TWAS
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Models
Genes
Traits
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Traits
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Forced vital capacity (FVC), Best measure
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chr19:741,758-1,238,899
Best TWAS P=8.68e-08 · Best GWAS P=7.62e-08 conditioned to 1
0.8M
0.9M
1M
1.1M
1.2M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
WDR18
0.38
0.13
lasso
4
0.16
5.5e-07
5.4
5.4
8.7e-08
0.95
0
1
TRUE