Best TWAS P=8.95e-10 · Best GWAS P=9.87e-09 conditioned to 0.0125
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pancreas | C1GALT1 | 0.44 | 0.11 | enet | 24 | 0.22 | 8.8e-10 | -4.3 | -5.3 | 1.1e-07 | -0.39 | 0.63 | 0.34 | FALSE |
| 2 | GTEx | Spleen | C1GALT1 | 0.56 | 0.29 | lasso | 6 | 0.46 | 3.2e-13 | -3.7 | -5.8 | 7.9e-09 | -0.64 | 0.07 | 0.91 | FALSE |
| 3 | GTEx | Stomach | C1GALT1 | 0.24 | 0.07 | enet | 17 | 0.12 | 1.9e-06 | -3.7 | -5.2 | 1.7e-07 | -0.45 | 0.67 | 0.26 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | C1GALT1 | 0.24 | 0.13 | lasso | 5 | 0.23 | 4.6e-29 | 4.3 | -5.8 | 5.6e-09 | -0.63 | 0.59 | 0.39 | FALSE |
| 5 | YFS | Blood | C1GALT1 | 0.35 | 0.20 | enet | 45 | 0.32 | 4.3e-109 | -4.6 | -6.1 | 9.0e-10 | -0.61 | 0.35 | 0.64 | TRUE |
| 6 | The Cancer Genome Atlas | Lung Adenocarcinoma | C1GALT1 | 0.08 | 0.03 | blup | 112 | 0.06 | 2.5e-07 | 5.7 | -5.9 | 3.8e-09 | -0.66 | 0.00 | 1.00 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | C1GALT1 | 0.04 | 0.00 | blup | 108 | 0.02 | 2.7e-03 | 2.3 | -5.8 | 8.2e-09 | -0.70 | 0.01 | 0.87 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C1GALT1 | 0.12 | 0.05 | enet | 10 | 0.13 | 9.9e-14 | -4.1 | -5.4 | 7.0e-08 | -0.59 | 0.68 | 0.30 | FALSE |