Best TWAS P=3.43e-08 · Best GWAS P=1.37e-07 conditioned to 0.597
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | NOC3L | 0.11 | 0.10 | lasso | 7 | 0.10 | 1.7e-06 | -4.6 | -5.1 | 2.7e-07 | 0.91 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Nerve Tibial | NOC3L | 0.17 | 0.20 | lasso | 5 | 0.20 | 6.0e-14 | -5.3 | -5.3 | 1.2e-07 | 0.99 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | NOC3L | 0.32 | 0.21 | enet | 31 | 0.23 | 8.2e-13 | -4.9 | -5.5 | 3.4e-08 | 0.92 | 0.02 | 0.98 | TRUE |
| 4 | METSIM | Adipose | NOC3L | 0.10 | 0.10 | lasso | 7 | 0.11 | 3.3e-16 | -5.2 | -5.3 | 1.1e-07 | 0.94 | 0.01 | 0.98 | FALSE |