Best TWAS P=7.54e-10 · Best GWAS P=3.36e-10 conditioned to 0.14
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Thyroid Carcinoma | HORMAD2 | 0.06 | 0.04 | enet | 10 | 0.07 | 5.7e-07 | 6.3 | -6.2 | 7.5e-10 | -0.94 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | MTMR3 | 0.21 | 0.08 | blup | 72 | 0.16 | 2.5e-15 | 5.7 | -5.5 | 4.6e-08 | -0.78 | 0.01 | 0.99 | FALSE |