Hub : Traits :

Forced vital capacity (FVC), Best measure

2691 significantly associated models · 553 unique genes.

Significant Loci

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	1	9049032	9576675	1	1	7.3e-09	1.9e-07	3.3e-05	36	H6PD
2	1	16142960	18132937	15	8	3.2e-34	3.2e-34	1.0e+00	100	ATP13A2 CROCC ESPNP MST1L MST1P2 RP11-108M9.5
3	1	22197336	22718991	1	1	2.0e-15	6.1e-13	6.7e-05	69	WNT4
4	1	25475418	27595862	12	12	8.6e-14	1.7e-13	NaN	NaN	CNKSR1 DHDDS PDIK1L RP1-125I3.2 RPS6KA1 SEPN1 SH3BGRL3 TRIM63
5	1	36079508	37494602	2	1	6.6e-08	3.3e-07	1.0e+00	100	RP11-268J15.5
6	1	37628741	39167106	4	1	4.2e-08	7.1e-08	2.3e-02	82	RP11-109P14.10
7	1	40748755	42542658	5	1	4.6e-29	2.0e-21	2.5e-01	99	SCMH1
8	1	67814420	69212053	1	1	6.6e-08	1.2e-06	3.0e-01	96	DIRAS3
9	1	149672809	152070472	18	7	3.1e-17	3.9e-17	NaN	NaN	CTSS HIST2H2AA3 HORMAD1 PSMB4 RP11-196G18.24 SETDB1
10	1	153241677	154638826	1	1	2.1e-07	1.9e-06	4.9e-04	46	RP11-422P24.10
11	1	171640888	173105511	1	1	6.1e-08	2.3e-15	5.5e-12	24	PIGC
12	1	178129899	179534540	1	1	5.0e-09	1.0e-09	5.1e-02	90	ANGPTL1
13	1	180186713	181614143	1	1	5.5e-11	1.1e-10	4.0e-01	98	KIAA1614
14	1	182744205	184739300	2	2	1.9e-09	1.1e-08	2.1e-04	58	SMG7 TSEN15
15	1	203692179	205241659	2	1	4.5e-11	6.1e-11	1.0e-02	85	MDM4
16	1	217760821	220479607	3	3	4.7e-12	1.7e-16	8.6e-11	38	RRP15 TGFB2 ZC3H11B
17	1	227222963	228614123	1	1	2.1e-10	7.5e-09	2.7e-03	73	JMJD4
18	2	23453834	25889403	8	3	9.8e-19	1.9e-17	5.6e-01	100	ADCY3 NCOA1 UBXN2A
19	2	35883253	37567226	5	1	1.3e-12	2.0e-11	5.6e-08	34	RP11-78I14.1
20	2	42030533	42531871	1	1	2.1e-07	2.3e-09	1.3e-03	71	PKDCC
21	2	46117914	47538477	1	1	1.6e-07	3.4e-10	4.3e-04	68	PIGF
22	2	47845523	49300234	1	1	1.4e-07	1.3e-06	1.5e-01	91	FOXN2
23	2	55401562	56843605	1	2	8.3e-47	4.6e-60	1.0e-07	89	EFEMP1
24	2	67709195	69180661	1	1	3.0e-07	3.7e-06	5.1e-01	98	PPP3R1
25	2	69786188	72356449	5	2	3.9e-11	1.4e-08	1.0e+00	100	FAM136A ZNF638
26	2	100029106	101419887	1	1	2.4e-07	1.4e-07	7.3e-04	59	AC092667.2
27	2	135898023	137435625	3	1	8.8e-11	3.1e-08	1.3e-02	80	DARS
28	3	8294862	8858201	1	1	1.0e-07	7.7e-09	2.1e-03	72	LMCD1
29	3	48702606	50448632	3	2	3.3e-08	6.0e-07	1.2e-02	74	GPX1 RNF123
30	3	52166147	53860103	3	1	3.3e-08	1.3e-06	4.8e-02	83	RFT1
31	3	70757099	71880670	1	1	1.8e-08	1.2e-09	1.0e+00	100	FOXP1
32	3	128334272	129714372	1	1	1.2e-09	5.8e-11	6.0e-04	72	H1FX
33	4	644410	2058475	2	1	5.4e-09	8.7e-07	2.0e-01	93	CRIPAK
34	4	2811841	4219590	2	3	3.9e-11	1.3e-09	1.0e+00	100	LRPAP1 RGS12
35	4	17104059	18507692	2	7	3.5e-47	1.8e-42	NaN	NaN	DCAF16 NCAPG
36	4	57080198	58531645	3	1	1.8e-08	1.5e-08	1.0e+00	100	C4orf14
37	4	100238413	100791805	1	1	1.5e-08	5.9e-07	9.8e-01	100	MTTP
38	4	105373669	107622327	5	2	3.0e-18	2.5e-21	7.5e-03	92	INTS12 PPA2
39	4	144882744	146788825	3	2	4.1e-26	6.2e-27	9.8e-03	94	ANAPC10 OTUD4
40	5	64196669	65022213	1	1	7.2e-09	3.2e-11	1.0e-03	76	ADAMTS6
41	5	77052232	78753539	2	1	2.5e-17	1.1e-20	5.6e-05	81	AP3B1
42	5	107390303	109224099	1	1	2.3e-10	5.5e-13	6.6e-05	69	FER
43	5	114443019	115851911	1	1	2.1e-09	2.9e-08	6.2e-01	99	CDO1
44	5	121480516	123002130	2	2	4.4e-11	1.4e-13	4.3e-03	85	CEP120 CTB-36H16.2
45	5	126587995	128220643	4	8	4.1e-09	5.9e-08	1.0e+00	100	CTC-228N24.3 FBN2 FLJ33630 SLC12A2
46	5	133240927	134784086	2	3	2.2e-10	1.4e-08	3.7e-04	61	CAMLG SAR1B
47	5	139323257	141214127	13	1	1.8e-09	1.1e-07	3.5e-01	97	PCDHB5
48	5	176040488	177260129	3	1	3.1e-14	1.3e-11	3.0e-04	72	RAB24
49	6	25285943	26689223	1	2	1.1e-09	5.7e-11	9.8e-04	75	U91328.21
50	6	33686103	36804187	14	3	1.3e-20	2.6e-31	2.2e-31	0	C6orf126 PACSIN1 ZNF76
51	6	75327919	76901651	1	1	1.8e-07	2.4e-06	9.6e-01	100	FILIP1
52	6	80120201	81763771	2	1	3.7e-12	3.1e-12	1.0e+00	100	RP11-250B2.6
53	6	108994161	110844259	9	1	1.4e-11	1.1e-11	1.0e+00	100	RP11-425D10.10
54	6	115877511	117481404	3	1	4.3e-10	1.6e-09	1.8e-01	95	RP1-93H18.7
55	6	125970401	127355237	1	1	4.8e-32	1.9e-34	6.4e-04	92	CENPW
56	6	129638583	132080991	4	2	4.2e-24	7.1e-26	5.2e-14	49	L3MBTL3 LOC285733
57	6	134905567	136516257	2	1	2.5e-09	5.0e-08	2.3e-01	95	AHI1
58	6	141924760	143855272	2	1	1.6e-23	2.0e-25	1.0e+00	100	GPR126
59	6	158041511	159632250	1	1	4.8e-12	6.8e-10	1.0e-03	72	TULP4
60	7	2032803	3581391	2	1	7.0e-12	1.4e-11	1.0e+00	100	GNA12
61	7	22946782	24382726	3	2	2.5e-13	4.0e-18	4.7e-04	84	CCDC126 TRA2A
62	7	91539717	93160671	1	1	1.2e-11	3.2e-11	1.6e-02	87	CDK6
63	7	139727135	141316834	2	1	3.4e-10	4.0e-10	1.0e+00	100	BRAF
64	7	149847287	151252618	1	1	1.5e-08	5.3e-10	7.4e-04	70	AOC1
65	8	56269387	57683880	2	1	1.3e-14	9.6e-24	8.8e-11	58	RPS20
66	8	119737284	121136001	1	1	1.6e-09	7.5e-11	1.1e-09	12	NOV
67	8	123101743	124679448	1	1	2.8e-09	1.3e-09	3.4e-02	88	ZHX2
68	8	130517157	131045893	1	1	9.6e-21	3.3e-20	5.5e-05	81	GSDMC
69	8	135106207	136500554	1	1	8.9e-09	1.4e-13	6.4e-11	22	AC083843.1
70	9	14857740	16758776	1	1	1.6e-10	7.7e-11	9.2e-02	93	CCDC171
71	9	96326127	100114913	11	7	2.2e-18	5.8e-23	1.2e-02	94	C9orf3 ERCC6L2 HABP4 PTCH1 RP11-435O5.4 ZNF169
72	9	135629944	137034272	1	1	2.1e-08	4.6e-11	1.7e-04	67	CACFD1
73	9	138403706	139836362	1	1	1.2e-24	8.5e-22	4.4e-01	99	QSOX2
74	10	11515875	12989666	2	1	3.8e-09	7.2e-10	1.0e-03	72	CDC123
75	10	21087485	22724472	2	1	4.0e-08	2.2e-08	1.3e-01	93	CASC10
76	10	30435876	32016090	1	1	1.6e-08	1.1e-08	4.9e-02	88	ZNF438
77	10	60712592	62185494	1	1	7.2e-08	1.2e-08	1.3e-08	1	SLC16A9
78	10	76664253	80383574	3	2	2.3e-08	1.2e-10	2.5e-04	68	C10orf11 DLG5
79	10	80443273	81901722	1	2	2.6e-11	1.1e-07	8.6e-02	90	ZCCHC24
80	10	103527782	104934709	1	1	4.2e-08	1.3e-05	8.6e-02	84	TMEM180
81	10	123438113	124889817	1	1	1.3e-08	1.2e-18	8.4e-14	28	PLEKHA1
82	11	46010847	48783497	22	9	3.9e-15	3.5e-13	NaN	NaN	ACP2 C11orf49 C1QTNF4 DDB2 MTCH2 PSMC3 ZNF408
83	11	61627881	63078986	4	1	2.6e-09	7.5e-09	1.0e+00	100	ROM1
84	11	64663227	69476279	18	13	6.2e-37	4.4e-34	1.0e+00	100	CCDC87 CTD-3074O7.12 CTSF KCNK7 MRGPRF PELI3 RAD9A SF3B2 ZDHHC24
85	11	88816538	89548892	1	1	7.7e-08	1.9e-09	3.8e-03	77	NOX4
86	11	116467589	117216213	1	1	2.5e-07	2.9e-08	3.8e-02	86	SIK3
87	12	27616589	29042392	1	1	1.9e-14	2.5e-12	6.6e-01	100	RP11-967K21.1
88	12	30084002	31526510	1	1	2.4e-08	9.3e-09	1.0e+00	100	IPO8
89	12	55633142	57684978	12	1	5.5e-12	1.9e-10	9.8e-01	100	RP11-977G19.11
90	12	64519806	66337026	2	1	3.9e-11	1.8e-17	4.0e-12	34	LEMD3
91	12	93165619	94589220	1	1	9.9e-12	3.0e-24	3.2e-15	40	MRPL42
92	12	101575652	103101412	3	2	9.5e-10	7.3e-10	5.4e-02	90	CCDC53 DRAM1
93	13	49557805	51390447	3	2	6.1e-18	6.6e-17	1.0e+00	100	DLEU2 EBPL
94	13	114302502	115106996	1	1	1.3e-07	4.8e-07	1.0e+00	100	CDC16
95	14	36900126	37890433	1	1	5.7e-08	3.1e-09	4.2e-03	77	SLC25A21
96	14	92286262	93847625	1	1	2.4e-13	4.2e-14	1.0e+00	100	RIN3
97	15	39530508	41012695	1	1	6.9e-09	1.9e-07	1.5e-05	31	EIF2AK4
98	15	50649361	52091785	1	1	2.1e-07	5.6e-10	5.9e-04	69	TNFAIP8L3
99	15	66797492	68245488	1	1	2.3e-07	2.1e-09	6.5e-04	68	AAGAB
100	15	71418503	73087366	2	1	1.3e-10	4.2e-10	1.6e-05	52	MYO9A
101	15	73524629	74915888	1	2	3.3e-18	8.1e-27	5.8e-13	55	LOXL1-AS1
102	15	74942759	78022087	8	2	3.3e-11	2.4e-09	1.0e+00	100	MAN2C1 TSPAN3
103	15	78135979	79537269	3	1	4.7e-08	5.4e-09	4.0e-02	88	PSMA4
104	15	83167559	85883064	12	14	7.9e-13	1.2e-20	NaN	NaN	AC103965.1 CSPG4P11 GOLGA6L5 RP11-182J1.14 RP11-182J1.16 RP11-382A20.2 SCAND2P UBE2Q2P1 WHAMM
105	15	89171135	89674383	1	1	3.3e-09	8.2e-14	1.1e-07	50	HAPLN3
106	15	99816860	101209341	1	1	1.4e-10	2.6e-13	1.6e-10	24	CTD-3076O17.1
107	16	86671	1488646	1	1	2.3e-07	6.2e-08	1.0e-09	-27	NARFL
108	16	2741812	5510848	11	2	6.5e-16	6.8e-16	2.7e-04	80	CLUAP1 ZNF500
109	16	8016708	9438692	1	1	2.6e-08	8.3e-09	1.5e-04	57	METTL22
110	16	13697975	14759768	1	1	9.7e-08	5.6e-08	2.6e-03	69	RP11-65J21.3
111	16	30347731	31833122	15	9	4.0e-14	1.5e-12	1.0e+00	100	HSD3B7 KAT8 MIR4519 MYST1 RP11-196G11.2 SETD1A STX1B
112	16	68523336	71093625	14	3	9.1e-17	1.8e-25	1.3e-01	98	NFAT5 NOB1 TMED6
113	16	80779331	82901701	2	6	2.0e-08	5.6e-08	1.0e+00	100	CMIP MPHOSPH6
114	16	88030355	90172696	3	2	1.1e-07	1.3e-06	4.6e-03	66	CHMP1A SNAI3-AS1
115	17	923916	2420934	3	1	2.1e-09	2.7e-08	8.1e-01	100	SERPINF1
116	17	27207120	28629763	3	1	8.6e-09	5.8e-08	3.4e-01	97	ANKRD13B
117	17	36244358	37644854	1	1	1.0e-08	3.4e-07	1.8e-01	93	PIP4K2B
118	17	41946180	46899254	33	9	1.5e-38	5.9e-31	1.0e+00	100	ADAM11 ARL17A LRRC37A LRRC37A2 NSFP1 PLCD3 RP11-669E14.6 RP5-890E16.2 WNT3
119	17	60821100	64251733	21	9	1.2e-29	2.5e-25	1.0e+00	100	AXIN2 CCDC47 CD79B CYB561 ICAM2 PLEKHM1P PSMC5 SMARCD2
120	17	78665405	80866427	11	3	1.3e-16	2.1e-14	4.4e-01	99	ASPSCR1 DCXR RP11-1055B8.4
121	18	69836	907710	1	1	1.3e-07	5.8e-06	7.0e-05	23	USP14
122	18	59159599	60668346	1	1	1.4e-08	1.8e-04	2.0e-04	2	KIAA1468
123	19	741758	1238899	1	1	8.7e-08	7.6e-08	1.0e+00	100	WDR18
124	19	3309021	4732167	1	1	1.0e-07	9.0e-09	3.3e-03	74	PIAS4
125	19	8367158	8848856	1	1	2.8e-09	6.5e-17	9.5e-12	34	MYO1F
126	19	10068513	11459260	2	1	6.8e-10	2.2e-10	1.0e+00	100	LOC147727
127	19	40403029	43237764	5	2	2.2e-13	2.3e-13	1.0e+00	100	GSK3A SHKBP1
128	19	45585167	46981943	2	1	1.2e-07	9.1e-09	6.3e-03	77	RSPH6A
129	20	9925555	11347455	1	1	3.9e-09	1.9e-08	9.7e-03	79	JAG1
130	20	31382860	34737037	13	3	2.2e-13	1.2e-12	3.8e-01	98	E2F1 GDF5 TP53INP2
131	20	43723627	45205482	3	1	3.2e-08	2.9e-08	1.8e-01	94	SNX21
132	20	46551079	48603940	9	1	1.9e-19	1.0e-22	1.0e+00	100	ARFGEF2
133	20	61561153	62912463	10	1	1.3e-12	1.8e-12	1.0e+00	100	LIME1
134	21	17199289	18230733	1	1	1.4e-07	1.1e-07	1.0e+00	100	C21orf34
135	21	35795370	36339264	1	1	1.6e-07	9.7e-09	8.0e-03	79	CLIC6
136	22	30034994	30820707	2	1	7.5e-10	3.4e-10	1.4e-01	94	HORMAD2
137	22	42563308	44107669	1	1	9.3e-08	1.1e-05	8.1e-01	100	PACSIN2

Pleiotropic Associations

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr	corr P	genes
Bipolar Disorder (2018)	1.68	3	0	0.0	-0.99	1.3e-02	AC103965.1 LOC147727 RP11-182J1.14
Bipolar Disorder or Schizophrenia	2.01	14	9	20.0	-0.67	1.1e-03	AC103965.1 BRAF CTD-3074O7.12 CTSF CTSS GOLGA6L5 PACSIN1 PACSIN2 PCDHB5 PSMA4 RP11-182J1.14 RP11-182J1.16 U91328.21 UBE2Q2P1
Depressed Affect (Nagel 2018)	2.28	13	7	15.6	-0.42	1.3e-01	C11orf49 C1QTNF4 GPX1 HORMAD2 LRRC37A LRRC37A2 MTCH2 MYST1 PTCH1 RP11-669E14.6 STX1B WNT3 ZNF408
Depression (Nagel 2018)	1.44	1	0	0.0	0.00	1.0e+00	WNT3
Intelligence (Savage-Jansen 2018)	1.95	20	16	35.6	0.82	4.9e-07	ACP2 ARFGEF2 ARL17A C1QTNF4 CENPW DCAF16 FOXP1 GPX1 HABP4 MTCH2 NCAPG NSFP1 PCDHB5 PPA2 PTCH1 RNF123 TULP4 UBXN2A WNT3 ZNF638
Neuroticism (Nagel 2018)	2.38	20	13	28.9	-0.32	1.4e-01	ARL17A C11orf49 C1QTNF4 CENPW GPX1 HORMAD2 HSD3B7 KAT8 LRRC37A LRRC37A2 MYST1 NSFP1 PTCH1 RP11-196G11.2 RP11-669E14.6 SETD1A STX1B U91328.21 WNT3 ZNF408
Schizophrenia (2018)	1.71	9	4	8.9	-0.63	1.7e-02	AC103965.1 CTSS GOLGA6L5 PCDHB5 PSMA4 RP11-182J1.14 RP11-182J1.16 U91328.21 UBE2Q2P1
Worry (Nagel 2018)	1.96	15	10	22.2	-0.13	5.9e-01	ARL17A C1QTNF4 CENPW HORMAD2 HSD3B7 KAT8 LRRC37A LRRC37A2 MTCH2 MYST1 PTCH1 RP11-669E14.6 SETD1A STX1B WNT3
Alzheimer’s Disease (including proxy)	1.75	6	2	4.4	-0.52	2.9e-01	HSD3B7 KAT8 MYST1 RSPH6A SETD1A STX1B
Crohns Disease (2017)	1.22	6	3	6.7	-0.09	8.7e-01	ADCY3 GPX1 HORMAD2 LIME1 RFT1 RP11-268J15.5
Irritable Bowel Disease (IBD)	1.41	8	3	6.7	-0.52	1.9e-01	ADCY3 CTSS GPX1 HORMAD1 HORMAD2 LIME1 NCOA1 SETDB1
Ulcerative Colitis (UC)	1.45	4	3	6.7	-0.09	9.1e-01	GNA12 GPX1 LIME1 RNF123
Reaction Time	1.59	6	3	6.7	-0.54	2.6e-01	ARL17A C11orf49 NSFP1 PIAS4 TMEM180 ZNF638
Verbal and Numeric Reasoning (VNR)	2.02	15	11	24.4	0.74	5.0e-04	ARFGEF2 C1QTNF4 CENPW DCAF16 FOXP1 GPX1 HABP4 MTCH2 NCAPG PPA2 RNF123 TULP4 U91328.21 UBXN2A ZNF638
Breast Cancer	1.61	12	10	22.2	-0.48	8.3e-02	ADCY3 CASC10 CTC-228N24.3 FLJ33630 HIST2H2AA3 L3MBTL3 LRRC37A LRRC37A2 RIN3 RP11-196G18.24 RP11-669E14.6 WNT3
Ovarian Cancer	1.69	5	5	11.1	0.96	9.1e-03	CASC10 LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Prostate Cancer	1.46	4	1	2.2	-0.45	5.5e-01	GPX1 LIME1 MDM4 TMEM180
Age at First Birth	1.13	1	1	2.2	0.00	1.0e+00	GPX1
Body Mass Index (BMI) (2010)	1.49	3	2	4.4	-0.94	1.9e-02	ADCY3 C1QTNF4 MTCH2
Coronary Artery Disease (CAD)	1.32	1	0	0.0	0.00	1.0e+00	DCAF16
Crohns Disease (2012)	1.22	2	1	2.2	0.00	1.0e+00	HORMAD2 LIME1
Fasting Glucose	1.23	2	1	2.2	0.00	1.0e+00	ACP2 DDB2
HDL Cholesterol	2.03	7	7	15.6	0.82	1.4e-02	ACP2 C11orf49 C1QTNF4 DDB2 MTCH2 MYO1F ZNF408
LDL Cholesterol	1.34	2	1	2.2	0.00	1.0e+00	CACFD1 LOC147727
Lupus	1.11	1	0	0.0	0.00	1.0e+00	ZNF76
Neuroticism (2016)	1.60	5	2	4.4	-0.73	1.6e-01	C1QTNF4 GPX1 LRRC37A2 RP11-669E14.6 WNT3
Primary Biliary Cirrhosis	1.34	3	0	0.0	0.00	1.0e+00	LRRC37A RP11-669E14.6 WNT3
Schizophrenia (2014)	1.61	6	3	6.7	-0.55	1.6e-01	AC103965.1 CTSS FOXN2 GOLGA6L5 RP11-182J1.14 RP11-182J1.16
Triglycerides	1.65	5	2	4.4	0.48	4.1e-01	KAT8 MYST1 RGS12 SETD1A SIK3
Ulcerative Colitis	1.51	3	2	4.4	0.00	1.0e+00	GNA12 GPX1 LIME1
Blood Eosinophil Count	1.26	38	22	48.9	0.04	8.2e-01	AAGAB AHI1 ARL17A C4orf14 CACFD1 CDK6 CTC-228N24.3 CTSS DLEU2 FAM136A FLJ33630 GNA12 GPX1 GSK3A HORMAD1 KAT8 L3MBTL3 LRRC37A LRRC37A2 MRGPRF MYO1F NARFL NOB1 PACSIN1 PDIK1L PSMC3 RFT1 RIN3 RP11-182J1.16 RP11-425D10.10 RP11-669E14.6 SEPN1 SETD1A SETDB1 TRIM63 WNT3 ZNF169 ZNF76
Blood Platelet Count	1.35	46	39	86.7	-0.40	2.8e-03	ADAM11 ANKRD13B ARL17A C1QTNF4 C4orf14 CACFD1 CDK6 CEP120 CTSS DCAF16 DDB2 E2F1 FAM136A FER GNA12 HABP4 HORMAD1 KIAA1614 LIME1 LMCD1 LOC147727 LRRC37A LRRC37A2 MAN2C1 MIR4519 MTCH2 NARFL NCAPG NSFP1 OTUD4 PACSIN1 PACSIN2 PSMC3 RGS12 RIN3 RP11-182J1.16 RP11-425D10.10 RP11-669E14.6 SCMH1 SETDB1 SIK3 SMARCD2 TMEM180 TULP4 ZCCHC24 ZHX2
Blood Red Count	2.16	53	38	84.4	-0.11	4.1e-01	AC103965.1 ANKRD13B AOC1 ASPSCR1 ATP13A2 C21orf34 CACFD1 CCDC87 CD79B CENPW CHMP1A CTD-3074O7.12 CTSF DARS EIF2AK4 FAM136A GPR126 HSD3B7 KAT8 KCNK7 L3MBTL3 LIME1 LRRC37A LRRC37A2 MAN2C1 MIR4519 MST1L MST1P2 MYO9A MYST1 NFAT5 NOB1 NOV PELI3 PIAS4 PSMB4 PSMC5 RAB24 RAD9A RP11-182J1.16 RP11-196G11.2 RP11-669E14.6 RP11-977G19.11 RPS6KA1 SETD1A SHKBP1 SLC25A21 SNAI3-AS1 SNX21 STX1B TSPAN3 UBE2Q2P1 WNT3
Blood White Count	1.55	52	33	73.3	-0.68	2.5e-09	ACP2 AHI1 ANKRD13B C1QTNF4 C4orf14 CACFD1 CCDC126 CCDC47 CDK6 CENPW CEP120 CTB-36H16.2 CTC-228N24.3 DCAF16 DLG5 EBPL FER FLJ33630 GNA12 GPX1 GSK3A HABP4 HORMAD2 KIAA1614 L3MBTL3 LIME1 LRRC37A MAN2C1 MTCH2 NOB1 PACSIN1 PCDHB5 PSMC3 PTCH1 RFT1 RIN3 RP11-669E14.6 RP5-890E16.2 SCMH1 SETD1A SLC16A9 SMARCD2 STX1B TMEM180 TRA2A TSPAN3 TULP4 UBXN2A ZHX2 ZNF169 ZNF638 ZNF76
Heel T-Score	3.20	84	63	140.0	-0.17	9.9e-02	AAGAB AC103965.1 ACP2 ADAMTS6 ADCY3 ANAPC10 ANKRD13B ARL17A ASPSCR1 AXIN2 C11orf49 C4orf14 CACFD1 CCDC53 CDK6 CEP120 CHMP1A CRIPAK CSPG4P11 CTB-36H16.2 CTC-228N24.3 CTSS DCAF16 DCXR DDB2 DIRAS3 DLEU2 E2F1 EBPL FBN2 GNA12 GPR126 GSDMC H1FX HIST2H2AA3 HSD3B7 IPO8 JAG1 JMJD4 KAT8 KIAA1614 L3MBTL3 LIME1 LRRC37A LRRC37A2 MRGPRF MYST1 NCAPG NOV NSFP1 PIGC PIP4K2B PKDCC PLCD3 PLEKHM1P PTCH1 RFT1 ROM1 RP11-109P14.10 RP11-182J1.14 RP11-196G18.24 RP11-435O5.4 RP11-669E14.6 RP11-967K21.1 RP5-890E16.2 RPS20 SCMH1 SETD1A SLC16A9 SMARCD2 SNAI3-AS1 STX1B TGFB2 TNFAIP8L3 TULP4 UBE2Q2P1 WHAMM WNT3 WNT4 ZCCHC24 ZNF169 ZNF408 ZNF638 ZNF76
BMI	2.22	50	31	68.9	-0.67	6.5e-09	AAGAB AC092667.2 ACP2 ADCY3 ANKRD13B AP3B1 ARFGEF2 ATP13A2 C1QTNF4 CASC10 CCDC171 CCDC47 CEP120 CMIP CTSF DCAF16 DDB2 EIF2AK4 FOXP1 GPX1 GSDMC GSK3A HABP4 HSD3B7 KAT8 L3MBTL3 LOXL1-AS1 MST1L MST1P2 MTCH2 MYO9A MYST1 NFAT5 NOB1 OTUD4 PACSIN1 PIAS4 PIGF PSMB4 RFT1 RNF123 SAR1B SETD1A SLC16A9 SMARCD2 STX1B TMED6 TSPAN3 ZCCHC24 ZNF500
Height	10.41	202	195	433.3	0.92	1.3e-97	AAGAB AC083843.1 AC103965.1 ACP2 ADAM11 ADAMTS6 ADCY3 AHI1 ANAPC10 ANKRD13B AOC1 AP3B1 ARFGEF2 ARL17A ASPSCR1 ATP13A2 AXIN2 BRAF C10orf11 C11orf49 C1QTNF4 C4orf14 C6orf126 C9orf3 CACFD1 CAMLG CCDC126 CCDC47 CCDC53 CCDC87 CD79B CDC123 CDC16 CDK6 CDO1 CENPW CEP120 CHMP1A CLUAP1 CMIP CNKSR1 CRIPAK CROCC CSPG4P11 CTC-228N24.3 CTD-3074O7.12 CTD-3076O17.1 CTSF CTSS CYB561 DCAF16 DCXR DDB2 DHDDS DIRAS3 DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 ERCC6L2 ESPNP FAM136A FBN2 FER FILIP1 FLJ33630 GDF5 GNA12 GOLGA6L5 GPR126 GPX1 GSDMC GSK3A H1FX H6PD HABP4 HAPLN3 HIST2H2AA3 HORMAD2 ICAM2 IPO8 JAG1 JMJD4 KCNK7 KIAA1614 L3MBTL3 LEMD3 LIME1 LMCD1 LOC147727 LOC285733 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 MDM4 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTCH2 MTTP MYO1F MYO9A NARFL NCAPG NCOA1 NFAT5 NOB1 NOV NOX4 NSFP1 OTUD4 PACSIN1 PACSIN2 PCDHB5 PDIK1L PELI3 PIAS4 PIGC PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PPA2 PPP3R1 PSMB4 PSMC3 PSMC5 PTCH1 QSOX2 RAB24 RAD9A RFT1 RGS12 RP11-1055B8.4 RP11-108M9.5 RP11-109P14.10 RP11-182J1.14 RP11-182J1.16 RP11-196G18.24 RP11-250B2.6 RP1-125I3.2 RP11-268J15.5 RP11-382A20.2 RP11-425D10.10 RP11-435O5.4 RP11-65J21.3 RP11-669E14.6 RP11-78I14.1 RP11-977G19.11 RP1-93H18.7 RP5-890E16.2 RPS20 RPS6KA1 RRP15 SAR1B SCAND2P SCMH1 SEPN1 SERPINF1 SETDB1 SF3B2 SH3BGRL3 SHKBP1 SLC12A2 SLC16A9 SLC25A21 SMARCD2 SNAI3-AS1 SNX21 TGFB2 TMED6 TMEM180 TNFAIP8L3 TP53INP2 TRA2A TRIM63 TSEN15 TSPAN3 TULP4 UBE2Q2P1 UBXN2A USP14 WNT3 WNT4 ZC3H11B ZCCHC24 ZDHHC24 ZHX2 ZNF169 ZNF408 ZNF438 ZNF500 ZNF638 ZNF76
Waist Hip Ratio (WHR)	2.40	48	28	62.2	-0.28	3.9e-02	AAGAB AC103965.1 ADCY3 ANAPC10 AP3B1 ASPSCR1 ATP13A2 CCDC53 CD79B CENPW CLUAP1 CNKSR1 CROCC CTC-228N24.3 DCXR DLEU2 EBPL FLJ33630 GDF5 GOLGA6L5 GPX1 L3MBTL3 LOC147727 LRRC37A LRRC37A2 MST1L MST1P2 MYO1F NFAT5 NSFP1 OTUD4 PIP4K2B PSMC5 RAB24 RAD9A ROM1 RP11-108M9.5 RP11-182J1.14 RP11-182J1.16 RP1-125I3.2 RP11-669E14.6 SH3BGRL3 TNFAIP8L3 TRIM63 UBE2Q2P1 WNT3 WNT4 ZCCHC24
Systolic Blood Pressure	1.88	37	24	53.3	-0.53	2.8e-04	ACP2 ADAM11 ADCY3 ARFGEF2 ARL17A C11orf49 C1QTNF4 CCDC53 CDC123 CDC16 CDK6 CEP120 CTC-228N24.3 DCAF16 DDB2 EFEMP1 FER FLJ33630 GDF5 GPX1 JMJD4 LOC285733 LRRC37A2 NCAPG NOV NSFP1 PCDHB5 PLEKHM1P PPP3R1 RGS12 RIN3 RP11-1055B8.4 RP11-109P14.10 RP11-669E14.6 ZHX2 ZNF408 ZNF500
Smoking Status	1.38	8	2	4.4	-0.22	6.0e-01	CASC10 FOXP1 GPX1 MTCH2 NOB1 RFT1 TMEM180 WNT3
Allergy or Eczema	1.16	6	3	6.7	-0.54	2.7e-01	AAGAB AHI1 GNA12 LIME1 PACSIN1 TMEM180
Cardiovascular Disease	1.91	21	12	26.7	-0.85	2.5e-08	AAGAB ACP2 C11orf49 CDC16 CDK6 CHMP1A CTC-228N24.3 DCAF16 DDB2 FOXN2 HSD3B7 KAT8 MYST1 NCAPG PPP3R1 RGS12 RP11-1055B8.4 SETD1A SMARCD2 STX1B ZNF408
Hypothyroidism (self reported)	1.36	6	5	11.1	-0.01	9.9e-01	AHI1 HORMAD2 PLEKHA1 RGS12 RP11-109P14.10 SIK3
Respiratory disease	1.52	7	3	6.7	-0.65	1.1e-01	AAGAB AHI1 C4orf14 CTD-3074O7.12 LIME1 ZNF169 ZNF76
Type 2 Diabetes (T2D) (2018)	1.75	7	2	4.4	-0.50	2.5e-01	C1QTNF4 CENPW MAN2C1 NOB1 PDIK1L TRIM63 ZCCHC24
Lung FEV1/FVC ratio	4.47	55	40	88.9	-0.39	1.3e-03	AC103965.1 ADCY3 ANKRD13B ATP13A2 C10orf11 C4orf14 CASC10 CCDC171 CDC123 CENPW CEP120 CROCC CTC-228N24.3 DRAM1 EFEMP1 EIF2AK4 ESPNP FLJ33630 GDF5 GNA12 GOLGA6L5 GPR126 HIST2H2AA3 INTS12 LMCD1 LOXL1-AS1 LRRC37A LRRC37A2 MST1L MST1P2 MYO1F NCOA1 NOV OTUD4 PIP4K2B PLEKHA1 PLEKHM1P PPA2 PSMA4 PTCH1 RP11-108M9.5 RP11-182J1.14 RP11-182J1.16 RP11-268J15.5 RP11-382A20.2 RP5-890E16.2 RPS20 RRP15 SETD1A SHKBP1 STX1B TGFB2 TSPAN3 WHAMM ZNF76
Lung FVC	6.32	137	108	240.0	0.92	8.7e-64	AAGAB AC092667.2 ADAM11 AHI1 ANAPC10 ANGPTL1 AOC1 AP3B1 ARFGEF2 ARL17A ASPSCR1 ATP13A2 BRAF C10orf11 C4orf14 C6orf126 C9orf3 CACFD1 CASC10 CCDC126 CCDC171 CCDC53 CCDC87 CD79B CDC123 CENPW CEP120 CLIC6 CLUAP1 CROCC CTB-36H16.2 CTC-228N24.3 CTSF CTSS DARS DCAF16 DCXR DHDDS DIRAS3 EBPL EFEMP1 EIF2AK4 FAM136A FBN2 FLJ33630 FOXN2 FOXP1 GDF5 GPX1 GSDMC GSK3A HORMAD1 HORMAD2 HSD3B7 INTS12 IPO8 JAG1 KAT8 KCNK7 KIAA1614 LIME1 LMCD1 LOC285733 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAN2C1 MDM4 METTL22 MIR4519 MST1L MST1P2 MYST1 NCAPG NFAT5 NOB1 NOV NSFP1 PCDHB5 PDIK1L PELI3 PKDCC PLCD3 PLEKHM1P PPA2 PSMA4 PSMC5 PTCH1 QSOX2 RAD9A RGS12 RIN3 RNF123 ROM1 RP11-1055B8.4 RP11-108M9.5 RP11-196G11.2 RP11-250B2.6 RP1-125I3.2 RP11-382A20.2 RP11-422P24.10 RP11-425D10.10 RP11-669E14.6 RP11-78I14.1 RP11-967K21.1 RPS20 RPS6KA1 RRP15 SAR1B SCAND2P SCMH1 SEPN1 SETD1A SETDB1 SF3B2 SH3BGRL3 SHKBP1 SIK3 SLC12A2 SLC25A21 SMG7 SNAI3-AS1 STX1B TRIM63 TULP4 UBXN2A USP14 WDR18 WHAMM WNT3 WNT4 ZC3H11B ZCCHC24 ZDHHC24 ZNF438 ZNF76
Neuroticism	2.26	19	12	26.7	-0.37	1.0e-01	AAGAB ARL17A C11orf49 C1QTNF4 CENPW GPX1 HORMAD2 HSD3B7 LRRC37A LRRC37A2 MTCH2 MYST1 NSFP1 PTCH1 RP11-196G11.2 RP11-669E14.6 SETD1A STX1B WNT3
Chronotype (morning person)	1.36	8	3	6.7	-0.98	2.8e-05	ACP2 C1QTNF4 CRIPAK CTSS CYB561 HORMAD1 LOC147727 SETDB1
Hair Pigment	0.74	29	21	46.7	-0.14	4.5e-01	ACP2 ASPSCR1 BRAF C11orf49 C1QTNF4 C4orf14 CCDC87 CHMP1A CTC-228N24.3 DCXR DDB2 E2F1 FAM136A GDF5 HIST2H2AA3 L3MBTL3 LOC147727 LRRC37A LRRC37A2 MRGPRF MTCH2 RP11-268J15.5 RP11-669E14.6 RP5-890E16.2 SNAI3-AS1 TP53INP2 TULP4 ZCCHC24 ZNF76
Tanning	0.90	11	10	22.2	0.53	9.2e-02	ADCY3 C1QTNF4 CHMP1A CTSS E2F1 GDF5 HORMAD1 NOX4 SETDB1 SNAI3-AS1 TP53INP2
Hand grip strength (left)	4.53	47	27	60.0	0.95	7.2e-30	ADAM11 ADCY3 AOC1 ARFGEF2 AXIN2 BRAF C1QTNF4 CCDC53 CCDC87 CD79B CHMP1A CRIPAK CTD-3074O7.12 CYB561 DARS DCAF16 DLG5 FER FOXP1 GDF5 H1FX JAG1 JMJD4 L3MBTL3 LOXL1-AS1 LRRC37A LRRC37A2 MTCH2 NCAPG NCOA1 NOB1 PIGF PIP4K2B PKDCC PPP3R1 PSMC5 RAD9A RFT1 RP11-250B2.6 RP11-669E14.6 SETD1A SETDB1 TMEM180 TRA2A WNT3 ZCCHC24 ZNF76
Number of treatments/medications taken	1.77	4	0	0.0	-0.97	1.1e-03	CASC10 DCAF16 GPX1 NCAPG
Sensitivity / hurt feelings	1.86	6	5	11.1	-0.78	6.7e-02	ARL17A LRRC37A LRRC37A2 PTCH1 RP11-669E14.6 WNT3
Frequency of depressed mood in last 2 weeks	1.54	1	0	0.0	0.00	1.0e+00	WNT3
Relative age of first facial hair	2.07	6	5	11.1	-0.78	6.8e-02	LEMD3 LRRC37A LRRC37A2 RP11-65J21.3 RP11-669E14.6 WNT3
Ever had hysterectomy (womb removed)	1.29	1	0	0.0	0.00	1.0e+00	CASC10
Systolic blood pressure, automated reading	1.83	21	9	20.0	-0.56	4.6e-03	ACP2 ADCY3 C11orf49 C1QTNF4 CDC16 CDK6 DCAF16 EFEMP1 FER GPX1 LRRC37A2 NCAPG NOV NSFP1 PPA2 PPP3R1 RP11-1055B8.4 RP11-669E14.6 U91328.21 ZHX2 ZNF408
Medication: Metformin	1.72	2	1	2.2	0.00	1.0e+00	C1QTNF4 ZCCHC24
Pack years adult smoking proportion	2.25	4	1	2.2	-0.86	1.4e-01	CYB561 GPX1 PIAS4 PSMA4
Impedance of leg (right)	4.22	51	31	68.9	0.02	8.5e-01	AC103965.1 ADAM11 ADCY3 AOC1 AP3B1 ATP13A2 C1QTNF4 CD79B CDK6 CDO1 CEP120 CROCC CSPG4P11 CTC-228N24.3 CTD-3074O7.12 CTD-3076O17.1 CTSF CTSS FER FLJ33630 GDF5 GOLGA6L5 GPX1 H1FX HIST2H2AA3 KAT8 L3MBTL3 LOXL1-AS1 MRGPRF MST1L MST1P2 OTUD4 PACSIN1 PSMC5 PTCH1 RAD9A RFT1 RIN3 RP11-108M9.5 RP11-182J1.14 RP11-182J1.16 RP11-382A20.2 RP11-425D10.10 RP11-669E14.6 RPS20 SCAND2P SLC12A2 SNAI3-AS1 TSPAN3 UBE2Q2P1 WNT4
Leg fat-free mass (left)	5.15	91	67	148.9	0.90	1.2e-39	AC083843.1 ADAM11 ANAPC10 AOC1 AP3B1 ARFGEF2 AXIN2 CCDC53 CD79B CDC16 CDK6 CENPW CEP120 CNKSR1 CRIPAK CTC-228N24.3 DCAF16 DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 FLJ33630 GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HIST2H2AA3 HORMAD2 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LOC147727 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F MYST1 NARFL NCAPG NCOA1 NOV NOX4 OTUD4 PACSIN1 PDIK1L PIGC PIP4K2B PLEKHA1 PPA2 PPP3R1 PSMC3 PSMC5 PTCH1 RAB24 RAD9A RIN3 RP11-109P14.10 RP11-196G18.24 RP1-125I3.2 RP11-268J15.5 RP11-425D10.10 RP11-78I14.1 RP11-977G19.11 RPS20 SCMH1 SETD1A SH3BGRL3 SLC12A2 SMARCD2 TGFB2 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZCCHC24 ZNF500 ZNF638 ZNF76
Trunk fat percentage	3.19	47	34	75.6	0.03	8.5e-01	AAGAB AC103965.1 ADCY3 AP3B1 ARL17A C1QTNF4 CASC10 CCDC171 CENPW CSPG4P11 CTD-3076O17.1 DARS EFEMP1 FBN2 FLJ33630 FOXP1 GNA12 GOLGA6L5 HIST2H2AA3 HSD3B7 KAT8 LIME1 LRRC37A2 MTCH2 MYST1 NOB1 NSFP1 OTUD4 PACSIN1 PIAS4 PSMC5 RAD9A RIN3 ROM1 RP11-182J1.14 RP11-182J1.16 RP11-196G11.2 RP11-196G18.24 RP11-669E14.6 RP11-78I14.1 SCAND2P SETD1A STX1B UBE2Q2P1 WNT3 ZC3H11B ZNF500
Hand grip strength (right)	4.49	44	28	62.2	0.96	1.8e-30	ADAM11 ADCY3 ANGPTL1 AOC1 ARFGEF2 AXIN2 C1QTNF4 CCDC53 CD79B CRIPAK CYB561 DARS DCAF16 DLG5 GDF5 H1FX HABP4 JAG1 JMJD4 L3MBTL3 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 MTCH2 NCAPG NCOA1 NOB1 PIP4K2B PLCD3 PPP3R1 PSMC5 RAD9A RFT1 RP11-250B2.6 RP11-669E14.6 SCMH1 SMARCD2 TMEM180 TRA2A TULP4 WNT3 ZCCHC24 ZNF76
Current tobacco smoking	1.21	2	1	2.2	0.00	1.0e+00	LIME1 MTCH2
Maternal smoking around birth	1.49	1	0	0.0	0.00	1.0e+00	CASC10
Fed-up feelings	1.91	8	6	13.3	-0.95	3.9e-04	C11orf49 GPX1 HORMAD2 LRRC37A LRRC37A2 RP11-669E14.6 WNT3 ZNF408
Relative age voice broke	1.73	6	5	11.1	-0.83	4.1e-02	LRRC37A LRRC37A2 RP11-65J21.3 RP11-669E14.6 SCMH1 WNT3
Taking other prescription medications	1.45	2	0	0.0	0.00	1.0e+00	AHI1 GPX1
Age when periods started (menarche)	1.84	12	8	17.8	0.40	1.6e-01	C1QTNF4 CDC16 CENPW GPX1 MTCH2 NFAT5 NOB1 PSMB4 RP11-422P24.10 RP11-65J21.3 SAR1B SCMH1
Bilateral oophorectomy (both ovaries removed)	1.23	1	1	2.2	0.00	1.0e+00	WNT4
Heel bone mineral density (BMD) T-score, automated (left)	1.98	12	7	15.6	-0.09	7.8e-01	C11orf49 CDK6 CRIPAK DLEU2 EBPL JAG1 MRGPRF PKDCC PTCH1 WNT4 ZNF169 ZNF408
High blood pressure	1.86	12	6	13.3	-0.82	1.8e-04	ACP2 C11orf49 CHMP1A DCAF16 DDB2 KAT8 MYST1 NCAPG PIAS4 SETD1A U91328.21 ZNF408
Hayfever, allergic rhinitis or eczema	1.08	3	2	4.4	0.00	1.0e+00	AHI1 LIME1 TMEM180
Medication: Levothyroxine sodium	1.16	1	1	2.2	0.00	1.0e+00	HORMAD2
Sitting height	9.01	155	133	295.6	0.93	3.5e-80	AC083843.1 AC103965.1 ADAM11 ADCY3 ANAPC10 AOC1 AP3B1 ARFGEF2 ARL17A ASPSCR1 ATP13A2 AXIN2 C11orf49 C1QTNF4 C9orf3 CACFD1 CAMLG CCDC126 CCDC171 CCDC47 CD79B CDC16 CDK6 CDO1 CENPW CEP120 CHMP1A CMIP CNKSR1 CRIPAK CROCC CSPG4P11 CTD-3076O17.1 DCAF16 DCXR DDB2 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 ERCC6L2 ESPNP FAM136A GDF5 GNA12 GOLGA6L5 GPR126 GSDMC GSK3A H1FX H6PD HABP4 HAPLN3 HIST2H2AA3 HORMAD2 ICAM2 JAG1 JMJD4 KCNK7 KIAA1614 L3MBTL3 LEMD3 LOC147727 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTCH2 MTTP MYO1F MYO9A NARFL NCAPG NCOA1 NFAT5 NOB1 NOV OTUD4 PACSIN1 PACSIN2 PCDHB5 PDIK1L PIGC PIGF PIP4K2B PKDCC PLCD3 PLEKHA1 PPA2 PPP3R1 PSMC3 PSMC5 PTCH1 QSOX2 RAB24 RAD9A RFT1 RGS12 RP11-1055B8.4 RP11-108M9.5 RP11-109P14.10 RP11-182J1.14 RP11-182J1.16 RP11-196G18.24 RP11-250B2.6 RP1-125I3.2 RP11-425D10.10 RP11-435O5.4 RP11-65J21.3 RP11-669E14.6 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RP1-93H18.7 RPS20 RPS6KA1 RRP15 RSPH6A SAR1B SCMH1 SEPN1 SERPINF1 SH3BGRL3 SLC16A9 SLC25A21 SMARCD2 SNAI3-AS1 TGFB2 TMED6 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBE2Q2P1 UBXN2A WNT3 WNT4 ZC3H11B ZCCHC24 ZHX2 ZNF169 ZNF500 ZNF638 ZNF76
Chronic bronchitis/emphysema (father)	1.63	1	1	2.2	0.00	1.0e+00	PSMA4
Body mass index (BMI)	2.23	32	17	37.8	-0.69	1.1e-06	AC092667.2 ADCY3 AP3B1 ARFGEF2 ATP13A2 C1QTNF4 CASC10 CCDC171 CCDC87 CEP120 CTSF DARS DCAF16 FOXP1 GPX1 HSD3B7 KAT8 L3MBTL3 MTCH2 MYST1 NOB1 OTUD4 PACSIN1 PIAS4 PIGF RFT1 RP5-890E16.2 SAR1B SETD1A STX1B TMED6 TSPAN3
Impedance of leg (left)	4.30	48	30	66.7	0.03	8.0e-01	AC103965.1 ADAM11 ADCY3 AOC1 AP3B1 ATP13A2 C1QTNF4 CD79B CDO1 CEP120 CROCC CSPG4P11 CTC-228N24.3 CTD-3074O7.12 CTD-3076O17.1 CTSF CTSS FLJ33630 GDF5 GOLGA6L5 GPR126 GPX1 H1FX KAT8 L3MBTL3 LOXL1-AS1 LRRC37A2 MRGPRF MST1L MST1P2 OTUD4 PACSIN1 PPA2 PSMC5 RAD9A RIN3 RP11-182J1.14 RP11-182J1.16 RP11-382A20.2 RP11-425D10.10 RP11-669E14.6 RPS20 SCAND2P SLC12A2 TSPAN3 UBE2Q2P1 WNT3 WNT4
Leg predicted mass (left)	5.14	91	68	151.1	0.90	1.2e-40	AC083843.1 ADAM11 ANAPC10 AOC1 AP3B1 ARFGEF2 AXIN2 CCDC53 CD79B CDC16 CDK6 CENPW CEP120 CNKSR1 CRIPAK CTC-228N24.3 DCAF16 DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 FLJ33630 GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HIST2H2AA3 HORMAD2 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LOC147727 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F MYST1 NARFL NCAPG NCOA1 NOV NOX4 OTUD4 PACSIN1 PDIK1L PIGC PIP4K2B PLEKHA1 PPA2 PPP3R1 PSMC3 PSMC5 PTCH1 RAB24 RAD9A RIN3 RP11-109P14.10 RP11-196G18.24 RP1-125I3.2 RP11-268J15.5 RP11-425D10.10 RP11-78I14.1 RP11-977G19.11 RPS20 SCMH1 SETD1A SH3BGRL3 SLC12A2 SMARCD2 TGFB2 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZCCHC24 ZNF500 ZNF638 ZNF76
Trunk fat mass	3.07	53	38	84.4	0.36	4.3e-03	AAGAB AC103965.1 ADCY3 ANAPC10 AP3B1 ARL17A C1QTNF4 CASC10 CCDC171 CDK6 CEP120 CSPG4P11 CTD-3076O17.1 E2F1 EFEMP1 EIF2AK4 FBN2 FOXP1 GDF5 GNA12 GOLGA6L5 GPR126 GPX1 H1FX HAPLN3 HIST2H2AA3 HSD3B7 KAT8 L3MBTL3 LIME1 LRRC37A2 MPHOSPH6 MTCH2 MYST1 NOB1 NSFP1 OTUD4 PACSIN1 PIAS4 PLEKHA1 RAD9A RP11-182J1.14 RP11-182J1.16 RP11-196G18.24 RP11-78I14.1 SCAND2P SETD1A STX1B TP53INP2 UBE2Q2P1 WNT3 ZC3H11B ZNF500
Waist circumference	2.17	27	23	51.1	-0.29	1.1e-01	AAGAB AC092667.2 ADCY3 AP3B1 C1QTNF4 CASC10 CCDC171 CDK6 CEP120 GNA12 HSD3B7 KAT8 LIME1 MTCH2 MYST1 NOB1 OTUD4 PACSIN1 PIAS4 RAD9A RP11-182J1.16 RP11-78I14.1 SAR1B SETD1A STX1B ZCCHC24 ZNF500
Number of incorrect matches in round	1.63	3	0	0.0	0.00	1.0e+00	KAT8 MYST1 SETD1A
Past tobacco smoking	1.29	5	0	0.0	0.21	7.4e-01	C4orf14 CASC10 NOB1 RP11-977G19.11 TMEM180
Alcohol usually taken with meals	1.53	1	1	2.2	0.00	1.0e+00	FOXP1
Nervous feelings	1.82	11	6	13.3	-0.66	2.7e-02	ARL17A CENPW HSD3B7 KAT8 LRRC37A LRRC37A2 MYST1 RP11-669E14.6 SETD1A STX1B WNT3
Frequency of tenseness / restlessness in last 2 weeks	1.63	6	3	6.7	-0.83	3.9e-02	GPX1 LRRC37A LRRC37A2 RP11-268J15.5 RP11-669E14.6 WNT3
Hearing difficulty/problems with background noise	1.40	2	0	0.0	0.00	1.0e+00	C11orf49 RP11-669E14.6
Hair/balding pattern: Pattern 2	1.52	5	3	6.7	-0.97	4.9e-03	C10orf11 LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Had other major operations	1.24	1	0	0.0	0.00	1.0e+00	PPA2
Forced vital capacity (FVC)	12.26	233	203	451.1	1.00	1.8e-296	AAGAB AC083843.1 AC092667.2 AC103965.1 ACP2 ADAM11 ADAMTS6 ADCY3 AHI1 ANAPC10 ANGPTL1 ANKRD13B AOC1 AP3B1 ARFGEF2 ARL17A ASPSCR1 ATP13A2 AXIN2 BRAF C10orf11 C11orf49 C1QTNF4 C21orf34 C4orf14 C6orf126 C9orf3 CACFD1 CAMLG CASC10 CCDC126 CCDC171 CCDC47 CCDC53 CCDC87 CD79B CDC123 CDC16 CDK6 CDO1 CENPW CEP120 CHMP1A CLIC6 CLUAP1 CMIP CNKSR1 CRIPAK CROCC CSPG4P11 CTB-36H16.2 CTC-228N24.3 CTD-3074O7.12 CTD-3076O17.1 CTSF CTSS CYB561 DARS DCAF16 DCXR DDB2 DHDDS DIRAS3 DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 ERCC6L2 ESPNP FAM136A FBN2 FER FILIP1 FLJ33630 FOXN2 FOXP1 GDF5 GNA12 GOLGA6L5 GPR126 GPX1 GSDMC GSK3A H1FX H6PD HABP4 HAPLN3 HIST2H2AA3 HORMAD1 HORMAD2 HSD3B7 ICAM2 INTS12 IPO8 JAG1 JMJD4 KAT8 KCNK7 KIAA1468 KIAA1614 L3MBTL3 LEMD3 LIME1 LMCD1 LOC147727 LOC285733 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAN2C1 MDM4 METTL22 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTCH2 MTTP MYO1F MYO9A MYST1 NARFL NCAPG NCOA1 NFAT5 NOB1 NOV NOX4 NSFP1 OTUD4 PACSIN1 PACSIN2 PCDHB5 PDIK1L PELI3 PIAS4 PIGC PIGF PIP4K2B PKDCC PLCD3 PLEKHA1 PLEKHM1P PPA2 PPP3R1 PSMA4 PSMB4 PSMC3 PSMC5 PTCH1 QSOX2 RAB24 RAD9A RFT1 RGS12 RIN3 RNF123 ROM1 RP11-1055B8.4 RP11-108M9.5 RP11-109P14.10 RP11-182J1.14 RP11-182J1.16 RP11-196G11.2 RP11-196G18.24 RP11-250B2.6 RP1-125I3.2 RP11-268J15.5 RP11-382A20.2 RP11-425D10.10 RP11-435O5.4 RP11-65J21.3 RP11-669E14.6 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RP1-93H18.7 RP5-890E16.2 RPS20 RPS6KA1 RRP15 RSPH6A SAR1B SCAND2P SCMH1 SEPN1 SERPINF1 SETD1A SETDB1 SF3B2 SH3BGRL3 SHKBP1 SIK3 SLC12A2 SLC16A9 SLC25A21 SMARCD2 SMG7 SNAI3-AS1 SNX21 STX1B TGFB2 TMED6 TMEM180 TNFAIP8L3 TP53INP2 TRA2A TRIM63 TSEN15 TSPAN3 TULP4 U91328.21 UBE2Q2P1 UBXN2A USP14 WDR18 WHAMM WNT3 WNT4 ZC3H11B ZCCHC24 ZDHHC24 ZHX2 ZNF169 ZNF438 ZNF500 ZNF76
Heel bone mineral density (BMD) T-score, automated (right)	2.13	16	8	17.8	-0.18	5.0e-01	ACP2 C11orf49 C4orf14 CDK6 CRIPAK DCAF16 DDB2 DLEU2 EBPL MRGPRF NCAPG PKDCC PTCH1 WNT4 ZNF169 ZNF408
Ever unenthusiastic/disinterested for a whole week	1.33	3	0	0.0	0.00	1.0e+00	LRRC37A LRRC37A2 WNT3
Qualifications: None of the above	1.45	6	1	2.2	-0.93	7.1e-03	DCAF16 FOXP1 GPX1 PPA2 RFT1 RNF123
Mouth/teeth dental problems	1.15	1	0	0.0	0.00	1.0e+00	WNT3
Allergy	1.20	5	4	8.9	0.71	1.2e-01	AAGAB AHI1 CTD-3074O7.12 LIME1 TMEM180
Diabetes (self-reported)	1.83	5	1	2.2	-0.97	1.2e-03	CLUAP1 CTC-228N24.3 FLJ33630 MAN2C1 ZCCHC24
Medication: Simvastatin	1.61	2	0	0.0	0.00	1.0e+00	CTC-228N24.3 DCAF16
Fluid intelligence score	2.00	10	5	11.1	0.84	1.8e-04	C1QTNF4 DCAF16 FOXP1 MTCH2 NCAPG PPA2 PTCH1 RNF123 U91328.21 ZNF638
Illnesses of siblings	1.69	1	0	0.0	0.00	1.0e+00	KAT8
Neuroticism score	2.15	14	10	22.2	-0.19	4.8e-01	C1QTNF4 GPX1 HORMAD2 HSD3B7 LRRC37A LRRC37A2 MTCH2 MYST1 PTCH1 RP11-196G11.2 RP11-669E14.6 SETD1A STX1B WNT3
Weight	3.59	68	50	111.1	0.70	4.0e-13	AAGAB AC103965.1 ANAPC10 AP3B1 C1QTNF4 CASC10 CCDC171 CD79B CDC16 CDK6 CENPW CEP120 CRIPAK CTD-3076O17.1 DCAF16 DLEU2 E2F1 EBPL EFEMP1 EIF2AK4 GDF5 GNA12 GPR126 GPX1 H1FX HAPLN3 HIST2H2AA3 HORMAD2 HSD3B7 KAT8 L3MBTL3 LIME1 LOC147727 MPHOSPH6 MRGPRF MRPL42 MYO1F MYST1 NARFL NCAPG NOX4 OTUD4 PACSIN1 PLEKHA1 PPA2 PSMC5 RAD9A RP11-182J1.14 RP11-182J1.16 RP11-196G18.24 RP11-425D10.10 RP11-78I14.1 RPS20 SCMH1 SERPINF1 SETD1A SMARCD2 STX1B TGFB2 TMEM180 TP53INP2 TRA2A TSEN15 WNT4 ZC3H11B ZCCHC24 ZNF500 ZNF638
Impedance of arm (right)	2.86	50	36	80.0	0.43	7.6e-04	AAGAB AC103965.1 AOC1 ARL17A ATP13A2 CASC10 CD79B CENPW CEP120 CSPG4P11 CTD-3076O17.1 EFEMP1 FBN2 FER GOLGA6L5 GPR126 GPX1 H6PD HIST2H2AA3 HORMAD1 KAT8 L3MBTL3 LOXL1-AS1 LRPAP1 LRRC37A2 MRPL42 MST1L MST1P2 NSFP1 PACSIN1 PPP3R1 PSMC5 QSOX2 RFT1 RIN3 ROM1 RP11-108M9.5 RP11-182J1.14 RP11-182J1.16 RP11-196G18.24 RP1-125I3.2 RP11-669E14.6 RP5-890E16.2 RPS20 SAR1B SCMH1 TSPAN3 UBE2Q2P1 WNT3 ZC3H11B
Arm fat percentage (right)	2.88	40	24	53.3	-0.67	1.5e-07	AAGAB ACP2 ADCY3 ANKRD13B AP3B1 ARFGEF2 ARL17A C1QTNF4 CASC10 CCDC171 CCDC87 CD79B CENPW CTD-3074O7.12 CTSF DCAF16 DDB2 FBN2 FOXP1 GPX1 HABP4 HIST2H2AA3 HSD3B7 KAT8 LIME1 MTCH2 MYST1 NCAPG NOB1 NOV NSFP1 PIAS4 PIGF PSMC5 RP11-196G18.24 RP11-78I14.1 SAR1B SETD1A STX1B ZNF76
Trunk fat-free mass	6.70	115	95	211.1	0.94	7.5e-62	AC083843.1 ADAM11 ADCY3 ANAPC10 AOC1 AP3B1 ARFGEF2 ATP13A2 AXIN2 C11orf49 C1QTNF4 C6orf126 C9orf3 CCDC47 CCDC53 CD79B CDC16 CDK6 CENPW CEP120 CHMP1A CNKSR1 CRIPAK CTC-228N24.3 DCAF16 DDB2 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 FAM136A FLJ33630 GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ICAM2 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LOC147727 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1L MTCH2 MYO1F MYO9A NARFL NCAPG NCOA1 NOV NOX4 OTUD4 PACSIN1 PDIK1L PIGC PIP4K2B PLEKHA1 PLEKHM1P PPA2 PPP3R1 PSMC3 PSMC5 PTCH1 RAB24 RAD9A RFT1 RIN3 RP11-109P14.10 RP11-182J1.16 RP11-250B2.6 RP1-125I3.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-65J21.3 RP11-78I14.1 RP11-977G19.11 RPS20 RPS6KA1 SAR1B SCMH1 SERPINF1 SH3BGRL3 SLC12A2 SMARCD2 SNAI3-AS1 TGFB2 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76
Hip circumference	3.10	49	37	82.2	0.36	6.6e-03	AC103965.1 ADCY3 ANAPC10 AP3B1 C1QTNF4 CASC10 CCDC171 CD79B CDK6 CEP120 DLEU2 E2F1 EBPL EFEMP1 EIF2AK4 GDF5 GNA12 GPR126 GPX1 H1FX HIST2H2AA3 HSD3B7 KAT8 L3MBTL3 LIME1 LOC147727 MPHOSPH6 MTCH2 MYST1 NARFL NOB1 NOX4 OTUD4 PACSIN1 PLEKHA1 RAD9A RP11-182J1.16 RP11-196G11.2 RP11-196G18.24 RP11-425D10.10 RP11-78I14.1 RPS20 SCMH1 SETD1A STX1B TP53INP2 WNT4 ZC3H11B ZNF500
Time employed in main current job	1.18	2	1	2.2	0.00	1.0e+00	LRRC37A2 WNT3
Father's age at death	1.39	2	1	2.2	0.00	1.0e+00	GPX1 PSMA4
Worrier / anxious feelings	1.62	9	5	11.1	-0.15	6.5e-01	HSD3B7 LRRC37A2 MYST1 PTCH1 RP11-669E14.6 SETD1A STX1B TMEM180 WNT3
Frequency of tiredness / lethargy in last 2 weeks	1.44	2	0	0.0	0.00	1.0e+00	GPX1 SLC25A21
Hair/balding pattern: Pattern 3	2.32	5	5	11.1	0.65	2.3e-01	CENPW LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Number of live births	1.19	4	1	2.2	-0.98	2.2e-02	LRRC37A LRRC37A2 WNT3 WNT4
Forced expiratory volume in 1-second (FEV1)	10.23	187	140	311.1	0.98	1.1e-160	AC083843.1 AC092667.2 AC103965.1 ADAMTS6 ADCY3 AHI1 ANAPC10 ANGPTL1 AOC1 AP3B1 ARFGEF2 ARL17A ASPSCR1 ATP13A2 AXIN2 BRAF C10orf11 C1QTNF4 C4orf14 C6orf126 CACFD1 CAMLG CCDC126 CCDC171 CCDC53 CCDC87 CD79B CDC123 CDC16 CDK6 CDO1 CENPW CEP120 CHMP1A CLUAP1 CMIP CNKSR1 CRIPAK CSPG4P11 CTB-36H16.2 CTD-3074O7.12 CTD-3076O17.1 CTSF CTSS CYB561 DARS DCAF16 DCXR DHDDS DIRAS3 DLEU2 DLG5 EBPL EFEMP1 EIF2AK4 ERCC6L2 FAM136A FER FILIP1 FOXP1 GDF5 GOLGA6L5 GPX1 GSDMC GSK3A H1FX H6PD HABP4 HAPLN3 HIST2H2AA3 HORMAD2 HSD3B7 ICAM2 INTS12 IPO8 JAG1 JMJD4 KAT8 KIAA1468 KIAA1614 L3MBTL3 LEMD3 LIME1 LOC147727 LOC285733 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAN2C1 MDM4 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTCH2 MTTP MYO9A MYST1 NCAPG NFAT5 NOB1 NOV NOX4 NSFP1 OTUD4 PACSIN1 PCDHB5 PDIK1L PELI3 PIAS4 PIGC PKDCC PLCD3 PLEKHM1P PPA2 PSMA4 PSMB4 PSMC5 PTCH1 QSOX2 RAB24 RAD9A RFT1 RGS12 RIN3 RNF123 ROM1 RP11-1055B8.4 RP11-109P14.10 RP11-182J1.14 RP11-182J1.16 RP11-196G11.2 RP11-196G18.24 RP11-250B2.6 RP1-125I3.2 RP11-382A20.2 RP11-425D10.10 RP11-435O5.4 RP11-65J21.3 RP11-669E14.6 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RP1-93H18.7 RPS20 RPS6KA1 RSPH6A SAR1B SCAND2P SCMH1 SEPN1 SERPINF1 SETD1A SETDB1 SF3B2 SH3BGRL3 SLC12A2 SLC25A21 SMARCD2 SMG7 SNAI3-AS1 STX1B TGFB2 TMED6 TMEM180 TNFAIP8L3 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 U91328.21 UBE2Q2P1 UBXN2A WHAMM WNT3 WNT4 ZCCHC24 ZDHHC24 ZHX2 ZNF169 ZNF408 ZNF500 ZNF76
Pulse rate	1.20	2	1	2.2	0.00	1.0e+00	CEP120 ROM1
Qualifications: A levels/AS levels or equivalent	1.62	4	1	2.2	0.97	3.5e-02	DCAF16 GDF5 GPX1 RNF123
Mouth/teeth dental problems: Dentures	1.40	3	0	0.0	0.00	1.0e+00	GPX1 PSMA4 RP11-1055B8.4
Asthma	1.61	5	3	6.7	-0.67	1.4e-01	AAGAB AHI1 CTD-3074O7.12 U91328.21 ZNF76
Medication: Ibuprofen (e.g. Nurofen)	1.24	1	0	0.0	0.00	1.0e+00	U91328.21
Medication: Cholesterol lowering	1.46	1	0	0.0	0.00	1.0e+00	LOC147727
Lung cancer (father)	1.42	1	1	2.2	0.00	1.0e+00	PSMA4
Forced expiratory volume in 1-second (FEV1), Best measure	10.46	187	129	286.7	0.98	1.1e-166	AC083843.1 AC092667.2 AC103965.1 ACP2 ADAM11 ADAMTS6 ADCY3 AHI1 ANAPC10 ANGPTL1 AOC1 AP3B1 ARFGEF2 ARL17A ASPSCR1 ATP13A2 AXIN2 BRAF C10orf11 C11orf49 C1QTNF4 C4orf14 C6orf126 CACFD1 CAMLG CCDC53 CCDC87 CD79B CDC123 CDC16 CDK6 CDO1 CENPW CEP120 CLUAP1 CMIP CNKSR1 CRIPAK CSPG4P11 CTB-36H16.2 CTD-3074O7.12 CTD-3076O17.1 CTSF CTSS CYB561 DARS DCAF16 DCXR DHDDS DIRAS3 DLEU2 DLG5 EBPL EFEMP1 ERCC6L2 FAM136A FBN2 FER FILIP1 FOXP1 GDF5 GOLGA6L5 GPX1 GSDMC GSK3A H1FX H6PD HABP4 HAPLN3 HORMAD2 HSD3B7 ICAM2 INTS12 IPO8 JAG1 JMJD4 KAT8 KIAA1468 KIAA1614 L3MBTL3 LEMD3 LIME1 LOC147727 LOC285733 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAN2C1 MDM4 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTCH2 MTTP MYO1F MYO9A MYST1 NCAPG NFAT5 NOB1 NSFP1 OTUD4 PACSIN1 PCDHB5 PDIK1L PELI3 PIAS4 PIGC PKDCC PLCD3 PLEKHM1P PPA2 PSMA4 PSMB4 PSMC5 PTCH1 QSOX2 RAB24 RAD9A RFT1 RGS12 RIN3 RNF123 ROM1 RP11-1055B8.4 RP11-109P14.10 RP11-182J1.14 RP11-182J1.16 RP11-196G11.2 RP11-196G18.24 RP11-250B2.6 RP1-125I3.2 RP11-382A20.2 RP11-425D10.10 RP11-65J21.3 RP11-669E14.6 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RP1-93H18.7 RPS20 RPS6KA1 RSPH6A SAR1B SCAND2P SCMH1 SEPN1 SERPINF1 SETD1A SETDB1 SH3BGRL3 SHKBP1 SLC12A2 SLC25A21 SMARCD2 SMG7 SNAI3-AS1 STX1B TGFB2 TMED6 TMEM180 TNFAIP8L3 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 U91328.21 UBE2Q2P1 UBXN2A WDR18 WHAMM WNT3 WNT4 ZC3H11B ZCCHC24 ZDHHC24 ZHX2 ZNF169 ZNF408 ZNF438 ZNF500 ZNF76
Impedance of arm (left)	2.88	49	34	75.6	0.48	1.3e-04	AC103965.1 AOC1 ARL17A ATP13A2 CASC10 CD79B CENPW CEP120 CSPG4P11 CTD-3076O17.1 EFEMP1 FBN2 FER GNA12 GOLGA6L5 GPR126 GPX1 H6PD HIST2H2AA3 HORMAD1 KAT8 L3MBTL3 LOXL1-AS1 LRRC37A LRRC37A2 MRPL42 MST1L MST1P2 NSFP1 PACSIN1 PSMC5 RFT1 RIN3 ROM1 RP11-108M9.5 RP11-182J1.14 RP11-182J1.16 RP11-196G18.24 RP11-669E14.6 RP5-890E16.2 RPS20 SAR1B SCAND2P SCMH1 SHKBP1 TSPAN3 UBE2Q2P1 WNT3 ZC3H11B
Arm fat mass (right)	2.18	31	22	48.9	-0.28	9.4e-02	AAGAB AC092667.2 ADCY3 AP3B1 C1QTNF4 CASC10 CCDC171 CCDC87 CDK6 CEP120 CTSF FOXP1 GNA12 GPX1 HIST2H2AA3 HSD3B7 KAT8 L3MBTL3 LIME1 MTCH2 MYST1 NOB1 OTUD4 PACSIN1 PIAS4 RP11-196G18.24 RP11-78I14.1 SETD1A STX1B TP53INP2 ZNF500
Trunk predicted mass	6.70	115	94	208.9	0.94	7.2e-62	AC083843.1 ADAM11 ADCY3 ANAPC10 AOC1 AP3B1 ARFGEF2 ATP13A2 AXIN2 C11orf49 C1QTNF4 C6orf126 C9orf3 CCDC47 CCDC53 CD79B CDC16 CDK6 CENPW CEP120 CHMP1A CNKSR1 CRIPAK CTC-228N24.3 DCAF16 DDB2 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 FAM136A FLJ33630 GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ICAM2 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LOC147727 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1L MTCH2 MYO1F MYO9A NARFL NCAPG NCOA1 NOV NOX4 OTUD4 PACSIN1 PDIK1L PIGC PIP4K2B PLEKHA1 PLEKHM1P PPA2 PPP3R1 PSMC3 PSMC5 PTCH1 RAB24 RAD9A RFT1 RIN3 RP11-109P14.10 RP11-182J1.16 RP11-250B2.6 RP1-125I3.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-65J21.3 RP11-78I14.1 RP11-977G19.11 RPS20 RPS6KA1 SAR1B SCMH1 SERPINF1 SH3BGRL3 SLC12A2 SMARCD2 SNAI3-AS1 TGFB2 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76
Standing height	10.30	187	169	375.6	0.94	5.1e-103	AAGAB AC103965.1 ACP2 ADAM11 ADAMTS6 ADCY3 ANAPC10 ANKRD13B AOC1 AP3B1 ARFGEF2 ARL17A ASPSCR1 ATP13A2 AXIN2 BRAF C11orf49 C1QTNF4 C4orf14 C6orf126 C9orf3 CACFD1 CAMLG CCDC126 CCDC47 CCDC53 CCDC87 CD79B CDC16 CDK6 CDO1 CENPW CEP120 CHMP1A CMIP CNKSR1 CRIPAK CROCC CSPG4P11 CTC-228N24.3 CTD-3074O7.12 CTD-3076O17.1 CTSF CYB561 DCAF16 DDB2 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 ERCC6L2 ESPNP FAM136A FER FILIP1 FLJ33630 GDF5 GNA12 GOLGA6L5 GPR126 GPX1 GSDMC GSK3A H1FX H6PD HABP4 HAPLN3 HIST2H2AA3 HORMAD2 ICAM2 IPO8 JAG1 JMJD4 KCNK7 KIAA1468 KIAA1614 L3MBTL3 LEMD3 LOC147727 LOC285733 LOXL1-AS1 LRRC37A2 MAN2C1 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTCH2 MTTP MYO1F MYO9A NARFL NCAPG NCOA1 NFAT5 NOB1 NOV NOX4 NSFP1 OTUD4 PACSIN1 PACSIN2 PCDHB5 PDIK1L PELI3 PIAS4 PIGC PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PPA2 PPP3R1 PSMB4 PSMC3 PSMC5 PTCH1 QSOX2 RAB24 RAD9A RFT1 RGS12 RP11-1055B8.4 RP11-108M9.5 RP11-109P14.10 RP11-182J1.14 RP11-182J1.16 RP11-196G18.24 RP11-250B2.6 RP1-125I3.2 RP11-268J15.5 RP11-382A20.2 RP11-425D10.10 RP11-435O5.4 RP11-65J21.3 RP11-669E14.6 RP11-78I14.1 RP11-977G19.11 RP1-93H18.7 RP5-890E16.2 RPS20 RPS6KA1 RRP15 RSPH6A SAR1B SCAND2P SCMH1 SEPN1 SERPINF1 SF3B2 SH3BGRL3 SLC16A9 SLC25A21 SMARCD2 SNAI3-AS1 SNX21 TGFB2 TMED6 TMEM180 TNFAIP8L3 TP53INP2 TRA2A TRIM63 TSEN15 TSPAN3 TULP4 U91328.21 UBE2Q2P1 UBXN2A WNT3 WNT4 ZC3H11B ZCCHC24 ZHX2 ZNF169 ZNF408 ZNF438 ZNF500 ZNF638 ZNF76
Tense / 'highly strung'	1.69	5	4	8.9	0.05	9.2e-01	HSD3B7 KAT8 MYST1 SETD1A STX1B
Seen doctor (GP) for nerves, anxiety, tension or depression	1.65	4	0	0.0	-0.66	2.3e-01	CCDC87 CTD-3074O7.12 CTSF U91328.21
Hair/balding pattern: Pattern 4	2.97	11	8	17.8	0.30	3.7e-01	C10orf11 CENPW CNKSR1 CTB-36H16.2 DLG5 FAM136A LOC285733 LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Birth weight of first child	2.61	12	7	15.6	0.96	1.6e-08	ANAPC10 ASPSCR1 C6orf126 CTC-228N24.3 DCAF16 DCXR IPO8 OTUD4 PPA2 RP11-78I14.1 WNT4 ZNF76
Peak expiratory flow (PEF)	5.01	49	28	62.2	0.96	2.6e-30	ANAPC10 ARL17A ASPSCR1 C10orf11 C4orf14 CACFD1 CCDC53 CCDC87 CD79B CDC123 CHMP1A CTD-3074O7.12 CTSF DCAF16 DHDDS DLEU2 EBPL EFEMP1 GDF5 GSDMC H1FX LOC147727 LRRC37A LRRC37A2 MDM4 MPHOSPH6 MRGPRF MTCH2 NCAPG OTUD4 PELI3 PIAS4 PPA2 PSMC5 RAD9A RNF123 RP11-425D10.10 RP11-65J21.3 RP11-669E14.6 RPS6KA1 SF3B2 TGFB2 TP53INP2 TRIM63 UBXN2A WNT3 ZDHHC24 ZHX2 ZNF76
Qualifications: O levels/GCSEs or equivalent	1.25	1	1	2.2	0.00	1.0e+00	GPX1
Blood clot in the leg (DVT)	1.38	1	1	2.2	0.00	1.0e+00	CACFD1
Medication: Paracetamol	1.64	7	6	13.3	-0.73	6.4e-02	CASC10 GPX1 LRRC37A LRRC37A2 RP11-669E14.6 U91328.21 WNT3
Headache pain in last month	1.67	5	5	11.1	-0.83	8.3e-02	LRRC37A LRRC37A2 RP11-669E14.6 U91328.21 WNT3
Gout (self-reported)	1.18	2	1	2.2	0.00	1.0e+00	SLC16A9 U91328.21
Hypothyroidism/myxoedema (self-reported)	1.32	4	2	4.4	-0.14	8.6e-01	AHI1 HORMAD2 PLEKHA1 RP11-109P14.10
Medication: Ventolin 100micrograms inhaler	1.11	1	0	0.0	0.00	1.0e+00	AAGAB
Birth weight	3.05	21	10	22.2	0.89	2.9e-09	ANAPC10 C1QTNF4 C6orf126 CDK6 CENPW DCAF16 GNA12 GPR126 HORMAD2 L3MBTL3 MTCH2 NCAPG PPA2 PTCH1 RFT1 RP11-425D10.10 TRA2A TULP4 UBXN2A WNT4 ZNF76
Chronic bronchitis/emphysema (mother)	1.74	1	1	2.2	0.00	1.0e+00	PSMA4
High blood pressure (siblings)	1.68	2	1	2.2	0.00	1.0e+00	KAT8 MYST1
Body fat percentage	3.17	45	30	66.7	-0.45	6.4e-04	AAGAB AC103965.1 ADCY3 ANKRD13B AP3B1 ARFGEF2 C1QTNF4 CASC10 CCDC171 CD79B CENPW CTC-228N24.3 CTD-3076O17.1 DARS DCAF16 FBN2 FLJ33630 FOXP1 GNA12 GOLGA6L5 GPX1 HABP4 HIST2H2AA3 HSD3B7 KAT8 LIME1 MTCH2 MYST1 NOB1 NOV PIAS4 PSMC5 RIN3 ROM1 RP11-182J1.14 RP11-182J1.16 RP11-196G11.2 RP11-196G18.24 RP11-78I14.1 SAR1B SETD1A SLC12A2 STX1B UBE2Q2P1 ZC3H11B
Leg fat percentage (right)	3.69	43	30	66.7	-0.81	2.1e-13	AAGAB AC103965.1 ADCY3 ANKRD13B ARFGEF2 C1QTNF4 CASC10 CCDC171 CD79B CENPW CTC-228N24.3 DARS DCAF16 FLJ33630 FOXN2 FOXP1 GDF5 GPX1 GSK3A HABP4 HSD3B7 KAT8 LIME1 MTCH2 MYST1 NCAPG NOB1 NOV PIAS4 PIGF PLEKHM1P PSMC3 PSMC5 RIN3 RP11-182J1.16 RP11-196G11.2 SAR1B SETD1A SLC12A2 SMARCD2 SNAI3-AS1 STX1B ZCCHC24
Arm fat-free mass (right)	5.42	94	75	166.7	0.91	5.9e-42	AC083843.1 ADAM11 ANAPC10 AOC1 AP3B1 ARFGEF2 AXIN2 C1QTNF4 CASC10 CCDC53 CD79B CDC16 CDK6 CENPW CEP120 CHMP1A CNKSR1 CRIPAK DCAF16 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 GDF5 GNA12 GPR126 GPX1 GSDMC H1FX HABP4 HAPLN3 HORMAD2 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LOC147727 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F MYST1 NARFL NCAPG NCOA1 NOV OTUD4 PACSIN1 PDIK1L PIGC PLEKHA1 PPA2 PPP3R1 PSMC3 PSMC5 PTCH1 RAB24 RAD9A RIN3 RP11-182J1.16 RP11-250B2.6 RP1-125I3.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-65J21.3 RP11-78I14.1 RP11-977G19.11 RPS20 RPS6KA1 SCMH1 SERPINF1 SETD1A SH3BGRL3 SMARCD2 TGFB2 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 UBXN2A ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76
Comparative body size at age 10	2.30	15	10	22.2	-0.67	1.7e-03	ADCY3 AP3B1 ARL17A C1QTNF4 CMIP HSD3B7 KAT8 MTCH2 MYST1 NCOA1 NSFP1 RP11-196G11.2 SETD1A STX1B U91328.21
Worry too long after embarrassment	1.72	5	0	0.0	-0.16	8.0e-01	AHI1 PPA2 RGS12 RP11-669E14.6 WNT3
Wheeze or whistling in the chest in last year	1.75	3	1	2.2	0.00	1.0e+00	CCDC171 LIME1 STX1B
Age at first live birth	1.70	1	1	2.2	0.00	1.0e+00	GPX1
Health satisfaction	1.17	1	0	0.0	0.00	1.0e+00	CCDC87
Qualifications: College or University degree	1.81	16	9	20.0	0.93	2.6e-07	DCAF16 FOXP1 GDF5 GPX1 HABP4 LRRC37A LRRC37A2 MDM4 PPA2 RGS12 RNF123 RP11-1055B8.4 RP11-669E14.6 SMARCD2 SNX21 WNT3
Medication for pain relief, constipation, heartburn	1.50	7	4	8.9	0.50	2.5e-01	GPX1 LRRC37A LRRC37A2 PLCD3 RP11-669E14.6 U91328.21 WNT3
Neck or shoulder pain in last month	1.04	1	0	0.0	0.00	1.0e+00	GPX1
Medication: Blood pressure	1.67	4	1	2.2	-0.99	9.8e-03	ACP2 CDC16 DCAF16 FBN2
Medication: Allopurinol	1.25	1	0	0.0	0.00	1.0e+00	SLC16A9
Mean time to correctly identify matches	1.55	7	3	6.7	-0.04	9.3e-01	ARFGEF2 ARL17A C11orf49 L3MBTL3 NSFP1 PIAS4 ZNF638
Whole body fat mass	2.63	44	32	71.1	0.20	1.7e-01	AAGAB AC103965.1 ADCY3 ANAPC10 AP3B1 C1QTNF4 CASC10 CCDC171 CDK6 CEP120 CTD-3076O17.1 E2F1 EFEMP1 FBN2 FOXP1 GDF5 GNA12 GOLGA6L5 GPR126 GPX1 H1FX HIST2H2AA3 HSD3B7 KAT8 L3MBTL3 LIME1 MPHOSPH6 MTCH2 MYST1 NOB1 OTUD4 PACSIN1 PIAS4 RAD9A RP11-182J1.14 RP11-182J1.16 RP11-196G18.24 RP11-78I14.1 SETD1A STX1B TP53INP2 UBE2Q2P1 ZC3H11B ZNF500
Leg fat mass (right)	2.30	32	24	53.3	-0.29	7.9e-02	AAGAB AC103965.1 ADCY3 AP3B1 C1QTNF4 CASC10 CCDC171 CDK6 CTC-228N24.3 DARS FLJ33630 FOXP1 GNA12 GPX1 HSD3B7 KAT8 L3MBTL3 LIME1 MPHOSPH6 MTCH2 MYST1 NOB1 OTUD4 PACSIN1 PIAS4 RAD9A RP11-182J1.16 RP11-78I14.1 SAR1B SETD1A STX1B ZNF500
Arm predicted mass (right)	5.42	94	75	166.7	0.90	1.8e-41	AC083843.1 ADAM11 ANAPC10 AOC1 AP3B1 ARFGEF2 AXIN2 C1QTNF4 CASC10 CCDC53 CD79B CDC16 CDK6 CENPW CEP120 CHMP1A CNKSR1 CRIPAK DCAF16 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 GDF5 GNA12 GPR126 GPX1 GSDMC H1FX HABP4 HAPLN3 HORMAD2 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LOC147727 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F MYST1 NARFL NCAPG NCOA1 NOV OTUD4 PACSIN1 PDIK1L PIGC PLEKHA1 PPA2 PPP3R1 PSMC3 PSMC5 PTCH1 RAB24 RAD9A RIN3 RP11-182J1.16 RP11-250B2.6 RP1-125I3.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-65J21.3 RP11-78I14.1 RP11-977G19.11 RPS20 RPS6KA1 SCMH1 SERPINF1 SETD1A SH3BGRL3 SMARCD2 TGFB2 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 UBXN2A WNT4 ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76
Pulse rate, automated reading	1.66	12	5	11.1	-0.98	4.5e-10	AC103965.1 CEP120 DARS HABP4 MYO9A PDIK1L ROM1 RP11-1055B8.4 RP1-125I3.2 RP11-382A20.2 STX1B TRIM63
Alcohol intake frequency.	1.80	14	8	17.8	-0.96	4.7e-09	AC092667.2 C1QTNF4 FOXP1 KAT8 LRRC37A LRRC37A2 MTCH2 PPA2 RGS12 RP11-669E14.6 SETD1A TMED6 UBXN2A WNT3
Comparative height size at age 10	8.97	142	121	268.9	0.94	7.4e-83	AAGAB AC103965.1 ADAM11 ADAMTS6 ADCY3 ANAPC10 ANKRD13B AOC1 AP3B1 ARFGEF2 ARL17A ASPSCR1 ATP13A2 AXIN2 C11orf49 C1QTNF4 CCDC126 CCDC47 CCDC53 CD79B CDC16 CDK6 CDO1 CENPW CEP120 CHMP1A CMIP CRIPAK CROCC CSPG4P11 CTD-3074O7.12 CTD-3076O17.1 DCAF16 DDB2 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 ESPNP FAM136A FER GDF5 GNA12 GOLGA6L5 GPR126 GPX1 GSDMC H1FX H6PD HABP4 HAPLN3 HIST2H2AA3 HORMAD2 ICAM2 IPO8 JMJD4 KIAA1614 L3MBTL3 LOC147727 LOXL1-AS1 LRRC37A2 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTCH2 MTTP MYO1F MYO9A NARFL NCAPG NCOA1 NOV NOX4 OTUD4 PACSIN1 PDIK1L PIAS4 PIGC PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PPA2 PSMC3 PSMC5 PTCH1 QSOX2 RAB24 RAD9A RFT1 RGS12 RP11-108M9.5 RP11-182J1.14 RP11-182J1.16 RP11-196G18.24 RP11-250B2.6 RP1-125I3.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-669E14.6 RP11-78I14.1 RP1-93H18.7 RPS20 RPS6KA1 RSPH6A SCAND2P SCMH1 SEPN1 SERPINF1 SH3BGRL3 SLC16A9 SLC25A21 SMARCD2 TGFB2 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 TSPAN3 TULP4 U91328.21 UBE2Q2P1 UBXN2A WNT3 WNT4 ZC3H11B ZCCHC24 ZHX2 ZNF169 ZNF500 ZNF638 ZNF76
Number of full sisters	1.54	1	0	0.0	0.00	1.0e+00	ADAMTS6
Suffer from 'nerves'	1.68	2	2	4.4	0.98	2.5e-02	C1QTNF4 MTCH2
Overall health rating	1.79	10	4	8.9	-0.92	2.5e-05	CCDC87 CTD-3074O7.12 CTSF DCAF16 FOXP1 GPX1 KAT8 RP11-1055B8.4 SETD1A ZDHHC24
Age at last live birth	1.36	1	1	2.2	0.00	1.0e+00	GPX1
Leg pain on walking	1.19	1	0	0.0	0.00	1.0e+00	WNT3
Knee pain experienced in last month	1.61	2	2	4.4	0.00	1.0e+00	GDF5 LOC147727
Hypertension (Self-reported)	1.92	16	7	15.6	-0.84	7.8e-06	ACP2 C11orf49 CHMP1A CTC-228N24.3 DCAF16 DDB2 FBN2 HSD3B7 KAT8 MYST1 NCAPG PIAS4 RP11-1055B8.4 SETD1A U91328.21 ZNF408
Forced expiratory volume in 1-second (FEV1), predicted	7.30	62	43	95.6	0.97	3.8e-48	AC103965.1 ADCY3 ANAPC10 ATP13A2 C1QTNF4 CD79B CDK6 CENPW CHMP1A CSPG4P11 CTD-3076O17.1 DCAF16 DLEU2 E2F1 EBPL EFEMP1 GDF5 GNA12 GOLGA6L5 GPR126 GSDMC H1FX HIST2H2AA3 JMJD4 L3MBTL3 LEMD3 LOXL1-AS1 MAN2C1 MPHOSPH6 MRPL42 MST1L MST1P2 MTCH2 MYO1F MYO9A NARFL NCAPG OTUD4 PACSIN1 PIP4K2B PSMC5 PTCH1 RAB24 RAD9A RP11-182J1.14 RP11-182J1.16 RP11-196G18.24 RP11-435O5.4 RP11-977G19.11 SCMH1 SLC16A9 SMARCD2 TGFB2 TMEM180 TP53INP2 TRA2A TSEN15 UBE2Q2P1 ZHX2 ZNF500 ZNF638 ZNF76
Whole body fat-free mass	6.05	102	87	193.3	0.93	1.6e-52	AC083843.1 ADAM11 ANAPC10 AOC1 AP3B1 ARFGEF2 AXIN2 C1QTNF4 CCDC47 CCDC53 CD79B CDC16 CDK6 CENPW CEP120 CHMP1A CNKSR1 CRIPAK CTC-228N24.3 DCAF16 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 FLJ33630 GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LOC147727 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F MYST1 NARFL NCAPG NCOA1 NOV NOX4 OTUD4 PACSIN1 PDIK1L PIGC PIP4K2B PLEKHA1 PLEKHM1P PPA2 PPP3R1 PSMC3 PSMC5 PTCH1 RAB24 RAD9A RIN3 RP11-109P14.10 RP11-250B2.6 RP1-125I3.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-65J21.3 RP11-78I14.1 RP11-977G19.11 RPS20 RPS6KA1 SCMH1 SERPINF1 SETD1A SH3BGRL3 SLC12A2 SMARCD2 SNAI3-AS1 TGFB2 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76
Leg fat-free mass (right)	5.32	93	70	155.6	0.91	2.5e-41	AC083843.1 ADAM11 ANAPC10 AOC1 AP3B1 ARFGEF2 AXIN2 CCDC53 CD79B CDC16 CDK6 CENPW CEP120 CNKSR1 CRIPAK CTC-228N24.3 DCAF16 DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 FLJ33630 GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HIST2H2AA3 HORMAD2 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LOC147727 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F MYST1 NARFL NCAPG NCOA1 NOV NOX4 OTUD4 PACSIN1 PDIK1L PIP4K2B PLEKHA1 PLEKHM1P PPA2 PPP3R1 PSMC3 PSMC5 PTCH1 RAB24 RAD9A RIN3 RP11-109P14.10 RP11-196G18.24 RP11-250B2.6 RP1-125I3.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-78I14.1 RP11-977G19.11 RPS20 SCMH1 SETD1A SH3BGRL3 SLC12A2 SMARCD2 SNAI3-AS1 TGFB2 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZCCHC24 ZNF500 ZNF638
Arm fat percentage (left)	2.92	39	27	60.0	-0.67	2.1e-07	AAGAB ACP2 ADCY3 ANKRD13B AP3B1 ARFGEF2 C1QTNF4 CASC10 CCDC171 CCDC87 CD79B CENPW CTSF DCAF16 DDB2 FBN2 FOXP1 GNA12 GPX1 HABP4 HIST2H2AA3 HSD3B7 KAT8 LIME1 MTCH2 MYST1 NCAPG NFAT5 NOB1 NOV PIAS4 PIGF PSMC5 RP11-196G18.24 RP11-78I14.1 SAR1B SETD1A STX1B ZNF76
Average weekly red wine intake	1.41	1	1	2.2	0.00	1.0e+00	FOXP1
Handedness (chirality/laterality): Left-handed	1.54	5	3	6.7	0.98	3.6e-03	ARL17A LRRC37A2 NSFP1 RP11-669E14.6 WNT3
Mood swings	1.91	7	6	13.3	-0.66	1.1e-01	C1QTNF4 GPX1 LRRC37A LRRC37A2 RP11-669E14.6 STX1B WNT3
Loneliness, isolation	1.71	6	3	6.7	0.33	4.8e-01	ARFGEF2 C1QTNF4 GPX1 LRRC37A2 MTCH2 WNT3
Long-standing illness, disability or infirmity	1.53	1	1	2.2	0.00	1.0e+00	CCDC171
Diabetes diagnosed by doctor	1.78	2	1	2.2	0.00	1.0e+00	CENPW ZCCHC24
Qualifications: nursing, teaching	1.48	1	0	0.0	0.00	1.0e+00	AXIN2
Mouth/teeth dental problems: Mouth ulcers	1.54	5	5	11.1	-0.73	1.6e-01	CTSS LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Medication for cholesterol	1.76	3	0	0.0	0.00	1.0e+00	CHMP1A KAT8 STX1B
Asthma (self-reported)	1.55	5	3	6.7	-0.56	3.3e-01	AAGAB AHI1 CTD-3074O7.12 U91328.21 ZNF76
Osteoporosis (self-reported)	1.07	1	0	0.0	0.00	1.0e+00	MRGPRF
Osteoarthritis (self-reported)	1.16	1	0	0.0	0.00	1.0e+00	LOC147727
Smoking status: Current	1.18	2	0	0.0	0.00	1.0e+00	LIME1 MTCH2
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.85	42	23	51.1	0.93	6.1e-21	ANGPTL1 ASPSCR1 C10orf11 CDC123 CEP120 CLUAP1 CNKSR1 CTSS DHDDS GPR126 HSD3B7 INTS12 JAG1 KAT8 LIME1 LRRC37A LRRC37A2 MYST1 NOB1 PDIK1L PPA2 PSMA4 QSOX2 RIN3 RNF123 ROM1 RP11-196G11.2 RP11-250B2.6 RP1-125I3.2 RP11-382A20.2 RP11-669E14.6 RP11-967K21.1 RP1-93H18.7 SETD1A SH3BGRL3 STX1B TRIM63 U91328.21 WHAMM WNT3 WNT4 ZNF76
Whole body water mass	6.01	102	89	197.8	0.93	1.8e-52	AC083843.1 ADAM11 ANAPC10 AOC1 AP3B1 ARFGEF2 AXIN2 C1QTNF4 CCDC53 CD79B CDC16 CDK6 CENPW CEP120 CHMP1A CNKSR1 CRIPAK CTC-228N24.3 DCAF16 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 FLJ33630 GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LOC147727 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MYO1F MYST1 NARFL NCAPG NCOA1 NOV NOX4 OTUD4 PACSIN1 PDIK1L PIGC PIP4K2B PLEKHA1 PLEKHM1P PPA2 PPP3R1 PSMC3 PSMC5 PTCH1 RAB24 RAD9A RIN3 RP11-109P14.10 RP11-250B2.6 RP1-125I3.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-65J21.3 RP11-78I14.1 RP11-977G19.11 RPS20 RPS6KA1 SCMH1 SERPINF1 SETD1A SH3BGRL3 SLC12A2 SMARCD2 SNAI3-AS1 TGFB2 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76
Leg predicted mass (right)	5.33	93	70	155.6	0.91	8.7e-42	AC083843.1 ADAM11 ANAPC10 AOC1 AP3B1 ARFGEF2 AXIN2 CCDC53 CD79B CDC16 CDK6 CENPW CEP120 CNKSR1 CRIPAK CTC-228N24.3 DCAF16 DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 FLJ33630 GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HIST2H2AA3 HORMAD2 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LOC147727 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F MYST1 NARFL NCAPG NCOA1 NOV NOX4 OTUD4 PACSIN1 PDIK1L PIP4K2B PLEKHA1 PLEKHM1P PPA2 PPP3R1 PSMC3 PSMC5 PTCH1 RAB24 RAD9A RIN3 RP11-109P14.10 RP11-196G18.24 RP11-250B2.6 RP1-125I3.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-78I14.1 RP11-977G19.11 RPS20 SCMH1 SETD1A SH3BGRL3 SLC12A2 SMARCD2 SNAI3-AS1 TGFB2 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZCCHC24 ZNF500 ZNF638
Arm fat mass (left)	2.23	31	22	48.9	-0.24	1.7e-01	AAGAB ADCY3 AP3B1 C1QTNF4 CASC10 CCDC171 CCDC87 CDK6 CEP120 CTSF FOXP1 GDF5 GNA12 GPX1 HIST2H2AA3 HSD3B7 KAT8 L3MBTL3 LIME1 MTCH2 MYST1 NOB1 OTUD4 PACSIN1 PIAS4 RP11-196G18.24 RP11-78I14.1 SETD1A STX1B TP53INP2 ZNF500
Number of self-reported non-cancer illnesses	1.84	3	1	2.2	0.00	1.0e+00	AAGAB CCDC87 CTSF
Average weekly champagne plus white wine intake	1.32	4	0	0.0	0.99	1.4e-02	LRRC37A LRRC37A2 RP11-669E14.6 WNT3
Miserableness	1.76	10	6	13.3	-0.63	4.9e-02	C11orf49 C1QTNF4 GPX1 HORMAD2 LOXL1-AS1 LRRC37A LRRC37A2 MTCH2 RP11-669E14.6 WNT3
Guilty feelings	1.56	5	1	2.2	-0.70	1.8e-01	C1QTNF4 LRRC37A2 RP11-669E14.6 UBXN2A WNT3
Financial situation satisfaction	1.12	1	1	2.2	0.00	1.0e+00	GPX1
Medication: Blood pressure	1.68	6	3	6.7	0.01	9.8e-01	ACP2 CHMP1A DDB2 KAT8 LRRC37A2 RP11-1055B8.4
Supplements: Fish oil (including cod liver oil)	1.49	2	0	0.0	0.00	1.0e+00	CCDC87 NFAT5
High cholesterol (Self-reported)	1.84	5	2	4.4	-0.99	2.2e-03	FAM136A LOC147727 MYST1 RGS12 SIK3
Medication: Bendroflumethiazide	1.39	3	0	0.0	0.00	1.0e+00	ACP2 CHMP1A KAT8
Medication: Paracetamol	1.63	7	4	8.9	-0.80	3.0e-02	CASC10 GPX1 LRRC37A LRRC37A2 RP11-669E14.6 U91328.21 WNT3
Medication: Atorvastatin	1.24	1	0	0.0	0.00	1.0e+00	SIK3
Ever smoked	1.20	2	0	0.0	0.00	1.0e+00	C4orf14 PSMA4
Basal metabolic rate	5.42	99	78	173.3	0.92	8.3e-47	AC083843.1 ADAM11 ANAPC10 AOC1 AP3B1 ARFGEF2 AXIN2 CCDC53 CD79B CDC16 CDK6 CENPW CEP120 CHMP1A CNKSR1 CRIPAK CTC-228N24.3 DCAF16 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 FLJ33630 GDF5 GNA12 GPR126 GPX1 GSDMC H1FX HABP4 HAPLN3 HORMAD2 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LOC147727 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F MYST1 NARFL NCAPG NCOA1 NOV NOX4 OTUD4 PACSIN1 PDIK1L PIGC PIP4K2B PLEKHA1 PPA2 PPP3R1 PSMC3 PSMC5 PTCH1 RAB24 RAD9A RIN3 RP11-109P14.10 RP11-182J1.16 RP11-250B2.6 RP1-125I3.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-65J21.3 RP11-78I14.1 RP11-977G19.11 RPS20 SCMH1 SERPINF1 SETD1A SH3BGRL3 SLC12A2 SMARCD2 TGFB2 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 TULP4 UBXN2A WNT4 ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76
Leg fat percentage (left)	3.69	45	29	64.4	-0.84	4.3e-16	AAGAB AC103965.1 ADCY3 ANKRD13B ARFGEF2 C1QTNF4 CASC10 CCDC171 CD79B CENPW CTC-228N24.3 DARS DCAF16 FLJ33630 FOXN2 FOXP1 GDF5 GPX1 GSK3A HABP4 HSD3B7 KAT8 LIME1 MTCH2 MYST1 NCAPG NOB1 NOV PIAS4 PIGF PLEKHM1P PSMC3 PSMC5 PTCH1 RFT1 RIN3 RP11-196G11.2 RP5-890E16.2 SAR1B SETD1A SLC12A2 SMARCD2 STX1B ZCCHC24 ZNF76
Arm fat-free mass (left)	5.13	91	73	162.2	0.90	3.9e-39	AC083843.1 ADAM11 ANAPC10 AOC1 AP3B1 ARFGEF2 AXIN2 CASC10 CCDC53 CD79B CDC16 CDK6 CENPW CEP120 CHMP1A CNKSR1 CRIPAK DCAF16 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 GDF5 GNA12 GPR126 GPX1 GSDMC H1FX HABP4 HAPLN3 HORMAD2 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LOC147727 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F MYST1 NARFL NCAPG NCOA1 NOV OTUD4 PACSIN1 PDIK1L PIGC PLEKHA1 PPA2 PPP3R1 PSMC3 PSMC5 PTCH1 RAB24 RAD9A RIN3 RP1-125I3.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-65J21.3 RP11-78I14.1 RP11-977G19.11 RPS20 RPS6KA1 SCMH1 SERPINF1 SETD1A SH3BGRL3 SMARCD2 TGFB2 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 UBXN2A ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76
Number of operations (self-reported)	1.74	5	2	4.4	0.57	3.2e-01	CASC10 CTC-228N24.3 FLJ33630 GNA12 PPA2
Average weekly beer plus cider intake	1.20	1	0	0.0	0.00	1.0e+00	RNF123
Irritability	1.89	10	5	11.1	-0.52	8.5e-02	GPX1 HSD3B7 L3MBTL3 LRRC37A LRRC37A2 RP11-196G11.2 RP11-669E14.6 SETD1A STX1B WNT3
Fractured/broken bones in last 5 years	1.58	1	0	0.0	0.00	1.0e+00	AAGAB
Diastolic blood pressure, automated reading	1.63	19	9	20.0	-0.56	6.8e-03	AAGAB ACP2 CASC10 CEP120 CHMP1A DARS DCAF16 GPX1 HSD3B7 JAG1 KAT8 MYO9A MYST1 NCAPG NOV SCMH1 SETD1A STX1B U91328.21
Myopia	1.56	1	1	2.2	0.00	1.0e+00	QSOX2
Vascular/heart problems diagnosed by doctor	1.89	12	8	17.8	0.85	6.1e-05	ACP2 C11orf49 CHMP1A DCAF16 DDB2 KAT8 MYST1 NCAPG NFAT5 PIAS4 SETD1A ZNF408
Cholesterol lowering medication	2.03	2	0	0.0	0.00	1.0e+00	ANKRD13B SIK3
Pain experienced in last month	1.61	3	1	2.2	0.00	1.0e+00	CENPW GPX1 STX1B
Deep venous thrombosis (DVT) (self-reported)	1.31	1	1	2.2	0.00	1.0e+00	CACFD1
Heart disease (siblings)	1.52	1	0	0.0	0.00	1.0e+00	TP53INP2
Pack years of smoking	2.23	4	1	2.2	-0.86	1.4e-01	CYB561 GPX1 PIAS4 PSMA4
Impedance of whole body	3.24	55	41	91.1	0.23	6.8e-02	AC083843.1 AC103965.1 ADCY3 AOC1 ATP13A2 CD79B CENPW CEP120 CROCC CSPG4P11 CTC-228N24.3 CTD-3076O17.1 EFEMP1 FBN2 FER FLJ33630 GDF5 GOLGA6L5 GPR126 GPX1 H6PD HIST2H2AA3 HORMAD1 KAT8 L3MBTL3 LOXL1-AS1 LRRC37A LRRC37A2 MRGPRF MRPL42 MST1L MST1P2 NSFP1 OTUD4 PACSIN1 PPA2 PSMC5 RAD9A RFT1 RIN3 ROM1 RP11-108M9.5 RP11-182J1.14 RP11-182J1.16 RP11-196G18.24 RP11-425D10.10 RP11-669E14.6 RP5-890E16.2 RPS20 SCAND2P SCMH1 SLC12A2 TSPAN3 UBE2Q2P1 WNT3
Leg fat mass (left)	2.29	32	24	53.3	-0.30	7.0e-02	AAGAB AC103965.1 ADCY3 AP3B1 C1QTNF4 CASC10 CCDC171 CDK6 CTC-228N24.3 DARS FLJ33630 FOXP1 GNA12 GPX1 HSD3B7 KAT8 L3MBTL3 LIME1 MPHOSPH6 MTCH2 MYST1 NOB1 OTUD4 PACSIN1 PIAS4 RAD9A RP11-182J1.16 RP11-78I14.1 SAR1B SETD1A STX1B ZNF500
Arm predicted mass (left)	5.08	93	70	155.6	0.89	6.7e-38	AC083843.1 ADAM11 ANAPC10 AOC1 AP3B1 ARFGEF2 AXIN2 CASC10 CCDC53 CD79B CDC16 CDK6 CENPW CEP120 CHMP1A CNKSR1 CRIPAK DCAF16 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 GDF5 GNA12 GPR126 GPX1 GSDMC H1FX HABP4 HAPLN3 HORMAD2 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LOC147727 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F MYST1 NARFL NCAPG NCOA1 NOV OTUD4 PACSIN1 PDIK1L PIGC PLEKHA1 PPA2 PPP3R1 PSMC3 PSMC5 PTCH1 RAB24 RAD9A RIN3 RP11-250B2.6 RP1-125I3.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-65J21.3 RP11-78I14.1 RP11-977G19.11 RPS20 RPS6KA1 SCMH1 SERPINF1 SETD1A SH3BGRL3 SMARCD2 STX1B TGFB2 TMEM180 TP53INP2 TRA2A TRIM63 TSEN15 UBXN2A ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76

Associations by panel

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Adipose Subcutaneous	62	1.78	3.8
GTEx	Adipose Visceral Omentum	40	1.96	4.2
GTEx	Adrenal Gland	29	1.99	3.8
GTEx	Artery Aorta	56	1.88	4.0
GTEx	Artery Coronary	28	2.37	4.4
GTEx	Artery Tibial	80	2.13	3.9
GTEx	Brain Caudate basal ganglia	12	1.30	3.6
GTEx	Brain Cerebellar Hemisphere	36	2.42	4.1
GTEx	Brain Cerebellum	42	2.12	4.0
GTEx	Brain Cortex	27	2.61	4.2
GTEx	Brain Frontal Cortex BA9	16	1.73	4.0
GTEx	Brain Hippocampus	15	2.86	4.5
GTEx	Brain Hypothalamus	17	2.88	4.4
GTEx	Brain Nucleus accumbens basal ganglia	20	2.31	4.3
GTEx	Brain Putamen basal ganglia	9	1.44	3.9
GTEx	Breast Mammary Tissue	37	1.87	4.1
GTEx	Breast Mammary Tissue (Male)	32	2.68	4.5
GTEx	Breast Mammary Tissue (Female)	27	1.64	3.9
GTEx	Cells EBV-transformed lymphocytes	35	2.46	4.4
GTEx	Cells Transformed fibroblasts	71	1.69	3.7
GTEx	Colon Sigmoid	28	1.92	4.1
GTEx	Colon Transverse	42	2.03	3.9
GTEx	Esophagus Gastroesophageal Junction	31	2.15	4.1
GTEx	Esophagus Mucosa	70	2.11	3.9
GTEx	Esophagus Muscularis	64	1.98	4.1
GTEx	Heart Atrial Appendage	39	2.47	4.3
GTEx	Heart Left Ventricle	25	1.63	3.9
GTEx	Liver	20	2.79	4.2
GTEx	Lung	68	2.37	4.0
GTEx	Muscle Skeletal	44	1.52	3.7
GTEx	Nerve Tibial	80	1.85	3.8
GTEx	Ovary	23	2.53	4.9
GTEx	Pancreas	31	1.90	3.9
GTEx	Pituitary	33	2.96	4.5
GTEx	Prostate	16	1.92	3.9
GTEx	Skin Not Sun Exposed Suprapubic	51	2.07	3.9
GTEx	Skin Sun Exposed Lower leg	70	1.92	4.0
GTEx	Small Intestine Terminal Ileum	12	2.60	4.7
GTEx	Spleen	28	1.98	4.1
GTEx	Stomach	36	2.48	4.1
GTEx	Testis	65	2.06	4.1
GTEx	Thyroid	66	1.65	3.9
GTEx	Uterus	15	2.65	4.8
GTEx	Vagina	15	2.36	4.1
GTEx	Whole Blood	42	2.11	3.8
METSIM	Adipose	55	1.19	3.2
NTR	Blood	35	1.46	3.2
ROSMAP	Brain Pre-frontal Cortex	53	1.21	3.2
YFS	Blood	52	1.13	3.1
CommonMind	Brain Pre-frontal Cortex	68	1.27	3.2
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	23	1.39	3.3
The Cancer Genome Atlas	Breast Invasive Carcinoma	64	1.45	3.3
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	20	1.82	3.6
The Cancer Genome Atlas	Colon Adenocarcinoma	30	1.45	3.4
The Cancer Genome Atlas	Esophageal Carcinoma	12	1.75	3.9
The Cancer Genome Atlas	Glioblastoma Multiforme	19	1.86	3.8
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	43	1.58	3.4
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	57	1.39	3.3
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	20	0.98	3.2
The Cancer Genome Atlas	Brain Lower Grade Glioma	68	1.58	3.4
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	16	1.45	3.4
The Cancer Genome Atlas	Lung Adenocarcinoma	46	1.57	3.4
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	36	1.44	3.3
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	21	1.32	3.3
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	16	0.96	3.3
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	21	1.58	3.4
The Cancer Genome Atlas	Prostate Adenocarcinoma	64	1.38	3.4
The Cancer Genome Atlas	Rectum Adenocarcinoma	15	2.17	3.6
The Cancer Genome Atlas	Soft Tissue Sarcoma	18	1.69	3.6
The Cancer Genome Atlas	Skin Cutaneous Melanoma	7	1.31	3.5
The Cancer Genome Atlas	Stomach Adenocarcinoma	23	1.37	3.3
The Cancer Genome Atlas	Testicular Germ Cell Tumors	11	0.86	3.1
The Cancer Genome Atlas	Thyroid Carcinoma	65	1.26	3.2
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	8	1.57	3.7