Best TWAS P=1.36e-07 · Best GWAS P=1.25e-06 conditioned to 0.147
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | FOXN2 | 0.09 | 0.03 | lasso | 3 | 0.01 | 5.6e-02 | -4.5 | -5.3 | 1.4e-07 | 0.73 | 0.01 | 0.89 | TRUE |
| 2 | GTEx | Adrenal Gland | FOXN2 | 0.24 | 0.11 | lasso | 6 | 0.16 | 2.8e-06 | 3.9 | -5.2 | 1.8e-07 | 0.65 | 0.06 | 0.77 | FALSE |
| 3 | GTEx | Lung | FOXN2 | 0.37 | 0.24 | lasso | 5 | 0.24 | 2.5e-18 | -4.8 | -5.1 | 2.7e-07 | 0.98 | 0.00 | 0.99 | FALSE |
| 4 | GTEx | Prostate | FOXN2 | 0.21 | 0.14 | lasso | 3 | 0.17 | 4.2e-05 | -4.8 | -5.2 | 2.4e-07 | 0.98 | 0.00 | 0.91 | FALSE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | FOXN2 | 0.26 | 0.21 | lasso | 6 | 0.21 | 2.4e-26 | -4.8 | -5.3 | 1.4e-07 | 0.98 | 0.00 | 0.99 | FALSE |