 ADCY3 ADO ARFGEF2 ARHGAP1 ARL17A C1QTNF4 CARS2 CDC123 CEP120 DCAF16 EFEMP1 FBXO38 FER FHL3 GDF5 GIPC2 HTR4 LRRC37A2 MICAL3 NSFP1 NUDT5 PCDHB5 PLEKHM1P PNKD RIN3 RP11-538P18.2 RP11-669E14.6 RPL10A ZHX2 ZNF500 ZNF76
Smoking Status 1.48 3 0 0.0 0.00 1.0e+00 CNPY2 NOB1 WNT3
Allergy or Eczema 1.56 5 4 8.9 -0.62 1.9e-01 AHI1 C6orf106 RAB5B SLC22A4 ZBTB38
Cardiovascular Disease 1.47 12 5 11.1 -0.84 3.4e-04 ACP2 ADO ARHGAP1 C1GALT1 DCAF16 HTR4 MXD3 RP11-196G11.2 RP11-538P18.2 SLC22A4 SMARCD2 TSPY26P
Hypothyroidism (self reported) 1.34 3 2 4.4 0.00 1.0e+00 AHI1 RAB5B RIN3
Respiratory disease 2.31 11 6 13.3 -0.95 7.3e-07 ADAM19 AHI1 C4orf14 CNPY2 HTR4 RAB5B SCUBE3 SEC24C SLC22A4 TPD52L2 ZNF76
Type 2 Diabetes (T2D) (2018) 1.74 5 1 2.2 -0.65 2.4e-01 C1GALT1 CENPW HTR4 NOB1 NUDT5
Lung FEV1/FVC ratio 8.13 63 50 111.1 0.74 2.7e-13 AC103965.1 ADAM19 ADCY3 ADO BTBD1 C10orf11 C1GALT1 C4orf14 C6orf106 CDC123 CDKN2C CENPW CEP120 CNPY2 CTA-85E5.10 CTC-542B22.2 CTNNB1 DENND2D DNAJC9-AS1 DNALI1 EEF1G EFEMP1 FAM168A FBXO38 GDF5 GIPC2 GM2A GOLGA6L4 GOLGA6L5 GSTCD HESX1 HHIP-AS1 HTR4 LONRF2 LRRC37A LRRC37A2 METAP2 MICAL3 MST1P2 NUDT5 OTUD4 PCGF2 PLEKHM1P PPA2 PSMA4 RAB5B RP11-382A20.2 RP11-669E14.6 RPL10A SCUBE2 SCUBE3 SEC24C SLC22A4 SLMAP SMPD2 SOGA2 SYNM THSD4 TSPY26P WHAMM ZBTB38 ZNF76 ZSCAN2
Lung FVC 6.80 102 75 166.7 0.87 6.9e-33 ABHD12 AC073834.3 ACP2 AHI1 ANGPTL1 AOC1 AP3B1 ARFGEF2 ARL17A ASPSCR1 BOK BTBD1 C10orf11 C1GALT1 C4orf14 C5orf34 C6orf106 C6orf126 CACFD1 CCDC87 CD79B CDC123 CENPW CEP120 CLUAP1 CTA-85E5.10 CTB-36H16.2 CTSS DARS DCAF16 DHDDS DIRAS3 EBPL EEF1G EFEMP1 FAM136A FAM26F FBXO38 GALNT12 GDF5 GM2A GSDMC GSK3A GSTCD HTR4 IGHMBP2 IPO8 JAG1 KIAA1614 LONRF2 LRPAP1 LRRC37A LRRC37A2 MAPK13 MDM4 MICAL3 MST1P2 NFAT5 NOB1 NSFP1 NUDT5 PCDHB5 PLEKHM1P PPA2 PPIAL4C PSMA4 PSMC5 QSOX2 RAB5B RAD9A RIN3 RNF123 RP11-196G11.2 RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-669E14.6 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RPL10A SAPS3 SCMH1 SEC24C SLC22A4 SLMAP SMPD2 SNAI3-AS1 SOGA2 TCP11L1 THSD4 TPD52L2 TRIM63 TSPY26P TULP4 UBXN2A WHAMM WNT3 WNT4 ZBTB38 ZNF438 ZNF76
Neuroticism 2.23 10 6 13.3 -0.73 1.6e-02 ARL17A C1QTNF4 CENPW FBXO38 LRRC37A LRRC37A2 NSFP1 RP11-196G11.2 RP11-669E14.6 WNT3
Chronotype (morning person) 1.46 6 0 0.0 -1.00 4.0e-06 ACP2 C1QTNF4 CRIPAK CTSS CYB561 LOC147727
Hair Pigment 0.70 21 16 35.6 0.15 5.0e-01 ACP2 ARHGAP1 ASPSCR1 BTBD1 C1QTNF4 C4orf14 CCDC87 FAM136A GDF5 IGHMBP2 LOC147727 LRRC37A LRRC37A2 RP11-669E14.6 RP11-73O6.3 SAPS3 SNAI3-AS1 TP53INP2 TULP4 ZBTB38 ZNF76
Tanning 0.82 9 8 17.8 0.38 3.1e-01 ADCY3 ADO CTSS GDF5 MAPK13 METAP2 MXD3 SNAI3-AS1 TP53INP2
Hand grip strength (left) 4.13 34 21 46.7 0.97 9.7e-23 ACP2 ADCY3 AOC1 ARFGEF2 C1QTNF4 C6orf106 CCDC87 CD79B CRIPAK CYB561 DARS DCAF16 FER GDF5 H1FX IGHMBP2 JAG1 LOXL1-AS1 LRRC37A LRRC37A2 NOB1 PSMC3 PSMC5 RAD9A RP11-250B2.6 RP11-669E14.6 RP11-73O6.3 SAPS3 SLC22A4 TRA2A WNT3 ZBTB38 ZCCHC24 ZNF76
Number of treatments/medications taken 1.43 1 0 0.0 0.00 1.0e+00 DCAF16
Sensitivity / hurt feelings 2.22 5 4 8.9 -1.00 1.5e-04 ARL17A LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Frequency of depressed mood in last 2 weeks 1.52 1 0 0.0 0.00 1.0e+00 WNT3
Relative age of first facial hair 2.42 6 5 11.1 -0.78 4.0e-02 C6orf106 LRRC37A LRRC37A2 RP11-669E14.6 WNT3 ZBTB38
Systolic blood pressure, automated reading 2.17 21 7 15.6 -0.48 2.9e-02 ADCY3 ADO ARHGAP1 DCAF16 EFEMP1 ERI1 FAM66A FBXO38 FER FHL3 HTR4 LRRC37A2 NSFP1 NUDT5 PPA2 RP11-538P18.2 RP11-669E14.6 RPL10A U91328.21 ZHX2 ZNF76
Medication: Metformin 1.70 2 0 0.0 0.00 1.0e+00 C1QTNF4 NUDT5
Diabetes (mother) 1.52 1 1 2.2 0.00 1.0e+00 NUDT5
Pack years adult smoking proportion 2.51 2 1 2.2 0.00 1.0e+00 CYB561 PSMA4
Impedance of leg (right) 2.90 35 23 51.1 0.12 4.9e-01 AC103965.1 ADCY3 AOC1 AP3B1 C1QTNF4 C5orf34 C6orf106 CD79B CDO1 CEP120 CTD-3076O17.1 CTSS ERI1 FAM66A GDF5 GOLGA6L4 GOLGA6L5 H1FX IGHMBP2 LOXL1-AS1 MST1P2 OTUD4 PSMC5 RAB24 RAB5B RAD9A RIN3 RP11-382A20.2 RP11-669E14.6 RP11-73O6.3 SAPS3 SMPD2 SNAI3-AS1 WNT4 ZSCAN2
Leg fat-free mass (left) 5.38 60 49 108.9 0.89 9.9e-25 AC083843.1 AOC1 AP3B1 BOK C6orf106 CD79B CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERI1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PNKD PPA2 PSMC5 QSOX2 RAB5B RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZNF500 ZNF76
Trunk fat percentage 3.25 36 24 53.3 0.04 8.2e-01 ABHD12 AC103965.1 ACP2 ADCY3 AP3B1 ARFGEF2 ARL17A C1QTNF4 C6orf106 CENPW CTD-3076O17.1 CTNNB1 DARS EEF1G EFEMP1 GOLGA6L4 GOLGA6L5 HTR4 LRRC37A2 MAPK13 NOB1 NSFP1 OTUD4 PSMC3 PSMC5 RAD9A RIN3 RP11-196G11.2 RP11-669E14.6 RP11-78I14.1 SYNM TPD52L2 WNT3 ZBTB38 ZNF500 ZSCAN2
Hand grip strength (right) 4.09 36 20 44.4 0.96 4.6e-21 ADCY3 ANGPTL1 AOC1 ARFGEF2 C1QTNF4 C6orf106 CD79B CRIPAK CYB561 DARS DCAF16 GDF5 H1FX JAG1 LOXL1-AS1 LRRC37A LRRC37A2 NOB1 NOSTRIN PCGF2 PSMC3 PSMC5 RAD9A RP11-250B2.6 RP11-669E14.6 RP11-73O6.3 SCMH1 SLC22A4 SMARCD2 TP53INP2 TRA2A TULP4 WNT3 ZBTB38 ZCCHC24 ZNF76
Current tobacco smoking 1.37 3 0 0.0 0.76 2.4e-01 C1QTNF4 FAM66A TPD52L2
Fed-up feelings 1.75 5 4 8.9 -0.99 1.8e-03 ARHGAP1 LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Relative age voice broke 1.85 5 4 8.9 -0.99 2.0e-03 LRRC37A LRRC37A2 RP11-669E14.6 SCMH1 WNT3
Taking other prescription medications 1.28 2 0 0.0 0.00 1.0e+00 ADAM19 AHI1
Age when periods started (menarche) 1.92 7 4 8.9 -0.01 9.9e-01 ADCY3 C1QTNF4 CENPW NFAT5 NOB1 RP11-669E14.6 SCMH1
Bilateral oophorectomy (both ovaries removed) 1.04 1 1 2.2 0.00 1.0e+00 WNT4
Heel bone mineral density (BMD) T-score, automated (left) 2.58 14 10 22.2 -0.27 2.9e-01 ACP2 ARHGAP1 CRIPAK DLEU2 EBPL ERI1 FAM66A FHL3 HHIP-AS1 IGHMBP2 JAG1 SAPS3 WNT4 ZNF438
High blood pressure 1.84 14 6 13.3 -0.86 4.8e-05 ACP2 ADO ARFGEF2 ARHGAP1 C1GALT1 DCAF16 ERI1 FAM66A HTR4 RP11-196G11.2 RP11-538P18.2 SLC22A4 TSPY26P U91328.21
Hayfever, allergic rhinitis or eczema 1.40 5 4 8.9 -0.67 1.5e-01 AHI1 C6orf106 RAB5B SLC22A4 ZBTB38
Medication: Levothyroxine sodium 1.38 2 1 2.2 0.00 1.0e+00 ERI1 RAB5B
Sitting height 8.54 98 86 191.1 0.90 1.6e-43 ABHD12 AC073834.3 AC083843.1 AC103965.1 ACP2 ADCY3 AOC1 AP3B1 ARFGEF2 ARHGAP1 ARL17A ASPSCR1 BOK C1QTNF4 C6orf106 CACFD1 CD79B CDKN2C CDO1 CENPW CEP120 COQ10A CRIPAK CTC-542B22.2 CTD-3076O17.1 CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 ERCC6L2 FAM136A FAM26F FHL3 GDF5 GOLGA6L4 GOLGA6L5 GSDMC GSK3A H1FX H6PD HHIP-AS1 ICAM2 IGHMBP2 JAG1 KIAA1614 LOC147727 LOXL1-AS1 LRRC37A LRRC37A2 MRPL42 MST1P2 MXD3 NFAT5 NOB1 NOC3L NOSTRIN OTUD4 PAN2 PCDHB5 PNKD PPA2 PSMC3 PSMC5 QSOX2 RAD9A RP11-250B2.6 RP11-538P18.2 RP11-669E14.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SERPINF1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TMED6 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT3 WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76 ZSCAN2
Chronic bronchitis/emphysema (father) 1.85 1 1 2.2 0.00 1.0e+00 PSMA4
Body mass index (BMI) 2.27 25 11 24.4 -0.52 4.0e-03 ACP2 ADCY3 AP3B1 ARFGEF2 C1QTNF4 C6orf106 CCDC87 CEP120 CTC-542B22.2 DARS DCAF16 ERI1 FAM66A HTR4 IGHMBP2 LOXL1-AS1 MST1P2 NFAT5 NOB1 OTUD4 PSMC3 RAB5B RP11-196G11.2 TMED6 TRIM38
Impedance of leg (left) 2.88 36 23 51.1 0.10 5.5e-01 AC103965.1 ADCY3 AOC1 AP3B1 C1QTNF4 C5orf34 CD79B CDO1 CEP120 CTD-3076O17.1 CTSS ERI1 FAM66A GDF5 GOLGA6L4 GOLGA6L5 H1FX IGHMBP2 LOXL1-AS1 LRRC37A2 MST1P2 OTUD4 PPA2 PSMC5 RAB24 RAB5B RAD9A RIN3 RP11-382A20.2 RP11-669E14.6 RP11-73O6.3 SAPS3 SMPD2 WNT3 WNT4 ZSCAN2
Leg predicted mass (left) 5.37 60 49 108.9 0.89 4.3e-25 AC083843.1 AOC1 AP3B1 BOK C6orf106 CD79B CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERI1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PLEKHM1P PNKD PPA2 PSMC5 RAB5B RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZNF500 ZNF76
Trunk fat mass 3.39 38 26 57.8 0.35 2.0e-02 ABHD12 AC103965.1 ACP2 ADCY3 AP3B1 ARL17A BOK C1QTNF4 C6orf106 CEP120 CTD-3076O17.1 CTNNB1 DLEU2 EEF1G EFEMP1 GDF5 GOLGA6L4 GOLGA6L5 H1FX HTR4 LRRC37A2 MAPK13 NOB1 NSFP1 OTUD4 PSMC3 RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 SYNM TP53INP2 TPD52L2 TRIM38 WNT3 ZBTB38 ZNF500 ZSCAN2
Waist circumference 2.27 21 15 33.3 0.07 7.2e-01 ABHD12 ACP2 ADCY3 AP3B1 C1QTNF4 C6orf106 CEP120 CTNNB1 GOLGA6L4 HTR4 NOB1 OTUD4 PSMC3 RAD9A RP11-196G11.2 RP11-78I14.1 RPL10A TPD52L2 ZBTB38 ZNF500 ZSCAN2
Number of incorrect matches in round 1.53 1 0 0.0 0.00 1.0e+00 RP11-196G11.2
Past tobacco smoking 1.55 4 0 0.0 -0.50 5.0e-01 C4orf14 CNPY2 NOB1 RP11-977G19.11
Nervous feelings 1.99 10 5 11.1 -0.50 1.4e-01 ARL17A CENPW ERI1 FAM66A FBXO38 LRRC37A LRRC37A2 RP11-196G11.2 RP11-669E14.6 WNT3
Frequency of tenseness / restlessness in last 2 weeks 1.65 4 3 6.7 -1.00 6.6e-04 LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Hearing difficulty/problems with background noise 1.41 1 0 0.0 0.00 1.0e+00 RP11-669E14.6
Hair/balding pattern: Pattern 2 2.03 5 3 6.7 -0.99 9.3e-04 C10orf11 LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Had menopause 1.06 1 0 0.0 0.00 1.0e+00 RP11-73O6.3
Had other major operations 1.61 1 0 0.0 0.00 1.0e+00 PPA2
Forced vital capacity (FVC) 11.84 144 121 268.9 0.98 6.0e-110 ABHD12 AC073834.3 AC083843.1 AC103965.1 ACP2 ADCY3 AHI1 ANGPTL1 AOC1 AP3B1 ARFGEF2 ARHGAP1 ARL17A ASPSCR1 BOK BTBD1 C10orf11 C1QTNF4 C4orf14 C6orf106 C6orf126 CACFD1 CCDC87 CD79B CDC123 CDKN2C CDO1 CENPW CEP120 CLUAP1 CNPY2 COQ10A CRIPAK CTA-85E5.10 CTB-36H16.2 CTC-542B22.2 CTD-3076O17.1 CTNNB1 CTSS CYB561 DARS DCAF16 DHDDS DIRAS3 DLEU2 DNAJC9-AS1 EBPL EEF1G EFEMP1 ERCC6L2 FAM136A FAM26F FER FHL3 GALNT12 GDF5 GOLGA6L5 GSDMC GSK3A GSTCD H1FX H6PD HHIP-AS1 HTR4 ICAM2 IGHMBP2 IPO8 JAG1 KIAA1614 LOC147727 LONRF2 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAPK13 MDM4 MICAL3 MRPL42 MST1P2 MXD3 NFAT5 NOB1 NOSTRIN NSFP1 NUDT5 OTUD4 PAN2 PCDHB5 PLEKHM1P PNKD PPA2 PPIAL4C PSMA4 PSMC3 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RNF123 RP11-196G11.2 RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-669E14.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SEC24C SERPINF1 SLMAP SMARCD2 SMPD2 SNAI3-AS1 TCP11L1 TMED6 TP53INP2 TPD52L2 TRA2A TRIM38 TRIM63 TSEN15 TSPY26P TULP4 U91328.21 UBXN2A WHAMM WNT3 WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF438 ZNF500 ZNF76 ZSCAN2
Heel bone mineral density (BMD) T-score, automated (right) 2.59 15 9 20.0 -0.22 3.8e-01 ACP2 ARHGAP1 C4orf14 CRIPAK DLEU2 EBPL ERI1 FAM66A FHL3 HHIP-AS1 IGHMBP2 SAPS3 WNT4 ZBTB38 ZNF438
Ever unenthusiastic/disinterested for a whole week 1.34 3 0 0.0 0.00 1.0e+00 LRRC37A LRRC37A2 WNT3
Qualifications: None of the above 1.48 3 1 2.2 0.00 1.0e+00 PPA2 RAB5B RNF123
Mouth/teeth dental problems 1.04 1 0 0.0 0.00 1.0e+00 WNT3
Allergy 1.68 8 4 8.9 0.80 9.0e-03 AHI1 C6orf106 CNPY2 RAB5B SEC24C SLC22A4 TPD52L2 ZBTB38
Diabetes (self-reported) 1.72 2 0 0.0 0.00 1.0e+00 C1GALT1 CLUAP1
Fluid intelligence score 1.94 5 1 2.2 0.80 1.7e-02 C1QTNF4 DCAF16 PPA2 RNF123 U91328.21
Neuroticism score 2.28 9 7 15.6 -0.38 3.1e-01 C1QTNF4 ERI1 FAM66A FBXO38 LRRC37A LRRC37A2 RP11-196G11.2 RP11-669E14.6 WNT3
Weight 4.23 58 38 84.4 0.76 4.7e-14 ABHD12 AC103965.1 AP3B1 BOK C1QTNF4 C6orf106 CD79B CDKN2C CENPW CEP120 CRIPAK CTD-3076O17.1 CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERI1 FAM66A GDF5 GIPC2 GOLGA6L4 GOLGA6L5 H1FX HHIP-AS1 HTR4 IGHMBP2 LOC147727 MRPL42 MXD3 OTUD4 PPA2 PSMC5 RAB24 RAB5B RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 RPL10A SAPS3 SCMH1 SERPINF1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TPD52L2 TRA2A TRIM38 TRIM63 TSEN15 WNT4 ZBTB38 ZCCHC24 ZNF500 ZNF76 ZSCAN2
Impedance of arm (right) 2.58 33 28 62.2 0.16 3.5e-01 AC083843.1 AC103965.1 AOC1 ARL17A C5orf34 CD79B CENPW CEP120 CTD-3076O17.1 EEF1G EFEMP1 ERI1 FAM66A FER GOLGA6L4 GOLGA6L5 H6PD IGHMBP2 LOXL1-AS1 LRRC37A2 MRPL42 MST1P2 NSFP1 PSMC5 RAB5B RIN3 RP11-669E14.6 RP11-73O6.3 RPL10A SAPS3 SCMH1 WNT3 ZSCAN2
Arm fat percentage (right) 2.84 27 13 28.9 -0.64 1.1e-04 ABHD12 ACP2 ADCY3 AP3B1 ARFGEF2 ARL17A C1QTNF4 C6orf106 CCDC87 CD79B CENPW DCAF16 EEF1G ERI1 FAM66A HTR4 MAPK13 NFAT5 NOB1 NSFP1 PSMC3 PSMC5 RP11-196G11.2 RP11-78I14.1 SYNM TPD52L2 ZNF76
Trunk fat-free mass 7.34 78 65 144.4 0.92 4.1e-39 AC083843.1 ACP2 ADCY3 AOC1 AP3B1 ARFGEF2 BOK C1QTNF4 C6orf106 C6orf126 CD79B CDKN2C CENPW CEP120 CNPY2 COQ10A CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM136A FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 ICAM2 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MST1P2 MXD3 NOSTRIN OTUD4 PAN2 PLEKHM1P PNKD PPA2 PSMC3 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Hip circumference 3.52 40 29 64.4 0.45 1.6e-03 AC103965.1 ACP2 ADCY3 AP3B1 BOK C1QTNF4 C6orf106 CD79B CDKN2C CEP120 CTNNB1 DLEU2 EBPL EFEMP1 ERI1 FAM66A GDF5 GIPC2 GOLGA6L4 H1FX HHIP-AS1 HTR4 LOC147727 NOB1 OTUD4 PSMC3 RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 RPL10A SCMH1 SMPD2 TP53INP2 TPD52L2 TRIM38 WNT4 ZBTB38 ZNF500 ZSCAN2
Time employed in main current job 1.32 3 1 2.2 0.00 1.0e+00 LRRC37A2 RP11-669E14.6 WNT3
Father's age at death 1.46 3 1 2.2 0.00 1.0e+00 BTBD1 ERI1 PSMA4
Worrier / anxious feelings 1.90 6 5 11.1 -0.17 7.5e-01 ERI1 FAM66A LRRC37A2 RP11-196G11.2 RP11-669E14.6 WNT3
Frequency of tiredness / lethargy in last 2 weeks 1.42 1 0 0.0 0.00 1.0e+00 CCDC87
Hair/balding pattern: Pattern 3 2.59 5 5 11.1 0.74 1.5e-01 CENPW LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Number of live births 1.26 4 1 2.2 -0.98 2.0e-02 LRRC37A LRRC37A2 WNT3 WNT4
Forced expiratory volume in 1-second (FEV1) 13.05 166 142 315.6 1.00 2.3e-196 ABHD12 AC073834.3 AC083843.1 AC103965.1 ACP2 ADAM19 ADCY3 ADO AHI1 ANGPTL1 AOC1 AP3B1 ARFGEF2 ARHGAP1 ARL17A ASPSCR1 BOK BTBD1 C10orf11 C1GALT1 C1QTNF4 C4orf14 C5orf34 C6orf106 C6orf126 CACFD1 CARS2 CCDC87 CD79B CDC123 CDKN2C CDO1 CENPW CEP120 CLUAP1 CNPY2 COQ10A CRIPAK CTA-85E5.10 CTB-36H16.2 CTC-542B22.2 CTD-3076O17.1 CTNNB1 CTSS CYB561 DARS DCAF16 DENND2D DHDDS DIRAS3 DLEU2 DNAJC9-AS1 DNALI1 EBPL EEF1G EFEMP1 ERCC6L2 ERI1 FAM136A FAM168A FAM26F FAM66A FBXO38 FER FHL3 GALNT12 GDF5 GIPC2 GM2A GOLGA6L4 GOLGA6L5 GSDMC GSK3A GSTCD H1FX H6PD HESX1 HHIP-AS1 HTR4 ICAM2 IGHMBP2 IPO8 JAG1 KIAA1614 LOC147727 LONRF2 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAPK13 MDM4 METAP2 MICAL3 MRPL42 MST1P2 MXD3 NFAT5 NOB1 NOC3L NOSTRIN NSFP1 NUDT5 OTUD4 PCDHB5 PCGF2 PLEKHM1P PNKD PPA2 PPIAL4C PSMA4 PSMC3 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RNF123 RP11-196G11.2 RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-669E14.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE2 SCUBE3 SEC24C SERPINF1 SLC22A4 SLMAP SMARCD2 SMPD2 SNAI3-AS1 SOGA2 SYNM TCP11L1 THSD4 TMED6 TP53INP2 TPD52L2 TRA2A TRIM38 TRIM63 TSEN15 TSPY26P TULP4 U91328.21 UBXN2A WHAMM WNT3 WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF438 ZNF500 ZNF76 ZSCAN2
Pulse rate 1.31 4 2 4.4 -0.06 9.4e-01 CEP120 CTNNB1 EEF1G ZBTB38
Qualifications: A levels/AS levels or equivalent 1.33 2 0 0.0 0.00 1.0e+00 GDF5 RNF123
Mouth/teeth dental problems: Dentures 1.22 3 0 0.0 0.00 1.0e+00 ERI1 PSMA4 TRIM38
Asthma 2.53 11 7 15.6 -0.94 1.5e-06 ADAM19 AHI1 CNPY2 HTR4 RAB5B SCUBE3 SLC22A4 TPD52L2 TRIM38 U91328.21 ZNF76
Medication: Ibuprofen (e.g. Nurofen) 1.26 1 0 0.0 0.00 1.0e+00 U91328.21
Medication: Cholesterol lowering 1.28 2 0 0.0 0.00 1.0e+00 LOC147727 RP11-196G11.2
Lung cancer (father) 1.52 1 1 2.2 0.00 1.0e+00 PSMA4
Impedance of arm (left) 2.53 32 26 57.8 0.26 1.2e-01 AC103965.1 AOC1 ARL17A CD79B CENPW CEP120 CTD-3076O17.1 EEF1G EFEMP1 ERI1 FAM66A FER GOLGA6L4 GOLGA6L5 H6PD IGHMBP2 LOXL1-AS1 LRRC37A LRRC37A2 MRPL42 MST1P2 NSFP1 PSMC5 RAB5B RIN3 RP11-669E14.6 RP11-73O6.3 SAPS3 SCMH1 TSPY26P WNT3 ZSCAN2
Arm fat mass (right) 2.54 24 15 33.3 -0.13 5.1e-01 ABHD12 ACP2 ADCY3 AP3B1 C1QTNF4 C6orf106 CCDC87 CEP120 CTNNB1 ERI1 FAM66A HTR4 NOB1 OTUD4 PSMC3 RAB5B RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 TP53INP2 TPD52L2 TRIM38 ZBTB38 ZNF500
Trunk predicted mass 7.34 78 65 144.4 0.92 4.2e-39 AC083843.1 ACP2 ADCY3 AOC1 AP3B1 ARFGEF2 BOK C1QTNF4 C6orf106 C6orf126 CD79B CDKN2C CENPW CEP120 CNPY2 COQ10A CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM136A FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 ICAM2 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MST1P2 MXD3 NOSTRIN OTUD4 PAN2 PLEKHM1P PNKD PPA2 PSMC3 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Standing height 9.96 113 103 228.9 0.91 1.8e-51 AC083843.1 AC103965.1 ACP2 ADCY3 ADO AOC1 AP3B1 ARFGEF2 ARHGAP1 ARL17A ASPSCR1 BOK C1QTNF4 C4orf14 C6orf106 C6orf126 CACFD1 CCDC87 CD79B CDKN2C CDO1 CENPW CEP120 CNPY2 COQ10A CRIPAK CTC-542B22.2 CTD-3076O17.1 CTNNB1 CYB561 DCAF16 DHDDS DLEU2 DNALI1 EBPL EFEMP1 ERCC6L2 ERI1 FAM136A FAM26F FAM66A FER FHL3 GDF5 GIPC2 GOLGA6L4 GOLGA6L5 GSDMC GSK3A H1FX H6PD HHIP-AS1 ICAM2 IGHMBP2 IPO8 JAG1 KIAA1614 LOC147727 LOXL1-AS1 LRRC37A2 MRPL42 MST1P2 MXD3 NFAT5 NOB1 NOC3L NOSTRIN NSFP1 OTUD4 PAN2 PCDHB5 PLEKHM1P PNKD PPA2 PPIAL4C PSMC3 PSMC5 QSOX2 RAB24 RAD9A RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-669E14.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TMED6 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 U91328.21 UBXN2A WNT3 WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76 ZSCAN2
Tense / 'highly strung' 1.48 3 2 4.4 0.00 1.0e+00 ERI1 FAM66A RP11-196G11.2
Seen doctor (GP) for nerves, anxiety, tension or depression 1.56 2 0 0.0 0.00 1.0e+00 CCDC87 U91328.21
Hair/balding pattern: Pattern 4 4.16 10 9 20.0 0.35 3.2e-01 C10orf11 CENPW CTB-36H16.2 CTNNB1 FAM136A LRRC37A LRRC37A2 RP11-669E14.6 WNT3 ZBTB38
Birth weight of first child 2.96 14 7 15.6 0.95 5.7e-08 ARFGEF2 ASPSCR1 C6orf126 DCAF16 IPO8 MAPK13 NOC3L OTUD4 PPA2 RP11-78I14.1 RPL10A WNT4 ZBTB38 ZNF76
Peak expiratory flow (PEF) 7.24 58 33 73.3 0.97 4.2e-39 ADAM19 ARFGEF2 ARL17A ASPSCR1 BOK BTBD1 C10orf11 C1GALT1 C4orf14 C6orf106 CACFD1 CCDC87 CD79B CDC123 CDKN2C CTA-85E5.10 DCAF16 DHDDS DLEU2 DNALI1 EBPL EFEMP1 ERI1 FAM168A FAM66A FBXO38 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 HTR4 LOC147727 LOXL1-AS1 LRRC37A LRRC37A2 MDM4 METAP2 NOSTRIN NUDT5 OTUD4 PCGF2 PNKD PPA2 PSMC5 RAD9A RNF123 RP11-669E14.6 RPL10A SAPS3 SMPD2 THSD4 TP53INP2 TRIM63 UBXN2A WNT3 ZHX2 ZNF76
Blood clot in the leg (DVT) 1.43 1 1 2.2 0.00 1.0e+00 CACFD1
Medication: Paracetamol 1.84 5 5 11.1 -0.70 1.9e-01 LRRC37A LRRC37A2 RP11-669E14.6 U91328.21 WNT3
Headache pain in last month 1.92 6 5 11.1 -0.60 2.1e-01 LRRC37A LRRC37A2 RAB5B RP11-669E14.6 U91328.21 WNT3
Medication for cholesterol, blood pressure or diabetes 1.39 1 0 0.0 0.00 1.0e+00 TSPY26P
Gout (self-reported) 1.17 1 0 0.0 0.00 1.0e+00 U91328.21
Hypothyroidism/myxoedema (self-reported) 1.56 5 4 8.9 0.11 8.6e-01 AHI1 ERI1 FAM66A RAB5B ZNF76
Medication: Ventolin 100micrograms inhaler 1.67 1 0 0.0 0.00 1.0e+00 RAB5B
Birth weight 2.62 13 3 6.7 0.80 5.3e-04 C1QTNF4 C6orf126 CENPW CEP120 DCAF16 MAPK13 PPA2 RP11-73O6.3 TRA2A TULP4 UBXN2A WNT4 ZNF76
Chronic bronchitis/emphysema (mother) 1.69 2 1 2.2 0.00 1.0e+00 HHIP-AS1 PSMA4
High blood pressure (siblings) 1.49 1 0 0.0 0.00 1.0e+00 RP11-196G11.2
Forced vital capacity (FVC), Best measure 12.44 149 124 275.6 0.98 2.0e-115 ABHD12 AC073834.3 AC083843.1 AC103965.1 ACP2 ADCY3 ADO AHI1 ANGPTL1 AOC1 AP3B1 ARFGEF2 ARHGAP1 ARL17A ASPSCR1 BOK BTBD1 C10orf11 C1GALT1 C1QTNF4 C4orf14 C5orf34 C6orf106 C6orf126 CACFD1 CARS2 CCDC87 CD79B CDC123 CDKN2C CDO1 CENPW CEP120 CLUAP1 CNPY2 COQ10A CRIPAK CTA-85E5.10 CTB-36H16.2 CTC-542B22.2 CTD-3076O17.1 CTNNB1 CTSS CYB561 DARS DCAF16 DHDDS DIRAS3 DLEU2 DNAJC9-AS1 DNALI1 EBPL EEF1G EFEMP1 ERCC6L2 FAM136A FAM26F FER FHL3 GALNT12 GDF5 GOLGA6L5 GSDMC GSK3A GSTCD H1FX H6PD HHIP-AS1 HTR4 ICAM2 IGHMBP2 IPO8 JAG1 KIAA1614 LOC147727 LONRF2 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAPK13 MDM4 MICAL3 MRPL42 MST1P2 MXD3 NFAT5 NOB1 NOC3L NOSTRIN NSFP1 NUDT5 OTUD4 PAN2 PCDHB5 PLEKHM1P PNKD PPA2 PPIAL4C PSMA4 PSMC3 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RNF123 RP11-196G11.2 RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-669E14.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE2 SCUBE3 SEC24C SERPINF1 SMARCD2 SMPD2 SNAI3-AS1 TCP11L1 TMED6 TP53INP2 TPD52L2 TRA2A TRIM38 TRIM63 TSEN15 TULP4 U91328.21 UBXN2A WHAMM WNT3 WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF438 ZNF500 ZNF76 ZSCAN2
Body fat percentage 3.10 33 20 44.4 -0.37 2.0e-02 ABHD12 AC073834.3 AC103965.1 ACP2 ADCY3 AP3B1 ARFGEF2 C1QTNF4 C6orf106 CD79B CENPW CTD-3076O17.1 DARS DCAF16 EEF1G ERI1 GOLGA6L4 GOLGA6L5 GSK3A HTR4 MAPK13 NOB1 PSMC3 PSMC5 RIN3 RP11-196G11.2 RP11-78I14.1 SYNM TPD52L2 TRIM38 ZBTB38 ZNF500 ZSCAN2
Leg fat percentage (right) 2.97 29 17 37.8 -0.70 3.0e-06 ABHD12 AC073834.3 ACP2 ADCY3 ARFGEF2 C1QTNF4 C6orf106 CD79B CENPW DARS DCAF16 ERI1 GDF5 GOLGA6L4 GSK3A HTR4 MAPK13 NOB1 PLEKHM1P PSMC3 PSMC5 RIN3 RP11-196G11.2 SMARCD2 SNAI3-AS1 SYNM TPD52L2 TRIM38 ZSCAN2
Arm fat-free mass (right) 6.13 66 54 120.0 0.91 1.6e-30 AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C1QTNF4 C6orf106 CD79B CDKN2C CENPW CEP120 CNPY2 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PAN2 PNKD PPA2 PSMC5 RAB24 RAB5B RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Comparative body size at age 10 2.66 13 7 15.6 -0.53 3.4e-02 ACP2 ADCY3 AP3B1 ARL17A C1QTNF4 ERI1 FAM66A GOLGA6L4 NSFP1 PSMC3 RP11-196G11.2 SAPS3 U91328.21
Worry too long after embarrassment 1.75 6 0 0.0 0.05 9.2e-01 AHI1 ERI1 FAM66A PPA2 RP11-669E14.6 WNT3
Wheeze or whistling in the chest in last year 2.07 3 0 0.0 0.00 1.0e+00 ADAM19 CTC-542B22.2 TPD52L2
Health satisfaction 1.25 1 0 0.0 0.00 1.0e+00 CCDC87
Qualifications: College or University degree 1.62 11 7 15.6 0.76 4.1e-03 EEF1G GDF5 LRRC37A LRRC37A2 MDM4 PPA2 RAB5B RNF123 RP11-669E14.6 SMARCD2 WNT3
Medication for pain relief, constipation, heartburn 1.71 5 4 8.9 0.56 3.3e-01 LRRC37A LRRC37A2 RP11-669E14.6 U91328.21 WNT3
Medication: Blood pressure 1.59 2 1 2.2 0.00 1.0e+00 ERI1 TSPY26P
Medication: Seretide 50 evohaler 1.57 1 0 0.0 0.00 1.0e+00 SLC22A4
Mean time to correctly identify matches 1.73 3 2 4.4 0.00 1.0e+00 ARL17A NSFP1 SCUBE2
Whole body fat mass 2.97 32 25 55.6 0.21 2.0e-01 ABHD12 AC103965.1 ACP2 ADCY3 AP3B1 C1QTNF4 C6orf106 CEP120 CTD-3076O17.1 CTNNB1 EFEMP1 ERI1 GDF5 GOLGA6L4 GOLGA6L5 H1FX HTR4 MAPK13 NOB1 OTUD4 PSMC3 RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 SYNM TP53INP2 TPD52L2 TRIM38 ZBTB38 ZNF500 ZSCAN2
Leg fat mass (right) 2.56 27 14 31.1 -0.03 8.7e-01 ABHD12 ACP2 ADCY3 AP3B1 C1QTNF4 C6orf106 CTNNB1 DARS ERI1 FAM66A GIPC2 GOLGA6L4 GOLGA6L5 HTR4 NOB1 OTUD4 PSMC3 RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 SYNM TPD52L2 TRIM38 ZBTB38 ZNF500 ZSCAN2
Arm predicted mass (right) 6.07 66 52 115.6 0.91 1.8e-29 AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C1QTNF4 C6orf106 CD79B CDKN2C CENPW CEP120 CNPY2 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PNKD PPA2 PSMC5 RAB24 RAB5B RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 UBXN2A WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Pulse rate, automated reading 1.65 12 6 13.3 -0.52 5.4e-02 AC103965.1 BTBD1 C6orf106 CEP120 CTNNB1 DARS EEF1G PCGF2 RAB5B RP11-382A20.2 TRIM63 ZBTB38
Alcohol intake frequency. 1.77 9 8 17.8 -0.97 1.4e-06 C1QTNF4 LRRC37A LRRC37A2 PPA2 PSMC3 RP11-669E14.6 TMED6 UBXN2A WNT3
Comparative height size at age 10 8.38 85 67 148.9 0.90 8.0e-38 AC103965.1 ACP2 ADCY3 AOC1 AP3B1 ARFGEF2 ARHGAP1 ARL17A ASPSCR1 BOK C1QTNF4 C6orf106 CD79B CDKN2C CDO1 CENPW CEP120 CRIPAK CTD-3076O17.1 CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM136A FAM26F FER FHL3 GDF5 GOLGA6L4 GOLGA6L5 GSDMC H1FX H6PD HHIP-AS1 ICAM2 IPO8 KIAA1614 LOC147727 LOXL1-AS1 LRRC37A2 MICAL3 MRPL42 MST1P2 MXD3 NSFP1 OTUD4 PLEKHM1P PNKD PPA2 PPIAL4C PSMC3 PSMC5 QSOX2 RAB24 RAD9A RP11-250B2.6 RP11-669E14.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 U91328.21 UBXN2A WNT3 WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76 ZSCAN2
Suffer from 'nerves' 1.81 2 1 2.2 0.99 1.0e-02 C1QTNF4 FAM66A
Overall health rating 1.58 6 2 4.4 -0.69 1.3e-01 C6orf106 CCDC87 DCAF16 ERI1 HTR4 RP11-196G11.2
Leg pain on walking 1.25 1 0 0.0 0.00 1.0e+00 WNT3
Knee pain experienced in last month 1.71 3 2 4.4 0.00 1.0e+00 GDF5 LOC147727 RP11-196G11.2
Hypertension (Self-reported) 1.81 14 6 13.3 -0.86 3.6e-05 ACP2 ADO ARFGEF2 ARHGAP1 C1GALT1 DCAF16 ERI1 FAM66A HTR4 RP11-196G11.2 RP11-538P18.2 SLC22A4 TSPY26P U91328.21
Forced expiratory volume in 1-second (FEV1), predicted 7.65 48 33 73.3 0.97 2.5e-37 AC103965.1 ACP2 ADCY3 BOK C1QTNF4 C6orf106 CD79B CDKN2C CENPW CNPY2 CTD-3076O17.1 DCAF16 DLEU2 EBPL EFEMP1 FER GDF5 GOLGA6L4 GOLGA6L5 GSDMC H1FX HHIP-AS1 LOC147727 MRPL42 MST1P2 NOSTRIN OTUD4 PAN2 PSMC3 PSMC5 RAB24 RAD9A RP11-690I21.1 RP11-73O6.3 RP11-977G19.11 RPL10A SCMH1 SCUBE3 SLC22A4 SMARCD2 TP53INP2 TRA2A TSEN15 ZBTB38 ZHX2 ZNF500 ZNF76 ZSCAN2
Whole body fat-free mass 6.56 72 60 133.3 0.92 3.4e-35 AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C1QTNF4 C6orf106 CD79B CDKN2C CENPW CEP120 CNPY2 COQ10A CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PAN2 PLEKHM1P PNKD PPA2 PSMC3 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Leg fat-free mass (right) 5.39 61 49 108.9 0.90 4.0e-27 AC083843.1 AOC1 AP3B1 BOK C6orf106 CD79B CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERI1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PLEKHM1P PNKD PPA2 PSMC5 QSOX2 RAB5B RAD9A RIN3 RP11-250B2.6 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZNF500 ZNF76
Arm fat percentage (left) 2.94 25 14 31.1 -0.69 3.6e-05 ABHD12 ACP2 ADCY3 AP3B1 ARFGEF2 C1QTNF4 C6orf106 CCDC87 CD79B CENPW DCAF16 ERI1 FAM66A HTR4 MAPK13 NFAT5 NOB1 PSMC3 PSMC5 RP11-196G11.2 RP11-78I14.1 SYNM TPD52L2 TRIM38 ZNF76
Handedness (chirality/laterality): Left-handed 1.70 5 3 6.7 0.97 4.9e-03 ARL17A LRRC37A2 NSFP1 RP11-669E14.6 WNT3
Mood swings 1.86 5 5 11.1 -0.99 1.0e-03 FBXO38 LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Loneliness, isolation 1.52 3 1 2.2 0.66 2.2e-01 C1QTNF4 LRRC37A2 WNT3
Long-standing illness, disability or infirmity 1.31 1 0 0.0 0.00 1.0e+00 NOB1
Diabetes diagnosed by doctor 1.80 3 0 0.0 0.00 1.0e+00 C1GALT1 CENPW NOB1
Mouth/teeth dental problems: Mouth ulcers 1.68 5 5 11.1 -0.78 1.2e-01 CTSS LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Mineral and other dietary supplements 1.29 1 0 0.0 0.00 1.0e+00 NFAT5
Asthma (self-reported) 2.48 10 7 15.6 -0.94 5.5e-06 ADAM19 AHI1 CNPY2 HTR4 RAB5B SCUBE3 SLC22A4 TRIM38 U91328.21 ZNF76
Osteoporosis (self-reported) 1.52 1 1 2.2 0.00 1.0e+00 SAPS3
Osteoarthritis (self-reported) 1.26 1 0 0.0 0.00 1.0e+00 LOC147727
Smoking status: Current 1.44 1 0 0.0 0.00 1.0e+00 C1QTNF4
Forced expiratory volume in 1-second (FEV1), predicted percentage 7.02 54 31 68.9 0.98 7.8e-39 ABHD12 AC073834.3 ADAM19 ANGPTL1 ASPSCR1 BOK BTBD1 C10orf11 CDC123 CEP120 CLUAP1 CTA-85E5.10 CTSS DHDDS EEF1G ERI1 FAM168A FAM66A FBXO38 GSTCD HHIP-AS1 HTR4 JAG1 LRRC37A LRRC37A2 MICAL3 NOB1 NUDT5 PCGF2 PPA2 PSMA4 QSOX2 RIN3 RNF123 RP11-196G11.2 RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-669E14.6 RP11-967K21.1 RPL10A SEC24C SLMAP SMPD2 SOGA2 THSD4 TPD52L2 TRIM38 TRIM63 U91328.21 WHAMM WNT3 WNT4 ZNF76
Whole body water mass 6.53 72 61 135.6 0.92 3.2e-35 AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C1QTNF4 C6orf106 CD79B CDKN2C CENPW CEP120 CNPY2 COQ10A CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PAN2 PLEKHM1P PNKD PPA2 PSMC3 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Leg predicted mass (right) 5.40 62 49 108.9 0.90 1.9e-27 AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C6orf106 CD79B CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERI1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PLEKHM1P PNKD PPA2 PSMC5 QSOX2 RAB5B RAD9A RIN3 RP11-250B2.6 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZNF500 ZNF76
Arm fat mass (left) 2.57 27 16 35.6 -0.03 8.6e-01 ABHD12 ACP2 ADCY3 AP3B1 C1QTNF4 C6orf106 CCDC87 CEP120 CTNNB1 ERI1 FAM66A GDF5 GOLGA6L4 HTR4 NOB1 OTUD4 PSMC3 RAB5B RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 TP53INP2 TPD52L2 TRIM38 ZBTB38 ZNF500
Number of self-reported non-cancer illnesses 1.59 2 0 0.0 0.00 1.0e+00 CCDC87 SLC22A4
Average weekly champagne plus white wine intake 1.34 4 0 0.0 0.99 1.0e-02 LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Miserableness 1.60 6 5 11.1 -0.56 2.5e-01 ERI1 FAM66A LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Guilty feelings 1.72 6 0 0.0 -0.76 7.9e-02 CNPY2 LRRC37A LRRC37A2 RP11-669E14.6 UBXN2A WNT3
Medication: Blood pressure 1.72 5 2 4.4 0.05 9.3e-01 C1GALT1 ERI1 FAM66A LRRC37A2 RP11-669E14.6
Supplements: Fish oil (including cod liver oil) 1.43 2 0 0.0 0.00 1.0e+00 CCDC87 NFAT5
High cholesterol (Self-reported) 1.37 3 0 0.0 0.00 1.0e+00 FAM136A LOC147727 RP11-196G11.2
Medication: Bendroflumethiazide 1.49 2 0 0.0 0.00 1.0e+00 ERI1 FAM66A
Medication: Paracetamol 1.73 5 4 8.9 -0.78 1.2e-01 LRRC37A LRRC37A2 RP11-669E14.6 U91328.21 WNT3
Ever smoked 1.47 2 0 0.0 0.00 1.0e+00 C4orf14 PSMA4
Basal metabolic rate 6.00 69 53 117.8 0.90 4.0e-31 AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C6orf106 CD79B CDKN2C CENPW CEP120 CNPY2 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PAN2 PNKD PPA2 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76 ZSCAN2
Leg fat percentage (left) 2.97 31 17 37.8 -0.69 2.7e-06 ABHD12 AC073834.3 ACP2 ADCY3 ARFGEF2 C1QTNF4 C6orf106 CD79B CENPW DARS DCAF16 ERI1 GDF5 GIPC2 GOLGA6L4 GSK3A HTR4 MAPK13 NOB1 PLEKHM1P PSMC3 PSMC5 RIN3 RP11-196G11.2 SMARCD2 SYNM TPD52L2 TRIM38 UBXN2A ZNF76 ZSCAN2
Arm fat-free mass (left) 5.94 66 51 113.3 0.90 1.8e-29 AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C1QTNF4 C6orf106 CD79B CDKN2C CENPW CEP120 CNPY2 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PAN2 PNKD PPA2 PSMC5 RAB24 RAB5B RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Number of operations (self-reported) 1.69 1 1 2.2 0.00 1.0e+00 PPA2
Average weekly beer plus cider intake 1.61 1 0 0.0 0.00 1.0e+00 RNF123
Irritability 1.76 7 5 11.1 -0.33 4.6e-01 ERI1 FAM66A LRRC37A LRRC37A2 RP11-196G11.2 RP11-669E14.6 WNT3
Ever had prostate specific antigen (PSA) test 1.41 1 0 0.0 0.00 1.0e+00 ZBTB38
Fractured/broken bones in last 5 years 1.49 2 0 0.0 0.00 1.0e+00 CRIPAK WNT3
Diastolic blood pressure, automated reading 2.09 16 11 24.4 -0.17 5.2e-01 ADO BTBD1 CEP120 CTNNB1 DARS DCAF16 ERI1 FAM66A JAG1 MICAL3 RP11-538P18.2 SCMH1 SLMAP THSD4 U91328.21 ZNF76
Myopia 1.95 2 1 2.2 0.00 1.0e+00 ACP2 QSOX2
Vascular/heart problems diagnosed by doctor 1.73 12 7 15.6 0.85 2.2e-04 ACP2 ADO ARHGAP1 C1GALT1 DCAF16 ERI1 FAM66A NFAT5 RP11-196G11.2 RP11-538P18.2 SLC22A4 TSPY26P
Cholesterol lowering medication 1.48 1 0 0.0 0.00 1.0e+00 RP11-196G11.2
Pain experienced in last month 1.54 3 0 0.0 0.00 1.0e+00 CENPW RP11-196G11.2 RP11-669E14.6
Deep venous thrombosis (DVT) (self-reported) 1.37 1 1 2.2 0.00 1.0e+00 CACFD1
Heart disease (siblings) 1.29 1 0 0.0 0.00 1.0e+00 TP53INP2
Pack years of smoking 2.44 2 1 2.2 0.00 1.0e+00 CYB561 PSMA4
Impedance of whole body 2.78 39 27 60.0 0.13 4.3e-01 AC083843.1 AC103965.1 ADCY3 AOC1 C5orf34 CD79B CENPW CEP120 CTD-3076O17.1 EEF1G EFEMP1 ERI1 FAM66A GDF5 GOLGA6L4 GOLGA6L5 H6PD IGHMBP2 LOXL1-AS1 LRRC37A LRRC37A2 MRPL42 MST1P2 NSFP1 OTUD4 PPA2 PSMC5 RAB24 RAB5B RAD9A RIN3 RP11-382A20.2 RP11-669E14.6 RP11-73O6.3 SAPS3 SCMH1 SMPD2 WNT3 ZSCAN2
Leg fat mass (left) 2.51 27 15 33.3 -0.03 8.5e-01 ABHD12 ACP2 ADCY3 AP3B1 C1QTNF4 C6orf106 DARS ERI1 FAM66A GIPC2 GOLGA6L4 GOLGA6L5 HTR4 NOB1 OTUD4 PSMC3 RAB5B RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 SYNM TPD52L2 TRIM38 ZBTB38 ZNF500 ZSCAN2
Arm predicted mass (left) 5.87 65 50 111.1 0.90 2.1e-28 AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C6orf106 CD79B CDKN2C CENPW CEP120 CNPY2 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PAN2 PNKD PPA2 PSMC5 RAB24 RAB5B RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 50 1.43 3.3
GTEx Adipose Visceral Omentum 32 1.57 3.5
GTEx Adrenal Gland 13 0.89 3.1
GTEx Artery Aorta 38 1.28 3.5
GTEx Artery Coronary 20 1.69 3.8
GTEx Artery Tibial 43 1.14 3.3
GTEx Brain Caudate basal ganglia 10 1.09 3.3
GTEx Brain Cerebellar Hemisphere 20 1.34 3.5
GTEx Brain Cerebellum 23 1.16 3.4
GTEx Brain Cortex 23 2.22 3.7
GTEx Brain Frontal Cortex BA9 13 1.41 3.6
GTEx Brain Hippocampus 9 1.72 3.6
GTEx Brain Hypothalamus 14 2.37 3.9
GTEx Brain Nucleus accumbens basal ganglia 14 1.62 3.8
GTEx Brain Putamen basal ganglia 6 0.96 3.3
GTEx Breast Mammary Tissue 28 1.42 3.6
GTEx Breast Mammary Tissue (Male) 26 2.18 3.9
GTEx Breast Mammary Tissue (Female) 25 1.52 3.4
GTEx Cells EBV-transformed lymphocytes 28 1.97 3.7
GTEx Cells Transformed fibroblasts 54 1.29 3.3
GTEx Colon Sigmoid 23 1.57 3.6
GTEx Colon Transverse 28 1.36 3.4
GTEx Esophagus Gastroesophageal Junction 27 1.87 3.6
GTEx Esophagus Mucosa 47 1.42 3.4
GTEx Esophagus Muscularis 49 1.52 3.5
GTEx Heart Atrial Appendage 27 1.71 3.7
GTEx Heart Left Ventricle 21 1.37 3.5
GTEx Liver 13 1.81 3.5
GTEx Lung 44 1.53 3.4
GTEx Muscle Skeletal 33 1.14 3.3
GTEx Nerve Tibial 66 1.53 3.3
GTEx Ovary 18 1.98 4.2
GTEx Pancreas 26 1.59 3.4
GTEx Pituitary 25 2.24 3.7
GTEx Prostate 12 1.44 3.5
GTEx Skin Not Sun Exposed Suprapubic 42 1.71 3.4
GTEx Skin Sun Exposed Lower leg 52 1.43 3.5
GTEx Small Intestine Terminal Ileum 9 1.95 4.0
GTEx Spleen 20 1.42 3.5
GTEx Stomach 23 1.58 3.6
GTEx Testis 40 1.27 3.5
GTEx Thyroid 54 1.35 3.3
GTEx Uterus 9 1.59 4.1
GTEx Vagina 9 1.42 3.5
GTEx Whole Blood 33 1.66 3.2
METSIM Adipose 31 0.67 2.8
NTR Blood 19 0.79 2.8
ROSMAP Brain Pre-frontal Cortex 34 0.77 2.9
YFS Blood 41 0.89 2.8
CommonMind Brain Pre-frontal Cortex 45 0.84 2.8
The Cancer Genome Atlas Bladder Urothelial Carcinoma 17 1.03 3.0
The Cancer Genome Atlas Breast Invasive Carcinoma 48 1.09 2.8
The Cancer Genome Atlas Cervical Squamous Cell Carcinoma 14 1.28 3.3
The Cancer Genome Atlas Colon Adenocarcinoma 15 0.73 2.9
The Cancer Genome Atlas Esophageal Carcinoma 10 1.46 3.3
The Cancer Genome Atlas Glioblastoma Multiforme 18 1.76 3.3
The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma 30 1.10 3.0
The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma 49 1.20 2.9
The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma 15 0.73 2.8
The Cancer Genome Atlas Brain Lower Grade Glioma 47 1.09 2.9
The Cancer Genome Atlas Liver Hepatocellular Carcinoma 11 0.99 3.0
The Cancer Genome Atlas Lung Adenocarcinoma 43 1.46 3.1
The Cancer Genome Atlas Lung Squamous Cell Carcinoma 29 1.16 2.9
The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma 21 1.32 3.0
The Cancer Genome Atlas Pancreatic Adenocarcinoma 13 0.78 3.0
The Cancer Genome Atlas Pheochromocytoma and Paraganglioma 21 1.58 3.3
The Cancer Genome Atlas Prostate Adenocarcinoma 55 1.19 2.9
The Cancer Genome Atlas Rectum Adenocarcinoma 12 1.74 3.2
The Cancer Genome Atlas Soft Tissue Sarcoma 15 1.40 3.1
The Cancer Genome Atlas Skin Cutaneous Melanoma 7 1.31 3.3
The Cancer Genome Atlas Stomach Adenocarcinoma 17 1.01 2.9
The Cancer Genome Atlas Testicular Germ Cell Tumors 9 0.70 2.9
The Cancer Genome Atlas Thyroid Carcinoma 47 0.91 2.9
The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma 8 1.57 3.3