Best TWAS P=3.31e-18 · Best GWAS P=8.11e-27 conditioned to 5.79e-13
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | LOXL1-AS1 | 0.12 | 0.11 | enet | 19 | 0.12 | 2.4e-09 | -7.74 | 5.7 | 1.0e-08 | -0.49 | 0.98 | 0.01 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | LOXL1-AS1 | 0.28 | 0.09 | lasso | 6 | 0.17 | 1.7e-12 | 3.78 | 6.9 | 5.8e-12 | -0.64 | 1.00 | 0.00 | TRUE |
| 3 | GTEx | Esophagus Mucosa | LOXL1-AS1 | 0.30 | 0.03 | enet | 37 | 0.05 | 2.0e-04 | 0.81 | 5.5 | 4.3e-08 | -0.37 | 0.18 | 0.07 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | LOXL1-AS1 | 0.11 | 0.05 | enet | 11 | 0.10 | 7.3e-09 | 2.12 | 7.0 | 2.6e-12 | -0.41 | 0.82 | 0.08 | FALSE |
| 5 | GTEx | Testis | LOXL1-AS1 | 0.36 | 0.15 | lasso | 10 | 0.13 | 2.4e-06 | -7.74 | -8.0 | 1.5e-15 | 0.58 | 0.51 | 0.07 | FALSE |
| 6 | GTEx | Thyroid | LOXL1-AS1 | 0.15 | 0.03 | enet | 40 | 0.03 | 2.6e-03 | -7.74 | 8.7 | 3.3e-18 | -0.33 | 0.12 | 0.21 | TRUE |