Hub : Traits :

Forced expiratory volume in 1-second (FEV1), Best measure

1980 significantly associated models · 411 unique genes.

Significant Loci

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	1	9049032	9576675	1	1	1.6e-07	4.2e-06	2.8e-04	38	H6PD
2	1	16273995	17989765	6	1	1.0e-09	2.1e-09	3.2e-01	97	MST1P2
3	1	22197336	22718991	1	1	3.4e-10	2.4e-11	2.0e-05	59	WNT4
4	1	25475418	27595862	8	2	4.0e-12	3.5e-12	2.6e-01	97	DHDDS TRIM63
5	1	37307281	38731622	4	2	1.6e-08	4.9e-08	1.0e+00	100	DNALI1 FHL3
6	1	40748755	42406344	2	1	5.0e-19	6.5e-15	7.2e-01	100	SCMH1
7	1	50735395	52135979	1	1	2.8e-07	3.7e-08	3.2e-02	85	CDKN2C
8	1	67814420	69212053	1	1	2.8e-08	4.8e-07	2.6e-01	95	DIRAS3
9	1	77655651	79300939	3	1	5.8e-09	1.1e-08	1.0e-01	92	GIPC2
10	1	111034818	112443281	1	1	1.4e-07	5.6e-08	1.0e+00	100	DENND2D
11	1	149672809	151659071	8	2	1.4e-09	1.6e-10	5.6e-03	81	CTSS PPIAL4C
12	1	178129899	179534540	1	1	7.4e-09	1.3e-10	4.8e-03	81	ANGPTL1
13	1	180186713	181614143	1	1	2.4e-07	1.5e-07	1.0e+00	100	KIAA1614
14	1	183325796	184739300	1	1	2.1e-07	2.8e-06	4.0e-01	97	TSEN15
15	1	203785948	205241659	1	1	3.7e-09	7.9e-08	1.1e-01	91	MDM4
16	2	23453834	25889403	5	2	1.5e-11	9.1e-13	3.5e-02	91	ADCY3 UBXN2A
17	2	36044351	37567226	3	1	2.6e-08	6.9e-08	4.2e-02	86	RP11-78I14.1
18	2	55401562	56843605	1	2	4.7e-26	1.5e-30	2.2e-02	96	EFEMP1
19	2	69829251	71228388	1	1	1.7e-07	4.1e-05	5.9e-01	98	FAM136A
20	2	100193898	101629737	1	1	8.7e-09	3.2e-10	1.1e-02	83	LONRF2
21	2	135898023	137435625	3	1	5.3e-11	1.5e-08	9.7e-03	79	DARS
22	2	168949234	170419444	1	1	3.3e-08	2.8e-09	1.5e-06	34	NOSTRIN
23	2	177559549	179175022	3	1	5.7e-11	1.1e-08	5.7e-01	99	AC073834.3
24	2	218300530	219878756	2	1	2.9e-10	2.3e-11	5.0e-08	34	PNKD
25	2	231967886	233349588	1	1	2.0e-10	4.2e-10	4.4e-01	98	RP11-690I21.1
26	2	241805851	243048760	1	1	4.8e-17	6.3e-15	6.3e-01	100	BOK
27	3	40537829	41986787	1	1	2.6e-08	1.3e-07	8.5e-01	100	CTNNB1
28	3	48618666	50620043	12	1	3.4e-10	9.1e-08	5.9e-03	74	RNF123
29	3	56629678	58613378	3	2	1.6e-08	1.0e-10	7.3e-03	83	HESX1 SLMAP
30	3	128334272	129714372	1	1	5.2e-09	3.2e-09	4.9e-03	77	H1FX
31	3	140350567	141867638	1	1	1.4e-09	1.1e-09	1.0e+00	100	ZBTB38
32	3	157125828	159106064	3	1	9.3e-12	1.7e-10	3.2e-01	98	RP11-538P18.2
33	4	686563	2058475	1	1	5.9e-08	2.7e-06	1.7e-01	92	CRIPAK
34	4	2825660	4219590	1	1	2.3e-08	9.8e-07	4.8e-03	67	LRPAP1
35	4	17104059	18507692	2	1	3.2e-36	5.7e-31	1.7e-03	93	DCAF16
36	4	57080198	58531645	4	1	3.8e-09	3.1e-09	1.0e+00	100	C4orf14
37	4	105373669	107622327	5	3	5.6e-26	1.7e-29	7.6e-02	98	GSTCD PPA2
38	4	144230902	146788825	4	2	1.1e-30	6.0e-40	6.1e-08	83	HHIP-AS1 OTUD4
39	5	43243774	43940059	2	1	9.5e-08	5.4e-06	9.0e-01	100	C5orf34
40	5	77052232	78753539	2	1	6.1e-10	1.1e-12	4.4e-04	76	AP3B1
41	5	107390303	109224099	1	1	3.0e-08	5.5e-07	1.9e-02	78	FER
42	5	114443019	115851911	1	1	1.5e-07	1.7e-06	8.0e-01	100	CDO1
43	5	121480516	123002130	2	2	7.3e-11	8.4e-13	9.4e-03	87	CEP120 CTB-36H16.2
44	5	130936652	132401730	4	1	3.4e-08	2.7e-07	3.5e-02	83	SLC22A4
45	5	139323257	141214127	11	1	5.7e-10	6.7e-08	4.5e-01	98	PCDHB5
46	5	147012186	148712150	3	2	4.5e-21	2.3e-26	5.6e-04	90	FBXO38 HTR4
47	5	149903130	151338753	1	1	1.1e-07	2.3e-06	4.3e-01	97	GM2A
48	5	156009720	157697754	2	1	1.1e-15	1.8e-13	3.7e-04	77	ADAM19
49	5	176040488	177260129	2	2	7.2e-09	5.5e-09	3.2e-02	86	MXD3 RAB24
50	6	25266147	26689223	2	3	8.5e-12	3.4e-14	2.9e-01	98	TRIM38 U91328.21
51	6	33745071	36804187	14	10	7.8e-27	1.1e-23	NaN	NaN	C6orf106 C6orf126 MAPK13 RPL10A SCUBE3 ZNF76
52	6	80120201	81763771	2	1	1.7e-09	1.2e-09	1.0e+00	100	RP11-250B2.6
53	6	108994161	110843638	9	1	1.2e-13	8.3e-14	5.7e-08	47	SMPD2
54	6	115880851	117481404	3	1	6.4e-09	5.8e-08	2.4e-02	83	FAM26F
55	6	125970401	127355237	1	1	5.2e-16	2.9e-19	1.2e-04	82	CENPW
56	6	129638583	131163098	2	1	4.6e-17	5.5e-23	8.0e-14	43	RP11-73O6.3
57	6	134905567	136516257	1	1	2.2e-07	1.1e-06	2.1e-01	93	AHI1
58	6	158487143	159178345	1	1	2.3e-08	8.0e-08	4.6e-03	72	TULP4
59	7	6502367	7988091	1	1	9.0e-10	9.9e-09	1.3e-02	81	C1GALT1
60	7	23296533	23818538	1	1	1.5e-08	3.9e-11	3.4e-04	71	TRA2A
61	7	149847287	151252618	1	1	1.3e-07	5.3e-08	7.2e-03	76	AOC1
62	8	8092025	9669775	2	1	2.9e-08	1.3e-07	2.5e-02	82	ERI1
63	8	11527910	12966739	1	1	1.3e-07	5.9e-07	7.6e-02	87	FAM66A
64	8	123101743	124679448	1	1	1.4e-08	2.0e-10	2.7e-03	78	ZHX2
65	8	130517157	131045893	1	1	1.3e-15	2.3e-13	6.8e-01	100	GSDMC
66	8	135106207	136500554	1	1	1.1e-09	2.2e-10	3.3e-02	89	AC083843.1
67	9	97945796	99474182	1	1	1.2e-07	4.6e-07	2.9e-07	-4	ERCC6L2
68	9	100871717	102304304	1	1	3.1e-07	2.5e-05	5.8e-03	57	GALNT12
69	9	135629944	137034272	1	1	4.9e-08	1.0e-11	2.6e-05	62	CACFD1
70	9	138403706	139836362	1	1	2.4e-16	3.7e-14	6.6e-01	100	QSOX2
71	10	11515875	13569805	3	2	1.3e-20	1.8e-24	2.7e-04	87	CDC123 NUDT5
72	10	30435876	32016090	1	1	1.3e-08	6.8e-08	4.9e-02	87	ZNF438
73	10	63870456	65606229	2	1	2.0e-09	2.1e-09	4.5e-02	89	ADO
74	10	74317852	76323150	8	2	5.5e-10	8.8e-10	5.6e-01	99	DNAJC9-AS1 SEC24C
75	10	76664253	79018276	1	1	2.3e-12	2.3e-16	1.2e-05	71	C10orf11
76	10	80443273	81901722	1	1	1.3e-07	1.2e-06	4.8e-06	12	ZCCHC24
77	10	95379543	96818402	1	1	3.4e-08	1.4e-07	6.0e-01	99	NOC3L
78	11	8348340	9847690	1	1	1.1e-08	9.5e-07	9.9e-01	100	SCUBE2
79	11	32812529	33376095	1	1	2.0e-07	9.3e-07	4.2e-01	97	TCP11L1
80	11	46010847	48360648	11	7	1.4e-09	9.2e-10	1.0e+00	100	ACP2 ARHGAP1 C1QTNF4 PSMC3
81	11	61627881	63110149	7	1	2.4e-11	1.0e-10	5.1e-01	99	EEF1G
82	11	65594820	69476279	8	4	1.5e-24	1.0e-22	1.0e+00	100	CCDC87 IGHMBP2 RAD9A SAPS3
83	11	72399607	74006925	4	1	1.5e-10	9.3e-09	1.9e-01	95	FAM168A
84	12	27616589	29042392	1	1	1.7e-10	5.1e-10	2.4e-01	96	RP11-967K21.1
85	12	30084002	31526510	1	1	7.1e-09	2.0e-09	1.0e+00	100	IPO8
86	12	55633142	57684978	13	7	1.1e-11	1.2e-10	NaN	NaN	CNPY2 COQ10A PAN2 RAB5B RP11-977G19.11
87	12	93165619	94589220	1	1	4.7e-09	4.3e-16	1.1e-09	44	MRPL42
88	12	95167773	96606889	1	1	3.8e-08	5.6e-06	1.7e-01	91	METAP2
89	13	49557805	51390447	4	6	1.2e-14	1.3e-14	1.0e+00	100	DLEU2 EBPL
90	13	110598964	112060514	1	1	2.6e-07	2.1e-07	6.2e-02	87	CARS2
91	14	92286262	93847625	1	1	1.7e-12	8.5e-13	1.0e+00	100	RIN3
92	15	70697945	72771648	1	1	3.5e-09	1.3e-11	1.1e-04	67	THSD4
93	15	73524629	74915888	1	1	4.4e-10	5.7e-17	5.8e-09	52	LOXL1-AS1
94	15	78032707	79537269	5	1	2.0e-12	1.9e-13	2.8e-02	91	PSMA4
95	15	82250003	85883064	18	11	1.5e-16	2.2e-29	NaN	NaN	AC103965.1 BTBD1 GOLGA6L4 GOLGA6L5 RP11-382A20.2 WHAMM ZSCAN2
96	15	98944630	101209341	3	2	1.0e-09	2.2e-11	7.2e-08	35	CTD-3076O17.1 SYNM
97	16	2741812	5510848	9	2	2.8e-12	1.3e-11	4.3e-03	82	CLUAP1 ZNF500
98	16	30154740	31833122	15	1	6.2e-13	3.4e-11	3.2e-01	98	RP11-196G11.2
99	16	68681792	71093625	10	3	1.6e-13	6.3e-16	3.9e-01	99	NFAT5 NOB1 TMED6
100	16	88030355	89448663	2	1	4.5e-09	2.5e-08	6.0e-03	76	SNAI3-AS1
101	17	923916	2420934	3	1	4.9e-10	3.5e-09	2.8e-01	97	SERPINF1
102	17	29482878	31275580	6	1	1.8e-08	1.9e-08	1.4e-01	93	CTC-542B22.2
103	17	36211659	37597185	1	1	2.1e-09	2.7e-09	1.0e+00	100	PCGF2
104	17	42774693	45876022	23	6	3.5e-31	1.8e-27	1.0e+00	100	ARL17A LRRC37A LRRC37A2 NSFP1 RP11-669E14.6 WNT3
105	17	60821100	63531331	17	7	3.6e-22	1.2e-19	1.0e+00	100	CD79B CYB561 ICAM2 PLEKHM1P PSMC5 SMARCD2
106	17	79202465	80694826	8	1	7.4e-16	1.5e-14	1.0e-01	96	ASPSCR1
107	18	8010444	9532097	1	1	4.6e-09	2.2e-09	3.2e-02	87	SOGA2
108	19	10068513	11873382	4	1	1.1e-09	3.3e-11	2.8e-03	80	LOC147727
109	19	42489516	42990382	1	1	2.7e-08	1.6e-08	4.9e-02	88	GSK3A
110	20	9925555	11347455	1	1	5.3e-10	2.9e-10	8.4e-04	72	JAG1
111	20	24485525	26307797	7	1	2.2e-08	3.2e-08	8.0e-02	90	ABHD12
112	20	30060562	31870640	4	1	3.3e-08	1.6e-08	1.0e+00	100	TSPY26P
113	20	32603830	34288854	5	2	1.1e-10	1.4e-08	7.7e-01	100	GDF5 TP53INP2
114	20	46838455	48591758	5	1	4.5e-12	1.1e-12	1.3e-02	88	ARFGEF2
115	20	61636050	62912463	5	1	6.0e-11	6.0e-10	2.1e-02	86	TPD52L2
116	22	17581838	19203078	1	1	1.3e-11	2.7e-10	1.8e-01	96	MICAL3
117	22	29707908	31171274	2	1	2.4e-11	2.3e-13	6.9e-04	79	CTA-85E5.10

Pleiotropic Associations

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr	corr P	genes
Bipolar Disorder (2018)	1.54	3	0	0.0	-0.97	2.5e-02	AC103965.1 LOC147727 ZSCAN2
Bipolar Disorder or Schizophrenia	1.89	8	3	6.7	-0.51	1.3e-01	AC103965.1 GOLGA6L4 GOLGA6L5 PCDHB5 PSMA4 TRIM38 U91328.21 ZSCAN2
Depressed Affect (Nagel 2018)	2.04	6	4	8.9	-0.68	1.4e-01	C1QTNF4 LRRC37A LRRC37A2 RP11-196G11.2 RP11-669E14.6 WNT3
Depression (Nagel 2018)	1.53	1	0	0.0	0.00	1.0e+00	WNT3
Intelligence (Savage-Jansen 2018)	1.80	14	9	20.0	0.90	9.1e-07	ACP2 ARL17A C1QTNF4 CENPW CTNNB1 DCAF16 DLEU2 NSFP1 PCDHB5 PPA2 RNF123 TULP4 UBXN2A WNT3
Neuroticism (Nagel 2018)	2.34	11	7	15.6	-0.68	2.1e-02	ARL17A C1QTNF4 CENPW FBXO38 LRRC37A LRRC37A2 NSFP1 RP11-196G11.2 RP11-669E14.6 U91328.21 WNT3
Schizophrenia (2018)	1.69	6	3	6.7	-0.44	2.8e-01	AC103965.1 PCDHB5 PSMA4 TRIM38 U91328.21 ZSCAN2
Worry (Nagel 2018)	1.92	9	5	11.1	-0.84	5.0e-03	ARL17A CENPW FBXO38 LRRC37A LRRC37A2 NSFP1 RP11-196G11.2 RP11-669E14.6 WNT3
Alzheimer’s Disease (including proxy)	1.18	1	0	0.0	0.00	1.0e+00	RP11-196G11.2
Crohns Disease (2017)	1.35	5	4	8.9	0.29	6.4e-01	ADCY3 ADO SLC22A4 TPD52L2 ZBTB38
Irritable Bowel Disease (IBD)	1.27	5	3	6.7	0.00	1.0e+00	ADCY3 ADO CTSS SLC22A4 TPD52L2
Ulcerative Colitis (UC)	1.10	2	0	0.0	0.00	1.0e+00	RNF123 SLC22A4
Reaction Time	1.72	4	2	4.4	-0.94	5.7e-02	ARL17A LOC147727 NSFP1 SCUBE2
Verbal and Numeric Reasoning (VNR)	2.00	8	6	13.3	0.67	2.3e-02	C1QTNF4 CENPW DCAF16 PPA2 RNF123 TULP4 U91328.21 UBXN2A
Breast Cancer	1.57	9	8	17.8	-0.48	1.9e-01	ADCY3 LRRC37A LRRC37A2 RIN3 RP11-669E14.6 RP11-73O6.3 SLC22A4 WNT3 ZBTB38
Ovarian Cancer	1.70	5	4	8.9	0.81	9.8e-02	DNALI1 LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Prostate Cancer	1.58	1	1	2.2	0.00	1.0e+00	MDM4
Age at First Birth	1.04	1	0	0.0	0.00	1.0e+00	ABHD12
Body Mass Index (BMI) (2010)	1.89	4	2	4.4	-0.99	3.7e-05	ACP2 ADCY3 C1QTNF4 PSMC3
Crohns Disease (2012)	1.49	3	2	4.4	0.00	1.0e+00	ADO SLC22A4 TPD52L2
HDL Cholesterol	2.23	5	4	8.9	0.81	1.5e-02	ACP2 ARHGAP1 C1QTNF4 C6orf106 PSMC3
LDL Cholesterol	1.22	2	1	2.2	0.00	1.0e+00	CACFD1 LOC147727
Lupus	1.47	1	0	0.0	0.00	1.0e+00	ZNF76
Neuroticism (2016)	1.88	4	3	6.7	-0.74	2.6e-01	FAM66A LRRC37A2 RP11-669E14.6 WNT3
Primary Biliary Cirrhosis	1.71	3	0	0.0	0.00	1.0e+00	LRRC37A RP11-669E14.6 WNT3
Schizophrenia (2014)	1.48	3	1	2.2	-0.99	1.3e-02	AC103965.1 GOLGA6L5 H1FX
Triglycerides	1.27	2	0	0.0	0.00	1.0e+00	FAM66A RP11-196G11.2
Blood Eosinophil Count	1.95	34	22	48.9	-0.30	6.3e-02	AC103965.1 AHI1 ARL17A C4orf14 C5orf34 CACFD1 CNPY2 CTSS DLEU2 EBPL FAM136A FAM26F GSK3A HTR4 KIAA1614 LRRC37A LRRC37A2 MAPK13 NOB1 NOSTRIN PCGF2 RAB5B RIN3 RP11-669E14.6 RP11-73O6.3 RPL10A SEC24C SLC22A4 SMPD2 TRIM63 TSPY26P WNT3 ZNF76 ZSCAN2
Blood Platelet Count	1.46	41	30	66.7	-0.35	1.8e-02	ABHD12 AC103965.1 ACP2 ADO ARL17A C1QTNF4 C4orf14 C6orf106 CACFD1 CEP120 CNPY2 CTSS DCAF16 DENND2D FAM136A FER GIPC2 GOLGA6L4 HESX1 HTR4 KIAA1614 LOC147727 LRRC37A LRRC37A2 NSFP1 OTUD4 PNKD PPA2 PSMC3 RIN3 RP11-669E14.6 SCMH1 SLC22A4 SLMAP SMARCD2 SMPD2 TPD52L2 TULP4 ZCCHC24 ZHX2 ZSCAN2
Blood Red Count	2.18	27	19	42.2	-0.34	6.7e-02	AC103965.1 AOC1 ASPSCR1 C6orf106 CACFD1 CCDC87 CD79B CENPW COQ10A DARS FAM136A LRRC37A LRRC37A2 MST1P2 NFAT5 NOB1 PAN2 PSMC5 RAD9A RP11-196G11.2 RP11-669E14.6 RP11-73O6.3 RP11-977G19.11 SMPD2 SNAI3-AS1 WNT3 ZBTB38
Blood White Count	2.05	39	28	62.2	-0.60	6.9e-06	ACP2 ADO AHI1 C1QTNF4 C4orf14 C5orf34 C6orf106 CACFD1 CENPW CEP120 CTB-36H16.2 DCAF16 EBPL FBXO38 FER GM2A GSK3A HTR4 KIAA1614 LRRC37A MICAL3 NOB1 NOSTRIN PCDHB5 PNKD PSMC3 RIN3 RP11-669E14.6 RP11-73O6.3 SCMH1 SCUBE3 SLC22A4 SMARCD2 SMPD2 TRA2A TULP4 UBXN2A ZHX2 ZNF76
Heel T-Score	3.22	53	39	86.7	-0.03	8.2e-01	AC103965.1 ACP2 ADCY3 ARHGAP1 ARL17A ASPSCR1 C4orf14 CACFD1 CDKN2C CEP120 CRIPAK CTA-85E5.10 CTB-36H16.2 CTNNB1 CTSS DCAF16 DIRAS3 DLEU2 EBPL EEF1G FHL3 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 JAG1 KIAA1614 LRRC37A LRRC37A2 NSFP1 PLEKHM1P PSMC3 RAB24 RP11-196G11.2 RP11-669E14.6 RP11-73O6.3 RP11-967K21.1 RPL10A SAPS3 SCMH1 SLMAP SMARCD2 SNAI3-AS1 THSD4 TULP4 WHAMM WNT3 WNT4 ZBTB38 ZCCHC24 ZNF438 ZNF76
BMI	2.19	31	19	42.2	-0.38	2.0e-02	ACP2 ADCY3 AP3B1 ARFGEF2 C1QTNF4 C6orf106 CEP120 CTNNB1 DCAF16 GIPC2 GSDMC GSK3A HTR4 IGHMBP2 LOXL1-AS1 MST1P2 NFAT5 NOB1 OTUD4 PSMC3 RAB24 RAB5B RNF123 RP11-196G11.2 RP11-538P18.2 RP11-73O6.3 SAPS3 SMARCD2 TMED6 TSPY26P ZNF500
Height	9.96	124	115	255.6	0.88	2.5e-46	AC083843.1 AC103965.1 ACP2 ADCY3 ADO AHI1 AOC1 AP3B1 ARFGEF2 ARHGAP1 ARL17A ASPSCR1 BOK C10orf11 C1QTNF4 C4orf14 C6orf106 C6orf126 CACFD1 CCDC87 CD79B CDC123 CDKN2C CDO1 CENPW CEP120 CLUAP1 CNPY2 COQ10A CRIPAK CTA-85E5.10 CTC-542B22.2 CTD-3076O17.1 CTNNB1 CTSS CYB561 DCAF16 DHDDS DIRAS3 DLEU2 DNAJC9-AS1 DNALI1 EBPL EFEMP1 ERCC6L2 FAM136A FAM26F FER FHL3 GDF5 GIPC2 GOLGA6L4 GOLGA6L5 GSDMC GSK3A H1FX H6PD HHIP-AS1 ICAM2 IGHMBP2 IPO8 JAG1 KIAA1614 LOC147727 LOXL1-AS1 LRRC37A LRRC37A2 MAPK13 MDM4 MICAL3 MRPL42 MST1P2 MXD3 NFAT5 NOB1 NOC3L NOSTRIN NSFP1 OTUD4 PAN2 PCDHB5 PLEKHM1P PNKD PPA2 PPIAL4C PSMC3 PSMC5 QSOX2 RAB24 RAD9A RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-669E14.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TMED6 TP53INP2 TPD52L2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT3 WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76 ZSCAN2
Waist Hip Ratio (WHR)	2.59	32	21	46.7	-0.45	6.4e-03	AC103965.1 ADCY3 AP3B1 ASPSCR1 C6orf106 CD79B CENPW CLUAP1 DENND2D DLEU2 EBPL EEF1G GDF5 GIPC2 GOLGA6L5 HHIP-AS1 LOC147727 LRRC37A LRRC37A2 NFAT5 NSFP1 OTUD4 PSMC5 RAB24 RAD9A RP11-669E14.6 RP11-73O6.3 SCUBE2 WNT3 WNT4 ZBTB38 ZSCAN2
Systolic Blood Pressure	1.75	31	17	37.8	-0.34	5.7e-02	ADCY3 ADO ARFGEF2 ARHGAP1 ARL17A C1QTNF4 CARS2 CDC123 CEP120 DCAF16 EFEMP1 FBXO38 FER FHL3 GDF5 GIPC2 HTR4 LRRC37A2 MICAL3 NSFP1 NUDT5 PCDHB5 PLEKHM1P PNKD RIN3 RP11-538P18.2 RP11-669E14.6 RPL10A ZHX2 ZNF500 ZNF76
Smoking Status	1.48	3	0	0.0	0.00	1.0e+00	CNPY2 NOB1 WNT3
Allergy or Eczema	1.56	5	4	8.9	-0.62	1.9e-01	AHI1 C6orf106 RAB5B SLC22A4 ZBTB38
Cardiovascular Disease	1.47	12	5	11.1	-0.84	3.4e-04	ACP2 ADO ARHGAP1 C1GALT1 DCAF16 HTR4 MXD3 RP11-196G11.2 RP11-538P18.2 SLC22A4 SMARCD2 TSPY26P
Hypothyroidism (self reported)	1.34	3	2	4.4	0.00	1.0e+00	AHI1 RAB5B RIN3
Respiratory disease	2.31	11	6	13.3	-0.95	7.3e-07	ADAM19 AHI1 C4orf14 CNPY2 HTR4 RAB5B SCUBE3 SEC24C SLC22A4 TPD52L2 ZNF76
Type 2 Diabetes (T2D) (2018)	1.74	5	1	2.2	-0.65	2.4e-01	C1GALT1 CENPW HTR4 NOB1 NUDT5
Lung FEV1/FVC ratio	8.13	63	50	111.1	0.74	2.7e-13	AC103965.1 ADAM19 ADCY3 ADO BTBD1 C10orf11 C1GALT1 C4orf14 C6orf106 CDC123 CDKN2C CENPW CEP120 CNPY2 CTA-85E5.10 CTC-542B22.2 CTNNB1 DENND2D DNAJC9-AS1 DNALI1 EEF1G EFEMP1 FAM168A FBXO38 GDF5 GIPC2 GM2A GOLGA6L4 GOLGA6L5 GSTCD HESX1 HHIP-AS1 HTR4 LONRF2 LRRC37A LRRC37A2 METAP2 MICAL3 MST1P2 NUDT5 OTUD4 PCGF2 PLEKHM1P PPA2 PSMA4 RAB5B RP11-382A20.2 RP11-669E14.6 RPL10A SCUBE2 SCUBE3 SEC24C SLC22A4 SLMAP SMPD2 SOGA2 SYNM THSD4 TSPY26P WHAMM ZBTB38 ZNF76 ZSCAN2
Lung FVC	6.80	102	75	166.7	0.87	6.9e-33	ABHD12 AC073834.3 ACP2 AHI1 ANGPTL1 AOC1 AP3B1 ARFGEF2 ARL17A ASPSCR1 BOK BTBD1 C10orf11 C1GALT1 C4orf14 C5orf34 C6orf106 C6orf126 CACFD1 CCDC87 CD79B CDC123 CENPW CEP120 CLUAP1 CTA-85E5.10 CTB-36H16.2 CTSS DARS DCAF16 DHDDS DIRAS3 EBPL EEF1G EFEMP1 FAM136A FAM26F FBXO38 GALNT12 GDF5 GM2A GSDMC GSK3A GSTCD HTR4 IGHMBP2 IPO8 JAG1 KIAA1614 LONRF2 LRPAP1 LRRC37A LRRC37A2 MAPK13 MDM4 MICAL3 MST1P2 NFAT5 NOB1 NSFP1 NUDT5 PCDHB5 PLEKHM1P PPA2 PPIAL4C PSMA4 PSMC5 QSOX2 RAB5B RAD9A RIN3 RNF123 RP11-196G11.2 RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-669E14.6 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RPL10A SAPS3 SCMH1 SEC24C SLC22A4 SLMAP SMPD2 SNAI3-AS1 SOGA2 TCP11L1 THSD4 TPD52L2 TRIM63 TSPY26P TULP4 UBXN2A WHAMM WNT3 WNT4 ZBTB38 ZNF438 ZNF76
Neuroticism	2.23	10	6	13.3	-0.73	1.6e-02	ARL17A C1QTNF4 CENPW FBXO38 LRRC37A LRRC37A2 NSFP1 RP11-196G11.2 RP11-669E14.6 WNT3
Chronotype (morning person)	1.46	6	0	0.0	-1.00	4.0e-06	ACP2 C1QTNF4 CRIPAK CTSS CYB561 LOC147727
Hair Pigment	0.70	21	16	35.6	0.15	5.0e-01	ACP2 ARHGAP1 ASPSCR1 BTBD1 C1QTNF4 C4orf14 CCDC87 FAM136A GDF5 IGHMBP2 LOC147727 LRRC37A LRRC37A2 RP11-669E14.6 RP11-73O6.3 SAPS3 SNAI3-AS1 TP53INP2 TULP4 ZBTB38 ZNF76
Tanning	0.82	9	8	17.8	0.38	3.1e-01	ADCY3 ADO CTSS GDF5 MAPK13 METAP2 MXD3 SNAI3-AS1 TP53INP2
Hand grip strength (left)	4.13	34	21	46.7	0.97	9.7e-23	ACP2 ADCY3 AOC1 ARFGEF2 C1QTNF4 C6orf106 CCDC87 CD79B CRIPAK CYB561 DARS DCAF16 FER GDF5 H1FX IGHMBP2 JAG1 LOXL1-AS1 LRRC37A LRRC37A2 NOB1 PSMC3 PSMC5 RAD9A RP11-250B2.6 RP11-669E14.6 RP11-73O6.3 SAPS3 SLC22A4 TRA2A WNT3 ZBTB38 ZCCHC24 ZNF76
Number of treatments/medications taken	1.43	1	0	0.0	0.00	1.0e+00	DCAF16
Sensitivity / hurt feelings	2.22	5	4	8.9	-1.00	1.5e-04	ARL17A LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Frequency of depressed mood in last 2 weeks	1.52	1	0	0.0	0.00	1.0e+00	WNT3
Relative age of first facial hair	2.42	6	5	11.1	-0.78	4.0e-02	C6orf106 LRRC37A LRRC37A2 RP11-669E14.6 WNT3 ZBTB38
Systolic blood pressure, automated reading	2.17	21	7	15.6	-0.48	2.9e-02	ADCY3 ADO ARHGAP1 DCAF16 EFEMP1 ERI1 FAM66A FBXO38 FER FHL3 HTR4 LRRC37A2 NSFP1 NUDT5 PPA2 RP11-538P18.2 RP11-669E14.6 RPL10A U91328.21 ZHX2 ZNF76
Medication: Metformin	1.70	2	0	0.0	0.00	1.0e+00	C1QTNF4 NUDT5
Diabetes (mother)	1.52	1	1	2.2	0.00	1.0e+00	NUDT5
Pack years adult smoking proportion	2.51	2	1	2.2	0.00	1.0e+00	CYB561 PSMA4
Impedance of leg (right)	2.90	35	23	51.1	0.12	4.9e-01	AC103965.1 ADCY3 AOC1 AP3B1 C1QTNF4 C5orf34 C6orf106 CD79B CDO1 CEP120 CTD-3076O17.1 CTSS ERI1 FAM66A GDF5 GOLGA6L4 GOLGA6L5 H1FX IGHMBP2 LOXL1-AS1 MST1P2 OTUD4 PSMC5 RAB24 RAB5B RAD9A RIN3 RP11-382A20.2 RP11-669E14.6 RP11-73O6.3 SAPS3 SMPD2 SNAI3-AS1 WNT4 ZSCAN2
Leg fat-free mass (left)	5.38	60	49	108.9	0.89	9.9e-25	AC083843.1 AOC1 AP3B1 BOK C6orf106 CD79B CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERI1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PNKD PPA2 PSMC5 QSOX2 RAB5B RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZNF500 ZNF76
Trunk fat percentage	3.25	36	24	53.3	0.04	8.2e-01	ABHD12 AC103965.1 ACP2 ADCY3 AP3B1 ARFGEF2 ARL17A C1QTNF4 C6orf106 CENPW CTD-3076O17.1 CTNNB1 DARS EEF1G EFEMP1 GOLGA6L4 GOLGA6L5 HTR4 LRRC37A2 MAPK13 NOB1 NSFP1 OTUD4 PSMC3 PSMC5 RAD9A RIN3 RP11-196G11.2 RP11-669E14.6 RP11-78I14.1 SYNM TPD52L2 WNT3 ZBTB38 ZNF500 ZSCAN2
Hand grip strength (right)	4.09	36	20	44.4	0.96	4.6e-21	ADCY3 ANGPTL1 AOC1 ARFGEF2 C1QTNF4 C6orf106 CD79B CRIPAK CYB561 DARS DCAF16 GDF5 H1FX JAG1 LOXL1-AS1 LRRC37A LRRC37A2 NOB1 NOSTRIN PCGF2 PSMC3 PSMC5 RAD9A RP11-250B2.6 RP11-669E14.6 RP11-73O6.3 SCMH1 SLC22A4 SMARCD2 TP53INP2 TRA2A TULP4 WNT3 ZBTB38 ZCCHC24 ZNF76
Current tobacco smoking	1.37	3	0	0.0	0.76	2.4e-01	C1QTNF4 FAM66A TPD52L2
Fed-up feelings	1.75	5	4	8.9	-0.99	1.8e-03	ARHGAP1 LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Relative age voice broke	1.85	5	4	8.9	-0.99	2.0e-03	LRRC37A LRRC37A2 RP11-669E14.6 SCMH1 WNT3
Taking other prescription medications	1.28	2	0	0.0	0.00	1.0e+00	ADAM19 AHI1
Age when periods started (menarche)	1.92	7	4	8.9	-0.01	9.9e-01	ADCY3 C1QTNF4 CENPW NFAT5 NOB1 RP11-669E14.6 SCMH1
Bilateral oophorectomy (both ovaries removed)	1.04	1	1	2.2	0.00	1.0e+00	WNT4
Heel bone mineral density (BMD) T-score, automated (left)	2.58	14	10	22.2	-0.27	2.9e-01	ACP2 ARHGAP1 CRIPAK DLEU2 EBPL ERI1 FAM66A FHL3 HHIP-AS1 IGHMBP2 JAG1 SAPS3 WNT4 ZNF438
High blood pressure	1.84	14	6	13.3	-0.86	4.8e-05	ACP2 ADO ARFGEF2 ARHGAP1 C1GALT1 DCAF16 ERI1 FAM66A HTR4 RP11-196G11.2 RP11-538P18.2 SLC22A4 TSPY26P U91328.21
Hayfever, allergic rhinitis or eczema	1.40	5	4	8.9	-0.67	1.5e-01	AHI1 C6orf106 RAB5B SLC22A4 ZBTB38
Medication: Levothyroxine sodium	1.38	2	1	2.2	0.00	1.0e+00	ERI1 RAB5B
Sitting height	8.54	98	86	191.1	0.90	1.6e-43	ABHD12 AC073834.3 AC083843.1 AC103965.1 ACP2 ADCY3 AOC1 AP3B1 ARFGEF2 ARHGAP1 ARL17A ASPSCR1 BOK C1QTNF4 C6orf106 CACFD1 CD79B CDKN2C CDO1 CENPW CEP120 COQ10A CRIPAK CTC-542B22.2 CTD-3076O17.1 CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 ERCC6L2 FAM136A FAM26F FHL3 GDF5 GOLGA6L4 GOLGA6L5 GSDMC GSK3A H1FX H6PD HHIP-AS1 ICAM2 IGHMBP2 JAG1 KIAA1614 LOC147727 LOXL1-AS1 LRRC37A LRRC37A2 MRPL42 MST1P2 MXD3 NFAT5 NOB1 NOC3L NOSTRIN OTUD4 PAN2 PCDHB5 PNKD PPA2 PSMC3 PSMC5 QSOX2 RAD9A RP11-250B2.6 RP11-538P18.2 RP11-669E14.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SERPINF1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TMED6 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT3 WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76 ZSCAN2
Chronic bronchitis/emphysema (father)	1.85	1	1	2.2	0.00	1.0e+00	PSMA4
Body mass index (BMI)	2.27	25	11	24.4	-0.52	4.0e-03	ACP2 ADCY3 AP3B1 ARFGEF2 C1QTNF4 C6orf106 CCDC87 CEP120 CTC-542B22.2 DARS DCAF16 ERI1 FAM66A HTR4 IGHMBP2 LOXL1-AS1 MST1P2 NFAT5 NOB1 OTUD4 PSMC3 RAB5B RP11-196G11.2 TMED6 TRIM38
Impedance of leg (left)	2.88	36	23	51.1	0.10	5.5e-01	AC103965.1 ADCY3 AOC1 AP3B1 C1QTNF4 C5orf34 CD79B CDO1 CEP120 CTD-3076O17.1 CTSS ERI1 FAM66A GDF5 GOLGA6L4 GOLGA6L5 H1FX IGHMBP2 LOXL1-AS1 LRRC37A2 MST1P2 OTUD4 PPA2 PSMC5 RAB24 RAB5B RAD9A RIN3 RP11-382A20.2 RP11-669E14.6 RP11-73O6.3 SAPS3 SMPD2 WNT3 WNT4 ZSCAN2
Leg predicted mass (left)	5.37	60	49	108.9	0.89	4.3e-25	AC083843.1 AOC1 AP3B1 BOK C6orf106 CD79B CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERI1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PLEKHM1P PNKD PPA2 PSMC5 RAB5B RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZNF500 ZNF76
Trunk fat mass	3.39	38	26	57.8	0.35	2.0e-02	ABHD12 AC103965.1 ACP2 ADCY3 AP3B1 ARL17A BOK C1QTNF4 C6orf106 CEP120 CTD-3076O17.1 CTNNB1 DLEU2 EEF1G EFEMP1 GDF5 GOLGA6L4 GOLGA6L5 H1FX HTR4 LRRC37A2 MAPK13 NOB1 NSFP1 OTUD4 PSMC3 RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 SYNM TP53INP2 TPD52L2 TRIM38 WNT3 ZBTB38 ZNF500 ZSCAN2
Waist circumference	2.27	21	15	33.3	0.07	7.2e-01	ABHD12 ACP2 ADCY3 AP3B1 C1QTNF4 C6orf106 CEP120 CTNNB1 GOLGA6L4 HTR4 NOB1 OTUD4 PSMC3 RAD9A RP11-196G11.2 RP11-78I14.1 RPL10A TPD52L2 ZBTB38 ZNF500 ZSCAN2
Number of incorrect matches in round	1.53	1	0	0.0	0.00	1.0e+00	RP11-196G11.2
Past tobacco smoking	1.55	4	0	0.0	-0.50	5.0e-01	C4orf14 CNPY2 NOB1 RP11-977G19.11
Nervous feelings	1.99	10	5	11.1	-0.50	1.4e-01	ARL17A CENPW ERI1 FAM66A FBXO38 LRRC37A LRRC37A2 RP11-196G11.2 RP11-669E14.6 WNT3
Frequency of tenseness / restlessness in last 2 weeks	1.65	4	3	6.7	-1.00	6.6e-04	LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Hearing difficulty/problems with background noise	1.41	1	0	0.0	0.00	1.0e+00	RP11-669E14.6
Hair/balding pattern: Pattern 2	2.03	5	3	6.7	-0.99	9.3e-04	C10orf11 LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Had menopause	1.06	1	0	0.0	0.00	1.0e+00	RP11-73O6.3
Had other major operations	1.61	1	0	0.0	0.00	1.0e+00	PPA2
Forced vital capacity (FVC)	11.84	144	121	268.9	0.98	6.0e-110	ABHD12 AC073834.3 AC083843.1 AC103965.1 ACP2 ADCY3 AHI1 ANGPTL1 AOC1 AP3B1 ARFGEF2 ARHGAP1 ARL17A ASPSCR1 BOK BTBD1 C10orf11 C1QTNF4 C4orf14 C6orf106 C6orf126 CACFD1 CCDC87 CD79B CDC123 CDKN2C CDO1 CENPW CEP120 CLUAP1 CNPY2 COQ10A CRIPAK CTA-85E5.10 CTB-36H16.2 CTC-542B22.2 CTD-3076O17.1 CTNNB1 CTSS CYB561 DARS DCAF16 DHDDS DIRAS3 DLEU2 DNAJC9-AS1 EBPL EEF1G EFEMP1 ERCC6L2 FAM136A FAM26F FER FHL3 GALNT12 GDF5 GOLGA6L5 GSDMC GSK3A GSTCD H1FX H6PD HHIP-AS1 HTR4 ICAM2 IGHMBP2 IPO8 JAG1 KIAA1614 LOC147727 LONRF2 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAPK13 MDM4 MICAL3 MRPL42 MST1P2 MXD3 NFAT5 NOB1 NOSTRIN NSFP1 NUDT5 OTUD4 PAN2 PCDHB5 PLEKHM1P PNKD PPA2 PPIAL4C PSMA4 PSMC3 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RNF123 RP11-196G11.2 RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-669E14.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SEC24C SERPINF1 SLMAP SMARCD2 SMPD2 SNAI3-AS1 TCP11L1 TMED6 TP53INP2 TPD52L2 TRA2A TRIM38 TRIM63 TSEN15 TSPY26P TULP4 U91328.21 UBXN2A WHAMM WNT3 WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF438 ZNF500 ZNF76 ZSCAN2
Heel bone mineral density (BMD) T-score, automated (right)	2.59	15	9	20.0	-0.22	3.8e-01	ACP2 ARHGAP1 C4orf14 CRIPAK DLEU2 EBPL ERI1 FAM66A FHL3 HHIP-AS1 IGHMBP2 SAPS3 WNT4 ZBTB38 ZNF438
Ever unenthusiastic/disinterested for a whole week	1.34	3	0	0.0	0.00	1.0e+00	LRRC37A LRRC37A2 WNT3
Qualifications: None of the above	1.48	3	1	2.2	0.00	1.0e+00	PPA2 RAB5B RNF123
Mouth/teeth dental problems	1.04	1	0	0.0	0.00	1.0e+00	WNT3
Allergy	1.68	8	4	8.9	0.80	9.0e-03	AHI1 C6orf106 CNPY2 RAB5B SEC24C SLC22A4 TPD52L2 ZBTB38
Diabetes (self-reported)	1.72	2	0	0.0	0.00	1.0e+00	C1GALT1 CLUAP1
Fluid intelligence score	1.94	5	1	2.2	0.80	1.7e-02	C1QTNF4 DCAF16 PPA2 RNF123 U91328.21
Neuroticism score	2.28	9	7	15.6	-0.38	3.1e-01	C1QTNF4 ERI1 FAM66A FBXO38 LRRC37A LRRC37A2 RP11-196G11.2 RP11-669E14.6 WNT3
Weight	4.23	58	38	84.4	0.76	4.7e-14	ABHD12 AC103965.1 AP3B1 BOK C1QTNF4 C6orf106 CD79B CDKN2C CENPW CEP120 CRIPAK CTD-3076O17.1 CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERI1 FAM66A GDF5 GIPC2 GOLGA6L4 GOLGA6L5 H1FX HHIP-AS1 HTR4 IGHMBP2 LOC147727 MRPL42 MXD3 OTUD4 PPA2 PSMC5 RAB24 RAB5B RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 RPL10A SAPS3 SCMH1 SERPINF1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TPD52L2 TRA2A TRIM38 TRIM63 TSEN15 WNT4 ZBTB38 ZCCHC24 ZNF500 ZNF76 ZSCAN2
Impedance of arm (right)	2.58	33	28	62.2	0.16	3.5e-01	AC083843.1 AC103965.1 AOC1 ARL17A C5orf34 CD79B CENPW CEP120 CTD-3076O17.1 EEF1G EFEMP1 ERI1 FAM66A FER GOLGA6L4 GOLGA6L5 H6PD IGHMBP2 LOXL1-AS1 LRRC37A2 MRPL42 MST1P2 NSFP1 PSMC5 RAB5B RIN3 RP11-669E14.6 RP11-73O6.3 RPL10A SAPS3 SCMH1 WNT3 ZSCAN2
Arm fat percentage (right)	2.84	27	13	28.9	-0.64	1.1e-04	ABHD12 ACP2 ADCY3 AP3B1 ARFGEF2 ARL17A C1QTNF4 C6orf106 CCDC87 CD79B CENPW DCAF16 EEF1G ERI1 FAM66A HTR4 MAPK13 NFAT5 NOB1 NSFP1 PSMC3 PSMC5 RP11-196G11.2 RP11-78I14.1 SYNM TPD52L2 ZNF76
Trunk fat-free mass	7.34	78	65	144.4	0.92	4.1e-39	AC083843.1 ACP2 ADCY3 AOC1 AP3B1 ARFGEF2 BOK C1QTNF4 C6orf106 C6orf126 CD79B CDKN2C CENPW CEP120 CNPY2 COQ10A CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM136A FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 ICAM2 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MST1P2 MXD3 NOSTRIN OTUD4 PAN2 PLEKHM1P PNKD PPA2 PSMC3 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Hip circumference	3.52	40	29	64.4	0.45	1.6e-03	AC103965.1 ACP2 ADCY3 AP3B1 BOK C1QTNF4 C6orf106 CD79B CDKN2C CEP120 CTNNB1 DLEU2 EBPL EFEMP1 ERI1 FAM66A GDF5 GIPC2 GOLGA6L4 H1FX HHIP-AS1 HTR4 LOC147727 NOB1 OTUD4 PSMC3 RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 RPL10A SCMH1 SMPD2 TP53INP2 TPD52L2 TRIM38 WNT4 ZBTB38 ZNF500 ZSCAN2
Time employed in main current job	1.32	3	1	2.2	0.00	1.0e+00	LRRC37A2 RP11-669E14.6 WNT3
Father's age at death	1.46	3	1	2.2	0.00	1.0e+00	BTBD1 ERI1 PSMA4
Worrier / anxious feelings	1.90	6	5	11.1	-0.17	7.5e-01	ERI1 FAM66A LRRC37A2 RP11-196G11.2 RP11-669E14.6 WNT3
Frequency of tiredness / lethargy in last 2 weeks	1.42	1	0	0.0	0.00	1.0e+00	CCDC87
Hair/balding pattern: Pattern 3	2.59	5	5	11.1	0.74	1.5e-01	CENPW LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Number of live births	1.26	4	1	2.2	-0.98	2.0e-02	LRRC37A LRRC37A2 WNT3 WNT4
Forced expiratory volume in 1-second (FEV1)	13.05	166	142	315.6	1.00	2.3e-196	ABHD12 AC073834.3 AC083843.1 AC103965.1 ACP2 ADAM19 ADCY3 ADO AHI1 ANGPTL1 AOC1 AP3B1 ARFGEF2 ARHGAP1 ARL17A ASPSCR1 BOK BTBD1 C10orf11 C1GALT1 C1QTNF4 C4orf14 C5orf34 C6orf106 C6orf126 CACFD1 CARS2 CCDC87 CD79B CDC123 CDKN2C CDO1 CENPW CEP120 CLUAP1 CNPY2 COQ10A CRIPAK CTA-85E5.10 CTB-36H16.2 CTC-542B22.2 CTD-3076O17.1 CTNNB1 CTSS CYB561 DARS DCAF16 DENND2D DHDDS DIRAS3 DLEU2 DNAJC9-AS1 DNALI1 EBPL EEF1G EFEMP1 ERCC6L2 ERI1 FAM136A FAM168A FAM26F FAM66A FBXO38 FER FHL3 GALNT12 GDF5 GIPC2 GM2A GOLGA6L4 GOLGA6L5 GSDMC GSK3A GSTCD H1FX H6PD HESX1 HHIP-AS1 HTR4 ICAM2 IGHMBP2 IPO8 JAG1 KIAA1614 LOC147727 LONRF2 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAPK13 MDM4 METAP2 MICAL3 MRPL42 MST1P2 MXD3 NFAT5 NOB1 NOC3L NOSTRIN NSFP1 NUDT5 OTUD4 PCDHB5 PCGF2 PLEKHM1P PNKD PPA2 PPIAL4C PSMA4 PSMC3 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RNF123 RP11-196G11.2 RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-669E14.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE2 SCUBE3 SEC24C SERPINF1 SLC22A4 SLMAP SMARCD2 SMPD2 SNAI3-AS1 SOGA2 SYNM TCP11L1 THSD4 TMED6 TP53INP2 TPD52L2 TRA2A TRIM38 TRIM63 TSEN15 TSPY26P TULP4 U91328.21 UBXN2A WHAMM WNT3 WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF438 ZNF500 ZNF76 ZSCAN2
Pulse rate	1.31	4	2	4.4	-0.06	9.4e-01	CEP120 CTNNB1 EEF1G ZBTB38
Qualifications: A levels/AS levels or equivalent	1.33	2	0	0.0	0.00	1.0e+00	GDF5 RNF123
Mouth/teeth dental problems: Dentures	1.22	3	0	0.0	0.00	1.0e+00	ERI1 PSMA4 TRIM38
Asthma	2.53	11	7	15.6	-0.94	1.5e-06	ADAM19 AHI1 CNPY2 HTR4 RAB5B SCUBE3 SLC22A4 TPD52L2 TRIM38 U91328.21 ZNF76
Medication: Ibuprofen (e.g. Nurofen)	1.26	1	0	0.0	0.00	1.0e+00	U91328.21
Medication: Cholesterol lowering	1.28	2	0	0.0	0.00	1.0e+00	LOC147727 RP11-196G11.2
Lung cancer (father)	1.52	1	1	2.2	0.00	1.0e+00	PSMA4
Impedance of arm (left)	2.53	32	26	57.8	0.26	1.2e-01	AC103965.1 AOC1 ARL17A CD79B CENPW CEP120 CTD-3076O17.1 EEF1G EFEMP1 ERI1 FAM66A FER GOLGA6L4 GOLGA6L5 H6PD IGHMBP2 LOXL1-AS1 LRRC37A LRRC37A2 MRPL42 MST1P2 NSFP1 PSMC5 RAB5B RIN3 RP11-669E14.6 RP11-73O6.3 SAPS3 SCMH1 TSPY26P WNT3 ZSCAN2
Arm fat mass (right)	2.54	24	15	33.3	-0.13	5.1e-01	ABHD12 ACP2 ADCY3 AP3B1 C1QTNF4 C6orf106 CCDC87 CEP120 CTNNB1 ERI1 FAM66A HTR4 NOB1 OTUD4 PSMC3 RAB5B RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 TP53INP2 TPD52L2 TRIM38 ZBTB38 ZNF500
Trunk predicted mass	7.34	78	65	144.4	0.92	4.2e-39	AC083843.1 ACP2 ADCY3 AOC1 AP3B1 ARFGEF2 BOK C1QTNF4 C6orf106 C6orf126 CD79B CDKN2C CENPW CEP120 CNPY2 COQ10A CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM136A FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 ICAM2 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MST1P2 MXD3 NOSTRIN OTUD4 PAN2 PLEKHM1P PNKD PPA2 PSMC3 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Standing height	9.96	113	103	228.9	0.91	1.8e-51	AC083843.1 AC103965.1 ACP2 ADCY3 ADO AOC1 AP3B1 ARFGEF2 ARHGAP1 ARL17A ASPSCR1 BOK C1QTNF4 C4orf14 C6orf106 C6orf126 CACFD1 CCDC87 CD79B CDKN2C CDO1 CENPW CEP120 CNPY2 COQ10A CRIPAK CTC-542B22.2 CTD-3076O17.1 CTNNB1 CYB561 DCAF16 DHDDS DLEU2 DNALI1 EBPL EFEMP1 ERCC6L2 ERI1 FAM136A FAM26F FAM66A FER FHL3 GDF5 GIPC2 GOLGA6L4 GOLGA6L5 GSDMC GSK3A H1FX H6PD HHIP-AS1 ICAM2 IGHMBP2 IPO8 JAG1 KIAA1614 LOC147727 LOXL1-AS1 LRRC37A2 MRPL42 MST1P2 MXD3 NFAT5 NOB1 NOC3L NOSTRIN NSFP1 OTUD4 PAN2 PCDHB5 PLEKHM1P PNKD PPA2 PPIAL4C PSMC3 PSMC5 QSOX2 RAB24 RAD9A RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-669E14.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TMED6 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 U91328.21 UBXN2A WNT3 WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76 ZSCAN2
Tense / 'highly strung'	1.48	3	2	4.4	0.00	1.0e+00	ERI1 FAM66A RP11-196G11.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.56	2	0	0.0	0.00	1.0e+00	CCDC87 U91328.21
Hair/balding pattern: Pattern 4	4.16	10	9	20.0	0.35	3.2e-01	C10orf11 CENPW CTB-36H16.2 CTNNB1 FAM136A LRRC37A LRRC37A2 RP11-669E14.6 WNT3 ZBTB38
Birth weight of first child	2.96	14	7	15.6	0.95	5.7e-08	ARFGEF2 ASPSCR1 C6orf126 DCAF16 IPO8 MAPK13 NOC3L OTUD4 PPA2 RP11-78I14.1 RPL10A WNT4 ZBTB38 ZNF76
Peak expiratory flow (PEF)	7.24	58	33	73.3	0.97	4.2e-39	ADAM19 ARFGEF2 ARL17A ASPSCR1 BOK BTBD1 C10orf11 C1GALT1 C4orf14 C6orf106 CACFD1 CCDC87 CD79B CDC123 CDKN2C CTA-85E5.10 DCAF16 DHDDS DLEU2 DNALI1 EBPL EFEMP1 ERI1 FAM168A FAM66A FBXO38 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 HTR4 LOC147727 LOXL1-AS1 LRRC37A LRRC37A2 MDM4 METAP2 NOSTRIN NUDT5 OTUD4 PCGF2 PNKD PPA2 PSMC5 RAD9A RNF123 RP11-669E14.6 RPL10A SAPS3 SMPD2 THSD4 TP53INP2 TRIM63 UBXN2A WNT3 ZHX2 ZNF76
Blood clot in the leg (DVT)	1.43	1	1	2.2	0.00	1.0e+00	CACFD1
Medication: Paracetamol	1.84	5	5	11.1	-0.70	1.9e-01	LRRC37A LRRC37A2 RP11-669E14.6 U91328.21 WNT3
Headache pain in last month	1.92	6	5	11.1	-0.60	2.1e-01	LRRC37A LRRC37A2 RAB5B RP11-669E14.6 U91328.21 WNT3
Medication for cholesterol, blood pressure or diabetes	1.39	1	0	0.0	0.00	1.0e+00	TSPY26P
Gout (self-reported)	1.17	1	0	0.0	0.00	1.0e+00	U91328.21
Hypothyroidism/myxoedema (self-reported)	1.56	5	4	8.9	0.11	8.6e-01	AHI1 ERI1 FAM66A RAB5B ZNF76
Medication: Ventolin 100micrograms inhaler	1.67	1	0	0.0	0.00	1.0e+00	RAB5B
Birth weight	2.62	13	3	6.7	0.80	5.3e-04	C1QTNF4 C6orf126 CENPW CEP120 DCAF16 MAPK13 PPA2 RP11-73O6.3 TRA2A TULP4 UBXN2A WNT4 ZNF76
Chronic bronchitis/emphysema (mother)	1.69	2	1	2.2	0.00	1.0e+00	HHIP-AS1 PSMA4
High blood pressure (siblings)	1.49	1	0	0.0	0.00	1.0e+00	RP11-196G11.2
Forced vital capacity (FVC), Best measure	12.44	149	124	275.6	0.98	2.0e-115	ABHD12 AC073834.3 AC083843.1 AC103965.1 ACP2 ADCY3 ADO AHI1 ANGPTL1 AOC1 AP3B1 ARFGEF2 ARHGAP1 ARL17A ASPSCR1 BOK BTBD1 C10orf11 C1GALT1 C1QTNF4 C4orf14 C5orf34 C6orf106 C6orf126 CACFD1 CARS2 CCDC87 CD79B CDC123 CDKN2C CDO1 CENPW CEP120 CLUAP1 CNPY2 COQ10A CRIPAK CTA-85E5.10 CTB-36H16.2 CTC-542B22.2 CTD-3076O17.1 CTNNB1 CTSS CYB561 DARS DCAF16 DHDDS DIRAS3 DLEU2 DNAJC9-AS1 DNALI1 EBPL EEF1G EFEMP1 ERCC6L2 FAM136A FAM26F FER FHL3 GALNT12 GDF5 GOLGA6L5 GSDMC GSK3A GSTCD H1FX H6PD HHIP-AS1 HTR4 ICAM2 IGHMBP2 IPO8 JAG1 KIAA1614 LOC147727 LONRF2 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAPK13 MDM4 MICAL3 MRPL42 MST1P2 MXD3 NFAT5 NOB1 NOC3L NOSTRIN NSFP1 NUDT5 OTUD4 PAN2 PCDHB5 PLEKHM1P PNKD PPA2 PPIAL4C PSMA4 PSMC3 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RNF123 RP11-196G11.2 RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-669E14.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE2 SCUBE3 SEC24C SERPINF1 SMARCD2 SMPD2 SNAI3-AS1 TCP11L1 TMED6 TP53INP2 TPD52L2 TRA2A TRIM38 TRIM63 TSEN15 TULP4 U91328.21 UBXN2A WHAMM WNT3 WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF438 ZNF500 ZNF76 ZSCAN2
Body fat percentage	3.10	33	20	44.4	-0.37	2.0e-02	ABHD12 AC073834.3 AC103965.1 ACP2 ADCY3 AP3B1 ARFGEF2 C1QTNF4 C6orf106 CD79B CENPW CTD-3076O17.1 DARS DCAF16 EEF1G ERI1 GOLGA6L4 GOLGA6L5 GSK3A HTR4 MAPK13 NOB1 PSMC3 PSMC5 RIN3 RP11-196G11.2 RP11-78I14.1 SYNM TPD52L2 TRIM38 ZBTB38 ZNF500 ZSCAN2
Leg fat percentage (right)	2.97	29	17	37.8	-0.70	3.0e-06	ABHD12 AC073834.3 ACP2 ADCY3 ARFGEF2 C1QTNF4 C6orf106 CD79B CENPW DARS DCAF16 ERI1 GDF5 GOLGA6L4 GSK3A HTR4 MAPK13 NOB1 PLEKHM1P PSMC3 PSMC5 RIN3 RP11-196G11.2 SMARCD2 SNAI3-AS1 SYNM TPD52L2 TRIM38 ZSCAN2
Arm fat-free mass (right)	6.13	66	54	120.0	0.91	1.6e-30	AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C1QTNF4 C6orf106 CD79B CDKN2C CENPW CEP120 CNPY2 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PAN2 PNKD PPA2 PSMC5 RAB24 RAB5B RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Comparative body size at age 10	2.66	13	7	15.6	-0.53	3.4e-02	ACP2 ADCY3 AP3B1 ARL17A C1QTNF4 ERI1 FAM66A GOLGA6L4 NSFP1 PSMC3 RP11-196G11.2 SAPS3 U91328.21
Worry too long after embarrassment	1.75	6	0	0.0	0.05	9.2e-01	AHI1 ERI1 FAM66A PPA2 RP11-669E14.6 WNT3
Wheeze or whistling in the chest in last year	2.07	3	0	0.0	0.00	1.0e+00	ADAM19 CTC-542B22.2 TPD52L2
Health satisfaction	1.25	1	0	0.0	0.00	1.0e+00	CCDC87
Qualifications: College or University degree	1.62	11	7	15.6	0.76	4.1e-03	EEF1G GDF5 LRRC37A LRRC37A2 MDM4 PPA2 RAB5B RNF123 RP11-669E14.6 SMARCD2 WNT3
Medication for pain relief, constipation, heartburn	1.71	5	4	8.9	0.56	3.3e-01	LRRC37A LRRC37A2 RP11-669E14.6 U91328.21 WNT3
Medication: Blood pressure	1.59	2	1	2.2	0.00	1.0e+00	ERI1 TSPY26P
Medication: Seretide 50 evohaler	1.57	1	0	0.0	0.00	1.0e+00	SLC22A4
Mean time to correctly identify matches	1.73	3	2	4.4	0.00	1.0e+00	ARL17A NSFP1 SCUBE2
Whole body fat mass	2.97	32	25	55.6	0.21	2.0e-01	ABHD12 AC103965.1 ACP2 ADCY3 AP3B1 C1QTNF4 C6orf106 CEP120 CTD-3076O17.1 CTNNB1 EFEMP1 ERI1 GDF5 GOLGA6L4 GOLGA6L5 H1FX HTR4 MAPK13 NOB1 OTUD4 PSMC3 RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 SYNM TP53INP2 TPD52L2 TRIM38 ZBTB38 ZNF500 ZSCAN2
Leg fat mass (right)	2.56	27	14	31.1	-0.03	8.7e-01	ABHD12 ACP2 ADCY3 AP3B1 C1QTNF4 C6orf106 CTNNB1 DARS ERI1 FAM66A GIPC2 GOLGA6L4 GOLGA6L5 HTR4 NOB1 OTUD4 PSMC3 RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 SYNM TPD52L2 TRIM38 ZBTB38 ZNF500 ZSCAN2
Arm predicted mass (right)	6.07	66	52	115.6	0.91	1.8e-29	AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C1QTNF4 C6orf106 CD79B CDKN2C CENPW CEP120 CNPY2 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PNKD PPA2 PSMC5 RAB24 RAB5B RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 UBXN2A WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Pulse rate, automated reading	1.65	12	6	13.3	-0.52	5.4e-02	AC103965.1 BTBD1 C6orf106 CEP120 CTNNB1 DARS EEF1G PCGF2 RAB5B RP11-382A20.2 TRIM63 ZBTB38
Alcohol intake frequency.	1.77	9	8	17.8	-0.97	1.4e-06	C1QTNF4 LRRC37A LRRC37A2 PPA2 PSMC3 RP11-669E14.6 TMED6 UBXN2A WNT3
Comparative height size at age 10	8.38	85	67	148.9	0.90	8.0e-38	AC103965.1 ACP2 ADCY3 AOC1 AP3B1 ARFGEF2 ARHGAP1 ARL17A ASPSCR1 BOK C1QTNF4 C6orf106 CD79B CDKN2C CDO1 CENPW CEP120 CRIPAK CTD-3076O17.1 CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM136A FAM26F FER FHL3 GDF5 GOLGA6L4 GOLGA6L5 GSDMC H1FX H6PD HHIP-AS1 ICAM2 IPO8 KIAA1614 LOC147727 LOXL1-AS1 LRRC37A2 MICAL3 MRPL42 MST1P2 MXD3 NSFP1 OTUD4 PLEKHM1P PNKD PPA2 PPIAL4C PSMC3 PSMC5 QSOX2 RAB24 RAD9A RP11-250B2.6 RP11-669E14.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 U91328.21 UBXN2A WNT3 WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76 ZSCAN2
Suffer from 'nerves'	1.81	2	1	2.2	0.99	1.0e-02	C1QTNF4 FAM66A
Overall health rating	1.58	6	2	4.4	-0.69	1.3e-01	C6orf106 CCDC87 DCAF16 ERI1 HTR4 RP11-196G11.2
Leg pain on walking	1.25	1	0	0.0	0.00	1.0e+00	WNT3
Knee pain experienced in last month	1.71	3	2	4.4	0.00	1.0e+00	GDF5 LOC147727 RP11-196G11.2
Hypertension (Self-reported)	1.81	14	6	13.3	-0.86	3.6e-05	ACP2 ADO ARFGEF2 ARHGAP1 C1GALT1 DCAF16 ERI1 FAM66A HTR4 RP11-196G11.2 RP11-538P18.2 SLC22A4 TSPY26P U91328.21
Forced expiratory volume in 1-second (FEV1), predicted	7.65	48	33	73.3	0.97	2.5e-37	AC103965.1 ACP2 ADCY3 BOK C1QTNF4 C6orf106 CD79B CDKN2C CENPW CNPY2 CTD-3076O17.1 DCAF16 DLEU2 EBPL EFEMP1 FER GDF5 GOLGA6L4 GOLGA6L5 GSDMC H1FX HHIP-AS1 LOC147727 MRPL42 MST1P2 NOSTRIN OTUD4 PAN2 PSMC3 PSMC5 RAB24 RAD9A RP11-690I21.1 RP11-73O6.3 RP11-977G19.11 RPL10A SCMH1 SCUBE3 SLC22A4 SMARCD2 TP53INP2 TRA2A TSEN15 ZBTB38 ZHX2 ZNF500 ZNF76 ZSCAN2
Whole body fat-free mass	6.56	72	60	133.3	0.92	3.4e-35	AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C1QTNF4 C6orf106 CD79B CDKN2C CENPW CEP120 CNPY2 COQ10A CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PAN2 PLEKHM1P PNKD PPA2 PSMC3 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Leg fat-free mass (right)	5.39	61	49	108.9	0.90	4.0e-27	AC083843.1 AOC1 AP3B1 BOK C6orf106 CD79B CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERI1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PLEKHM1P PNKD PPA2 PSMC5 QSOX2 RAB5B RAD9A RIN3 RP11-250B2.6 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZNF500 ZNF76
Arm fat percentage (left)	2.94	25	14	31.1	-0.69	3.6e-05	ABHD12 ACP2 ADCY3 AP3B1 ARFGEF2 C1QTNF4 C6orf106 CCDC87 CD79B CENPW DCAF16 ERI1 FAM66A HTR4 MAPK13 NFAT5 NOB1 PSMC3 PSMC5 RP11-196G11.2 RP11-78I14.1 SYNM TPD52L2 TRIM38 ZNF76
Handedness (chirality/laterality): Left-handed	1.70	5	3	6.7	0.97	4.9e-03	ARL17A LRRC37A2 NSFP1 RP11-669E14.6 WNT3
Mood swings	1.86	5	5	11.1	-0.99	1.0e-03	FBXO38 LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Loneliness, isolation	1.52	3	1	2.2	0.66	2.2e-01	C1QTNF4 LRRC37A2 WNT3
Long-standing illness, disability or infirmity	1.31	1	0	0.0	0.00	1.0e+00	NOB1
Diabetes diagnosed by doctor	1.80	3	0	0.0	0.00	1.0e+00	C1GALT1 CENPW NOB1
Mouth/teeth dental problems: Mouth ulcers	1.68	5	5	11.1	-0.78	1.2e-01	CTSS LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Mineral and other dietary supplements	1.29	1	0	0.0	0.00	1.0e+00	NFAT5
Asthma (self-reported)	2.48	10	7	15.6	-0.94	5.5e-06	ADAM19 AHI1 CNPY2 HTR4 RAB5B SCUBE3 SLC22A4 TRIM38 U91328.21 ZNF76
Osteoporosis (self-reported)	1.52	1	1	2.2	0.00	1.0e+00	SAPS3
Osteoarthritis (self-reported)	1.26	1	0	0.0	0.00	1.0e+00	LOC147727
Smoking status: Current	1.44	1	0	0.0	0.00	1.0e+00	C1QTNF4
Forced expiratory volume in 1-second (FEV1), predicted percentage	7.02	54	31	68.9	0.98	7.8e-39	ABHD12 AC073834.3 ADAM19 ANGPTL1 ASPSCR1 BOK BTBD1 C10orf11 CDC123 CEP120 CLUAP1 CTA-85E5.10 CTSS DHDDS EEF1G ERI1 FAM168A FAM66A FBXO38 GSTCD HHIP-AS1 HTR4 JAG1 LRRC37A LRRC37A2 MICAL3 NOB1 NUDT5 PCGF2 PPA2 PSMA4 QSOX2 RIN3 RNF123 RP11-196G11.2 RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-669E14.6 RP11-967K21.1 RPL10A SEC24C SLMAP SMPD2 SOGA2 THSD4 TPD52L2 TRIM38 TRIM63 U91328.21 WHAMM WNT3 WNT4 ZNF76
Whole body water mass	6.53	72	61	135.6	0.92	3.2e-35	AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C1QTNF4 C6orf106 CD79B CDKN2C CENPW CEP120 CNPY2 COQ10A CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PAN2 PLEKHM1P PNKD PPA2 PSMC3 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Leg predicted mass (right)	5.40	62	49	108.9	0.90	1.9e-27	AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C6orf106 CD79B CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERI1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PLEKHM1P PNKD PPA2 PSMC5 QSOX2 RAB5B RAD9A RIN3 RP11-250B2.6 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZNF500 ZNF76
Arm fat mass (left)	2.57	27	16	35.6	-0.03	8.6e-01	ABHD12 ACP2 ADCY3 AP3B1 C1QTNF4 C6orf106 CCDC87 CEP120 CTNNB1 ERI1 FAM66A GDF5 GOLGA6L4 HTR4 NOB1 OTUD4 PSMC3 RAB5B RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 TP53INP2 TPD52L2 TRIM38 ZBTB38 ZNF500
Number of self-reported non-cancer illnesses	1.59	2	0	0.0	0.00	1.0e+00	CCDC87 SLC22A4
Average weekly champagne plus white wine intake	1.34	4	0	0.0	0.99	1.0e-02	LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Miserableness	1.60	6	5	11.1	-0.56	2.5e-01	ERI1 FAM66A LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Guilty feelings	1.72	6	0	0.0	-0.76	7.9e-02	CNPY2 LRRC37A LRRC37A2 RP11-669E14.6 UBXN2A WNT3
Medication: Blood pressure	1.72	5	2	4.4	0.05	9.3e-01	C1GALT1 ERI1 FAM66A LRRC37A2 RP11-669E14.6
Supplements: Fish oil (including cod liver oil)	1.43	2	0	0.0	0.00	1.0e+00	CCDC87 NFAT5
High cholesterol (Self-reported)	1.37	3	0	0.0	0.00	1.0e+00	FAM136A LOC147727 RP11-196G11.2
Medication: Bendroflumethiazide	1.49	2	0	0.0	0.00	1.0e+00	ERI1 FAM66A
Medication: Paracetamol	1.73	5	4	8.9	-0.78	1.2e-01	LRRC37A LRRC37A2 RP11-669E14.6 U91328.21 WNT3
Ever smoked	1.47	2	0	0.0	0.00	1.0e+00	C4orf14 PSMA4
Basal metabolic rate	6.00	69	53	117.8	0.90	4.0e-31	AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C6orf106 CD79B CDKN2C CENPW CEP120 CNPY2 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PAN2 PNKD PPA2 PSMC5 QSOX2 RAB24 RAB5B RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76 ZSCAN2
Leg fat percentage (left)	2.97	31	17	37.8	-0.69	2.7e-06	ABHD12 AC073834.3 ACP2 ADCY3 ARFGEF2 C1QTNF4 C6orf106 CD79B CENPW DARS DCAF16 ERI1 GDF5 GIPC2 GOLGA6L4 GSK3A HTR4 MAPK13 NOB1 PLEKHM1P PSMC3 PSMC5 RIN3 RP11-196G11.2 SMARCD2 SYNM TPD52L2 TRIM38 UBXN2A ZNF76 ZSCAN2
Arm fat-free mass (left)	5.94	66	51	113.3	0.90	1.8e-29	AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C1QTNF4 C6orf106 CD79B CDKN2C CENPW CEP120 CNPY2 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PAN2 PNKD PPA2 PSMC5 RAB24 RAB5B RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Number of operations (self-reported)	1.69	1	1	2.2	0.00	1.0e+00	PPA2
Average weekly beer plus cider intake	1.61	1	0	0.0	0.00	1.0e+00	RNF123
Irritability	1.76	7	5	11.1	-0.33	4.6e-01	ERI1 FAM66A LRRC37A LRRC37A2 RP11-196G11.2 RP11-669E14.6 WNT3
Ever had prostate specific antigen (PSA) test	1.41	1	0	0.0	0.00	1.0e+00	ZBTB38
Fractured/broken bones in last 5 years	1.49	2	0	0.0	0.00	1.0e+00	CRIPAK WNT3
Diastolic blood pressure, automated reading	2.09	16	11	24.4	-0.17	5.2e-01	ADO BTBD1 CEP120 CTNNB1 DARS DCAF16 ERI1 FAM66A JAG1 MICAL3 RP11-538P18.2 SCMH1 SLMAP THSD4 U91328.21 ZNF76
Myopia	1.95	2	1	2.2	0.00	1.0e+00	ACP2 QSOX2
Vascular/heart problems diagnosed by doctor	1.73	12	7	15.6	0.85	2.2e-04	ACP2 ADO ARHGAP1 C1GALT1 DCAF16 ERI1 FAM66A NFAT5 RP11-196G11.2 RP11-538P18.2 SLC22A4 TSPY26P
Cholesterol lowering medication	1.48	1	0	0.0	0.00	1.0e+00	RP11-196G11.2
Pain experienced in last month	1.54	3	0	0.0	0.00	1.0e+00	CENPW RP11-196G11.2 RP11-669E14.6
Deep venous thrombosis (DVT) (self-reported)	1.37	1	1	2.2	0.00	1.0e+00	CACFD1
Heart disease (siblings)	1.29	1	0	0.0	0.00	1.0e+00	TP53INP2
Pack years of smoking	2.44	2	1	2.2	0.00	1.0e+00	CYB561 PSMA4
Impedance of whole body	2.78	39	27	60.0	0.13	4.3e-01	AC083843.1 AC103965.1 ADCY3 AOC1 C5orf34 CD79B CENPW CEP120 CTD-3076O17.1 EEF1G EFEMP1 ERI1 FAM66A GDF5 GOLGA6L4 GOLGA6L5 H6PD IGHMBP2 LOXL1-AS1 LRRC37A LRRC37A2 MRPL42 MST1P2 NSFP1 OTUD4 PPA2 PSMC5 RAB24 RAB5B RAD9A RIN3 RP11-382A20.2 RP11-669E14.6 RP11-73O6.3 SAPS3 SCMH1 SMPD2 WNT3 ZSCAN2
Leg fat mass (left)	2.51	27	15	33.3	-0.03	8.5e-01	ABHD12 ACP2 ADCY3 AP3B1 C1QTNF4 C6orf106 DARS ERI1 FAM66A GIPC2 GOLGA6L4 GOLGA6L5 HTR4 NOB1 OTUD4 PSMC3 RAB5B RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 SYNM TPD52L2 TRIM38 ZBTB38 ZNF500 ZSCAN2
Arm predicted mass (left)	5.87	65	50	111.1	0.90	2.1e-28	AC083843.1 AOC1 AP3B1 ARFGEF2 BOK C6orf106 CD79B CDKN2C CENPW CEP120 CNPY2 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 FAM66A FHL3 GDF5 GIPC2 GSDMC H1FX HHIP-AS1 IGHMBP2 IPO8 KIAA1614 LOC147727 MRPL42 MXD3 NOSTRIN OTUD4 PAN2 PNKD PPA2 PSMC5 RAB24 RAB5B RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RPL10A SAPS3 SCMH1 SCUBE3 SERPINF1 SLC22A4 SMARCD2 SMPD2 TP53INP2 TRA2A TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76

Associations by panel

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Adipose Subcutaneous	50	1.43	3.3
GTEx	Adipose Visceral Omentum	32	1.57	3.5
GTEx	Adrenal Gland	13	0.89	3.1
GTEx	Artery Aorta	38	1.28	3.5
GTEx	Artery Coronary	20	1.69	3.8
GTEx	Artery Tibial	43	1.14	3.3
GTEx	Brain Caudate basal ganglia	10	1.09	3.3
GTEx	Brain Cerebellar Hemisphere	20	1.34	3.5
GTEx	Brain Cerebellum	23	1.16	3.4
GTEx	Brain Cortex	23	2.22	3.7
GTEx	Brain Frontal Cortex BA9	13	1.41	3.6
GTEx	Brain Hippocampus	9	1.72	3.6
GTEx	Brain Hypothalamus	14	2.37	3.9
GTEx	Brain Nucleus accumbens basal ganglia	14	1.62	3.8
GTEx	Brain Putamen basal ganglia	6	0.96	3.3
GTEx	Breast Mammary Tissue	28	1.42	3.6
GTEx	Breast Mammary Tissue (Male)	26	2.18	3.9
GTEx	Breast Mammary Tissue (Female)	25	1.52	3.4
GTEx	Cells EBV-transformed lymphocytes	28	1.97	3.7
GTEx	Cells Transformed fibroblasts	54	1.29	3.3
GTEx	Colon Sigmoid	23	1.57	3.6
GTEx	Colon Transverse	28	1.36	3.4
GTEx	Esophagus Gastroesophageal Junction	27	1.87	3.6
GTEx	Esophagus Mucosa	47	1.42	3.4
GTEx	Esophagus Muscularis	49	1.52	3.5
GTEx	Heart Atrial Appendage	27	1.71	3.7
GTEx	Heart Left Ventricle	21	1.37	3.5
GTEx	Liver	13	1.81	3.5
GTEx	Lung	44	1.53	3.4
GTEx	Muscle Skeletal	33	1.14	3.3
GTEx	Nerve Tibial	66	1.53	3.3
GTEx	Ovary	18	1.98	4.2
GTEx	Pancreas	26	1.59	3.4
GTEx	Pituitary	25	2.24	3.7
GTEx	Prostate	12	1.44	3.5
GTEx	Skin Not Sun Exposed Suprapubic	42	1.71	3.4
GTEx	Skin Sun Exposed Lower leg	52	1.43	3.5
GTEx	Small Intestine Terminal Ileum	9	1.95	4.0
GTEx	Spleen	20	1.42	3.5
GTEx	Stomach	23	1.58	3.6
GTEx	Testis	40	1.27	3.5
GTEx	Thyroid	54	1.35	3.3
GTEx	Uterus	9	1.59	4.1
GTEx	Vagina	9	1.42	3.5
GTEx	Whole Blood	33	1.66	3.2
METSIM	Adipose	31	0.67	2.8
NTR	Blood	19	0.79	2.8
ROSMAP	Brain Pre-frontal Cortex	34	0.77	2.9
YFS	Blood	41	0.89	2.8
CommonMind	Brain Pre-frontal Cortex	45	0.84	2.8
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	17	1.03	3.0
The Cancer Genome Atlas	Breast Invasive Carcinoma	48	1.09	2.8
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	14	1.28	3.3
The Cancer Genome Atlas	Colon Adenocarcinoma	15	0.73	2.9
The Cancer Genome Atlas	Esophageal Carcinoma	10	1.46	3.3
The Cancer Genome Atlas	Glioblastoma Multiforme	18	1.76	3.3
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	30	1.10	3.0
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	49	1.20	2.9
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	15	0.73	2.8
The Cancer Genome Atlas	Brain Lower Grade Glioma	47	1.09	2.9
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	11	0.99	3.0
The Cancer Genome Atlas	Lung Adenocarcinoma	43	1.46	3.1
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	29	1.16	2.9
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	21	1.32	3.0
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	13	0.78	3.0
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	21	1.58	3.3
The Cancer Genome Atlas	Prostate Adenocarcinoma	55	1.19	2.9
The Cancer Genome Atlas	Rectum Adenocarcinoma	12	1.74	3.2
The Cancer Genome Atlas	Soft Tissue Sarcoma	15	1.40	3.1
The Cancer Genome Atlas	Skin Cutaneous Melanoma	7	1.31	3.3
The Cancer Genome Atlas	Stomach Adenocarcinoma	17	1.01	2.9
The Cancer Genome Atlas	Testicular Germ Cell Tumors	9	0.70	2.9
The Cancer Genome Atlas	Thyroid Carcinoma	47	0.91	2.9
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	8	1.57	3.3