Best TWAS P=6.75e-10 · Best GWAS P=2.25e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | ILF3-AS1 | 0.11 | 0.00 | lasso | 4 | 0.00 | 2.5e-01 | 6.2 | -5.9 | 4.8e-09 | -0.75 | 0.02 | 0.87 | FALSE |
2 | GTEx | Nerve Tibial | ILF3-AS1 | 0.14 | 0.04 | lasso | 3 | 0.08 | 3.8e-06 | 6.2 | -6.1 | 1.3e-09 | -0.77 | 0.01 | 0.98 | FALSE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LOC147727 | 0.07 | 0.02 | lasso | 2 | 0.02 | 5.4e-03 | 6.2 | -6.2 | 6.8e-10 | -0.97 | 0.01 | 0.87 | TRUE |